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Bitcoin is the world's first decentralized cryptocurrency, created in 2009 by the pseudonymous Satoshi Nakamoto. It enables peer-to-peer electronic cash transactions without intermediaries like banks or governments, operating on a blockchain secured by Proof of Work mining and the SHA-256 cryptographic algorithm.   With a fixed supply cap of 21 million coins and programmatic halvings every four years that reduce miner rewards, Bitcoin is designed as a deflationary digital asset often called "digital gold." Its value stems from solving the double-spending problem without trusted intermediaries, creating the first truly scarce digital asset with censorship resistance and permissionless access that no government, corporation, or individual can control.  Bitcoin operates as a decentralized peer-to-peer network where transactions are recorded on a public ledger called the blockchain, distributed across thousands of computers globally. Transactions are grouped into blocks added approximately every 10 minutes through mining, where specialized computers compete to solve complex mathematical puzzles.   Bitcoin has achieved mainstream adoption through multiple vectors. The January 2024 SEC approval of 11 spot Bitcoin ETFs opened Bitcoin investment to traditional finance participants, and corporations like Strategy (formerly MicroStrategy) are using Bitcoin as a treasury reserve asset to protect against currency debasement, offering MSTR holders amplified exposure to Bitcoin.   The Bitcoin ecosystem continues to evolve with innovations like Ordinals, which emerged in January 2023 to enable NFT-like functionality directly on Bitcoin, and BRC-20 tokens, an experimental standard for creating fungible tokens using Ordinal inscriptions. BTCFi (Bitcoin Finance) represents emerging financial applications extending beyond Bitcoin's traditional role, with protocols like Babylon allowing Bitcoin holders to stake BTC to secure Proof of Stake chains.

Bitcoin

Bitcoin is experiencing a notable price decline, with the community largely attributing the drop to institutional selling and perceived market manipulation. This downturn is amplified by ongoing political uncertainties, including discussions around tariffs and potential government shutdowns. Sentiment is sharply divided, with some actively buying the dip while others express strong bearish outlooks and advocate for a shift to traditional safe-haven assets like gold and silver.

Ethereum is a global, open-source platform for decentralized applications. In other words, it is a decentralized blockchain platform that enables developers to build and deploy smart contracts and applications without central authority control. Unlike Bitcoin, which primarily functions as digital currency, Ethereum operates as a programmable global computer where developers can create any type of decentralized service.   The platform hosts over $14 billion in DeFi applications with hundreds of thousands of active users across financial protocols, NFT marketplaces, and gaming platforms. Its transition to Proof of Stake in September 2022 reduced energy consumption by over 99%, addressing environmental concerns while strengthening network security.  The network operates through thousands of independent validator nodes that process transactions and execute smart contracts on the Ethereum Virtual Machine. Smart contracts are self-executing programs written in Solidity that automatically carry out agreements when conditions are met, eliminating intermediaries like banks or brokers.   Validators stake ETH as collateral to propose and validate blocks, earning rewards for honest participation while facing penalties for malicious behavior. The EIP-1559 upgrade introduced a dynamic base fee mechanism that burns ETH with each transaction, creating deflationary pressure during high network activity when more ETH is burned than issued to validators.  Vitalik Buterin proposed Ethereum in 2013, but seven co-founders helped build it, including Gavin Wood who created Solidity and the EVM technical specification, and Joseph Lubin who founded ConsenSys. The project launched in July 2015 after raising over $18 million through crowdfunding, quickly becoming the largest blockchain developer community. Major milestones include the 2020 Beacon Chain launch, the 2021 London hard fork implementing fee burning, and the 2022 Merge to Proof of Stake.   Ether (ETH) serves multiple functions: paying transaction fees (gas), staking to secure the network and earn 3-5% annual yields, serving as collateral in DeFi protocols, and purchasing NFTs and digital assets. The asset is increasingly adopted by traditional institutions, with publicly traded companies adding ETH to corporate treasuries to generate staking yields while maintaining blockchain exposure, and in 2024, the SEC approved spot Ethereum ETFs, allowing traditional investors to gain exposure through conventional brokerage accounts.  Ethereum's roadmap focuses on dramatically increasing transaction capacity to over 100,000 per second, reducing confirmation times, and enhancing decentralization while maintaining security against future threats like quantum computing.

Ethereum

Ethereum is currently experiencing significant selling pressure and perceived manipulation, particularly during weekend trading, leading to widespread community frustration and calls of it being "trash." However, many are actively accumulating, viewing current dips as prime buying opportunities due to persistent institutional staking and anticipation of a forthcoming clarity act to provide regulatory certainty.

Hedera is a decentralized public network where developers can build secure, fair applications with near real-time consensus. The platform is owned and governed by a council of global innovators including Avery Dennison, Boeing, Deutsche Telekom, DLA Piper, FIS (WorldPay), Google, IBM, LG Electronics, Magalu, Nomura, Swirlds, Tata Communications, University College London (UCL), Wipro, and Zain Group.   The Hedera Consensus Service (HCS) acts as a trust layer for any application or permissioned network and allows for the creation of an immutable and verifiable log of messages. Application messages are submitted to the Hedera network for consensus, given a trusted timestamp, and fairly ordered. Use HCS to track assets across a supply chain, create auditable logs of events in an advertising platform, or even use it as a decentralized ordering service.

Hedera Hashgraph

Hedera (HBAR) is trending as the community debates its future, balancing significant institutional adoption and partnerships, such as its sponsorship of USA House at Davos, against persistent price underperformance. Enthusiasts see a "sleeping giant" accumulating at current levels for long-term growth and utility-driven appreciation, while skeptics express frustration over perceived dilution and stagnant value, intensifying calls for regulatory clarity to catalyze movement.

Dogecoin is a cryptocurrency based on the popular "Doge" Internet meme and features a Shiba Inu on its logo. Dogecoin is a Litecoin fork. Introduced as a "joke currency" on 6 December 2013, Dogecoin quickly developed its own online community and reached a capitalization of US$60 million in January 2014. Compared with other cryptocurrencies, Dogecoin had a fast initial coin production schedule: 100 billion coins were in circulation by mid-2015, with an additional 5.256 billion coins every year thereafter. As of 30 June 2015, the 100 billionth Dogecoin had been mined.   Dogecoin was created by Billy Markus from Portland, Oregon and  Jackson Palmer from Sydney, Australia. Both wanted to create a fun cryptocurrency that will appeal beyond the core Bitcoin audience. Dogecoin is primarily used as a tipping system on Reddit and Twitter where users tip each other for creating or sharing good content. The community is very active in organising fundraising activities for deserving causes.  The developers of Dogecoin haven’t made any major changes to the coin since 2015. This means that Dogecoin could get left behind and is why Shibas are leaving Dogecoin to join more advanced platforms like Ethereum. One of Dogecoin strengths is its relaxed and fun-loving community. However, this is also a weakness because other currencies are way more professional.  To purchase Dogecoin, it involves downloading a crypto wallet, setting up a crypto exchange account and then trading away for your desired crypto currency. Once we have set up an account with a DOGE currency exchange and deposited some funds, you are ready to start trading.

Dogecoin

Dogecoin is trending amidst significant price declines, with much of the community expressing frustration, labeling it a "scam" and blaming perceived abandonment by influential figures. Despite this strong bearish sentiment and predictions of further drops, a hopeful segment of holders continues to advocate for buying the dip and holding, pointing to various technical patterns as potential signals for an imminent rebound.

Bounce Token

Bounce Token (AUCTION) is drawing significant attention following a period of explosive price movement and a subsequent sharp correction, sparking widespread discussion within the crypto community. Many are debating its historical pattern of large pumps and the potential for a short squeeze, particularly after a recent, substantial reduction in its circulating supply. Enthusiasts are weighing its low supply and perceived undervaluation against its noted volatility and speculation around whale activity.

Solana is a high-performance Layer 1 blockchain designed for mass adoption by providing a fast, secure, and low-cost environment for decentralized applications. It distinguishes itself by scaling globally without the use of complex sharding or multiple layers, instead maintaining a single, unified ledger to avoid liquidity fragmentation. This architecture allows it to process thousands of transactions per second with sub-second finality, often at a cost of less than a penny per transaction.  The network operates on a unique hybrid model that combines Proof of Stake with an innovation called Proof of History, which functions as a decentralized clock to timestamp transactions. This system reduces the need for constant node communication, allowing the Sealevel engine to run non-conflicting smart contracts in parallel across multiple CPU cores. Further efficiency is gained through the Gulf Stream protocol, which reduces confirmation times by forwarding transactions to validators before the current block is finished.  Founded in 2017 by Anatoly Yakovenko, Solana is now supported by the Switzerland-based Solana Foundation and significant institutional investors like Andreessen Horowitz and Polychain Capital. The platform’s native token, SOL, serves as the primary currency for paying transaction fees, participating in network governance, and securing the system through staking.   Solana has also seen significant institutional adoption ranging from spot Solana ETFs to major partnerships including Visa's 2025 launch of USDC settlement on the network and the tokenization of public equity by firms like Galaxy Digital.

Solana

Solana is experiencing notable price volatility, driven by both market-wide crypto corrections and concerns over a lawsuit against the Solana Foundation. While many traders express extreme bearish sentiment, a significant portion of the community views current price levels as a strong accumulation opportunity, citing positive ETF inflows, robust network activity, and growing DeFi traction. This divergence highlights a battle between short-term market anxiety and confidence in Solana's long-term utility.

Dogelon Mars

Dogelon Mars ($ELON) is currently trending amidst intense community debate, with many investors expressing deep frustration over its prolonged decline and perceived failure to deliver on promises like a "Great Burn" or "Metaverse." While a segment of holders clings to hope for a future rebound, often referencing broader crypto "supercycle" narratives, the prevalent sentiment points to it as a 'dead coin' with developers accused of dumping supply. Discussions frequently highlight its inability to follow broader market rallies, contrasting its performance with other meme coins and major cryptocurrencies.

TransCode Therapeutics, Inc. engages in the development and commercializing of diagnostics and therapeutics for the detection and treatment of cancer. The company was founded by Robert Michael Dudley, Zdravka Medarova, and Anna Moore in January 2016 and is headquartered in Boston, MA.

TransCode Therapeutics Inc

TransCode Therapeutics is actively trending following a significant strategic financing, new leadership appointments, and an acquisition that expands its oncology pipeline. The community is discussing the potential for a substantial revaluation, driven by a low share float and the advancement of its lead TTX-MC138 asset towards Phase 2 trials, though some express caution regarding past shareholder dilution and the complex nature of recent corporate actions. Further clinical updates, including anticipated Phase 1a cancer trial data, are eagerly awaited as the company navigates the competitive biotech landscape.

Masonglory Ltd. is an investment holding company, which engages in the provision of wet trades and other related ancillary works. It offers plastering on floors, ceilings and walls, tile laying on internal and external walls and floors, brick laying, floor screeding, and marble works. The company was founded in 2018 and is headquartered in Hong Kong.

Masonglory Ltd.

Masonglory Limited

Masonglory Limited (MSGY) is generating buzz as an ultra low-float, high-volatility play, fueled by strong initial demand post-IPO over-allotment closing and reports of solid operational performance. The community is actively discussing potential for significant moves, citing high Cost to Borrow rates and historical rapid swings that have created notable opportunities for traders.

Aeluma, Inc. engages in developing semiconductors for sensing, communication, and computing applications. The firm is also involved in manufacturing devices using compound semiconductor materials on large-diameter substrates that are commonly used to manufacture mass market microelectronics. The company was founded by Jonathan Klamkin and Lee McCarthy on February 28, 2019 and is headquartered in Goleta, CA.

Aeluma Inc

Aeluma is trending, fueled by increased accessibility for investors as major brokerages lift trading restrictions on this low-float stock. The community is buzzing with excitement over Aeluma's proprietary monolithic integration of compound semiconductors onto large silicon wafers, which many believe is a game-changing technology. This innovation is positioned to revolutionize energy-efficient AI, quantum computing, and advanced sensing, promising significant commercial breakthroughs in high-growth sectors.

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ITC Ltd.

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$MNKD On the FDA tracker for PDUFA it has MNKD for May 29th (Afrezza-in-Children-and-Adolescent)and also July 26th (sNDA-of-FUROSCIX).  It does not show MNKD for Jan-April. 
https://www.fdatracker.com/fda-calendar/

Mike

kevinkleinheider

This calendar tracks upcoming PDUFA drug approval dates and FDA advisory committee meetings. Sign up or log in to access our Enhanced FDA Calendar! Our enhanced FDA calendar integrates PDUFA dates, clinical trial primary completion dates, and working capital runway estimates into a single timeline that covers companies publicly traded in the U.S.

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Mannkind Corp

 On the FDA tracker for PDUFA it has MNKD for May 29th (Afrezza-in-Children-and-Adolescent)and also July 26th (sNDA-of-FUROSCIX).  It does not show MNKD for Jan-April. 


Aeries Technology Inc. - Ordinary Shares - Class A

Netlist Inc

Plug Power Inc

Brazil Potash Corp

Smart Powerr Corp

Pulmonx Corp

Castellum Inc

John Williams

@inv4future 

So what?  PDUFA dates are only disclosed by the company.

You don’t really think that website is an official FDA website, do you? 😂   Wait, you do?

mr mulally

StockTwits for iOS

 

So what?  PDUFA dates are only disclosed by the company.

You don’t really think that website is an official FDA website, do you? 😂   Wait, you do?