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Pyth Network is a decentralised oracle network designed to provide real-time financial market data to decentralised applications (dApps) across multiple blockchains. It allows developer to secure smart contracts with reliable, low-latency market data from institutional sources, and build apps with high-fidelity oracle feeds designed for mission-critical systems.

Pyth Network

Pyth Network is trending due to its selection by the U.S. Department of Commerce to distribute economic data on-chain, a move seen as a major step for decentralized infrastructure. The community is actively discussing potential price targets and the broader implications of government adoption of blockchain technology. Some users also believe that this could be the start of a long term hold.

Dog (Bitcoin) is a fully decentralized memecoin on the Bitcoin blockchain, backed by a community dedicated to onboarding millions of people to Bitcoin.  Dog is secured by the Bitcoin blockchain and exists on Bitcoin L1, marking a significant innovation compared to Bitcoin with just BTC. Dog is a Bitcoin Runes token with a minimal on-chain footprint, native to Bitcoin, and stored in UTXOs, just like Bitcoin.   What is the project about?  Dog does not do any paid promotion and is fully decentralized just like Bitcoin. Every influencer who chooses to post about Dog either received the airdrop or bought on secondary. Dog leverages the CC0 license to ensure that Dog is not owned by any single entity but rather by everyone. This had lead to the "DOG Army" independently creating art, apps, lotteries, plushies, websites, podcast, magazines, X account, IRL meetups, clothing lines, PFP collections, Telegram groups, and TikTok/Instagram about Dog.  What makes your project unique?  Dog was airdropped in the fairest memecoin launch ever. In early 2024, the Bitcoin Ordinals ecosystem came together in a full volunteer initiative that rewarded early adopters of the Ordinals Protocol. There was no team allocation, and 100% of the supply was airdropped for free. The airdrop algorithm favored neither whales nor influencers; it was determined by the community and made open-source for maximum transparency.

Dog (Bitcoin)

$DOG.X, a memecoin on the Bitcoin network, is trending as the community rallies around its fair distribution and potential to outperform other meme coins. Some believe it could become the leading meme on Bitcoin, citing its strong community and organic growth. The potential for listings on major exchanges and the backing of a publicly listed company, $CBLO, are also fueling interest.

Wrapped Centrifuge

Wrapped Centrifuge is gaining attention as community members actively discuss its potential breakout and encourage others to take a look. Some users point to news and increasing volume as potential catalysts, while others highlight its low supply. There's also discussion around the difference between $CFG.X and $WCFG.X.

Gyrodyne LLC engages in the management of a portfolio of medical office and industrial properties. Its properties include Flowerfield, Port Jefferson Professional Park, Courtland Medical Center, and Grove. The company was founded by Peter James Papadakos in 1946 and is headquartered in St. James, NY.

Gyrodyne LLC

GYRO is trending due to news of a major land sale, which the company projects will significantly boost its net asset value. The community is discussing the stock's low float and potential for a substantial breakout, drawing comparisons to other recent low-float runners. Some traders are closely watching key breakout levels, anticipating a rapid move upwards if these levels are breached.

WorldFinancial

World Financial (WLFI.X) is trending as traders discuss its potential value relative to its reserves and speculate on future price movements. The community is focused on the possibility of FOMO driving the price up, with some pointing to upcoming conferences and strategic directions as catalysts. Ongoing conversations also involve its association with political figures and the potential impact of regulatory developments.

StickyFam

StickyFam ($FAM.X) is trending as the community rallies around its potential, highlighting its growing follower base and recent listing on BingX. Comparisons to coins within the $DOGE.X and $SOL.X ecosystem are circulating, with many believing that $FAM.X is still early and poised for significant growth due to upcoming catalysts like CEX listings.

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$DOG is trending as the community discusses its potential as the 'DOGE of Bitcoin' and its fair, presale-free distribution. Bullish sentiment surrounds CBLO's increasing treasury holdings of DOG coins, with some anticipating ETF possibilities and tier 1 exchange listings. Conversation highlights $DOG's strong community and its activities within the Bitcoin ecosystem, particularly regarding Runestones and Ordinals.

Alcoa Corp. engages in the bauxite mining, alumina refining, and aluminum smelting and casting. It operates through the Alumina and Aluminum segments. The Alumina segment consists of a refining system, including the mining of bauxite, which is then refined into alumina, a compound of aluminum and oxygen that is the raw material used by smelters to produce aluminum metal. The Aluminum segment is composed of smelting and casthouse system. The company was founded by Charles Martin Hall on July 9, 1886 and is headquartered in Pittsburgh, PA.

Alcoa Corp

Alcoa ($AA) is trending as the community discusses its strong earnings report and potential benefits from tariffs, though some caution about potential headwinds. Bullish sentiment is fueled by analyst upgrades and a positive long-term outlook, while others are wary of short-term volatility. Community members are actively trading options, anticipating price movements based on the latest news.

Newmont Corp. engages in the exploration and acquisition of gold properties, containing copper, silver, lead, zinc or other metals. It operates through the following geographical segments: Canada, Mexico, Suriname, Argentina, Peru, Australia, Papua New Guinea, Ghana, and U.S. The company was founded by William Boyce Thompson on May 2, 1921 and is headquartered in Denver, CO.

Newmont Corp

Newmont Corp ($NEM) is trending as the price of gold reaches record highs, leading to speculation about boosted profits and potential buybacks. Community members are discussing recent Q2 earnings, a substantial buyback program, and the company's overall financial health, while others express concern about rising costs and potential overvaluation. Some investors view $NEM as a safe haven amid geopolitical tensions and economic uncertainty, while others anticipate a near-term pullback.

The Kraft Heinz Co. engages in the manufacture and market of food and beverage products. It operates through the North America and International geographical segments. The company was founded on July 2, 2015, and is headquartered in Pittsburgh, PA.

Kraft Heinz Co

Kraft Heinz is trending amid discussions around its plan to split into two separate companies by 2026, a move that has drawn skepticism from Warren Buffett, whose Berkshire Hathaway holds a significant stake. Community members are debating the potential impact of the spin-off on shareholder value and Berkshire's net income, with some questioning the strategic rationale behind the decision and its effect on the company's brands.

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Prothena (PRTA) Up 17.6% Since Last Earnings Report: Can It Continue?

Prothena (PRTA) reported earnings 30 days ago. What's next for the stock? We take a look at earnings estimates for some clues.

Shares of Prothena Corporation plc (PRTA) soared on Wednesday after Danish drugmaker Novo Nordisk (NVO) said that it expects to advance a drug developed by Prothena into a late-stage study for ATTR amyloidosis with cardiomyopathy.On Stocktwits, retail sentiment around Prothena jumped from ‘bearish’ to ‘bullish’ territory over the past 24 hours, while retail chatter rose from ‘normal’ to ‘high’ levels.<figure class="image"><img style="aspect-ratio:1332/122;" src="https://news.stocktwits-cdn.com/Screenshot_2025_08_06_at_1_09_34_PM_png_9facc97342.webp" alt="PRTA's Sentiment Meter and Message Volume as of 1:09 p.m. ET on Aug. 6, 2025 | Source: Stocktwits" width="1332" height="122"><figcaption>PRTA's Sentiment Meter and Message Volume as of 1:09 p.m. ET on Aug. 6, 2025 | Source: Stocktwits</figcaption></figure> A Stocktwits user expressed optimism for Prothena stock.<stembedurl>https://stocktwits.com/stocks271/message/623950128</stembedurl>Shares of Prothena traded 13% higher at the time of writing, while NYSE-listed shares of Novo traded 4% down.ATTR amyloidosis with cardiomyopathy (ATTR-CM) is a progressive and life-threatening disease where misfolded transthyretin (TTR) proteins deposit in the heart muscle, leading to heart failure. Prothena-developed Coramitug is designed to deplete the abnormal protein deposits.Coramitug was initially developed by Prothena and was acquired by Novo Nordisk in July 2021. During Novo’s earnings call on Wednesday, the company said that it has successfully completed a mid-stage study of the drug and will now initiate a late-stage study during the course of 2025. The company also said that it will share detailed data from the mid-stage study at a medical conference later this year.Under the terms of the agreement between Prothena and Novo Nordisk, the former company is eligible to receive up to $1.2 billion upon achievement of clinical development and sales milestones.Prothena is also eligible to earn a clinical milestone payment when prespecified enrollment criteria are met in the late-stage clinical trial. To date, Prothena has earned $100 million from the deal.PRTA stock is down by 43% this year and by about 61% over the past 12 months.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/novartis-reportedly-eyeing-to-acquire-avidity-biosciences/chrSPptRd5k">Novartis Reportedly Eyeing To Acquire Avidity Biosciences: But Retail Expects Management To Sell Only At Significant Premium</a>For updates and corrections, email newsroom[at]stocktwits[dot]com

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Novo Nordisk Commits To Advancing Prothena Corp-Developed Drug Into Late Stage Trial: Retail Turns Hopeful

Coramitug was initially developed by Prothena and was acquired by Novo Nordisk in July 2021.

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Coramitug was initially developed by Prothena and was acquired by Novo Nordisk in July 2021.


Prothena (PRTA) Reports Q2 Loss, Lags Revenue Estimates

Prothena (PRTA) delivered earnings and revenue surprises of -67.57% and -79.20%, respectively, for the quarter ended June 2025. Do the numbers hold clues to what lies ahead for the stock?

PTC Therapeutics (PTCT) Surges 11.2%: Is This an Indication of Further Gains?

PTC Therapeutics (PTCT) witnessed a jump in share price last session on above-average trading volume. The latest trend in earnings estimate revisions for the stock suggests that there could be more strength down the road.

Earnings Preview: Rhythm Pharmaceuticals, Inc. (RYTM) Q2 Earnings Expected to Decline

Rhythm Pharmaceuticals (RYTM) doesn't possess the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.

Roche Reports 7% 1H25 Sales Growth, Key Drugs Perform Well

RHHBY posts solid first-half 2025 growth on strong drug demand, but pipeline setbacks and biosimilar hits remain headwinds.

AstraZeneca's AL Amyloidosis Drug Misses Goal in Late-Stage Studies

AZN's anselamimab fails to meet key goals in late-stage AL amyloidosis trials despite signs of subgroup benefit.

PRTA Dives 53.5% YTD: Will the Restructuring Effort Boost Prospects? 

Prothena slashes 63% of its workforce and axes birtamimab after trial failure, reshaping its pipeline and financial outlook. Shares plunge 53.5% YTD. 

Prothena Corp shares climbed 5% in after-hours trading on Friday after the company said it expects to reduce its 2025 net cash burn from operating and investing activities to between $170 million and $178 million.&nbsp;The forecast follows a sweeping corporate restructuring that includes discontinuing development of birtamimab, an investigational therapy for AL amyloidosis, expected to reduce annual cash burn by about $96 million, and laying off 63% of its workforce.The biotech expects to end 2025 with roughly $298 million in cash, cash equivalents, and restricted cash at the midpoint.The revised cash burn outlook includes an estimated net loss of $240 million to $248 million, incorporating $36 million in non-cash share-based compensation and a $45 million non-cash tax expense related to deferred tax assets.The operating cost estimate includes $105 million to $110 million tied to birtamimab and reorganization-related expenses, such as severance and contract terminations.&nbsp;The company’s board and financial advisors are reviewing strategic options as it pivots to focus on its remaining pipeline and partnered programs.&nbsp;Prothena said it is reviewing strategic options as several clinical milestones approach, including Roche’s Phase 3 plans for prasinezumab in Parkinson’s, August data from Prothena’s PRX012 Alzheimer’s trial, and 2026 milestone payments of up to $105 million from partnered programs with Novo Nordisk and Bristol Myers Squibb.On Stocktwits, retail sentiment was ‘bullish’ amid ‘normal’ message volume.One user expressed confidence in Prothena’s prospects, indicating the stock may have substantial upside potential and encouraging a broader, long-term perspective on its trajectory.<stembedurl>https://stocktwits.com/alromofi777/message/618389231</stembedurl>Another user said the cost and workforce reductions were largely anticipated, adding they plan to sell if shares hold above $6 on Friday following the recent rebound from lows.<stembedurl>https://stocktwits.com/SQUEAKSBANDIT/message/618364635</stembedurl>The stock has declined 57.9% so far in 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

Prothena Shares Get A Boost After Company Slashes Workforce, Lowers 2025 Cash Burn Forecast

The biotech firm expects to end 2025 with nearly $300 million in cash as it pivots to focus on its Alzheimer’s and Parkinson’s pipeline.

RHHBY to Advance Parkinson's Disease Drug to Late-Stage Development 

Prothena Corp. Plc is a clinical-stage neuroscience company, which engages in the discovery and development of novel therapies to change the course of devastating diseases. The firm’s clinical pipeline includes both wholly owned and partnered programs being developed for the potential treatment of diseases including AL amyloidosis, ATTR amyloidosis, Alzheimer’s disease, Parkinson’s disease and other neurodegenerative diseases. The company was founded in December 1969 and is headquartered in Dublin, Ireland.

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