$BCRX @R8plus @nickpd @aferslid My comparison of efficacy of Galidesivir vs Remdesivir part 1/2 Doses in mg Remdesivir IV dose 200 mg loading, 100 mg maintenance/12 h Molecular weight 603 Assuming 70 kg patient: Galidesivir IV dose 700 mg loading, 140 mg maintenance/12 h (cohort 1) Galidesivir IV dose 700 mg loading, 350 mg maintenance/12 h (cohort 2) Galidesivir IV dose 1400 mg loading, 350 mg maintenance/12 h (cohort 3) Molecular weight 265 Doses in mmol Remdesivir IV dose 0.332 mmol loading, 0.166 mg maintenance/12 h Assuming 70 kg patient: Galidesivir IV dose 2.64 mmol loading, 0.528 mmol maintenance/12 h (cohort 1) Galidesivir IV dose 2.64 mmol loading, 1.32 mmol maintenance/12 h (cohort 2) Galidesivir IV dose 5.28 mmol loading, 1.32 mmol maintenance/12 h (cohort 3)
  • 18
18 Likes