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NovoCure Ltd. is an oncology company which engages in the development, manufacture, and commercialization of Optune for the treatment of a variety of solid tumors. Its platform is called the Tumor Treating Field which uses electric fields tuned to specific frequencies to disrupt solid tumor cancer cell division. The company was founded by Yoram Palti in 2000 and is headquartered in St. Helier, Jersey.

NovoCure Ltd

NovoCure (NVCR) is trending due to the FDA approval of Optune Pax, the first new pancreatic cancer therapy in almost three decades, sparking significant community optimism for a major upward movement. However, some investors express skepticism regarding the therapy's perceived modest survival benefit and the potential for a sell-off by short sellers.

Viking Therapeutics, Inc. is a clinical-stage biopharmaceutical company, which engages in the development of therapies for metabolic and endocrine disorders. The company was founded by Brian Lian and Michael A. Dinerman on September 24, 2012 and is headquartered in San Diego, CA.

Viking Therapeutics Inc

Viking Therapeutics is a top trend after announcing its oral obesity drug will advance directly to Phase 3 trials following positive FDA feedback, igniting community debate over a potential short squeeze and significant buyout prospects amidst a rapidly expanding GLP-1 market.

Game asset trading is massive but broken. It is dominated by fragmented platforms, high fees, and unsafe peer to peer deals.  Players who create value should own it. Ownership must be verifiable, transferable, and secure.  OVERTAKE introduces a smart contract based marketplace built for trustless trading, real ownership, and scalable player economies.

OVERTAKE

Avantis is the largest RWA perps DEX in DeFi, built on and backed by Base. Avantis allows users to trade crypto and real-world assets (RWAs), including FX, commodities, indices, and equities. Backed by Pantera and Coinbase, Avantis is the largest DEX on Base by volumes, and brings institutional-grade products to DeFi, letting users trade with up to 500x leverage in a transparent, permissionless environment.  Avantis is best known for launching zero-fee perpetuals (ZFP) — a first-of-its-kind primitive where traders only pay fees if they profit. They've also brought leveraged RWAs onchain. This has driven explosive growth: over $20B+ in cumulative volume and 15M+ run-rate revenues since Febrruary 2024.

Avantis

Avantis (AVNT CRYPTO) is trending following its listing on Robinhood and the launch of its AI trading bot, fueling intense community debate around its potential as Coinbase's top perp dex on the Base chain. Bulls are highlighting its low market cap and strong use case compared to rivals like ASTER and HYPE, while others voice frustration over past price action and concerns about transparency.

AppLovin Corp. engages in the development and operation of a mobile marketing platform. It offers AppDiscovery, MAX, Adjust, and SparkLabs. Its software-based platform caters to mobile application developers to improve the marketing and monetization of applications. The company was founded by Andrew Karam, John Krystynak, and Adam Foroughi in 2011 and is headquartered in Palo Alto, CA.

Applovin Corp - Ordinary Shares - Class A

Applovin Corp

AppLovin is surging as a short-seller retracted serious allegations of financial crimes, fueling community sentiment that the stock was unfairly suppressed and is poised for a significant rebound, especially with highly anticipated strong earnings expected to reinforce its AI-driven growth story.

Zcash is a privacy-focused cryptocurrency that uses trustless zero-knowledge proofs to enable fully encrypted transactions while maintaining blockchain transparency and security. It was the first cryptocurrency to implement zero-knowledge encryption for private peer-to-peer payments, addressing the fundamental privacy gap in traditional cryptocurrencies that expose transaction details publicly.   With a fixed supply of 21 million ZEC and a halving schedule similar to Bitcoin, Zcash allows users to prove transactions are valid without revealing sensitive information like wallet balances, transaction amounts, or participant identities, making it suitable for everyday payments, long-term savings, and cross-border money transfers where financial confidentiality matters.  The protocol operates on its own blockchain currently using Proof-of-Work consensus, though it's evolving toward Proof-of-Stake through the planned "Crosslink" upgrade to enhance security, scalability, and energy efficiency. Zcash employs trustless zero-knowledge proofs (Halo) within its Orchard shielded pool to verify transactions without revealing sender, receiver, or amount information.   Users can choose between transparent public transactions and shielded private transactions through Unified Addresses, which work with both types. The network is faster and cheaper than Bitcoin, with new blocks mined every 75 seconds and transaction fees typically just a fraction of a cent. Privacy adoption has surged in 2025, with over 30% of total ZEC supply now held in fully shielded pools.  Zcash was created by a group of scientists in 2013 who initially proposed Zerocoin as a privacy extension to Bitcoin before building a standalone protocol. The ecosystem operates with a self-funded development model where block rewards support independent teams through the Zcash Community Grants Committee and a new Coinholder-Controlled Fund.

Zcash

Zcash is the subject of active community discussion following clarifying news that its core developers have formed a new startup, CashZ, to accelerate protocol scaling, a move initially misinterpreted but now largely seen as a bullish catalyst for ZEC's privacy features, further bolstered by recent positive regulatory clarity from the SEC.

Unity Software, Inc. engages in the developing video gaming software. It also provides software solutions to create, run and monetize interactive, real-time two-dimensional and three-dimensional content for mobile phones, tablets, consoles, and augmented and virtual reality devices. Its platform is used by developers, artists, and designers to build content for gaming, film, retail, automotive, architecture, engineering, and construction industries. The company was founded by Joachim Ante and David Helgason in 2004 and is headquartered in San Francisco, CA.

Unity Software Inc

Unity Software Inc. ($U) is trending following its Q4 earnings report, where it beat revenue and EPS estimates but provided weaker-than-expected Q1 guidance, leading to a significant stock sell-off. The community is divided between those who believe the plunge is an overreaction and a buying opportunity, and others who remain bearish due to AI competition fears and concerns over future profitability.

Shopify, Inc. is a global commerce company that provides essential internet infrastructure for commerce, offering trusted tools to start, scale, market, and run a retail business of any size. The Company's software enables merchants to run their business across all of their sales channels, including web and mobile storefronts, physical retail locations, social media storefronts and marketplaces. The Shopify platform provides merchants with a single view of their business across all of their sales channels and enables them to manage products and inventory, process orders and payments, fulfill and ship orders, build customer relationships, source products, leverage analytics and reporting and access financing, all from one integrated back office. The company was founded on September 28, 2004 and is headquartered in Ottawa, Canada.

Shopify Inc - Ordinary Shares - Class A (Sub Voting)

Shopify Inc

Shopify is trending after its strong Q4 revenue growth and a new $2 billion share buyback program were met with a volatile stock pullback, which many in the community are actively buying as an overreaction to minor concerns about guidance and AI impact.

SSgA Active Trust - State Street Consumer Discretionary Select Sector SPDR ETF

Consumer Discretionary Select Sector SPDR Fund

The Consumer Discretionary Select Sector SPDR Fund (XLY) is trending as investors grapple with a bifurcated consumer outlook, influenced by mixed retail spending data and evolving interest rate expectations. While some observe resilient spending, especially among higher-income households, broader community discussion emphasizes concerns about persistent inflation and the ongoing impact of tariffs, with the ETF's performance heavily reliant on major components like Tesla and Amazon navigating their own unique challenges.

Salesforce, Inc. engages in the design and development of cloud-based enterprise software for customer relationship management. Its solutions include sales force automation, customer service and support, marketing automation, digital commerce, community management, collaboration, industry-specific solutions, and salesforce platform. The firm also provides guidance, support, training, and advisory services. The company was founded by Marc Russell Benioff and Parker Harris in 1999 and is headquartered in San Francisco, CA.

Salesforce Inc

Salesforce is trending as widespread market fears regarding AI disruption of traditional enterprise software drive a significant sell-off, creating intense debate among investors over whether the stock is a "falling knife" or a deeply undervalued "generational dip buy."

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$HUBS please feel free to add to the DBAI (Death By AI) pronounced “DeBAI” not “DUBAI” — this is the software list so far $CRM $NOW n Hubs let’s put $SHOP IN THERE TOO just for fun.

JoeB

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HubSpot Inc

Adding $DUOL here. Another company about to be consumed by AI. List continues to grow. DUOL, CRM, PINS, ETSY, NOW, SHOP, HUBS, MNDY, PCOR, CHWY, $MSFT, $AI, ASAN, TEAM, DOCU, BILL, PATH.

Adding $DUOL here. Another company about to be consumed by AI. List continues to grow. CRM, PINS, ETSY, NOW, SHOP, HUBS, MNDY, PCOR, CHWY, MSFT,,,,,

$HUBS DUBAI lmao. Yes, DeBAI (Death By AI) is the correct term. Going to add the following to the list: $PINS $ETSY $BILL . Do your own DD. AI is destroying entire sectors. Please feel free to add to the list. Trying to save longs from the AI death wave....

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ServiceNow Inc

 please feel free to add to the DBAI (Death By AI) pronounced “DeBAI” not “DUBAI” — this is the software list so far 