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ImmunityBio, Inc. is a clinical stage immunotherapy company. It develops next generation therapies that drive immunogenic mechanisms for defeating cancers and infectious diseases. The company's immunotherapy platform activates both the innate and adaptive immune systems to create long term immunological memory. ImmunityBio was founded by Patrick Soon-Shiong in 2014 and is headquartered in San Diego, CA.

ImmunityBio Inc

The community is buzzing around ImmunityBio (IBRX) as founder Dr. Patrick Soon-Shiong appears in highly anticipated prime-time interviews to discuss breakthrough cancer treatments, with investors actively debating the potential for a significant short squeeze and an impactful business update next week that could challenge traditional pharma.

Applied Optoelectronics, Inc. engages in the design and manufacture of optical communications products. Its products include optical devices, such as laser diodes, photodiodes, related modules and circuitry, and equipment for applications in fiber-to-the-home, cable television, point to point communications, and wireless. The company was founded by Chih Hsiang Lin on February 28, 1997 and is headquartered in Sugar Land, TX.

Applied Optoelectronics Inc

Applied Optoelectronics is experiencing a massive surge following a significant earnings beat and upbeat guidance, fueled by robust demand for its 800G transceivers in AI data centers. This parabolic rally has ignited fervent community debate regarding its current extreme valuation and the potential impact of a recent at-the-market offering, amid broader sector enthusiasm for photonics.

Vanguard Group, Inc. - Vanguard Total Stock Market ETF

Vanguard Total Stock Market ETF

Vanguard Total Stock Market ETF ($VTI) is generating significant discussion as a bellwether for the U.S. market, with investors observing strong inflows and its proximity to all-time highs. The community is weighing these positive signals against prevailing political and economic uncertainties, prompting ongoing debate about diversification and market direction.

Eos Energy Enterprises, Inc. designs, manufactures, and deploys battery storage solutions for the electricity industry. It offers the Eos Znyth DC battery system product which designs to meet the requirements of the grid-scale energy storage market. The company was founded in 2008 and is headquartered in Edison, NJ.

Eos Energy Enterprises Inc - Ordinary Shares - Class A

Eos Energy is trending after a substantial earnings and revenue miss, coupled with weak 2026 guidance, has sent the stock plummeting, leading to widespread investor frustration and calls for management accountability. While many fear further downside due to perceived incompetence and potential dilution, a segment of the community views the steep decline as an overreaction, highlighting the company's growing backlog and role in the crucial energy storage market.

Hawaiian Electric Industries, Inc. is a holding company, which engages in electric utility and non-regulated renewable and sustainable infrastructure businesses. The company was founded by C. Dudley Pratt Jr. in 1981 and is headquartered in Honolulu, HI.

Hawaiian Electric Industries, Inc.

Hawaiian Electric is trending as investors assess recent earnings reports and ongoing legislative efforts to cap wildfire liabilities against concerns of significant share dilution and the substantial cost of its $1.99 billion settlement. The community is sharply divided between bulls anticipating a strong recovery fueled by institutional accumulation and bears warning of sustained selling pressure from future capital raises.

Aardvark Therapeutics, Inc. operates as a biotechnology company. It engages in the development of a novel, small-molecule therapeutics for the treatment of metabolic diseases. The company was founded by Tien Lee in 2017 and is headquartered in San Diego, CA.

Aardvark Therapeutics Inc.

Aardvark Therapeutics Inc

Aardvark Therapeutics is a top trending stock after voluntarily pausing its Phase 3 trial for ARD-101 due to cardiac safety signals, sparking widespread investor concern and negative sentiment around its pipeline and competitive position in Prader-Willi Syndrome treatment.

Soleno Therapeutics, Inc. operates as clinical-stage biopharmaceutical company, which engages in the development and commercialization of novel therapeutics for the treatment of rare diseases. It focuses on the treatment of metabolic and neurobehavioral disorder. It offers its lead candidate, Diazoxide Choline Controlled-Release (DCCR), an oral tablet for the treatment of Prader-Willi Syndrome (PWS). The company was founded on August 25, 1999 and is headquartered in Redwood City, CA.

Soleno Therapeutics Inc

Soleno Therapeutics is trending sharply following the FDA approval of VYKAT XR, the first therapy for Prader-Willi Syndrome, a catalyst amplified by competitor trial failures which is sparking intense community debate over its significant market potential and valuation amid ongoing short-seller challenges.

American Express Co. engages in the provision of card-issuing, merchant-acquiring, and card network businesses. Its products and services include credit cards, business credit cards, corporate programs, gift cards, savings accounts and CDs, and the American Express App. It operates through the following segments: the United States Consumer Services (USCS), Commercial Services (CS), International Card Services (ICS), Global Merchant and Network Services (GMNS), and Corporate and Other. The USCS segment includes proprietary consumer cards and provides services to United States consumers. The CS segment offers corporate and small business cards and provides services to United States businesses. The ICS segment provides consumers, small businesses, and corporate cards outside the United States. The GMNS segment is involved in operating a global payments network that processes and settles card transactions, acquires merchants, and provides multi-channel marketing programs and capabilities, services and data analytics. The Corporate and Other segment covers corporate functions and certain other businesses and operations. It also operates through the following geographical segments: United States, EMEA, APAC, LACC, and Other. The EMEA segment represents Europe, the Middle East, and Africa. The APAC segment refers to Asia Pacific, Australia, and New Zealand. The LACC segment focuses on Latin America, Canada, and the Caribbean. The Other segment includes net costs which are not directly allocated to specific geographic regions. The company was founded by Henry Wells, William G. Fargo, and John Warren Butterfield on March 28, 1850 and is headquartered in New York, NY.

American Express Co.

American Express is experiencing a sharp decline, alongside other financial stocks, due to widespread concerns that AI agents and stablecoins could fundamentally disrupt traditional payment networks by bypassing interchange fees, compounded by lingering discussions about proposed credit card interest rate caps. The community is actively debating the severity and plausibility of this "AI narrative" as a "structural shift," leading to both "buy the dip" sentiment and predictions of further downside in the sector.

Renaissance Capital Greenwich Funds - Renaissance IPO ETF

The IPO ETF is trending amidst a surge in new offerings, including a diverse range of SPACs, biotechs, and tech firms, sparking active community debate over mixed initial performance and potential market liquidity signals. While some recent debuts have seen significant pops, others have faced substantial deal size reductions, leading to a cautious yet active sentiment among investors.

SSgA Active Trust - State Street Health Care Select Sector SPDR ETF

Health Care Select Sector SPDR Fund

The Health Care Select Sector SPDR Fund ($XLV) is trending due to significant market rotation into defensive sectors amid broader market volatility, with many observing its strong performance and potential for a breakout to new highs. Simultaneously, President Trump's proposed 100% tariffs on branded pharmaceuticals are a major talking point, raising concerns about potential impacts on drugmakers and supply chains within the sector.

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Keefe, Bruyette &amp; Woods updates rating for Perella Weinberg ( $PWP ) to Market Perform, target set at 23 → 24.