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Rigetti Computing, Inc. provides full-stack quantum computing services. It serves global enterprise, government, and research clients through its Rigetti Quantum Cloud Services platform. The company was founded by Chad Rigetti in 2013 and is headquartered in Berkeley, CA.

Rigetti Computing Inc

RGTI is trending due to a mix of excitement and skepticism around its recent surge, with community members debating whether it's a legitimate rise or a potential bubble. The stock's connection to the quantum computing sector and AI, coupled with discussions about its valuation and revenue, are fueling the conversations. Some traders are pointing to potential short squeezes, while others are wary of a significant pullback.

Archer Aviation, Inc. engages in the development of electric vertical take-off and landing (eVTOL) aircraft. The company was founded by Brett Adcock and Adam Goldstein on October 16, 2018, and is headquartered in San Jose, CA.

Archer Aviation Inc - Ordinary Shares - Class A

Archer Aviation Inc

Archer Aviation is trending due to recent achievements and potential catalysts, including the registration of their Midnight aircraft with the FAA. Community members are actively discussing the company's prospects, particularly its relationship with Japan Airlines and potential military applications, while also debating whether the stock can outperform its competitor, Joby Aviation. Some investors believe upcoming events, like piloted VTOL flights and air shows, could trigger a significant price increase.

Luckin Coffee, Inc. engages in providing food and beverage items, and operates coffee retail stores. It has a pioneered a technology-driven retail network to provide coffee and other products of high quality, high convenience and high affordability to customers. The company manages pick-up stores, relax stores, and delivery kitchens. It also offers tea, snacks, and light meals through its mobile application. The company was founded by Zhi Ya Qian, Fei Yang and Jin Yi Guo on June 16, 2017 and is headquartered in Xiamen, China.

Luckin Coffee Inc - ADR

LKNCY is trending as investors celebrate the stock finally breaking the $40 mark, a level many have been watching for a long time, driven by expansion news. The community is expressing bullish sentiment, anticipating further growth and a potential Nasdaq relisting. Overall, the mood is optimistic as traders reflect on the company's journey and future potential.

Palantir Technologies, Inc. engages in the business of building and deploying software platforms that serve as the central operating systems for its customers. It operates through the Commercial and Government segments. The Commercial segment focuses on customers working in non-government industries. The Government segment is involved in providing services to customers that are the United States government and non-United States government agencies. Its platforms are widely used in areas such as defense, intelligence, healthcare, energy, and financial services, supporting data integration, large-scale analytics, and operational decision-making. The company was founded by Alexander Ceadmon Karp, Peter Andreas Thiel, Stephen Cohen, Joseph Lonsdale, and Nathan Dale Gettings in 2003 and is headquartered in Denver, CO.

Palantir Technologies Inc - Ordinary Shares - Class A

Palantir Technologies Inc

Palantir is trending due to a report of security flaws in a battlefield communications system, leading to a sharp intraday drop. While some investors are concerned about the implications of these vulnerabilities, others view the dip as a buying opportunity, citing the company's response that the issues have been addressed and the prototype nature of the system.

Alto Neuroscience, Inc. is a clinical-stage biopharmaceutical company, which engages in the development of psychiatric drugs. Its pipeline is composed of five clinical-stage assets which initially target depressive disorder and schizophrenia population. The company was founded by Amit Etkin, Dan Segal, and Wei Wu on March 25, 2019 and is headquartered in Mountain View, CA.

Alto Neuroscience Inc.

Alto Neuroscience ($ANRO) is trending as investors react to news of $IMG pulling its S-1 filing, eliminating concerns about potential dilution. The community is also buzzing about ANRO's expansion into crypto AI, including a $55M Bitcoin deal and a $20M fund with iZUMi. Bullish sentiment seems to be building amidst discussions of potential breakouts and short squeezes.

A project grown out of the community's love and passion for the weed culture. Launched around early 2025, $weedcoin, “Like Bitcoin but way higher,” emphasizes its alignment with cannabis culture and a laid-back vibe. Unlike other Weed communities, this project leans heavily into community engagement over technical utility, aiming to build a “stoner community” through social media presence and decentralized governance. We also aim to focus on onboarding web2 businesses and users onto web3 through the token.

Weedcoin

Weedcoin is trending as the community rallies around its vision, encapsulated by the phrase "Like Bitcoin But Way Higher". Active discussions involve the project's roadmap and potential, with community members emphasizing its cultural relevance and potential for growth, particularly regarding developments in the broader cannabis industry.

Richtech Robotics, Inc. engages in the development of robotic technologies. The firm designs, manufactures, and sells robots to restaurants, hotels, senior living centers, casinos, factories, and movie theaters. Its robots perform a variety of services including restaurant running and bussing, hotel room service delivery, floor scrubbing and vacuuming, and beverage and food preparation. The company was founded by Zhen Wu Huang and Zhen Qiang Huang on July 19, 2016 and is headquartered in Las Vegas, NV.

Richtech Robotics Inc. - Ordinary Shares - Class B

Richtech Robotics Inc.

Richtech Robotics ($RR) is trending with significant volume, fueled by community excitement and talk of a potential surge to new highs. Investors are actively discussing the company's potential to reach mid-cap status and the anticipation of news in October, while some reference a past short report as a catalyst for the stock's recent momentum. Discussion also includes comparisons to other robotics companies and speculation around the impact of robotics on the future.

Rumble, Inc. engages in operating an online neutral video platform. It operates through the following geographical segments: United States, Canada, and Other. The company was founded in October 2013 by Chris Pavlovski and is headquartered in Longboat Key, FL.

Rumble Inc - Ordinary Shares - Class A

Rumble Inc

Rumble ($RUM) is trending due to its strategic partnership with Perplexity AI, sparking discussions about enhanced content discovery and potential synergies within the AI space. The community is actively debating the impact of this partnership, especially given Rumble's existing ties to crypto through Tether and its potential to become a major cloud provider. High short interest is adding fuel to the fire, with many anticipating a significant short squeeze.

IonQ, Inc. develops and manufactures quantum computers. The firm specializes in quantum computing and quantum information processing. The company was founded by Christopher Monroe and Jung Sang Kim in 2015 and is headquartered in College Park, MD.

IonQ Inc

IONQ is trending due to community excitement around potential short squeezes and speculation about upcoming news, possibly related to government contracts, after a large after-hours buy. The community is actively discussing NVIDIA collaborations and the potential for the stock to reach new all-time highs, while also debating its valuation. Discussions also include perspectives on quantum computing's broader implications and contrasting viewpoints between bulls and bears.

Hims & Hers Health, Inc. operates a telehealth consultation platform. It connects consumers to healthcare professionals, enabling them to access medical care for mental health, sexual health, dermatology and primary care. The company was founded in 2017 and is headquartered in San Francisco, CA.

Hims & Hers Health Inc - Ordinary Shares - Class A

Hims & Hers Health Inc

Hims & Hers Health is trending as the stock experiences a significant sell-off, sparking debates among investors about potential causes, including a Bloomberg article referencing a competitor's GLP-1 product offering. The community is actively discussing whether the sell-off is an overreaction and if the company's fundamentals remain strong, while also eyeing potential bounce-back opportunities. Some traders speculate about algo manipulation and stop-loss triggers amidst the volatility.

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$AMRSQ One of the most precarious phases of large-scale fermentation is the biomass accumulation phase. This is when yeast are allowed to multiply to reach a high density of cells ready to commence synthesis. During this phase, some cells will develop mutations that allow them to escape synthesis, creating a fitness advantage. This advantage allows them to propagate more quickly than the other cells, overwhelming the population with mutant yeast cells that will not be productive (thereby destroying yield). 

The recent patent filing below reveals Amyris scientists found that if they introduced an “on/off switch”, which would suppress production until the switch is flipped, the strains were considerably more stable. One “switch” is oxygen sensitive, so that when a controlled amount of oxygen is introduced (micro aerobic conditions), synthesis will start. The other “switch” is the simple sugar maltose, which can be added after the accumulation phase is complete. 

https://patentscope.wipo.int/search/en/detail.jsf?docId=US304654671&amp;tab=PCTDESCRIPTION&amp;_cid=P20-KFBS1U-58832-1

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The present disclosure relates to the use of a switch for the production of heterologous non-catabolic compounds in microbial host cells. In one aspect, provided herein are genetically modified microorganisms that produce non-catabolic compounds more stably when serially cultured under aerobic conditions followed by microaerobic conditions, and methods of producing non-catabolic compounds by culturing the genetically modified microbes under such culture conditions.

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US20200270643 METHODS FOR STABILIZING PRODUCTION OF ACETYL-COENZYME A DERIVED COMPOUNDS

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Amyris Inc

$AMRS One of the most precarious phases of large-scale fermentation is the biomass accumulation phase. This is when yeast are allowed to multiply to reach a high density of cells ready to commence synthesis. During this phase, some cells will develop mutations that allow them to escape synthesis, creating a fitness advantage. This advantage allows them to propagate more quickly than the other cells, overwhelming the population with mutant yeast cells that will not be productive (thereby destroying yield). 

The recent patent filing below reveals Amyris scientists found that if they introduced an “on/off switch”, which would suppress production until the switch is flipped, the strains were considerably more stable. One “switch” is oxygen sensitive, so that when a controlled amount of oxygen is introduced (micro aerobic conditions), synthesis will start. The other “switch” is the simple sugar maltose, which can be added after the accumulation phase is complete. 



Wiffle1

@Wiffle1 

In your estimate, what are the implications of this advancement? Do you think it creates a moat that other synthbio firms will have to contend with? Or is this merely a natural progression that all leading synthbio firms will have to go through at some point?

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In your estimate, what are the implications of this advancement? Do you think it creates a moat that other synthbio firms will have to contend with? Or is this merely a natural progression that all leading synthbio firms will have to go through at some point?

@GreenAndGreen Great question. Anyone using organisms for synthesis from bacteria to yeast to mammalian cell lines uses a simple switch to control synthesis. The problem is that those simple switches are often “leaky”, which means you get some synthesis when you don’t want it - and that is where the mutational problems arise. 

What differentiates this patent is that they have tied synthesis to an additional on/off switch (on top of the standard/pre-existing one) dependent on oxygen, allowing for much tighter regulation and control. I’m not an expert in yeast, but this approach is pretty creative/novel, and their data suggests it has real implications for strain stability. The best part is that this approach can be applied to any industrial fermentation process, so it could affect their whole pipeline. So to answer your question, their moat is absolutely getting wider.

Ben M

T_Woo

Firegamerx

 Great question. Anyone using organisms for synthesis from bacteria to yeast to mammalian cell lines uses a simple switch to control synthesis. The problem is that those simple switches are often “leaky”, which means you get some synthesis when you don’t want it - and that is where the mutational problems arise. 

What differentiates this patent is that they have tied synthesis to an additional on/off switch (on top of the standard/pre-existing one) dependent on oxygen, allowing for much tighter regulation and control. I’m not an expert in yeast, but this approach is pretty creative/novel, and their data suggests it has real implications for strain stability. The best part is that this approach can be applied to any industrial fermentation process, so it could affect their whole pipeline. So to answer your question, their moat is absolutely getting wider.

@Wiffle1 thanks for the education. Really appreciate it.

 thanks for the education. Really appreciate it.

@Wiffle1 SIMPLY SUPERIOR, AND MOST USEFUL POST.  Thanks most kindly @Wiffle1

 SIMPLY SUPERIOR, AND MOST USEFUL POST.  Thanks most kindly 

@Wiffle1 No production manager wants to deal with this or dual end products (farnesene + carotenoids). Pie-in-the-sky.