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SPDR S&P 500 ETF Trust

Invesco QQQ Trust Series 1

Onyx is an infrastructure for a multi-asset, scalable, and cryptographically secure ledger. Onyx functions as a blockchain-based technology that enhances financial ecosystems by enabling a more efficient and interconnected economy, with a mission to develop cryptographic ledgers that optimize security, scalability, and usability. XCN is native to the Onyx XCN Ledger Blockchain as well as the Onyx Goliath Blockchain. XCN is also used as an ERC-20 token for Staking and Governance.

Onyxcoin

A sharp XCN price spike is drawing attention, with traders noting there is no clear news catalyst and debating whether the move is a short-lived pump-and-dump or a rebound worth buying. Some attribute broader weakness to Bitcoin and see the dip as an accumulation opportunity, while others question whether the token can hold its gains.

Papa John's International, Inc. engages in the operation and franchise of pizza delivery and carryout restaurants. It operates through the following segments: Domestic Company-owned Restaurants, North America Franchising, North America Commissaries, International Operations, and All Others. The Domestic Company-Owned Restaurants segment consists of retail sales of pizza and side items, breadsticks, cheese sticks, chicken poppers and wings, dessert items, and canned and bottled beverages. The North America Franchising segment involves the offering of sales and support activities, development rights, and collection of royalties from franchisees located in the United States and Canada. The North America Commissaries segment includes the eleven full-service regional dough production and distribution and quality control centers. The International Operations segment represents all restaurant operations outside of the United States and Canada. The All Others segment focuses on franchise contributions to marketing funds and sale, company-owned and franchised restaurants, information systems and related services used in restaurant operations, point-of-sale system, online and other technology-based ordering platforms, printing, and promotional items. The company was founded by John H. Schnatter in 1984 and is headquartered in Louisville, KY.

Papa John`s International, Inc.

Take-private speculation is driving attention, with traders discussing reported efforts by Irth Capital and Papa Johns largest U.S. franchisee to pursue a buyout. Many shareholders are urging a sale after the company rejected earlier offers, while others question whether a deal will materialize; no agreement is confirmed.

Amgen, Inc. is a biotechnology company, which engages in the discovery, development, manufacture, and marketing of human therapeutics. The company was founded by William K. Bowes, Jr., Franklin Pitcher Johnson, Jr., George B. Rathmann, and Joseph Rubinfeld on April 8, 1980 and is headquartered in Thousand Oaks, CA.

AMGEN Inc.

Positive Phase 3 results for Amgens IMDELLTRAImfinzi combination in first-line small-cell lung cancer are driving attention, with traders highlighting the survival benefit and potential to expand IMDELLTRAs role. The discussion centers on whether the cancer drug can become a meaningful growth driver alongside Repatha.

Agenus, Inc. is a clinical-stage company, which engages in the development and commercialization of technologies to treat cancers and infectious diseases. Its product pipeline includes Balstilimab, Zalifrelimab, AGEN1181, AGEN1327, AGEN2373, AGENt-797 and AGEN1777. The company was founded by Garo H. Armen and Pramod K. Srivastava on March 31, 1994 and is headquartered in Lexington, MA.

Agenus Inc

Agenus is drawing attention for an early Phase 2 BOT+BAL result reporting a 72% pathologic complete response rate in a dMMR colon cancer cohort after six weeks, with traders focused on the possibility of preserving organs and avoiding surgery. The reaction is optimistic but cautious: the community is waiting to see whether the response holds in later scans and proves durable.

Palo Alto Networks, is a cybersecurity company that provides cybersecurity platforms and services to enterprises, organizations, service providers, and government entities. Its offerings include network and AI security, cloud security, security operations, and identity security solutions. The company was founded by Nir Zuk in March 2005 and is headquartered in Santa Clara, CA.

Palo Alto Networks Inc

Palo Alto Networks is drawing attention after a sharp rebound alongside cybersecurity peers, as traders connect the sectors strength to AI-related security concerns, PHP2Shell vulnerability reports and indications that enterprise security budgets are firming. Bulls see stronger demand supporting the group, while skeptics argue that high valuations may already price in much of the opportunity.

Cloudflare, Inc. engages in the provision of cloud-based services to secure websites. The firm offers various products for application security, performance and reliability, network services, Zero Trust, developer platform, media delivery, insights, domain registration, and consumer services. It operates through the United States and Rest of the World geographical segments. The company was founded by Matthew Prince, Michelle Zatlyn, and Lee Holloway in July 2009 and is headquartered in San Francisco, CA.

Cloudflare Inc - Ordinary Shares - Class A

Cloudflare Inc

Cloudflare shares are drawing attention as a critical PHP vulnerability puts cybersecurity stocks in focus; traders see potential demand for Cloudflares web-application firewall and other protection services. The reaction is broadly bullish, though some posts frame the move as a short-term trade rather than a lasting shift.

Wormhole is a cross-chain messaging protocol that enables secure transfers of data or tokens across different blockchain networks. It supports a variety of applications, including DeFi, NFTs, and governance, by allowing data to be moved between blockchains efficiently and securely. Wormhole employs multiple verification methods to ensure the integrity and validity of the data transmitted through its network.

Wormhole

Traders are highlighting Wormholes reported integration with Ripple and the XRP Ledger as a potential boost to cross-chain adoption, alongside its role in tokenization and institutional projects. Bullish calls for a rebound and buying activity are countered by frustration over weak price action and concerns about token unlocks and selling pressure.

The GEO Group, Inc. engages in the design, financing, development, and support services for secure facilities, processing centers, and community re-entry facilities. It operates through the following segments: U.S. Secure, Electronic Monitoring and Supervision, Reentry, and International Services. The U.S. Secure Services segment encompasses the United States-based public-private partnership corrections and detention business. The Electronic Monitoring and Supervision Services segment conducts its services in the U.S. The Reentry Services Segment consists of various community-based and reentry services. The International Services segment consists of public-private partnership secure services operations in Australia and South Africa. The company was founded by George C. Zoley in 1984 and is headquartered in Boca Raton, FL.

Geo Group, Inc.

GEOs sale of detention facilities to DHS and related debt reduction are driving discussion, alongside expectations for further facility deals and expanded buybacks. Traders are divided over the stocks weakness despite the transactions, with some viewing the improved balance sheet as positive and others seeking clearer guidance on future sales, earnings, and political risks.

iShares Trust - iShares Biotechnology ETF

iShares Biotechnology ETF

A biotech-sector pullback after a recent run is the main focus, with IBB trading near its 50-day moving average. Traders are split between viewing the weakness as a pause and warning of broader sector pressure, while noting that larger biotech names have held up better than smaller ones.

PENN Entertainment, Inc. engages in the provision of integrated entertainment, sports content, and casino gaming services. It operates through the following business segments: Northeast, South, West, Midwest, Interactive, and Other. The Northeast segment includes Ameristar East Chicago, Hollywood Casino, Hollywood Gaming, Marquee, and Plainridge Park Casino operations. The South segment manages 1st Jackpot Casino, Ameristar Vicksburg, Boomtown, Hollywood Casino Gulf Coast, Hollywood Casino Tunica, L’Auberge, and Margaritaville Resort Casino. The West segment is involved in Ameristar Black Hawk, Cactus Petes and Horseshu, M Resort Spa Casino, and Zia Park Casino operations. The Midwest segment focuses on Ameristar Council Bluffs, Argosy Casino, Hollywood Casino, Prairie State Gaming, and River City Casino operations. The Interactive segment refers to an online gaming portfolio which includes ESPN BET, Hollywood Casino, theScore Bet, and PENN Game Studios. The Other segment consists of stand-alone racing operations, namely Sanford-Orlando Kennel Club, Sam Houston, and Valley Race Park. The company was founded by Peter M. Carlino in 1982 and is headquartered in Wyomissing, PA.

PENN Entertainment Inc

PENN Entertainment Inc.

PENNs steep selloff has traders focused on its upcoming quarterly report and whether the stock can stabilize, amid persistent concerns about digital-betting execution, profitability and management. Sentiment is divided between frustrated bears expecting further weakness and traders positioning for an oversold bounce ahead of earnings.

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12 Health Care Stocks Moving In Friday's Pre-Market Session

Gainers

Lucid Diagnostics (NASDAQ:LUCD) stock moved upwards by 29.7% to $0.42 during Friday's pre-market session. The company's market cap stands at $63.6 million.
Electra Therapeutics (NASDAQ:ETRA) stock roseread more...

Biotech Week Ahead: XLV Beats The Market — Here Are The Stocks, Readouts And Events To Watch Next 

Equity

Novo Nordisk (NVO) will hold its 2026 Capital Markets Day in London on Monday.

Electra Therapeutics, Inc. is a clinical stage biotechnology company. It is engaged in therapies against novel targets for diseases in immunology and cancer. The company was founded by Adam Rosenthal on October 11, 2018 and is headquartered in South San Francisco, CA.

Electra Therapeutics Inc

Neutral Sentiment

<ul class="summary-bullets"><li>The Health Care Select Sector SPDR Fund (XLV) gained 1.8% last week, outperforming the broader market and biotech ETFs.</li><li>Sellas Life Sciences (SLS) will present three preclinical SLS009 pancreatic-cancer studies at an AACR conference.</li><li>The Senate will hold a hearing Thursday on Heidi Overton’s nomination to lead the FDA.</li></ul><p>Biotech investors enter a catalyst-heavy week featuring Novo Nordisk’s strategy and pipeline update, Sellas Life Sciences’ SLS009 presentations, a Senate hearing on FDA leadership and at least two clinical updates still guided for the third quarter.</p><h2 class="st-heading-2"><strong>Healthcare Led The Market Last Week</strong></h2><p>The<a href="https://stocktwits.com/symbol/XLV">&nbsp;Health Care Select Sector SPDR Fund (XLV)</a> gained 1.8%, outperforming the broader market, while the<a href="https://stocktwits.com/symbol/QQQ">&nbsp;Invesco QQQ Trust (QQQ)</a> rose 0.9% and the<a href="https://stocktwits.com/symbol/SPY">&nbsp;SPDR S&amp;P 500 ETF Trust (SPY)</a> slipped 0.09%. The<a href="https://stocktwits.com/symbol/IBB">&nbsp;iShares Biotechnology ETF (IBB)</a> and<a href="https://stocktwits.com/symbol/XBI">&nbsp;SPDR S&amp;P Biotech ETF (XBI)</a> added 0.8% and 0.3%, respectively.</p><p><img src="https://news.stocktwits-cdn.com/healthcare_ef5dec4d7b.png" alt="healthcare.png"></p><h2 class="st-heading-2"><strong>This Week’s Biotech Catalyst Calendar&nbsp;</strong></h2><div><figure class="table"><table class="ck-table-resized"><colgroup><col><col><col></colgroup><tbody><tr><td>Date</td><td>Ticker/Event</td><td>Development</td></tr><tr><td>Sept. 21</td><td>NVO</td><td>Capital Markets Day in London</td></tr><tr><td>Sept. 21</td><td>ETRA</td><td>First full week of Nasdaq trading after its $350 million IPO</td></tr><tr><td>Sept. 24</td><td>FDA</td><td>Hearing on Heidi Overton’s nomination as FDA commissioner</td></tr><tr><td>Sept. 25-28</td><td>SLS</td><td>Three preclinical SLS009 posters at AACR’s pancreatic-cancer conference</td></tr><tr><td>By Sept. 30</td><td>SCYX</td><td>Potential Phase 1 results for intravenous SCY-247</td></tr><tr><td>By Sept. 30</td><td>QURE</td><td>Potential four-year Phase 1/2 update for AMT-130</td></tr></tbody></table></figure></div><h2 class="st-heading-2"><strong>Novo And Sellas Lead Scientific Calendar</strong></h2><p>Novo Nordisk (NVO) will hold its 2026 Capital Markets Day in London on Monday as it works to expand beyond the semaglutide franchise behind Ozempic and Wegovy. The event comes amid competition with Eli Lilly (LLY), which sells Mounjaro and Zepbound.</p><p>Novo recently adopted the shorter “Novo” brand while retaining Novo Nordisk as its legal name. CEO Mike Doustdar also introduced an updated “Novo Way” centered on customer obsession, competitiveness, clarity, and care and integrity. The company expects to launch CagriSema, its investigational cagrilintide-semaglutide combination, in 2027.</p><p>Sellas Life Sciences (SLS) will present three preclinical SLS009 posters at AACR’s pancreatic-cancer conference, which begins Friday in San Diego and runs through Sept. 28. SLS009 blocks CDK9, a protein that helps certain cancer cells survive and multiply. The research will examine its activity in laboratory models of KRAS-mutant pancreatic cancer, including combinations with BET and PARP inhibitors.&nbsp;</p><h2 class="st-heading-2"><strong>FDA Leadership And Q3 Readouts In Focus&nbsp;</strong></h2><p>The Senate Health, Education, Labor and Pensions Committee will hold a hearing Thursday on Heidi Overton’s nomination to lead the FDA. The FDA commissioner oversees reviews of drugs, vaccines, biologics and medical devices, along with policies governing clinical trials, manufacturing and post-market safety.&nbsp;</p><p>Scynexis (SCYX) has guided to third-quarter Phase 1 results for intravenous SCY-247 but has not set a release date. The experimental antifungal is being developed for invasive candidiasis and the prevention of invasive fungal disease.</p><p>UniQure (QURE) has separately guided to a four-year update from its Phase 1/2 AMT-130 study by quarter-end. The Huntington’s disease gene therapy can reduce production of the mutant huntingtin protein. The firm submitted its AMT-130 biologics license application earlier this month using three-year clinical data compared with an external control. The filing is complete, leaving the four-year update as the remaining quarter-end event.</p><h2 class="st-heading-2"><strong>Biotech IPO Pipeline Updates</strong></h2><p>Electra Therapeutics (ETRA) enters its first full week of trading after raising $350 million by selling 14 million shares at $25 each. The stock closed its Friday debut 12% below the IPO price. Electra’s pipeline is led by Veligrotug, an antibody for immune-related diseases.</p><p>Retension Pharmaceuticals and TRex Bio also filed for U.S. IPOs on Friday. Retension plans to list under RTSN and is developing cardiovascular drug RTN-001. TRex plans to trade under TRXB and is developing autoimmune and inflammatory-disease treatment TRB-061. Eli Lilly plans to invest in TRex alongside the offering.</p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com.</i></p><p>Read Next:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/tsla-stock-undervalued-analyst-roadster-barely-bull-case/cZMRTeURB47">TSLA Stock Looks ‘Slightly Undervalued’ To This Analyst — But The Roadster Is Barely Part Of The Bull Case&nbsp;</a></p>

SLS stock has surged 614% over the past year. (Photo credit: Getty Images)

Biotech Week Ahead: XLV Beats The Market — Here Are The Stocks, Readouts And Events To Watch Next

Electra Therapeautics

Lilly(Eli) & Co

Novo Nordisk A/S

uniQure NV

Scynexis Inc

SELLAS Life Sciences Group Inc

SPDR S&P Biotech ETF

Health Care Select Sector SPDR Fund

Up more than 1%

Flat to up 1%

Flat to down 1%

Down more than 1%

What do you think the S&amp;P 500&#39;s ($SPY) return will be next week?

Current Price	$8.71
Prev Close	$9.25
Open	$9.30
Dividend Yield	N/A
50-Day Moving Average	$10.46
Beta	0.00
Avg. Volume	1.03M
PE Ratio	N/A

52-Week High	$15.50
52-Week Low	$8.50
Market Capitalization	$546.7M
EPS (Annual)	-$0.9874
Price to Book	N/A
Revenue Per Employee	N/A

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