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Applied Digital Corp. is a technology company, which engages in the provision of development and operation of data centers which provide computing power. It operates through the Data Center Hosting Business and HPC Hosting Business segments. The Data Center Hosting Business segment provides energized infrastructure services to crypto mining customers. The HPC Hosting Business segment focuses on the designing, constructing, and operating data centers tailored to support high power density applications like HPC and AI. The company was founded by Wesley Carl Cummins and Jason Zhang in May 2001 and is headquartered in Dallas, TX.

Applied Digital Corporation

Applied Digitals quarterly results and expansion outlook are driving attention, with traders highlighting a sharp revenue and adjusted-earnings beat, growing data-center capacity, and plans to bring more capacity online. The reaction is divided: bulls see strong execution and AI infrastructure demand, while skeptics point to the large GAAP loss, heavy debt, and tenant fit-out revenue mix; many are also debating why the stock response has been muted.

Webull Corp. engages in the provision of financial services. It offers trading, wealth management product distribution, market data and information, user community, and investor education. The company was founded by An Quan Wang in 2016 and is headquartered in St. Petersburg, FL.

Webull Corp. - Ordinary Shares - Class A

Webull Corp

A bipartisan House panels report alleging structural ties between Webull and China, including potential risks around U.S. customer data and funds, has triggered a sharp selloff in BULL. Webull disputes the findings as inaccurate; traders are split between viewing the drop as an overreaction and worrying about regulatory scrutiny and customer departures to rival brokers.

Robinhood Markets, Inc is a financial services platform, which engages in the provision of retail brokerage and offers trading in U.S. listed stocks and Exchange Traded Funds, related options, and cryptocurrency trading, as well as cash management, which includes debit cards services. The company was founded by Vladimir Tenev and Baiju Prafulkumar Bhatt in 2013 and is headquartered in Menlo Park, CA.

Robinhood Markets Inc - Ordinary Shares - Class A

Robinhood Markets Inc

Robinhoods offer to attract Webull customers is drawing attention after U.S. lawmakers raised concerns about Webulls China ties. Traders debate whether Robinhood can win users from the rival, with some seeing a share-taking opportunity and others criticizing the campaign and questioning whether customers will switch.

SELLAS Life Sciences Group, Inc. is a clinical stage biopharmaceutical company, which engages in the development and commercialization of immunotherapeutic for cancer indications. Its product pipeline includes galinpepimut-S. The company was founded by Angelos M. Stergiou on April 3, 2006 and is headquartered in New York, NY.

SELLAS Life Sciences Group Inc

SELLASs REGAL Phase 3 trial is drawing attention as traders await confirmation of the 80th survival event and final analysis. The extended wait has fueled speculation that GPS is helping patients live longer, but skeptics argue the control-arm treatment may also be producing unexpectedly durable survival; buyout rumors remain unconfirmed, and the silence is frustrating some investors.

Energy Fuels, Inc. is a mining development company, which engages in the exploration and evaluation of uranium and vanadium properties. It operates through the following segments: Uranium, Rare Earth Elements (REE), and Heavy Mineral Sands (HMS). The uranium segment engages in conventional and ISR uranium extraction, recovery and sales of uranium from mineral properties and the recycling of uranium-bearing materials generated by third parties along with the exploration, permitting and evaluation of uranium properties in the U.S. The REE segment is engaged in the company’s initiatives to progress towards full REE separation capabilities at the Mill to produce both light and heavy separated REE oxides in the coming years. The HMS segment engages in the exploration, development and recovery of HMS at the Kwale Project, Bahia Project, Vara Mada Project and the company’s equity method investments in the Donald Project JV and Tate. The company was founded by George E. L. Glasier and John David Mason on June 24, 1987 and is headquartered in Lakewood, CO.

Energy Fuels Inc

UUUU is drawing attention for its steep, persistent selloff and perceived underperformance versus uranium and rare-earth peers, fueling frustration and concerns about capital needs, dilution, and execution. Bulls counter that the long-term uranium and rare-earth strategyincluding the ASM acquisition and planned mine-to-magnet expansionremains intact, while some traders look for a technical rebound.

Wolfspeed, Inc. is an innovator of wide bandgap semiconductors, focused on silicon carbide and gallium nitride (GaN) materials and devices for power and radiofrequency (RF) applications. Its product families include silicon carbide and GaN materials, power devices and RF devices, and its products are targeted for various applications such as electric vehicles, fast charging, 5G, renewable energy and storage, and aerospace and defense. The company was founded by Calvin H. Carter Jr., John W. Palmour, F. Neal Hunter, Eric Hunter, and John Edmond in 1987 and is headquartered in Durham, NC.

Wolfspeed Inc - Ordinary Shares (New)

Wolfspeed Inc

Wolfspeeds conditional $1.5 billion, 30-year U.S. Department of War loan commitment to expand domestic silicon-carbide and gallium-nitride production is driving attention. Traders see potential financing support and a possible short squeeze, while others caution that the commitment is conditional and includes warrants that could dilute shareholders.

Liquidia Corp. operates as a holding company which engages through its subsidiary in developing and commercializing biopharmaceutical products and novel products development used in PRINT technology to transform the lives of patients. The company was founded in June 2004 and is headquartered in Morrisville, NC.

Liquidia Corp

A Delaware courts finding that Liquidias YUTREPIA infringes two United Therapeutics patent claims tied to the PH-ILD indication has driven intense debate over potential label changes, sales restrictions and damages as the parties seek a remedy. Traders are split between expecting further downside from the legal uncertainty and viewing the selloff as an opportunity, with an appeal or negotiated resolution still in focus.

Bitcoin is the world's first decentralized cryptocurrency, created in 2009 by the pseudonymous Satoshi Nakamoto. It enables peer-to-peer electronic cash transactions without intermediaries like banks or governments, operating on a blockchain secured by Proof of Work mining and the SHA-256 cryptographic algorithm.   With a fixed supply cap of 21 million coins and programmatic halvings every four years that reduce miner rewards, Bitcoin is designed as a deflationary digital asset often called "digital gold." Its value stems from solving the double-spending problem without trusted intermediaries, creating the first truly scarce digital asset with censorship resistance and permissionless access that no government, corporation, or individual can control.  Bitcoin operates as a decentralized peer-to-peer network where transactions are recorded on a public ledger called the blockchain, distributed across thousands of computers globally. Transactions are grouped into blocks added approximately every 10 minutes through mining, where specialized computers compete to solve complex mathematical puzzles.   Bitcoin has achieved mainstream adoption through multiple vectors. The January 2024 SEC approval of 11 spot Bitcoin ETFs opened Bitcoin investment to traditional finance participants, and corporations like Strategy (formerly MicroStrategy) are using Bitcoin as a treasury reserve asset to protect against currency debasement, offering MSTR holders amplified exposure to Bitcoin.   The Bitcoin ecosystem continues to evolve with innovations like Ordinals, which emerged in January 2023 to enable NFT-like functionality directly on Bitcoin, and BRC-20 tokens, an experimental standard for creating fungible tokens using Ordinal inscriptions. BTCFi (Bitcoin Finance) represents emerging financial applications extending beyond Bitcoin's traditional role, with protocols like Babylon allowing Bitcoin holders to stake BTC to secure Proof of Stake chains.

Bitcoin

Bitcoins pullback after failing to break through recent resistance has traders debating whether the weakness is a deeper breakdown or a routine correction. Bears point to soft price action and rising Treasury yields, while bulls view the dip as a buying opportunity and expect a rebound.

Johnson & Johnson is a holding company, which engages in the research, development, manufacture, and sale of products in the healthcare field. It operates through the Innovative Medicine and MedTech segments. The Innovative Medicine segment focuses on immunology, infectious diseases, neuroscience, oncology, cardiovascular and metabolism, and pulmonary hypertension. The MedTech segment includes a portfolio of products used in interventional solutions, orthopaedics, surgery, and vision categories. The company was founded by Robert Wood Johnson I, James Wood Johnson, and Edward Mead Johnson Sr. in 1887 and is headquartered in New Brunswick, NJ.

Johnson & Johnson

Speculation that J&J could acquire or partner with Sellas Life Sciences over its cancer-treatment candidate and pending REGAL trial dominates the discussion; traders point to executive connections and J&Js oncology ambitions, but no deal is confirmed and some urge caution. Others focus on J&Js rally, technical strength, and appeal as a defensive healthcare stock.

Pfizer Inc. is a research-based global biopharmaceutical company, which engages in the discovery, development, manufacture, marketing, sales and distribution of biopharmaceutical products worldwide. The firm works across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases. The company was founded by Charles Pfizer Sr. and Charles Erhart in 1849 and is headquartered in New York, NY.

Pfizer Inc.

Pfizer Inc

The FDAs approval of Pfizers Tukysa combination as a first-line maintenance treatment for HER2-positive metastatic breast cancer is drawing attention as an expansion of its oncology portfolio. Traders generally view the development positively, while some question whether it will provide enough momentum for a sustained share-price breakout.

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$SLS not sure if already posted, but here is PETHEMA registry data comparing VEN-based therapy with HMA monotherapy in AML. Figure S9 shows median survival and 3 yr survival comparisons for patients that reached CRc. Study link:

https://www.nature.com/articles/s41375-026-03154-3

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Client Challenge

$SLS What if we were to apply the Venetoclax mOS of 11.4 months (PETHEMA) to the REGAL study?
&quot;​Even if some patients in the control arm (Best Available Therapy / BAT) receive a Venetoclax-based combination, the 11.4-month mOS from the PETHEMA study cannot be applied to REGAL without a downward adjustment:
​Treatment-Naïve Baseline: PETHEMA’s 11.4-month mOS reflects newly diagnosed, untreated front-line AML patients.

​Prior HMA Exposure Limits Benefit: In PETHEMA, adding Venetoclax provided no statistically significant survival benefit to patients with prior HMA exposure (HR 0.78; non-significant).
​Relapsed / Refractory Setting: Because patients in second complete remission are pretreated and biologically selected for resistant disease, a Venetoclax regimen in the control arm would realistically yield an mOS in the 7 to 9-month range - well below the 11.4 months in first-line treatment.&quot; gemini AI

Here we are again: 7-9mOS BAT REGAL

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Ehrenhardt

$SLS This is great stuff. It lowers the upper boundaries on BAT therapies. Although this is not CR2, its findings support lower ceiling for BAT performance that for example I and the other BBQ doctors have brought up as possibilities. Thank you @Bazzil!

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 not sure if already posted, but here is PETHEMA registry data comparing VEN-based therapy with HMA monotherapy in AML. Figure S9 shows median survival and 3 yr survival comparisons for patients that reached CRc. Study link:

