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Bitcoin is the world's first decentralized cryptocurrency, created in 2009 by the pseudonymous Satoshi Nakamoto. It enables peer-to-peer electronic cash transactions without intermediaries like banks or governments, operating on a blockchain secured by Proof of Work mining and the SHA-256 cryptographic algorithm.   With a fixed supply cap of 21 million coins and programmatic halvings every four years that reduce miner rewards, Bitcoin is designed as a deflationary digital asset often called "digital gold." Its value stems from solving the double-spending problem without trusted intermediaries, creating the first truly scarce digital asset with censorship resistance and permissionless access that no government, corporation, or individual can control.  Bitcoin operates as a decentralized peer-to-peer network where transactions are recorded on a public ledger called the blockchain, distributed across thousands of computers globally. Transactions are grouped into blocks added approximately every 10 minutes through mining, where specialized computers compete to solve complex mathematical puzzles.   Bitcoin has achieved mainstream adoption through multiple vectors. The January 2024 SEC approval of 11 spot Bitcoin ETFs opened Bitcoin investment to traditional finance participants, and corporations like Strategy (formerly MicroStrategy) are using Bitcoin as a treasury reserve asset to protect against currency debasement, offering MSTR holders amplified exposure to Bitcoin.   The Bitcoin ecosystem continues to evolve with innovations like Ordinals, which emerged in January 2023 to enable NFT-like functionality directly on Bitcoin, and BRC-20 tokens, an experimental standard for creating fungible tokens using Ordinal inscriptions. BTCFi (Bitcoin Finance) represents emerging financial applications extending beyond Bitcoin's traditional role, with protocols like Babylon allowing Bitcoin holders to stake BTC to secure Proof of Stake chains.

Bitcoin

Bitcoin is trending amid a sharp market downturn and massive long liquidations, largely attributed to investor uncertainty following rumors of a hawkish Fed chair nomination. This has ignited a fierce debate in the community, with many bears calling it a "scam" while bulls advocate for buying the dip and point to ongoing market manipulation.

RAGE GUY (RAGE) is a cryptocurrency inspired by the Rage Guy meme, one of the earliest and most recognizable characters from internet rage comics. The project captures the cultural legacy of early meme history and brings it onto the blockchain in tokenized form. It is designed as a community-driven digital asset that celebrates internet culture, nostalgia, and the role memes play in shaping online communities.

Rage Guy

RAGE CRYPTO is trending due to its highly engaged community championing the "OG meme" narrative, positioning Rage Comics as a foundational reset for the current market cycle. The dedicated base demonstrates strong conviction, actively developing an ecosystem with platforms like RageMaker and RageGames, while urging enthusiasts to "Return to the Memes" and "Rage On" to establish dominance in the sector.

BlackRock Institutional Trust Company N.A. - iShares Silver Trust

iShares Silver Trust

A major disconnect between soaring Shanghai silver prices, indicative of relentless physical demand, and aggressive sell-offs in Western paper markets is fueling extreme volatility for SLV. The community is fiercely debating whether this reflects orchestrated suppression and impending scarcity or an overextended speculative bubble facing headwinds from rising margin requirements and potential copper substitution.

Apple, Inc. engages in the design, manufacture, and sale of smartphones, personal computers, tablets, wearables and accessories, and other varieties of related services. It operates through the following geographical segments: Americas, Europe, Greater China, Japan, and Rest of Asia Pacific. The Americas segment includes North and South America. The Europe segment consists of European countries, as well as India, the Middle East, and Africa. The Greater China segment comprises China, Hong Kong, and Taiwan. The Rest of Asia Pacific segment includes Australia and Asian countries. Its products and services include iPhone, Mac, iPad, AirPods, Apple TV, Apple Watch, Beats products, AppleCare, iCloud, digital content stores, streaming, and licensing services. The company was founded by Steven Paul Jobs, Ronald Gerald Wayne, and Stephen G. Wozniak in April 1976 and is headquartered in Cupertino, CA.

Apple Inc

Apple is trending following its record-breaking earnings report, which showcased significant growth in iPhone sales and services revenue, alongside optimistic Q2 guidance. Despite these strong results, much of the community expresses frustration over the stock's subdued price movement, with ongoing discussions centered on future margin pressures from rising memory costs and the company's AI collaboration strategy.

TechCreate Group Ltd. is a holding company, which engages in the provision of technology consultancy and software solutions. The firm also offers payment, cybersecurity, and digital services. Its business areas consist of professional services, software and maintenance licenses, and hardware solutions. The company was founded by Lim Heng Hai, Lau Kok Fong and Ronald Vong in 2015 and is headquartered in Singapore.

TechCreate Group Ltd. - Ordinary Shares - Class A

TechCreate Group Ltd. is experiencing a parabolic surge driven by a reported acquisition, leading to an astonishing price spike and fervent community discussion around a potential short squeeze. Traders are captivated by the extreme volatility and low-float dynamics, actively debating if this is a legitimate breakout or a speculative "pump and dump" following the company's statement of no material news.

Tesla, Inc. engages in the design, development, manufacture, and sale of electric vehicles and energy generation and storage systems. It operates through the Automotive and Energy Generation and Storage segments. The Automotive segment includes the design, development, manufacture, sale, and lease of electric vehicles as well as sales of automotive regulatory credits. The Energy Generation and Storage segment is involved in the design, manufacture, installation, sale, and lease of solar energy generation, energy storage products, and related services and sales of solar energy systems incentives. The company was founded by Jeffrey B. Straubel, Elon Reeve Musk, Martin Eberhard, and Marc Tarpenning on July 1, 2003 and is headquartered in Austin, TX.

Tesla Inc

Tesla is trending amid widespread speculation from Bloomberg and Reuters about a potential merger with SpaceX or xAI, following recent concerns over its automotive sales performance. The community is sharply divided, with bulls anticipating a massive, vertically integrated empire, while bears dismiss the talks as a desperate, dilutive maneuver to inflate share price.

Emergent BioSolutions Inc. engages in the development, manufacture, and commercialization of medical countermeasures. It operates through the following segments: Commercial Product Sales, MCM Product Sales, and Services. The Commercial Product Sales segment includes NARCAN products and other commercial products that were sold as part of the travel health business. The MCM Product Sales segment focuses on the Anthrax - MCM products, Smallpox - MCM products and other products. The Services segment consists of the company’s Bioservices offerings. It offers products for civilian and military populations that address accidental, intentional, and naturally occurring public health threats. The company was founded by Fuad El-Hibri on September 5, 1998 and is headquartered in Gaithersburg, MD.

Emergent Biosolutions Inc

Emergent BioSolutions is trending following an FDA approval for an OTC Narcan carrying case and a significant debt prepayment, with investors actively discussing potential for a substantial stock re-rating. While a recent lawsuit against its former CEO caused a dip, the community largely views it as non-material to the company's strengthening financial position and anticipated positive guidance.

Virtuix Holdings, Inc.is a technology and entertainment company. It focuses on developing virtual reality (VR) hardware and software. The company was founded by Jan Goetgeluk on December 20, 2013 and is headquartered in Austin, TX.

Virtuix Holdings Inc. - Ordinary Shares - Class A

Virtuix Holdings Inc. (VTIX) is trending due to extreme volatility following its recent market debut, with community members debating its potential for a massive short squeeze driven by a reportedly tiny float and significant year-over-year revenue growth, while others caution against a pump-and-dump scenario.

Hedera is a decentralized public network where developers can build secure, fair applications with near real-time consensus. The platform is owned and governed by a council of global innovators including Avery Dennison, Boeing, Deutsche Telekom, DLA Piper, FIS (WorldPay), Google, IBM, LG Electronics, Magalu, Nomura, Swirlds, Tata Communications, University College London (UCL), Wipro, and Zain Group.   The Hedera Consensus Service (HCS) acts as a trust layer for any application or permissioned network and allows for the creation of an immutable and verifiable log of messages. Application messages are submitted to the Hedera network for consensus, given a trusted timestamp, and fairly ordered. Use HCS to track assets across a supply chain, create auditable logs of events in an advertising platform, or even use it as a decentralized ordering service.

Hedera Hashgraph

Hedera (HBAR) is a focal point of intense community debate as it navigates significant market volatility, with bulls highlighting its growing enterprise partnerships, sponsorships at global economic forums, and compliance while skeptics point to its stagnant price action and low network revenue despite perceived catalysts. The broader crypto market sentiment and anticipation of regulatory clarity further fuel both optimistic accumulation and calls for caution.

Ethereum is a global, open-source platform for decentralized applications. In other words, it is a decentralized blockchain platform that enables developers to build and deploy smart contracts and applications without central authority control. Unlike Bitcoin, which primarily functions as digital currency, Ethereum operates as a programmable global computer where developers can create any type of decentralized service.   The platform hosts over $14 billion in DeFi applications with hundreds of thousands of active users across financial protocols, NFT marketplaces, and gaming platforms. Its transition to Proof of Stake in September 2022 reduced energy consumption by over 99%, addressing environmental concerns while strengthening network security.  The network operates through thousands of independent validator nodes that process transactions and execute smart contracts on the Ethereum Virtual Machine. Smart contracts are self-executing programs written in Solidity that automatically carry out agreements when conditions are met, eliminating intermediaries like banks or brokers.   Validators stake ETH as collateral to propose and validate blocks, earning rewards for honest participation while facing penalties for malicious behavior. The EIP-1559 upgrade introduced a dynamic base fee mechanism that burns ETH with each transaction, creating deflationary pressure during high network activity when more ETH is burned than issued to validators.  Vitalik Buterin proposed Ethereum in 2013, but seven co-founders helped build it, including Gavin Wood who created Solidity and the EVM technical specification, and Joseph Lubin who founded ConsenSys. The project launched in July 2015 after raising over $18 million through crowdfunding, quickly becoming the largest blockchain developer community. Major milestones include the 2020 Beacon Chain launch, the 2021 London hard fork implementing fee burning, and the 2022 Merge to Proof of Stake.   Ether (ETH) serves multiple functions: paying transaction fees (gas), staking to secure the network and earn 3-5% annual yields, serving as collateral in DeFi protocols, and purchasing NFTs and digital assets. The asset is increasingly adopted by traditional institutions, with publicly traded companies adding ETH to corporate treasuries to generate staking yields while maintaining blockchain exposure, and in 2024, the SEC approved spot Ethereum ETFs, allowing traditional investors to gain exposure through conventional brokerage accounts.  Ethereum's roadmap focuses on dramatically increasing transaction capacity to over 100,000 per second, reducing confirmation times, and enhancing decentralization while maintaining security against future threats like quantum computing.

Ethereum

Ethereum is trending due to heightened price volatility, with community members heavily discussing alleged market manipulation from exchanges like Binance, even as record staking inflows and progress on regulatory clarity continue to build its long-term fundamental case as a core utility for decentralized finance and AI.

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$CRNX $NBIX Consolidated View: 
 
Market is big enough for both.  
$NBIX = Standard of Care for the masses. 
$CRNX = The &#39;Heavy Lift&#39; for severe cases &amp; TARTs. 
 
Watch for &#39;Clinical Superiority&#39; designation for $CRNX to bypass orphan exclusivity. That is the key regulatory unlock. 
 
Read more: www.clinicaltrialsdaily.com/mc2r-antagonism-refractory-cah-potency/

Rick Glowaki

Alan Purdie

Phase 2 data indicates Atumelnant establishes a 'medical adrenalectomy' effect, significantly outperforming forthcoming standard of care in androgen suppression. See Disclaimer below * Unmet Medical Need and Epidemiology Congenital Adrenal Hyperplasia (CAH) represents a spectrum of enzymatic defects, predominantly 21-hydroxylase deficiency, leading to cortisol insufficiency and androgen excess.

Clinical Trials Daily

MC2R Antagonism vs. Upstream Modulation: Determining the Biochemical Ceiling in Refractory CAH

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Crinetics Pharmaceuticals Inc

Neurocrine Biosciences, Inc.

 Consolidated View: 
 
Market is big enough for both.  


 = The 'Heavy Lift' for severe cases & TARTs. 
 
Watch for 'Clinical Superiority' designation for 