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Robinhood Markets, Inc is a financial services platform, which engages in the provision of retail brokerage and offers trading in U.S. listed stocks and Exchange Traded Funds, related options, and cryptocurrency trading, as well as cash management, which includes debit cards services. The company was founded by Vladimir Tenev and Baiju Prafulkumar Bhatt in 2013 and is headquartered in Menlo Park, CA.

Robinhood Markets Inc - Ordinary Shares - Class A

Robinhood Markets Inc

Robinhood (HOOD) is trending following a mixed earnings report that saw an EPS beat offset by a revenue miss, largely due to a decline in cryptocurrency trading. Community sentiment is polarized between concerns over valuation and crypto's impact, and optimism surrounding record annual performance, strong subscriber growth, new prediction markets, and a significant share buyback program.

Lyft, Inc. engages in the provision and management of an online social rideshare community platform. It offers access to a network of shared bikes and scooters for shorter rides and first mile and last-mile legs of multimodal trips, information about nearby public transit routes, and Lyft Rentals to offer riders a view of transportation options when planning any trip. The company was founded by Marcus Cohn, John Zimmer, Rajat Suri, Matt van Horn, and Logan Green in 2007 and is headquartered in San Francisco, CA.

Lyft Inc - Ordinary Shares Cls A

Lyft Inc

Lyft is trending following mixed quarterly earningsan EPS beat, largely attributed to a one-time tax benefit, contrasted with a revenue miss and soft guidancewhich led to a significant sell-off despite a new $1 billion share buyback. Community discussion is sharply polarized between those buying the dip on growth and future autonomous vehicle potential, and others emphasizing persistent competitive pressures and the increasing perceived threat of robotaxis.

Mattel, Inc. engages in the ownership of children's and family entertainment franchises. It operates through the following segments: North America, International, and American Girl. The North America and International segments focus on marketing and selling toys and consumer products. The American Girl segment includes marketing, retailing, and publishing dedicated to its mission to help girls grow up with confidence and character. The company was founded by Elliot Handler, Ruth Handler, and Harold Matson in 1945 and is headquartered in El Segundo, CA.

Mattel, Inc.

Mattel is experiencing a dramatic sell-off after missing Q4 earnings expectations and providing a weaker 2026 profit outlook, with the stock recently hitting a 52-week high before plummeting. The community is sharply divided, with many debating if the steep decline is an overreaction and looking to buy the dip, while others anticipate further downside.

Astera Labs, Inc. is a global semiconductor company, which engages in the provision of hardware and software solutions for AI and cloud infrastructure applications to solve data, memory, and networking bottlenecks. It operates through the following geographical segments: Taiwan, China, United States, and Other. The company was founded by Jitendra Mohan, Casey Morrison, and Sanjay Gajendra in October 2017 and headquartered in San Jose, CA.

Astera Labs Inc.

Astera Labs Inc

Astera Labs is trending as its recent Q4 earnings and Q1 guidance, while exceeding expectations, prompted a "sell the news" reaction, fueling community debate over its high valuation and characteristic volatility. Despite this, its integral role in AI infrastructure connectivity and a new warrant deal with Amazon tied to future purchases lead many to view the dip as a strategic buying opportunity.

Cloudflare, Inc. engages in the provision of cloud-based services to secure websites. It offers various products for performance and reliability, video streaming and delivery, advanced security, insights, Cloudflare for developers, domain registration, and Cloudflare marketplace. It operates through the United States and Rest of the World geographical segments. The company was founded by Matthew Prince, Michelle Zatlyn, and Lee Holloway in July 2009 and is headquartered in San Francisco, CA.

Cloudflare Inc - Ordinary Shares - Class A

Cloudflare Inc

Cloudflare is trending after its robust Q4 earnings and strong revenue guidance, which has spurred community discussion on its increasing importance as a core infrastructure provider for the "agentic internet" and AI workloads. Sentiment is highly positive, with many viewing the company as a top beneficiary in the AI era.

Upstart Holdings, Inc. engages in the provision of a cloud-based artificial intelligence lending platform. It operates through the following segments: Personal Lending, Auto Lending, and Other. The Personal Lending segment focuses on unsecured personal loans and small dollar loans. The Auto Lending segment is involved in auto refinance and auto retail loans. The Other segment refers to HELOCs and other. The company was founded by David Joseph Girouard, Anna Mongayt Counselman, and Paul Gu in December 2013 and is headquartered in San Mateo, CA.

Upstart Holdings Inc

Upstart is trending following its robust Q4 earnings report, which exceeded revenue and EPS expectations and included optimistic long-term growth targets and a planned CEO transition. While many investors are bullish on the AI lending platform's performance and potential for a short squeeze, the stock's tempered price reaction in a challenging fintech sector has fueled widespread market confusion and debate.

Moderna, Inc. engages in the development of transformative medicines based on messenger ribonucleic acid. The firm's product pipeline includes the following modalities: prophylactic vaccines, cancer vaccines, intratumoral immuno-oncology, localized regenerative therapeutics, systemic secreted therapeutics, inhaled pulmonary therapeutics and systemic intracellular therapeutics. It operates through the following geographical segments: United States, Europe, and Rest of World. The company was founded by Noubar B. Afeyan, Robert S. Langer, Jr., Derrick J. Rossi, and Kenneth R. Chien in 2010 and is headquartered in Cambridge, MA.

Moderna Inc

Moderna is trending due to groundbreaking five-year data from its personalized cancer vaccine trial with Merck, showcasing the potential of its mRNA platform in oncology; however, the stock faces significant volatility and community discussion following the FDA's refusal to review its influenza vaccine and ongoing patent litigation.

Ford Motor Co. engages in the manufacture, distribution, and sale of automobiles. It operates through the following segments: Ford Blue, Ford Model E, Ford Pro, Ford Next, Ford Credit, and Corporate Other. The Ford Blue, Ford Model E, and Ford Pro segment includes the sale of Ford and Lincoln vehicles, service parts, and accessories, together with the associated costs to develop, manufacture, distribute, and service the vehicles, parts, and accessories. The Ford Next segment is involved in the expenses and investments for emerging business initiatives aimed at creating value for Ford in vehicle-adjacent market segments. The Ford Credit segment consists of the Ford Credit business on a consolidated basis, which is primarily vehicle-related financing and leasing activities. The Corporate Other segment refers to corporate governance expenses, past service pension and OPEB income and expense, interest income and gains and losses from cash, cash equivalents, and marketable securities, and foreign exchange derivatives gains, and losses associated with intercompany lending. The company was founded by Henry Ford on June 16, 1903 and is headquartered in Dearborn, MI.

Ford Motor Co.

Ford Motor Co

Ford is trending after reporting weaker recent earnings and significant losses in its electric vehicle division, but strong future profit guidance and a strategic pivot to hybrids are driving positive investor sentiment and a perceived "margin-rebuild" narrative. This has sparked mixed community reactions and ongoing discussion around broader auto sector challenges with EV profitability.

Jumia Technologies AG engages in the provision of logistic services. It operates a pan-African e-commerce platform. It operates through the following geographical segments: West Africa, North Africa, East and South Africa, Europe, United Arab Emirates, and Others. The company was founded by Jeremy Hodara, Sacha Poignonnec, Peter Allerstorfer, Manuel Koser, Tunde Kehinde, and Raphael Afaedor in 2012 and is headquartered in Berlin, Germany.

Jumia Technologies Ag - ADR

Jumia Technologies is trending following its recent earnings report, which, despite showing strong revenue growth and significantly reduced cash burn, saw a "sell the news" reaction due to a larger-than-expected loss and a revised profitability timeline. The community is actively debating whether the sharp sell-off presents a buying opportunity, with bulls emphasizing improving fundamentals and bullish analyst coverage positioning Jumia as a key player in Africa's rapidly developing e-commerce market.

Novavax, Inc. Is a biotechnology company, which engages in the discovery, development, and commercialization of recombinant vaccines. The company was founded in 1987 and is headquartered in Gaithersburg, MD.

Novavax, Inc.

Novavax Inc

Novavax is trending as the community actively discusses how the FDA's refusal to review Moderna's influenza vaccine significantly enhances the market potential and value of Novavax's protein-based vaccine pipeline and its Matrix-M adjuvant technology. This fuels anticipation for new partnerships and intensified calls for management accountability amidst persistent short interest.

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LLY Expands Cell Therapy Ambitions With $2.4B Orna Therapeutics Deal

Eli Lilly is set to buy Orna Therapeutics for $2.4B to expand in vivo CAR-T and circular RNA capabilities, signaling a long-term push to diversify its pipeline.

Eli Lilly's 2025 Surge Sets the Stage for Another Big Year in 2026

LLY posts 45% revenue growth to $65.2B in 2025 as GLP-1 drugs power results, and guides $80-$83B in sales with EPS up over 40% in 2026.

INCY Q4 Earnings Miss Estimates, Revenues Beat on Higher Product Sales

Incyte posts a Q4 EPS miss but a 28% revenue jump, fueled by Jakafi and Opzelura strength, as product sales top estimates.

<ul class="summary-bullets"><li>GDNF outperformed semaglutide, the active ingredient in Wegovy and Ozempic, across several key measures, Hoth said.</li><li>The 12-week study showed that female mice on a high-fat diet experienced a 10% to 15% reduction in weight gain with GDNF, whereas semaglutide showed no meaningful effect.</li><li>The company said GDNF reduced liver weight by 20% to 30% and prevented fat buildup, highlighting its potential to address fatty liver disease.</li></ul>Hoth Therapeutics (HOTH), on Tuesday, announced preclinical results from a Veterans Administration-backed study evaluating glial cell-derived neurotrophic factor (GDNF) as a potential treatment for obesity and metabolic-associated steatotic liver disease (MASLD).The company stated that in a head-to-head comparison, GDNF outperformed semaglutide, the active ingredient in weight-loss drugs such as Wegovy and Ozempic, across several key measures, including weight control, glucose tolerance, liver weight reduction, and adipose tissue control.<a href="https://stocktwits.com/symbol/HOTH">HOTH shares</a> were up over 5% in pre-market trading but reversed gains after the opening bell, trading 6% lower.<h2 class="st-heading-2">What Did The 12-Week Study Show?</h2>During the 12-week study, female mice on a high-fat diet experienced a 10% to 15% reduction in weight gain with GDNF, eventually entering a stabilization phase, whereas semaglutide showed no meaningful effect. Researchers noted that higher doses or longer durations could amplify GDNF’s effects.GDNF also normalized fasting glucose levels and improved responses to glucose challenges. Additionally, the therapy reduced liver weight by 20% to 30% and prevented fat buildup, highlighting its potential to address fatty liver disease, a common issue with obesity.“These results are a monumental step forward for Hoth and the fight against obesity. GDNF not only matched but exceeded semaglutide in critical areas, opening doors to a new era of safer, more effective therapies,” said Robb Knie, CEO of Hoth Therapeutics.<h2 class="st-heading-2">What’s Next?</h2>Hoth plans additional studies on liver pathology, lipid content, and gene and protein expression to better understand GDNF’s mechanism, with clinical trials targeted for 2027.Weight-loss drugs have become a central focus for the pharmaceutical industry, driving revenue growth for leaders like Eli Lilly and Novo Nordisk as other companies race to enter the booming market.The segment has been under regulatory spotlight in the aftermath of Hims &amp; Hers launching a compounded version of Wegovy last week, which the company has since withdrawn following legal notices from NOVO and the U.S. Food and Drug Administration.&nbsp;&nbsp;<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment turned ‘bullish’ from ‘neutral’ a day earlier, accompanied by ‘high’ message volumes.<img src="https://news.stocktwits-cdn.com/HOTH_jpg_40deb046fb.webp" alt="HOTH.jpg">One user called for patience amid the intraday decline.<stembedurl>https://stocktwits.com/Tom678/message/644546402</stembedurl>HOTH shares are down around 21% so far this year.Read also: <a href="https://stocktwits.com/news-articles/equity/markets/why-did-azi-stock-reverse-gains-in-premarket/cZbUIHFR4Yy">AZI Stock Reverses Early Gains To Slump 30% In Pre-Market – What Happened?</a>For updates and corrections, email newsroom[at]stocktwits[dot]com

06 February 2025, Baden-Württemberg, Rottweil: A candlestick chart is opened in a trading platform on a smartphone. Photo: Silas Stein/dpa

Hoth Therapeutics' GDNF Treatment Shows Superior Efficacy Over Wegovy, Ozempic In Preclinical Trial

The company announced positive preclinical results from a study evaluating GDNF as a potential treatment for obesity and metabolic-associated steatotic liver disease.

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Wealthfront Advisers LLC Purchases 4,906 Shares of Eli Lilly and Company $LLY

Wealthfront Advisers LLC boosted its position in Eli Lilly and Company (NYSE:LLY - Free Report) by 4.6% in the 3rd quarter, according to its most recent filing with the Securities and Exchange...

Could Eli Lilly Turn Today's GLP 1 Obesity Boom Into Multi Decade, Millionaire Maker Gains?

Key PointsDemand for weight loss drugs is high, and analysts predict the market may reach nearly $100 billion in a few years...

Eli Lilly and Company (NYSE:LLY) Shares Down 1.2% - Time to Sell?

Eli Lilly and Company (NYSE:LLY) Stock Price Down 1.2% - Here's What Happened...

Novo Nordisk vs. Eli Lilly: What's the Better Long-Term Investment?

Key PointsEli Lilly has been a growth beast and its top line may soar by as much as 27% this year...

Promising Pharmaceutical Stocks To Watch Now - February 9th

Eli Lilly and Company, Novo Nordisk A/S, Pfizer, AbbVie, Abbott Laboratories, Gilead Sciences, and Bristol Myers Squibb are the seven Pharmaceutical stocks to watch today, according to MarketBeat's...

Best Medical Stocks To Watch Now - February 9th

Eli Lilly and Company, Hims & Hers Health, and Novo Nordisk A/S are the three Medical stocks to watch today, according to MarketBeat's stock screener tool. "Medical stocks" are shares of publicly...

Eli Lilly & Co. engages in the discovery, development, manufacture, and sale of pharmaceutical products. The firm's products consist of diabetes, oncology, immunology, neuroscience, and other products and therapies. The company was founded by Eli Lilly in May 1876 and is headquartered in Indianapolis, IN.

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