$SIGA Tpoxx is a clear medical winner for MPXV. Fresh off the press! Tpoxx aka ST-246 is almost 2000x more potent than cidofivir. 12.7 nanomolar IC50 by TPOXX is a winner!!! All data point to a clear successful therapy for MPXV, consistent with recent clinical findings published in the Lancet and BMJ, and anecdotal reports of patients in Twitter!!! EUA definitely soon!