$AUPH let us get crazy here (just for fun) and say that peak sales hit $3b. Subtract 300m for operation of the business. So, 2.7b. then pick your p/e ratio between 10 and 15. Let's say 12.5 x 2.7b = 33.75 billion MC. With two more assets firmly along in the pipeline. Sure, I'll take a buyout but I'm also willing to hold longer. As someone put it here---win-win.