RadioIsotope25
$CATX
It’s live. The abstract is 2396RO — not 2396O.
Key read-through:
67 patients treated as of April 3.
Efficacy set expands to 56 patients: 2 at 2.5 mCi, 46 at 5 mCi, 8 at 6 mCi.
They do not disclose the updated overall ORR for the 56-patient set in the abstract.
They restate the prior 5 mCi subset ORR: 43.4% (23/46).
In the 6 mCi cohort, 2 patients achieved PRs after one and two cycles.
Very clean safety: no DLTs, grade 4/5 AEs, treatment-related discontinuations, serious renal events, or clinically significant treatment-related myelosuppression.
Cohort 4 is enrolling.
So: good safety confirmation and no apparent bad surprise, but the abstract withholds the number everyone wants—the updated ORR. The Friday oral presentation should contain it.
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