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GRAIL, Inc. operates as a commercial-stage healthcare company, which engages in the development of a technology for early detection of cancer. It utilizes machine learning, software, and automation to detect and identify multiple deadly cancer types in earlier stages. The company was founded by Jeffrey T. Huber, William H. Rastetter, Mostafa Ronaghi, and Richard D. Klausner on September 11, 2015 and is headquartered in Menlo Park, CA.

GRAIL Inc.

GRAIL is experiencing extreme volatility following news that its flagship NHS-Galleri cancer screening trial missed its primary endpoint, despite beating Q4 revenue and EPS estimates. While some in the community see the massive price drop as an overreaction to misunderstood trial results, others are concerned about the long-term viability and potential for further decline.

Candel Therapeutics, Inc. is a clinical stage biotechnology company, which engages in the development and commercialization of viral immunotherapies. Its pipeline includes CAN-2409 and CAN-3110. The company was founded by Estuardo Aguilar-Cordova in 2002 and is headquartered in Needham, MA.

Candel Therapeutics Inc

Candel Therapeutics is trending following news of a proposed $100 million public stock offering and a $100 million royalty funding agreement, sparking intense community debate. While many shareholders express frustration over perceived dilution and management's strategy, supporters argue these moves are crucial to secure long-term financing and maintain independence for advancing its clinical pipeline toward potential commercialization.

Celsius Holdings, Inc. engages in the development, marketing, sale, and distribution of functional drinks and liquid supplements. It also offers post-workout functional energy drinks and protein bars. The company was founded in April 2004 and is headquartered in Boca Raton, FL.

Celsius Holdings Inc

Celsius is trending following recent positive comments from PepsiCo regarding its distribution partnership and Alani Nu integration, alongside a J.P. Morgan price target raise. The community is actively discussing the stock's growth potential and speculating on a possible PepsiCo acquisition, amidst ongoing concerns about stock price stability and management's communication leading into upcoming financial events.

Ardelyx, Inc. is a biopharmaceutical company, which engages in the business of developing and commercializing biopharmaceutical products. The firm is also involved in developing a unique and innovative platform that enables the discovery of new biological mechanisms and pathways to develop potent and efficacious therapies that minimize the side effects and drug-drug interactions frequently encountered with traditional, systemically absorbed medicines. The company was founded by Dominique Charmot, Peter G. Schultz, and Jean M. Frechet in October 2007 and is headquartered in Waltham, MA.

Ardelyx Inc

Ardelyx is trending amid community discussions regarding its latest Q4 earnings, which showed strong IBSRELA revenue growth offset by increased strategic investments, and recent news of a patent extension until 2042 for its key products. Additionally, investors are actively weighing the initiation of a new Phase 3 trial for IBSRELA and ongoing rumors of a potential acquisition by Zydus Lifesciences, with many expressing frustration over the stock's perceived undervaluation despite these developments.

Klarna Group Plc is a global digital bank and flexible payments provider. It operates through an AI-powered payments and commerce network that empowers people to pay smarter, with a mission to be available everywhere, for everything. The company was founded by Gustav Erik Niklas Adalberth, Karl Anders Victor Jacobsson, and Sebastian Marcin Siemiatkowski in 2005 and is headquartered in London, the United Kingdom.

Klarna Group plc

Klarna is trending following an earnings report that showcased robust revenue growth but also a net loss driven by increased credit loss provisions and an unclear path to profitability. This has polarized the community, with many calling the significant share price drop an overreaction to underlying growth, while others condemn the BNPL model as unsustainable amidst rising credit risks.

Newmont Corp. engages in the exploration and acquisition of gold properties, containing copper, silver, lead, zinc or other metals. It operates through the following geographical segments: Canada, Mexico, Suriname, Argentina, Peru, Australia, Papua New Guinea, Ghana, and U.S. The company was founded by William Boyce Thompson on May 2, 1921 and is headquartered in Denver, CO.

Newmont Corp

Newmont is trending after its Q4 earnings surpassed analyst expectations with strong revenue, EPS, and record free cash flow. However, investor sentiment is mixed, as many express frustration over the muted stock reaction, citing concerns about lower production guidance and higher projected costs for 2026.

AIOS Foundation

AIOS is trending following its recent ticker change from NISN, prompting renewed speculation among a divided community regarding its low float and potential as a "China penny play" amidst warnings of past dilution and upcoming offerings.

One Stop Systems, Inc. engages in the design, manufacture, and marketing of computing modules and systems targeting edge deployments. It deals with the design and manufacture of high-performance customized computer and flash arrays, in-flight entertainment, and connectivity and value-added reseller with minimal customization. It operates through the OSS and OSS Europe segments. The company was founded by Stephen D. Cooper and Mark Gunn in 1998 and is headquartered in Escondido, CA.

One Stop Systems Inc

One Stop Systems Inc. is actively trending due to significant government contract activity, with awards totaling over $65 million for the P-8A Poseidon aircraft program, alongside new commercial robotics deals, fueling community discussions around its growth trajectory and potential for substantial future contracts in the expanding Edge AI and defense sectors.

Atomera, Inc. engages in the development, commercialization, and licensing of proprietary processes and technologies for the semiconductor industry. It developed Mears Silicon Technology, which increases performance and power efficiency in semiconductor transistors. The company was founded by Robert Mears on November 26, 2001 and is headquartered in Los Gatos, CA.

Atomera Inc

Atomera (ATOM) is trending with significant volume as its Q4 earnings call details physical silicon results for MST in Nanosheet (GAA) architectures. This update, which hints at a potential 40% power reduction for AI chips crucial to data centers, is sparking community speculation about imminent licensing deals with major semiconductor players like TSMC and Samsung, despite ongoing concerns about its pre-revenue status.

Guardant Health, Inc. is a precision oncology company, which engages in the provision of treatment of cancer through the use of proprietary blood-based tests, vast data sets, and advanced analytics. Its solutions include treatment selection, recurrence detection, and early detection. The company was founded by Helmy Eltoukhy, AmirAli H. Talasaz, and Michael Joseph Wiley in December 2011 and is headquartered in Palo Alto, CA.

Guardant Health Inc

Guardant Health is generating significant buzz following robust preliminary Q4 and full year 2025 results, showcasing accelerating oncology growth and strong adoption of its Shield screening test. The community is highly optimistic about its potential, fueled by expanding insurance coverage like TRICARE and numerous analyst upgrades. This comes as the company continues to innovate in the precision oncology and liquid biopsy space.

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