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The market is focused on the expected interest rate decision, with community chatter split between anticipating a rally or a "sell the news" reaction. Many traders believe a 0.25% rate cut is already priced in, while others are closely watching Fed Chair Powell's commentary for further cues on the economic outlook and future monetary policy. Community members also discuss potential sector rotations and the impact of rate decisions on various asset classes.

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QQQ is trending as the market anticipates the Fed's rate decision, with widespread expectation of a 25 bps cut. Community members are closely watching Powell's tone and forward guidance, as well as potential sector rotations and the impact on small caps. Uncertainty surrounding inflation and labor market conditions adds to the speculation around the technology-heavy index.

Opendoor Technologies, Inc. engages in the operation of buying, selling, and trading of residential properties online. The company was founded by Eric Wu on December 30, 2013, and is headquartered in Tempe, AZ.

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Opendoor (OPEN) is trending amid discussions about the Federal Reserve's rate cut decision and its potential impact on the housing market; the community is debating whether the rate cut will stimulate growth or if it was already priced in. Some traders are pointing to the company's expansion plans as a catalyst, while others speculate about potential announcements from the CEO. Overall, the conversation revolves around the tug-of-war between bullish hopes for real estate and bearish concerns about market reactions.

Bitcoin is the first successful internet money based on peer-to-peer technology; whereby no central bank or authority is involved in the transaction and production of the Bitcoin currency. It was created by an anonymous individual/group under the name, Satoshi Nakamoto. The source code is available publicly as an open source project, anybody can look at it and be part of the developmental process.  Bitcoin is changing the way we see money as we speak. The idea was to produce a means of exchange, independent of any central authority, that could be transferred electronically in a secure, verifiable and immutable way. It is a decentralized peer-to-peer internet currency making mobile payment easy, very low transaction fees, protects your identity, and it works anywhere all the time with no central authority and banks.  Bitcoin is designed to have only 21 million BTC ever created, thus making it a deflationary currency. Bitcoin uses the SHA-256 hashing algorithm with an average transaction confirmation time of 10 minutes. Miners today are mining Bitcoin using ASIC chip dedicated to only mining Bitcoin, and the hash rate has shot up to peta hashes.  Being the first successful online cryptography currency, Bitcoin has inspired other alternative currencies such as Litecoin, Peercoin, Primecoin, and so on.  The cryptocurrency then took off with the innovation of the turing-complete smart contract by Ethereum which led to the development of other amazing projects such as EOS, Tron, and even crypto-collectibles such as CryptoKitties.

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Bitcoin is trending as investors anticipate the Fed's rate cut decision and its potential impact on crypto markets, with some expecting a bullish outcome and others bracing for a "sell the news" event. Community members are actively discussing potential price targets, the influence of rate cuts, and the performance of altcoins relative to Bitcoin. Broader discussions encompass Bitcoin's role as a store of value and its correlation with traditional markets.

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IWM is trending due to anticipation surrounding a potential Federal Reserve rate cut, with the market pricing in possible easing. Community discussions revolve around the impact of rate cuts on small-cap stocks and whether the expected news is already priced in, potentially leading to a "sell the news" event. Traders are closely watching for signals about the Fed's future policy and its effects on various sectors, especially small caps.

BigBear.ai Holdings, Inc. engages in data-driven decision dominance and advanced analytics that provide its customers with a competitive advantage in a world driven by data that is growing in terms of volume, variety, and velocity. The firm operationalizes artificial intelligence and machine learning at scale through its end-to-end data analytics platform. It deploys its observe, orient and dominate products to customers throughout the defense, intelligence, and commercial markets. The company was founded in 2020 and is headquartered in McLean, VA.

BigBear.ai Holdings Inc

BigBear.ai ($BBAI) is trending due to a combination of factors, including increased institutional buying from Goldman Sachs and a congresswoman's disclosed investment. The community is actively discussing the potential for a short squeeze and the impact of upcoming Fed decisions on the stock's momentum, as well as potential government contracts. Overall sentiment appears bullish, with many anticipating further gains and a breakout above key resistance levels.

Webull Corp. engages in the provision of financial services. It offers trading, wealth management product distribution, market data and information, user community, and investor education. The company was founded by An Quan Wang in 2016 and is headquartered in St. Petersburg, FL.

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Webull Corp

Conversations around Webull Corp (BULL) are focused on potential dilution and reverse splits, with some traders expressing frustration over the stock's performance despite broader market gains and upcoming rate cut decisions. Community sentiment is mixed, with some calling it a "garbage" stock and others anticipating a potential short squeeze or a move to higher price targets, especially with the potential of rate cuts. Some are drawing comparisons to similar companies, mentioning potential catalysts to be a breakout stock like competitors $HOOD and $SOFI.

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DIA is trending due to speculation around potential Fed rate cuts following weaker-than-expected jobs data, with the community debating whether this is a bull trap or a genuine signal for further market gains. Community members are closely watching upcoming inflation reports for further clues, while some express concern about the reliability of economic data. Debate continues about whether to "buy the dip" or prepare for a significant correction.

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TLT is trending as traders anticipate potential Fed rate cuts following recent economic data and await upcoming CPI and PPI reports, leading to discussions about recession risks and the bond market's next move. Community perspectives range from expectations of a bond rally to concerns about stagflation, with some highlighting the influence of tariffs and potential central bank actions. The conversation also involves analysis of technical indicators and potential trading strategies.

TOSHI

TOSHI.X is trending amid community excitement around new exchange listings, particularly in South Korea, and speculation about potential future listings on major platforms like Binance. Talk of a recent partnership with Coinbase is circulating, as well as anticipation surrounding potential interest rate cuts and their impact on the crypto market. The community is also actively discussing the coin's technical outlook and potential for significant gains.

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BioXcel Therapeutics, Inc. (BTAI) announced on Wednesday that its BXCL501 demonstrated continued effects and consistent benefit with repeat dosing in the treatment of agitation associated with bipolar disorders or schizophrenia in a late-stage trial.BXCL501 is an investigational, orally dissolving film formulation of Dexmedetomidine, marketed by the company as Igalmi. While the primary objective of the trial was to ascertain the safety of the formulation in an at-home setting, the continued effects and consistent benefits observed with repeat dosing in the trial further support the potential of BXCL501 for use in the outpatient setting, the company <a target="_blank" rel="noopener noreferrer nofollow" href="https://ir.bioxceltherapeutics.com/news-releases/news-release-details/bioxcel-therapeutics-reports-positive-topline-exploratory">said</a>.Shares of the company rose 3% in the pre-market session. On Stocktwits, retail sentiment around <a href="https://stocktwits.com/symbol/BTAI">BTAI stock</a> rose from ‘extremely bearish’ to ‘bearish’ territory over the past 24 hours, while message volume stayed at ‘extremely low’ levels.BioXcel <a href="https://stocktwits.com/news-articles/markets/equity/bioxcel-sublingual-film-well-tolerated-in-bipolar-schizophrenia-trial-in-at-home-settings/chsU5sURdl5">reported</a> late last month that the drug was well-tolerated in the study. The company said that the data from the study will form the basis of a submission to the U.S. Food and Drug Administration (FDA) slated for the first quarter of 2026 and aimed at expanding the label for Dexmedetomidine in the at-home setting.“These positive results, along with the safety and tolerability data previously announced, reinforce BXCL501’s potential in the at-home setting where there is substantial unmet need with no FDA-approved options currently available,” said BioXcel CEO Vimal Mehta.The company said that a total of 246 patients were part of the trial, and 2,437 agitation episodes in 208 patients were treated. All patients were able to successfully self-administer the film, and an average of 11.7 agitation episodes were recorded per treated patient.Igalmi is already approved for the acute treatment of agitation associated with bipolar I or II disorder or schizophrenia in medically supervised settings.BTAI stock is down by 40% this year and by 59% over the past 12 months.Read also:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/dow-futures-edge-lower-ahead-of-inflation-data/chwkJpfRduc">Dow Futures Edge Lower As Investors Turn Cautious Ahead Of Inflation Data: ORCL, KLAR, HOOD, GME Among Stocks To Watch</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

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BioXcel Stock Shoots Up 3% Pre-Market After Company Announces Positive Efficacy Data For Agitation Drug In Study

The company stated that the continued effects and consistent benefits observed with repeat dosing in the trial support the potential of BXCL501 for use in the outpatient setting. 

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BioXcel Therapeutics, Inc. (BTAI) on Wednesday said that its late-stage trial evaluating the safety of the company’s BXCL501 as a treatment for agitation associated with bipolar disorders or schizophrenia in the at-home setting met its primary goal of being well-tolerated.BXCL501 is an investigational, orally dissolving film formulation of Dexmedetomidine. The company <a target="_blank" rel="noopener noreferrer nofollow" href="https://ir.bioxceltherapeutics.com/news-releases/news-release-details/bioxcel-therapeutics-announces-serenity-home-pivotal-phase-3">said</a> that the data from the study will form the basis of a submission to the U.S. Food and Drug Administration slated for the first quarter of 2026 and aimed at expanding the label for its dexmedetomidine sublingual film called Igalmi in the at-home setting.Igalmi is already approved for the acute treatment of agitation associated with bipolar I or II disorder or schizophrenia in medically supervised settings.On Stocktwits, retail sentiment around <a href="https://stocktwits.com/symbol/BTAI">BTAI stock</a> jumped from ‘neutral’ to ‘bullish’ territory over the past 24 hours, while message volume rose from ‘low’ to ‘high’ levels.<figure class="image"><img style="aspect-ratio:624/65;" src="https://news.stocktwits-cdn.com/Screenshot_2025_08_27_at_9_42_20_AM_png_54402b6e8c.webp" alt="BTAI's Sentiment Meter and Message Volume as of 9:42 a.m. ET on Aug. 27, 2025 | Source: Stocktwits" width="624" height="65"><figcaption>BTAI's Sentiment Meter and Message Volume as of 9:42 a.m. ET on Aug. 27, 2025 | Source: Stocktwits</figcaption></figure>A Stocktwits user recommended buying the shares of the company.<stembedurl>https://stocktwits.com/Michael17711771/message/626688937</stembedurl>Another user opined that the study results are very promising long term.<stembedurl>https://stocktwits.com/They_call_me_tater_salad/message/626688733</stembedurl>BioXcel said that no discontinuations due to tolerability were observed in the arm of the study that received BXCL501.“By meeting its primary endpoint, the SERENITY At-Home Pivotal Phase 3 trial reinforces BXCL501’s potential to be safely used at home like it is already used in the previously FDA approved institutional setting. The unmet medical need in the at-home setting is significant with no FDA-approved treatments,” CEO Vimal Mehta said, while adding that the company believes the total addressable market is “significantly larger” than previously reported.The company said that a total of 246 patients were part of the trial, and 2,437 agitation episodes in 208 patients were treated. All patients were able to successfully self-administer the film, and an average of 11.7 agitation episodes were recorded per treated patient.The company said that available data demonstrate that treatment with BXCL501 regularly reduced symptoms of agitation throughout the trial. A greater percentage of patients experiencing mild, moderate, or severe agitation had full resolution of symptoms in the BXCL501 arm compared with placebo. Complete analyses of the full data set are ongoing and will be shared in time, the company said.BTAI stock is down by 24% this year and by 57% over the past 12 months.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/mannkind-united-therapeutics-expand-agreement-to-develop-second-investigational-molecule-together/chsURMTRdkC">MannKind, United Therapeutics Expand Agreement To Develop A Second Investigational Molecule Together</a>For updates and corrections, email newsroom[at]stocktwits[dot]com

Stock market down on a black background. | Image source: Yuichiro Chino via Getty Images

BioXcel’s Sublingual Film Well-Tolerated In Bipolar, Schizophrenia Trial In At-Home Settings, Retail Says Buy Now Or Regret Later

The company said that no discontinuations due to tolerability were observed in the arm of the study that received BXCL501.

BioXcel Therapeutics drew sharp retail-trader attention early Wednesday as the company gears up to release topline results later in the day for its experimental therapy to treat agitation linked to bipolar disorders and schizophrenia outside of clinical settings.The report from its SERENITY At-Home Phase 3 safety trial will reveal detailed effects of BXCL501, marketed as Igalmi, the company's sublingual film formulation of dexmedetomidine. The company plans to hold an investor call and webcast at 8 a.m. ET to discuss the data.The announcement about the release, made late Tuesday, triggered a 19% spike in&nbsp;<a href="https://stocktwits.com/symbol/BTAI">BioXcel's stock</a> after the bell, sending the ticker to the top of trending symbols on Stocktwits, accompanied by a 118% surge in 24-hour message volume. Sentiment, however, was ‘neutral’ as of the last reading.<figure class="image"><img style="aspect-ratio:1310/194;" src="https://news.stocktwits-cdn.com/BTAI_stock_sentiment_and_message_volume_on_Aug_27_png_6d08b1cb22.webp" alt="BTAI stock sentiment and message volume on Aug 27.png" width="1310" height="194"><figcaption>BTAI stock sentiment and message volume on Aug 27 as of 3:30 am ET | source: Stocktwits</figcaption></figure>Last week, BioXcel captured investors' attention after the company<a href="https://stocktwits.com/news-articles/markets/equity/bio-xcel-stock-in-focus-fda-issues-positive-early-feedback-ahead-of-key-meeting-on-expanded-psychiatric-label-1/chsOR5KRdQ1">&nbsp;said</a> the FDA had provided positive preliminary comments for Igalmi.The trial enrolled 200 patients living with bipolar disorder or schizophrenia who experienced agitation episodes despite being on stable treatment. Over 12 weeks, participants self-administered either 120 mcg of BXCL501, the same dose approved under medical supervision, or a placebo when symptoms arose.The trial tracked adverse events as its primary safety endpoint, while patients or caregivers also provided feedback using a modified global impression of severity scale.Igalmi is also being studied for agitation associated with Alzheimer's dementia, bipolar disorder, and schizophrenia in outpatient and at-home settings. It has received an FDA breakthrough therapy designation for agitation linked to dementia and a fast-track designation for agitation tied to schizophrenia, bipolar disorders, and dementia.BioXcel's stock short interest has also plunged since March, from over 10.6% to 1.8% as of the end of last week, according to Koyfin data.Shares of the company have shed nearly 15% this year.For updates and corrections, email newsroom[at]stocktwits[dot]com.Read Next:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/firefly-neuroscience-stock-scores-biggest-gain-in-weeks-on-nvidia-brain-platform-boost/chsxnkFRdkQ">Firefly Neuroscience Stock Scores Biggest Gain In Weeks On Nvidia Brain Platform Boost</a>

BioXcel's trial enrolled 200 patients living with bipolar disorder or schizophrenia who experienced agitation episodes despite being on stable treatment. | Representative image via Getty Images

BioXcel Sparks Retail Frenzy As Stock Soars Ahead Of Phase 3 Results For Bipolar, Schizophrenia Drug

Shares surged after hours on Tuesday, making BioXcel the most talked-about stock on Stocktwits, with message volume up 118% in the 24 hours following the announcement.

All Eyes On BioXcel Stock As Phase 3 Data For Bipolar, Schizophrenia Drug Due Today

Shares surged after hours on Tuesday, making BioXcel the most talked-about stock on Stocktwits, with message volume up 118% in the 24 hours following the announcement.


Retail chatter surged around BioXcel Therapeutics early Monday after the company said it received positive preliminary FDA comments ahead of an&nbsp;Aug. 20&nbsp;meeting to discuss expanding Igalmi’s label for at-home use in agitation tied to bipolar disorder and schizophrenia.The FDA’s remarks focused on aligning with the company over the format and content of the upcoming&nbsp;supplemental new drug application (sNDA)&nbsp;submission. BioXcel said it is evaluating the comments and expects to provide an update following the meeting.&nbsp;Currently, Igalmi is approved for hospital or supervised clinical use, and a green light for outpatient administration would open a new, significantly larger commercial opportunity.The regulatory update comes on the heels of BioXcel completing its Serenity At-Home Phase 3 trial earlier this month, with&nbsp;the&nbsp;last patient visits finalized across 22 U.S. sites.&nbsp;The pivotal study enrolled more than 200 patients and is designed to assess the safety of a 120 mcg self-administered dose of BXCL501 for acute agitation episodes in home settings. Top-line data are expected later this quarter and will form the backbone of the planned sNDA filing.The FDA has previously granted BXCL501 Breakthrough Therapy designation for dementia-related agitation and Fast Track status for schizophrenia, bipolar disorder, and dementia.&nbsp;BioXcel has also received two favorable recommendations from its Data Safety Monitoring Board, supporting the drug’s advancement toward regulatory review.Last Friday, H.C. Wainwright boosted its price target on the stock to $10 from $8 while sticking with a Buy rating, pointing to growing excitement around BXCL501.&nbsp;The brokerage firm called the upcoming Serenity trial readout “low-risk” and expects the company&nbsp;to&nbsp;file for an expanded label by the end of the year, with the FDA potentially signing off in the second half of 2026.On Aug. 6, BioXcel said a new paper in Frontiers in Pharmacology highlighted dexmedetomidine, the key ingredient in BXCL501.The study showed it could significantly influence stress-related behaviors in preclinical models, raising the possibility that the drug’s use might extend beyond calming acute agitation to helping manage longer-term psychiatric conditions.On Stocktwits, retail sentiment for BioXcel was described as ‘extremely bullish’ with ‘extremely high’ message volume, making it the platform’s most trending stock.One user urged that “$BTAI could be pushed over $50 this week” if investors “stick together,” adding that the community had the power to make it happen.&nbsp;<stembedurl>https://stocktwits.com/Eastcoasttrader11/message/625574895</stembedurl>Another user noted that if the Aug. 20 meeting went positively, it would signal that Phase 3 data had already come back strong as expected.<stembedurl>https://stocktwits.com/PejalPapa/message/625574210</stembedurl><a href="https://stocktwits.com/symbol/BTAI">BioXcel’s stock</a> has declined 8.4% so far in 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

Retail chatter surged around BioXcel Therapeutics (BTAI) early Monday after the company said it received positive preliminary FDA comments. (Photo credit: Getty Images)

BioXcel Stock In Focus: FDA Issues Positive Early Feedback Ahead Of Key Meeting On Expanded Psychiatric Label 

The update comes as the company wraps up its pivotal Serenity At-Home Phase 3 trial and analysts grow more optimistic on BXCL501’s commercial potential. 

BioXcel Therapeutics, Inc. (BTAI) Reports Q2 Loss, Lags Revenue Estimates

BioXcel Therapeutics (BTAI) delivered earnings and revenue surprises of -6.52% and -52.00%, respectively, for the quarter ended June 2025. Do the numbers hold clues to what lies ahead for the stock?

FDA Rejects CAPR's Cell Therapy BLA for Genetic Disorder, Stock Tanks

Capricor slumps 33% as the FDA rejects its BLA for DMD drug, deramiocel, citing lack of effectiveness data and CMC issues.

BioXcel Therapeutics' Approved Drug For Bipolar Disorders/Schizophrenia Shows No Evidence Of Worsening Or Withdrawal In Post-Marketing Study

BioXcel Therapeutics shares topline results from an Igalmi (dexmedetomidine) sublingual film study. The 180 mcg dose demonstrated favorable safety and efficacy in reducing agitation symptoms.
read...

Bioxcel Therapeutics: Navigating Financial Pressures and Clinical Trials   A Hold Rating Analysis

Mizuho Securities analyst Graig Suvannavejh has maintained their neutral stance on BTAI stock, giving a Hold rating on March 13. Graig Suvannavejh...

BioXcel Therapeutics Announces $25 Million Registered Direct Offering

NEW HAVEN, Conn., March 25, 2024 (GLOBE NEWSWIRE) -- BioXcel Therapeutics, Inc. (the Company ) (Nasdaq: BTAI), a biopharmaceutical company utilizing artificial intelligence approaches to develop...

Bioxcel Therapeutics Faces Market Estimation Risks Amidst Adoption and Access Challenges

Bioxcel Therapeutics (BTAI) has disclosed a new risk, in the Accounting & Financial Operations category. Bioxcel Therapeutics' projections of marke...

BioXcel Therapeutics, Inc. is a biopharmaceutical company, which engages in the development of artificial intelligence solutions in neuroscience and immuno-oncology. It also focuses on utilizing technology and research to develop therapeutics solutions. The company was founded by Vimal D. Mehta on March 29, 2017 and is headquartered in New Haven, CT.

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