Gilead Sciences Q1 Earnings Surpass Analyst Expectations, But Revenue Falls Short Of Estimates: Retail’s Optimistic

The company is eyeing FDA approval for its drug, lenacapavir, for HIV prevention by mid-June.

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In this photo illustration, the Gilead Sciences company logo is seen displayed on a smartphone screen. (Photo Illustration by Piotr Swat/SOPA Images/LightRocket via Getty Images)

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Anan Ashraf · Stocktwits

Published Apr 25, 2025, 12:41 PM

GILD

Shares of Gilead Sciences, Inc. (GILD) traded nearly 3% lower in pre-market on Friday after the company reported first-quarter (Q1) revenue below estimates.

The biopharmaceutical company on Thursday reported adjusted earnings per share (EPS) of $1.81 for the three months through the end of March, compared to a loss of $1.32 per share in the same period of 2024, and above an analyst estimate of $1.77.

Gilead pegged the increase in earnings to charges that did not repeat this year, including the impact of a $3.9 billion acquired in-process research and development expense related to the acquisition of CymaBay Therapeutics, Inc.

Total first quarter 2025 revenue of $6.7 billion remained flat and below an analyst estimate of $6.81 billion.

The company’s product sales fell 1% to $6.6 billion, following a 45% decrease in COVID-19 antiviral Veklury sales to $302 million.

Excluding Veklury, product sales increased 4% to $6.3 billion, owing to a 6% growth in HIV product sales and a 3% growth in sales from the company’s liver disease portfolio.

Sales of the company’s cancer drug Trodelvy, however, decreased 5% to $293 million owing to lower average realized price and inventory dynamics, the company said. Cell therapy product sales declined 3% to $464 million.

The company now expects product sales for the full year to be in the range of $28.2 billion to $28.6 billion, and adjusted EPS to be in the range of $7.70 to $8.10.

Gilead CEO Daniel O’Day said that the company had a “strong start to the year.” The firm is now looking forward to an FDA approval for its drug lenacapavir for HIV prevention by mid-June.

On Stocktwits, retail sentiment around GILD rose marginally in the ‘bullish’ territory over the past 24 hours, while message volume jumped from ‘normal’ to ‘extremely high’ levels.

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GILD's Sentiment Meter and Message Volume as of 8:15 a.m. ET on April 25, 2025 | Source: Stocktwits

GILD stock is up by about 16% year-to-date and by nearly 63% over the past 12 months.

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