Novartis Reportedly Eyeing To Acquire Avidity Biosciences: But Retail Expects Management To Sell Only At Significant Premium

Novartis has been evaluating a bid for Avidity and expressed interest in an acquisition in recent weeks, FT reported.

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In this photo illustration, the Novartis company logo is seen displayed on a smartphone screen. (Photo Illustration by Piotr Swat/SOPA Images/LightRocket via Getty Images)

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Anan Ashraf · Stocktwits

Published Aug 6, 2025, 4:49 PM

NVS

Novartis AG (NVS) has made a takeover approach for San Diego-headquartered Avidity Biosciences (RNA), Financial Times reported on Wednesday, citing people familiar with the matter.

Novartis has been evaluating a bid for Avidity and expressed interest in an acquisition in recent weeks, the report said. The discussions are at an early stage and might not result in a deal, sources told FT.

However, a takeover for Avidity would probably come with a premium, the people added.

Shares of Avidity were trading 22% higher at the time of writing.

On Stocktwits, retail sentiment around Avidity trended in the ‘extremely bullish’ territory over the past 24 hours, coupled with ‘high’ message volume.

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RNA's Sentiment Meter and Message Volume as of 12:23 a.m. ET on Aug. 6, 2025 | Source: Stocktwits


A Stocktwits user opined that they do not see the company management selling it for less than $70 or $80 per share, implying a significant premium to current price levels.  

Meanwhile, retail sentiment around Novartis jumped from ‘bearish’ to ‘neutral’ over 24 hours, accompanied by ‘normal’ levels of retail chatter.

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NVS's Sentiment Meter and Message Volume as of 12:23 a.m. ET on Aug. 6, 2025 | Source: Stocktwits


Avidity has three programs under development for three distinct rare diseases affecting the muscles: myotonic dystrophy type 1 (DM1), facioscapulohumeral muscular dystrophy (FSHD), and Duchenne Muscular Dystrophy (DMD).

Novartis, meanwhile, is looking to lose patent protection in the U.S. for some of its best-selling drugs, including heart failure drug Entresto and Xolair, used to treat several allergic conditions.

In February, Novartis also agreed to acquire Anthos Therapeutics, Inc., a Boston-based, privately held, clinical-stage biopharmaceutical company, for $925 million upfront.

While NYSE-listed shares of Novartis are up by 17% this year, RNA stock soared 60%. 

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