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GRAIL, Inc. operates as a commercial-stage healthcare company, which engages in the development of a technology for early detection of cancer. It utilizes machine learning, software, and automation to detect and identify multiple deadly cancer types in earlier stages. The company was founded by Jeffrey T. Huber, William H. Rastetter, Mostafa Ronaghi, and Richard D. Klausner on September 11, 2015 and is headquartered in Menlo Park, CA.

GRAIL Inc.

GRAIL is trending due to a significant after-hours price drop following its NHS-Galleri cancer screening trial missing its primary endpoint for statistically significant late-stage cancer detection. The community is sharply divided, with many calling the market reaction an extreme overreaction given the test's perceived utility, the company's solid financials, and its ongoing FDA approval process, while others anticipate further declines and question the test's overall effectiveness.

Candel Therapeutics, Inc. is a clinical stage biotechnology company, which engages in the development and commercialization of viral immunotherapies. Its pipeline includes CAN-2409 and CAN-3110. The company was founded by Estuardo Aguilar-Cordova in 2002 and is headquartered in Needham, MA.

Candel Therapeutics Inc

Candel Therapeutics is trending following a mixed market reaction to its dual financing announcement: a proposed $100 million public stock offering and a $100 million royalty funding deal with RTW Investments. While some investors express significant concern over dilution, others view the combined capital as a strategic move to secure a robust runway for its advanced pipeline and upcoming BLA submission, enhancing long-term commercialization flexibility.

Ardelyx, Inc. is a biopharmaceutical company, which engages in the business of developing and commercializing biopharmaceutical products. The firm is also involved in developing a unique and innovative platform that enables the discovery of new biological mechanisms and pathways to develop potent and efficacious therapies that minimize the side effects and drug-drug interactions frequently encountered with traditional, systemically absorbed medicines. The company was founded by Dominique Charmot, Peter G. Schultz, and Jean M. Frechet in October 2007 and is headquartered in Waltham, MA.

Ardelyx Inc

Ardelyx is trending following its recent revenue growth and the significant extension of its IBSRELA and XPHOZAH patent protection into 2042, fueling community debate on long-term value creation through increased development spending versus immediate profitability, alongside continued speculation about potential strategic partnerships.

Celsius Holdings, Inc. engages in the development, marketing, sale, and distribution of functional drinks and liquid supplements. It also offers post-workout functional energy drinks and protein bars. The company was founded in April 2004 and is headquartered in Boca Raton, FL.

Celsius Holdings Inc

Celsius Holdings is trending higher after its CAGNY conference presentation emphasized strong distribution and shelf space gains, fueling community discussion around accelerated growth and intensifying speculation of a potential PepsiCo acquisition.

Transocean Ltd. engages in the provision of offshore contract drilling services for oil and gas wells. It also owns and operates offshore drilling fleets such as ultra-deepwater, harsh environment, deepwater, and midwater rigs. The company was founded in 1953 and is headquartered in Steinhausen, Switzerland.

Transocean Ltd

Transocean is trending due to its significant all-stock merger with Valaris, poised to create a dominant offshore drilling entity with a substantial backlog and anticipated cost synergies. The community is actively discussing a potential short squeeze and a long-awaited turnaround for the company amidst robust demand in the energy sector.

Klarna Group Plc is a global digital bank and flexible payments provider. It operates through an AI-powered payments and commerce network that empowers people to pay smarter, with a mission to be available everywhere, for everything. The company was founded by Gustav Erik Niklas Adalberth, Karl Anders Victor Jacobsson, and Sebastian Marcin Siemiatkowski in 2005 and is headquartered in London, the United Kingdom.

Klarna Group plc

Klarna (KLAR) is experiencing extreme volatility and trending heavily after its latest earnings report revealed robust revenue growth and expanding user base, especially in the US, but also a net loss driven by a significant increase in loan loss provisions. The community is sharply divided, with many calling the 'buy now, pay later' business model unsustainable and predicting further declines, while others view the sell-off as an 'overreaction' and a prime buying opportunity, citing strong underlying growth and strategic partnerships.

AppLovin Corp. engages in the development and operation of a mobile marketing platform. It offers AppDiscovery, MAX, Adjust, and SparkLabs. Its software-based platform caters to mobile application developers to improve the marketing and monetization of applications. The company was founded by Andrew Karam, John Krystynak, and Adam Foroughi in 2011 and is headquartered in Palo Alto, CA.

Applovin Corp - Ordinary Shares - Class A

Applovin Corp

AppLovin is gaining significant attention amid strong rumors of a potential partnership with OpenAI to monetize ChatGPT through ads, fueling investor excitement and a desire for a short squeeze. This speculation comes as the community debates the stock's recent sharp decline, which many view as an unjustified overreaction to broader AI disruption fears, given the company's robust earnings and advanced AI ad-tech.

One Stop Systems, Inc. engages in the design, manufacture, and marketing of computing modules and systems targeting edge deployments. It deals with the design and manufacture of high-performance customized computer and flash arrays, in-flight entertainment, and connectivity and value-added reseller with minimal customization. It operates through the OSS and OSS Europe segments. The company was founded by Stephen D. Cooper and Mark Gunn in 1998 and is headquartered in Escondido, CA.

One Stop Systems Inc

One Stop Systems (OSS) is generating significant buzz following recent multi-million dollar defense contracts for its Edge AI solutions, notably with the U.S. Navy's P-8A Poseidon program, and new commercial robotics business. Community discussion highlights the company's undervalued position as a pure-play in high-growth Edge AI for defense and industrial applications, alongside expectations of further major contract wins and potential short squeeze dynamics.

Kratos Defense & Security Solutions, Inc. engages in the provision of mission critical products, services and solutions for United States national security priorities. It operates through the Kratos Government Solutions (KGS) and Unmanned Systems (US) segments. The KGS segment consists of an aggregation of KGS operating segments, including microwave electronic products, space, satellite and cyber, training solutions. The US segment refers to the unmanned aerial, unmanned ground, unmanned seaborne and related command, control and communications system businesses. The company was founded on December 19, 1994, and is headquartered in Round Rock, TX.

Kratos Defense & Security Solutions Inc

Kratos Defense & Security Solutions is trending amidst surging defense spending expectations following proposed budget increases and escalating global tensions. The community is focused on recent substantial contract wins in hypersonics, unmanned systems, and defense testing, which, combined with bullish technical indicators, is fueling optimism for its established uptrend.

Lumentum Holdings, Inc. engages in the provision of optical and photonic products. It operates through the Cloud and Networking, and Industrial Tech segments. The Cloud and Networking segment refers to a portfolio of optical and photonic components, modules, and subsystems. The Industrial Tech segment includes solid-state lasers, kilowatt-class fiber lasers, ultrafast lasers, diode lasers, and gas lasers. The company was founded in 1979 and is headquartered in San Jose, CA.

Lumentum Holdings Inc

Lumentum Holdings is trending due to robust earnings that beat expectations and strong forward guidance, fueled by accelerating demand for optical components critical to AI data center infrastructure. The stock's parabolic surge is sparking intense debate, with many celebrating its powerful momentum and short squeeze potential, while others warn of extreme overvaluation and heavy insider selling.

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Notable Thursday Option Activity: SLS, MDGL, ZG

Looking at options trading activity among components of the Russell 3000 index, there is noteworthy activity today in SELLAS Life Sciences Group Inc (Symbol: SLS), where a total volume of 38,228...

SELLAS Life Sciences Group (NASDAQ:SLS) Shares Up 9.8% - Here's Why

SELLAS Life Sciences Group (NASDAQ:SLS) Trading Up 9.8% - Here's What Happened...

SELLAS Life Sciences Group (NASDAQ:SLS) Shares Gap Down - Should You Sell?

SELLAS Life Sciences Group (NASDAQ:SLS) Shares Gap Down - Here's Why...

SELLAS Life Sciences Group, Inc. (NASDAQ:SLS) Short Interest Down 14.9% in January

SELLAS Life Sciences Group, Inc. (NASDAQ:SLS - Get Free Report) saw a significant decline in short interest in January. As of January 15th, there was short interest totaling 42,044,430 shares, a...

SELLAS Life Sciences Group (NASDAQ:SLS) Shares Down 7.4% - Should You Sell?

SELLAS Life Sciences Group (NASDAQ:SLS) Trading Down 7.4% - Here's What Happened...

SELLAS Life Sciences Group (NASDAQ:SLS) Trading 9.2% Higher - Still a Buy?

SELLAS Life Sciences Group (NASDAQ:SLS) Shares Up 9.2% - Here's Why...

SELLAS Life Sciences Group, Inc. (NASDAQ:SLS) Short Interest Up 22.1% in December

SELLAS Life Sciences Group, Inc. (NASDAQ:SLS - Get Free Report) saw a large growth in short interest during the month of December. As of December 31st, there was short interest totaling 49,429,420...

SELLAS Life Sciences Group (NASDAQ:SLS) Stock Price Down 5.5% - Should You Sell?

SELLAS Life Sciences Group (NASDAQ:SLS) Stock Price Down 5.5% - Should You Sell...

<ul class="summary-bullets"><li>The European study is expected to enroll 40 newly diagnosed AML patients.</li><li>Enrollment at U.S. sites is planned to begin in the first quarter of 2026, with European enrollment anticipated in the second quarter of 2026, the company said.</li><li>SLS stock is on track to end in the red in five of the last seven sessions.</li></ul>SELLAS Life Sciences Group Inc (SLS) stock was in the spotlight after it signed an agreement with IMPACT-AML (Acute Myeloid Leukemia) to expand the clinical development of SLS009, a targeted cancer therapy, into Europe.<a href="https://stocktwits.com/symbol/SLS">SLS stock</a> has been trending down lately and is on track to end in the red in five of the last seven sessions. It was trading 3.2% lower. Last week, investors booked profits amid dilution concerns after Sellas reported $26.5 million in proceeds from the exercise of common stock warrants, in addition to its estimated cash and cash equivalents of $71.8 million as of December-end.<h2 class="st-heading-2">IMPACT-AML Tie Up</h2>The IMPACT-AML, a pan-European initiative within the EU Mission Cancer program, will conduct a European clinical study evaluating SLS009, providing SELLAS access to multiple clinical sites and a broader patient population. SELLAS aims to leverage the partnership to accelerate enrollment, expand patient access to SLS009, and maintain cost efficiency, it added.The European study is expected to enroll 40 newly diagnosed AML patients with high-risk features to evaluate SLS009 in combination with azacitidine and venetoclax, medications to treat cancer. Enrollment at U.S. sites is planned to begin in the first quarter of 2026, with European enrollment anticipated in the second quarter of 2026, the company said.<h2 class="st-heading-2">Retail Chatter</h2>Despite the intraday decline, retail sentiment on Stocktwits remained in the ‘bullish’ zone over the past 24 hours, amid ‘high’ message volumes.<img src="https://news.stocktwits-cdn.com/SLS_jpg_8c87a5394f.webp" alt="SLS.jpg">One user saw the IMPACT-AML development as a positive for the stock and wondered why bears were still selling.<stembedurl>https://stocktwits.com/insidersruleloosersdrool/message/641795770</stembedurl>Another user said validating SLS009 in both the U.S. and the EU simultaneously makes the drug more attractive to a global buyer like Novartis.<stembedurl>https://stocktwits.com/Cresskill198/message/641779078</stembedurl>SLS shares have shot up 345% over the past 12 months.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/why-did-ibrx-stock-gain-retail-attention-today/cmULjP5R4eA">IBRX Stock Finds Retail Cheer After Company’s Immunotherapy For Bladder Cancer Gets Saudi FDA Approval</a> For updates and corrections, email newsroom[at]stocktwits[dot]com.

Representative image of stock price falling. (Photo by Yuichiro Chino/Getty Images)

SLS Stock In Spotlight On EU Expansion For Cancer Therapy – Retail Says Potential Catalyst For Buyout

The IMPACT-AML program will conduct a European clinical study evaluating SLS009 and provide SELLAS access to multiple clinical sites and a broader patient population.

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SELLAS Life Sciences Group (NASDAQ:SLS) Stock Price Up 10.3% - Here's What Happened

SELLAS Life Sciences Group (NASDAQ:SLS) Trading 10.3% Higher - Time to Buy...

SELLAS Life Sciences Group, Inc. is a clinical stage biopharmaceutical company, which engages in the development and commercialization of immunotherapeutic for cancer indications. Its product pipeline includes galinpepimut-S. The company was founded by Angelos M. Stergiou on April 3, 2006 and is headquartered in New York, NY.

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