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SPY is experiencing extreme volatility driven by a conflicting narrative between a market-moving announcement from Donald Trump regarding a potential ceasefire with Iran and immediate, emphatic denials from Iranian state media. The community is sharply divided, with bulls cheering the prospect of de-escalation and potential liquidity injections, while bears and skeptics are accusing the administration of cynical market manipulation to stave off a broader sell-off.

SoFi Technologies, Inc. is a financial service platform, which engages in the provision of student loan refinancing options to the private student loan market. It operates through the following segments: Lending, Technology Platform, and Financial Services. The Lending segment offers personal loans, student loans, home loan products, and related servicing activities. The Technology Platform segment focuses on technology products and solutions revenue. The Financial Services segment includes the SoFi Money product, SoFi Invest product, SoFi Credit Card product, SoFi Relay personal finance management product, and other financial services. The company was founded in April 2011 and is headquartered in San Francisco, CA.

SoFi Technologies Inc

SoFi Technologies is experiencing significant volatility driven by a combination of broader macroeconomic headwinds, including rising oil prices and interest rate uncertainty, and a persistent, high-profile short report from Muddy Waters that has sparked intense debate over the company's accounting practices and growth sustainability. While some investors are bracing for further downside and expressing skepticism, a vocal segment of the community remains focused on CEO Anthony Noto's recent insider buying as a signal of long-term conviction and potential undervaluation.

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Aurinia Pharmaceuticals Inc

Aurinia Pharmaceuticals is at the center of significant investor enthusiasm following the removal of its CEO and key management team, signaling a major leadership overhaul that stakeholders hope will unlock shareholder value. The community is actively debating the potential for an imminent buyout or strategic sale, closely monitoring the influence of major shareholder Kevin Tang as they look for progress on the company's pipeline and patent negotiations.

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The United States Oil Fund is experiencing extreme volatility as market participants react to conflicting signals regarding the ongoing conflict with Iran, including unsubstantiated reports of imminent ceasefire talks and threats of further infrastructure strikes. Community discourse remains deeply divided between those betting on a prolonged supply crunch and those anticipating rapid de-escalation, all while traders adjust their positions to navigate the unpredictable impact of geopolitical headlines on crude prices.

Invesco QQQ Trust Series 1 - Invesco QQQ Trust Series 1

QQQ is experiencing intense volatility as investors react to conflicting headlines regarding potential ceasefire talks with Iran, with community sentiment split between skepticism over potential market manipulation and hopes for a de-escalation of regional tensions. Traders are actively debating the authenticity of administration statements versus official denials from Tehran, leading to sharp price swings as the market gauges the broader impact of geopolitical uncertainty on tech and energy stocks.

AleAnna, Inc. operates as a technology-driven energy company, which engages in supplying low-carbon natural gas and renewable natural gas to Italy. The company was founded in 2007 and is headquartered in Dallas, TX.

AleAnna Inc. - Ordinary Shares - Class A

AleAnna is trending due to a significant volume surge and investor interest driven by supply chain disruptions in the Middle East following infrastructure damage to major LNG facilities. The community is actively debating the stock's potential for further upward movement amidst geopolitical tensions, while keeping a close watch on technical support levels and the risk of volatility common in low-float energy plays.

DraftKings, Inc. is a digital sports entertainment and gaming company, which engages in the provision of online sports betting, online casino, daily fantasy sports product offerings, DraftKings Marketplace, retail sportsbook, media, and other consumer product offerings. The company was founded by Jason D. Robins, Matthew Kalish, and Paul Liberman on December 31, 2011 and is headquartered in Boston, MA.

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DraftKings is trending as investors react to a bipartisan Senate bill aimed at banning sports betting contracts on prediction markets like Polymarket and Kalshi. While community sentiment remains split on the stock's long-term volatility and management's handling of aggressive growth, many traders are closely watching the potential for the company to leverage its established sportsbook infrastructure against newer prediction market competitors.

Trump Media & Technology Group Corp. engages in operating social media and in the technology business. Its brands include TRUTH Social, TMTG+, and TMTG News. It operates through the Media and Truth.Fi segments. The Media segment includes products and services such as advertisement through the Truth Social platform. The Truth.Fi segment relates to customized exchange-traded funds or exchange-traded products invested in America First principles, and bitcoin and similar cryptocurrencies or crypto-related securities. The company was founded on March 28, 2024 and is headquartered in Sarasota, FL.

Trump Media & Technology Group Corp.

DJT is trending as investors react to high-stakes political maneuvering in the Middle East, with community discussion sharply divided over the potential for a market-moving deal versus concerns about escalating geopolitical risks. Traders remain hyper-focused on the stock's sensitivity to headline-driven volatility, fueling intense debate regarding its role as both a platform for discourse and a barometer for the current administration's market influence.

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iShares Russell 2000 ETF

The iShares Russell 2000 ETF (IWM) is trending as traders closely monitor geopolitical tensions in the Middle East and their impact on energy prices and broader market sentiment. The community is actively debating the reliability of ceasefire headlines, with many investors adjusting their portfolios to hedge against volatility while navigating conflicting signals regarding Fed rate policy.

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ProShares UltraShort Bloomberg Crude Oil (SCO) is attracting heavy volume as traders pivot to hedge against or bet against the recent volatility in crude oil prices driven by geopolitical tensions in the Strait of Hormuz. While some investors are scaling into the position expecting a eventual normalization in oil supply and a price correction, the community is actively debating the impact of the ETF's daily decay and the potential for rapid price swings as news regarding energy infrastructure and global strategic reserve releases continues to emerge.

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<ul class="summary-bullets"><li>The company had initially set January 20 as the effective date of the reverse stock split, but delayed the move following additional internal review.</li><li>The total outstanding shares have been reduced from about 6.39 million to roughly 1.02 million.</li><li>This is Psyence Biomedical’s second reverse stock split action in eight months, following a 1-for-7.97 split on May 5.</li></ul>Psyence Biomedical (PBM) stock was in the spotlight on Monday morning after its shares began trading on a post-reverse-split basis on the Nasdaq Capital Market on Monday.<a href="https://stocktwits.com/symbol/PBM">PBM shares</a> were up around 60% at the time of writing.The company had initially set January 20 as the effective date of its 1-for-6.25 reverse stock split, but delayed the move following additional internal review.Under the consolidation, each 6.25 existing share will be combined into one share, reducing the total outstanding shares from about 6.39 million to roughly 1.02 million. The reverse split was authorized by shareholders at a special meeting in April 2025, allowing the board to consolidate shares at a ratio of up to 1-for-50.<h2 class="st-heading-2">Second Reverse Split</h2>Following the special meeting, Psyence Biomedical had implemented a 1-for-7.97 split on May 5, 2025, to increase the per-share trading price of its shares to meet Nasdaq’s $1.00 minimum bid price requirement.Earlier this year, Psyence said its board approved a 2026 financial strategy that includes authorization for a potential share repurchase program to preserve capital for key clinical milestones. The company noted that its stock may be undervalued and that share repurchases could increase per-share ownership.Last November, Psyence approved a $3.5 million follow-on investment in PsyLabs, a producer of purified psychedelic active pharmaceutical ingredients. The investment secures PsyLabs’ position as a critical supplier of GMP-grade psilocybin and ibogaine, supporting Psyence’s clinical pipeline.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment for PBM on Stocktwits turned ‘extremely bullish’ from ‘bullish’ a session earlier, amid ‘high’ message volumes.<img src="https://news.stocktwits-cdn.com/PBM_jpg_50a47c9349.webp" alt="PBM.jpg">One Stocktwits user expects the stock to double in value.<stembedurl>https://stocktwits.com/johnny6nine/message/643661274</stembedurl>Read also: <a href="https://stocktwits.com/news-articles/markets/equity/why-is-hood-stock-falling-today/cZbgrOOR4kk">HOOD Stock Falls To Over 6-Month Lows – Piper Sandler Flags Three Near-Term Risks But Retail Sees Buying Opportunity</a> For updates and corrections, email newsroom[at]stocktwits[dot]com.

Wilmington, Delaware-based NRx Pharmaceuticals registered the biggest spike in retail message volume among healthcare stocks last week.  | Image source: Getty Images

Why Is PBM Stock Drawing So Much Investor Interest Today?

Psyence Biomedical was in the spotlight after its shares began trading on a post-reverse-split basis, following a 1-for-6.25 consolidation.

Equity

NEW YORK – December 9, 2025 – Psyence Biomedical Ltd. (Nasdaq: PBM) (“Psyence BioMed” or the “Company”), a biopharmaceutical company advancing nature-derived psilocybin and ibogaine therapies for unmet mental health needs, <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://psyencebiomed.com/ceo-year-end-letter-to-shareholders">today released a year-end Letter</a> from Chief Executive Officer Jody Aufrichtig, summarizing the Company’s 2025 achievements and outlining its strategic vision for 2026.In his year-end letter to shareholders, Aufrichtig described 2025 as a “turning point” in which Psyence BioMed delivered clinical execution, strengthened global manufacturing ties, and positioned itself at the forefront of the convergence between nature-derived psychedelic therapeutics and longevity science.“We recruited and dosed our first patients in a Phase IIb study. Through a further investment in <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://psylabs.life/">PsyLabs</a> we secured our psychedelic compound supply chain and became the only listed company with an investment in sustainable Ibogaine at source in Africa. We commenced studies in the exciting field of Longevity and ended the year debt free with over USD $9 million in cash reserves.”<h3>Clinical Progress and Phase IIb Trial Momentum</h3>Psyence BioMed advanced its Phase IIb clinical trial evaluating psilocybin-assisted psychotherapy for the treatment of Adjustment Disorder in palliative care. Multiple patients were dosed across several Australian clinical sites, supported by a partnership with Southern Star Research, one of Australia’s leading clinical research organisations.<h3>Advancing Nature-Derived Manufacturing and Supply Chain Leadership</h3>The Company strengthened its vertical integration through a multi-million-dollar follow-on investment in PsyLabs, securing GMP compliant nature-derived psilocybin and ibogaine supply for current and future programs. Psyence BioMed also announced a breakthrough in high purity ibogaine production, reinforcing its manufacturing advantage.<h3>Regulatory Tailwinds in Australia</h3>Aufrichtig noted the importance of the Australian Therapeutic Goods Administration’s (TGA) public consultation on psilocybin-assisted therapy for existential distress in patients with life-limiting illness – a development closely aligned with the Company’s clinical trial. If approved, the amendment would enable supervised access through the Authorised Prescriber framework and expand the eligible prescriber group to include palliative-care specialists.<img style="height:auto;" src="https://psyencebiomed.com/wp-content/uploads/2024/02/2.jpg" alt="" srcset="https://psyencebiomed.com/wp-content/uploads/2024/02/2-200x70.jpg 200w, https://psyencebiomed.com/wp-content/uploads/2024/02/2-400x140.jpg 400w, https://psyencebiomed.com/wp-content/uploads/2024/02/2-600x210.jpg 600w, https://psyencebiomed.com/wp-content/uploads/2024/02/2-800x280.jpg 800w, https://psyencebiomed.com/wp-content/uploads/2024/02/2-1200x420.jpg 1200w, https://psyencebiomed.com/wp-content/uploads/2024/02/2.jpg 2000w" sizes="100vw" width="2000" height="700"><h3>A Unique Position in Longevity Science</h3>“Psyence BioMed is currently the only publicly listed psychedelics company investing meaningfully in longevity science,” said Aufrichtig. “Our focus is on the emotional, neurobiological, and existential dimensions of aging, and we believe psychedelic-assisted therapy will play a central role in improving healthspan – not just lifespan.”<h3>2026 Outlook</h3>The Company plans to accelerate enrollment in its Phase IIb clinical trial, expand its manufacturing footprint, pursue additional longevity-focused indications, and evaluate strategic partnership opportunities throughout 2026.The full CEO Letter is available <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://psyencebiomed.com/ceo-year-end-letter-to-shareholders/">here</a>.<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://psyencebiomed.com/ceo-year-end-letter-to-shareholders/">CEO Letter 2025</a><h3>Forward Looking Statements</h3>This communication contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements include, but are not limited to, statements about future financial and operating results, our plans, objectives, expectations, and intentions with respect to future operations, products and services; and other statements identified by words such as “will likely result,” “are expected to,” “will continue,” “is anticipated,” “estimated,” “believe,” “intend,” “plan,” “projection,” “outlook” or words of similar meaning.Forward-looking statements in this communication include statements regarding the progress of the Phase IIb clinical trial, the expansion of the Company’s current and future programs, and the expansion of the Company’s manufacturing capabilities. These forward-looking statements are based on a number of assumptions, including the assumption that there will be no delays in the execution of the Phase IIb clinical trial implementation schedule, the Company will secure the necessary regulatory and other consents required to expand its current and future programs, and that the demand for psychedelic-assisted therapy will continue to increase. There can be no assurance that the Company will continue to maintain compliance with Nasdaq’s continued listing requirements. There are numerous risks and uncertainties that may cause actual results or performance to be materially different from those expressed or implied by these forward-looking statements.These risks and uncertainties include, among others: (i) delays in the execution of the Phase IIb trial; (ii) the ability of Psyence BioMed to maintain the listing of its common shares and warrants on Nasdaq; (iii) volatility in the price of the securities of Psyence BioMed due to a variety of factors, including the recent share consolidation, changes in the competitive and highly regulated industries in which Psyence BioMed operates, variations in performance across competitors, changes in laws and regulations affecting Psyence BioMed’s business and changes in Psyence BioMed’s capital structure. The foregoing list of factors is not exhaustive. You should carefully consider the foregoing factors and the other risks and uncertainties described in the “Risk Factors” section of the Company’s final prospectus (File No. 333-289285) filed with the Securities and Exchange Commission (the “SEC”) on November 3, 2025 and other documents filed by Psyence BioMed from time to time with the SEC.These filings identify and address other important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking statements. Actual results and future events could differ materially from those anticipated in such statements. Nothing in this communication should be regarded as a representation by any person that the forward-looking statements set forth herein will be achieved or that any of the contemplated results of such forward-looking statements will be achieved. You should not place undue reliance on forward-looking statements, which speak only as of the date they are made. Except as required by law, Psyence BioMed does not intend to update these forward-looking statements.The Company does not make any medical, treatment or health benefit claims about its proposed products. The U.S. Food and Drug Administration, Health Canada or other similar regulatory authorities have not evaluated claims regarding psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceutical products. The efficacy of such products has not been confirmed by authorized clinical research. There is no assurance that the use of psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceuticals can diagnose, treat, cure or prevent any disease or condition. Vigorous scientific research and clinical trials are needed. The Company has not conducted clinical trials for the use of the proposed products. Any references to quality, consistency, efficacy, and safety of potential products do not imply that the Company has verified such in clinical trials or that the Company will complete such trials. If the Company cannot obtain the approvals or research necessary to commercialize its business, it may have a material adverse effect on the Company’s performance and operations.Note: This article has been published automatically by sourcing from Access Newswire. The Stocktwits editorial team did not edit this article.

Psyence BioMed CEO Letter Highlights Clinical Progress, Ethical sourcing of Ibogaine, Strong Cash Position and Expanding Leadership in Longevity Science

Psyence BioMed summarized its successful 2025 clinical and supply-chain efforts, positioning for trial expansion and longevity research in 2026.

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NEW YORK, Nov. 25, 2025 (GLOBE NEWSWIRE) -- Psyence Biomedical Ltd. (Nasdaq: PBM) (“Psyence BioMed” or the “Company”), a biopharmaceutical company advancing nature-derived psilocybin and ibogaine therapies for unmet mental health needs, today announced the launch of a new psilocybin longevity research initiative in collaboration with leading researchers in South Africa. This program positions Psyence BioMed as the first – and currently the only – publicly listed company to investigate psilocybin’s potential impact on biological markers associated with aging and longevity. A successful trial could redefine human longevity and transform the future of aging.Longevity science is gaining unprecedented global attention, driven by rapidly aging populations, escalating healthcare costs, and the visibility of figures like Bryan Johnson, who has openly explored both psychedelic therapies and longevity optimization. Simultaneously, scientific literature continues to build support for the intersection of psychedelics and aging biology. Recent preclinical research has shown that psilocin, psilocybin’s active metabolite, extended survival in aged mouse models and increased the lifespan of human skin and lung cells by more than 50 per cent (<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=fYmoqTfCjBZWcGz8V1JskJhFG_uolRewQpV-bi1RaRsEryoNNMdonMrkWB3SqGWvWg0qhdj3GJWOxsqlXNgRrWQRcRs80DacDb0ArFTFfka8huTHNHeaTVQh9rj0eXMdFTqGcWkE8MdxnKz_E6UtlKazGIOIDwfqrsSKCx7HeD4=">Source</a>). Additional studies suggest psilocybin may modulate cellular aging by reducing oxidative stress, preserving telomere length, enhancing neuroplasticity, and activating key longevity-associated pathways (<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=fYmoqTfCjBZWcGz8V1JskCgz7HXxcl1tb1YSCpMByydkseHXd1kejdDKddRuuLPDK-IWX9sv3MK1GJmyxO84GKjb_CK-05Vpo8Y1eUrWdQHH34IQ1RIem6VnMUkvdHA7XWkMDIaiyS_6wlTKwqI0kviZ_gcQBhSFJPjwmxYN0p6OvPeP6VR4aydoQxv_-JFC">Source</a>).Working closely with an academic neuroscience faculty, Psyence BioMed is developing an accelerated preclinical protocol designed to evaluate whether psilocybin influences biological mechanisms tied to aging. The study will examine biomarkers related to cellular stress, inflammation, mitochondrial function, and behavioural indicators associated with healthspan and lifespan. The Company has commenced the project, with full acceleration anticipated early in the new year following ethics approval.The research will be conducted under the leadership of Dr. Tanya Calvey, PhD, an internationally recognized neuroscientist specializing in translational neuropsychopharmacology. Dr. Calvey’s work bridges human neuroimaging, molecular biology, and neurohistology to explore how psychoactive compounds influence long-term brain health and cellular resilience.“The scientific community is only beginning to uncover the potential links between psychedelics and longevity,” said Dr. Tanya Calvey. “Psilocybin modulates inflammation, neural connectivity, and cellular stress responses – all central to how we understand aging biology. The collaboration with Psyence BioMed enables us to rigorously investigate these mechanisms and generate evidence that could guide future human studies.”Psyence BioMed Chief Executive Officer, Jody Aufrichtig, reinforced the significance of this initiative, particularly within the broader longevity movement.“Longevity is quickly emerging as one of the most important global health frontiers,” said Aufrichtig. “With public influencers like Bryan Johnson elevating longevity science and exploring psychedelic-assisted interventions, there is tremendous interest in understanding how psilocybin may influence biological aging. As the first publicly listed company actively pursuing this research, Psyence BioMed is positioned at the forefront of an entirely new therapeutic arena.This longevity initiative complements Psyence BioMed’s ongoing clinical development programs, including its psilocybin-assisted therapy trial for existential distress in palliative care patients in Australia. Together, these programs advance the Company’s mission to explore the full therapeutic potential of psilocybin and ibogaine across multiple dimensions of human health – from mental wellness to long-term biological wellbeing.About Psyence BioMedPsyence Biomedical Ltd. (Nasdaq: PBM) is one of the few multi-asset, vertically integrated biopharmaceutical companies specializing in psychedelic-based therapeutics. It is the first life sciences biotechnology company focused on developing nature-derived (non-synthetic) psilocybin and ibogaine-based psychedelic medicine to be listed on Nasdaq. We are dedicated to addressing unmet mental health needs. We are committed to an evidence-based approach in developing safe, effective, and FDA-approved nature-derived psychedelic treatments for a broad range of mental health disorders.Contact Information for Psyence Biomedical Ltd. Email: <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=XQW2Y0Fa0-FxEjV63NYOwvGdk0cTKvWhozbeHJ0vxO29rFCcfLQstxrPLpBUpNfpzmrd4WxiYpyVt93o5_rum3uQX_s0CpKfLRE-YqYueIU=">ir@psyencebiomed.com</a>&nbsp;&nbsp;&nbsp; Media Inquiries: <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=IvKu5Pl-QkcNUcqTqZZulR2XWJNXenfNrThxr5pm_tykE-HvoIlt0QeDeOKiAW0TWyqdn-FnWuBNI9lobyAx6BJP3LgcG7giwPEsRKZ1LgNnPPOWbRVT7BEn6rOJZIaP">media@psyencebiomed.com</a> General Information: <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=q_k_pr10fWV3vFgPus8ajT5amCUP9DDYOL32eHu-y8PRIL8081Gb-xBMAOIFsRUJc6PMAK3guPgg2we_vz6cMQCMdbtGTyEVec13-UqEPkk=">info@psyencebiomed.com</a>Investor Contact: Michael Kydd Investor Relations Advisor <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=89WwssPQnVkGaFixvMLmnD8hcHVGC-sEEJew4-H1pRmWVfOMn6ryodmpOS-LnNNfMoRqMFxQPHQpQ4q8nrt0a2dVSxrDzeEA41eu0YkvFFAyJqomB54EkZkOOkFf0UIQ">michael@psyencebiomed.com</a>Forward Looking StatementsThis communication contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements include, but are not limited to, statements about future financial and operating results, our plans, objectives, expectations, and intentions with respect to future operations, products and services; and other statements identified by words such as “will likely result,” “are expected to,” “will continue,” “is anticipated,” “estimated,” “believe,” “intend,” “plan,” “projection,” “outlook” or words of similar meaning.Forward-looking statements in this communication include statements regarding the advancement of the Company's clinical development pipeline, the commencement of the anticipated study, and international interest in longevity science. These forward-looking statements are based on a number of assumptions, including the assumption that ongoing and future study results will be positive, definitive agreements governing the anticipated study will be successfully negotiated, finalized, and executed, the Company will obtain all such regulatory approvals as may be required to execute the anticipated study, that interest in longevity science will continue to grow and that the demand for psychedelic-containing products and related therapy will continue to increase. The Company cannot guarantee that the aforementioned agreements will be completed on the expected timeline or at all. Furthermore, there can be no assurance that the Company will continue to maintain compliance with Nasdaq’s continued listing requirements. There are numerous risks and uncertainties that may cause actual results or performance to be materially different from those expressed or implied by these forward-looking statements.These risks and uncertainties include, among others: (i) delays in the execution of the Company's drug development and clinical trial pipeline; (ii) the ability of Psyence BioMed to maintain the listing of its common shares and warrants on Nasdaq; (iii) volatility in the price of the securities of Psyence BioMed due to a variety of factors, including the recent share consolidation, changes in the competitive and highly regulated industries in which Psyence BioMed operates, variations in performance across competitors, changes in laws and regulations affecting Psyence BioMed’s business and changes in Psyence BioMed’s capital structure. The foregoing list of factors is not exhaustive. You should carefully consider the foregoing factors and the other risks and uncertainties described in the “Risk Factors” section of the Company’s final prospectus (File No. 333-298285) filed with the Securities and Exchange Commission (the “SEC”) on November 3, 2025&nbsp; and other documents filed by Psyence BioMed from time to time with the SEC.These filings identify and address other important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking statements. Actual results and future events could differ materially from those anticipated in such statements. Nothing in this communication should be regarded as a representation by any person that the forward-looking statements set forth herein will be achieved or that any of the contemplated results of such forward-looking statements will be achieved. You should not place undue reliance on forward-looking statements, which speak only as of the date they are made. Except as required by law, Psyence BioMed does not intend to update these forward-looking statements.The Company does not make any medical, treatment or health benefit claims about its proposed products. The U.S. Food and Drug Administration, Health Canada or other similar regulatory authorities have not evaluated claims regarding psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceutical products. The efficacy of such products has not been confirmed by authorized clinical research. There is no assurance that the use of psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceuticals can diagnose, treat, cure or prevent any disease or condition. Vigorous scientific research and clinical trials are needed. The Company has not conducted clinical trials for the use of the proposed products. Any references to quality, consistency, efficacy, and safety of potential products do not imply that the Company has verified such in clinical trials or that the Company will complete such trials. If the Company cannot obtain the approvals or research necessary to commercialize its business, it may have a material adverse effect on the Company’s performance and operations.Note: This article has been published automatically by sourcing from Access Newswire. The Stocktwits editorial team did not edit this article.

Psyence BioMed Announces Groundbreaking Psilocybin Longevity Research Program

First publicly listed company to actively investigate psilocybin’s potential impact on longevity

NEW YORK, November 20, 2025 – Psyence Biomedical Ltd. (Nasdaq: PBM) (“Psyence BioMed” or the “Company”), a biopharmaceutical company advancing nature-derived psilocybin and ibogaine therapies for unmet mental health needs, today announced &nbsp;it had established a sustainable supply of high-potency iboga bark from trusted sourcing channels with deep experience in the iboga trade and treatment field through its strategic partner, PsyLabs. This is a significant achievement for the Company as it prepares for the clinical development of ibogaine for substance use disorders and validates its investment in PsyLabs.This collaboration with PsyLabs is an important step in securing a long-term supply of high-quality active pharmaceutical ingredients. PsyLabs’ ibogaine is fully GMP-compliant, ensuring it meets the rigorous standards required for clinical development. The first 50 kg has already been received and is now being processed into ibogaine HCL – the purified, pharmaceutical-grade form of ibogaine designed for precise dosing in clinical research – and into Total Alkaloid Extracts, which preserve the broader spectrum of iboga alkaloids found in the natural plant. Together, these products will be supplied to the legal research and treatment industries, supporting both standardized clinical trials and research into full-spectrum therapeutic approaches.Investing in a sustainable approach ensures that ibogaine and related alkaloids derived from Tabernanthe iboga and Voacanga africana are ethically sourced and pharmaceutical grade. By prioritizing quality, sustainability, and respect for the cultural traditions connected to these plants – including fair benefit-sharing with source communities – the Company is building a vertically integrated supply chain that meets the highest standards while supporting the long-term viability of this essential resource.“A reliable, ethically sourced supply of ibogaine is critical to our development pipeline,” said Jody Aufrichtig, Chief Executive Officer of Psyence BioMed. “This achievement not only strengthens our ability to advance our ibogaine-based clinical programs but also positions Psyence BioMed as a global leader in the emerging ibogaine sector. As international interest in ibogaine continues to accelerate, securing a sustainable and culturally respectful supply chain gives us a meaningful competitive advantage and reinforces our commitment to scientific rigor, responsible innovation, and the preservation of traditional knowledge.”“From soil to science, we will continue to ensure our ibogaine is not only the purest on the market, but the most ethically sourced,” said Tony Budden, CEO of PsyLabs. “We’re building a new standard for what ethical psychedelic production can look like – where traditional knowledge holders are partners, not just suppliers.”Today’s announcement advances Psyence BioMed – together with PsyLabs – toward a leading role in shaping the future of ibogaine development for substance use disorders and other urgent mental health needs.Learn more at <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.psyencebiomed.com/">www.psyencebiomed.com</a> and on <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.linkedin.com/company/psyence-biomed-ltd/">LinkedIn.</a>About Psyence BioMedPsyence Biomedical Ltd. (Nasdaq: PBM) is one of the few multi-asset, vertically integrated biopharmaceutical companies specializing in psychedelic-based therapeutics. It is the first life sciences biotechnology company focused on developing nature-derived (non-synthetic) psilocybin and ibogaine-based psychedelic medicine to be listed on Nasdaq. We are dedicated to addressing unmet mental health needs, particularly in palliative care. The name ‘Psyence’ merges ‘psychedelics’ and ‘science,’ reflecting the company’s commitment to an evidence-based approach in developing safe, effective, and FDA-approved nature-derived psychedelic treatments for a broad range of mental health disorders.About PsyLabsPsyLabs is a psychedelic Active Pharmaceutical Ingredient (API) development company, federally licensed to cultivate, extract, and export psilocybin mushrooms and other psychedelic compounds including psilocin, mescaline, ibogaine, and dimethyltryptamine (DMT) to legal medical and research markets. The company has successfully exported psilocybin products to Canada, the UK, Portugal, and Slovenia, and supplies purified extracts to its UK-based CMO partner.PsyLabs operates from an ISO 22000-certified facility audited by the British Standards Institution, ensuring the highest standards of safety and traceability. With a focus on natural compound purification, regulatory support, and global distribution, PsyLabs is expanding its product pipeline to include ibogaine and other next-generation psychedelics.<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://psylabs.life/">www.psylabs.life</a>Contact Information for Psyence Biomedical Ltd.Email: <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="mailto:ir@psyencebiomed.com">ir@psyencebiomed.com</a>Media Inquiries: <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="mailto:media@psyencebiomed.com">media@psyencebiomed.com</a>General Information: <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="mailto:info@psyencebiomed.com">info@psyencebiomed.com</a>Phone: +1 416-477-1708Investor Contact:Michael KyddInvestor Relations Advisor<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="mailto:michael@psyencebiomed.com">michael@psyencebiomed.com</a>Forward Looking StatementsThis communication contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements include, but are not limited to, statements about future financial and operating results, our plans, objectives, expectations, and intentions with respect to future operations, products and services; and other statements identified by words such as “will likely result,” “are expected to,” “will continue,” “is anticipated,” “estimated,” “believe,” “intend,” “plan,” “projection,” “outlook” or words of similar meaning.Forward-looking statements in this communication include statements regarding the advancement of the clinical development pipeline of ibogaine and the quality of the ibogaine derived or containing products under development. These forward-looking statements are based on a number of assumptions, including the assumption that all parties involved in the ibogaine supply chain will retain such valid permits and licenses as may be required to carry out their activities and that the demand for psychedelic-containing products and related therapy will continue to increase. There can be no assurance that the Company will continue to maintain compliance with Nasdaq’s continued listing requirements. There are numerous risks and uncertainties that may cause actual results or performance to be materially different from those expressed or implied by these forward-looking statements.These risks and uncertainties include, among others: (i) delays in the execution of the Company’s drug development and clinical trial pipeline; (ii) the ability of Psyence BioMed to maintain the listing of its common shares and warrants on Nasdaq; (iii) volatility in the price of the securities of Psyence BioMed due to a variety of factors, including the recent share consolidation, changes in the competitive and highly regulated industries in which Psyence BioMed operates, variations in performance across competitors, changes in laws and regulations affecting Psyence BioMed’s business and changes in Psyence BioMed’s capital structure. The foregoing list of factors is not exhaustive. You should carefully consider the foregoing factors and the other risks and uncertainties described in the “Risk Factors” section of the Company’s final prospectus (File No. 333-298285) filed with the Securities and Exchange Commission (the “SEC”) on November 3, 2025&nbsp; and other documents filed by Psyence BioMed from time to time with the SEC.These filings identify and address other important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking statements. Actual results and future events could differ materially from those anticipated in such statements. Nothing in this communication should be regarded as a representation by any person that the forward-looking statements set forth herein will be achieved or that any of the contemplated results of such forward-looking statements will be achieved. You should not place undue reliance on forward-looking statements, which speak only as of the date they are made. Except as required by law, Psyence BioMed does not intend to update these forward-looking statements.The Company does not make any medical, treatment or health benefit claims about its proposed products. The U.S. Food and Drug Administration, Health Canada or other similar regulatory authorities have not evaluated claims regarding psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceutical products. The efficacy of such products has not been confirmed by authorized clinical research. There is no assurance that the use of psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceuticals can diagnose, treat, cure or prevent any disease or condition. Vigorous scientific research and clinical trials are needed. The Company has not conducted clinical trials for the use of the proposed products. Any references to quality, consistency, efficacy, and safety of potential products do not imply that the Company has verified such in clinical trials or that the Company will complete such trials. If the Company cannot obtain the approvals or research necessary to commercialize its business, it may have a material adverse effect on the Company’s performance and operations.Note: This article has been published automatically by sourcing from Access Newswire. The Stocktwits editorial team did not edit this article.

Psyence BioMed Reaches Major Breakthrough in Pharmaceutical-Grade Ibogaine Supply for Worldwide Clinical and Therapeutic Markets

Psyence BioMed (PBM) secured a sustainable, GMP-compliant supply of iboga bark via PsyLabs to advance its ibogaine clinical development for substance use disorders.

NEW YORK, Nov. 12, 2025 (GLOBE NEWSWIRE) -- Psyence BioMed (Nasdaq: PBM) (“Psyence BioMed” or the “Company”), a biopharmaceutical company advancing nature-derived psilocybin and ibogaine therapies for unmet mental health needs, today announced that, through its strategic investment in PsyLabs, it is now the only publicly listed psychedelics company with active operations and manufacturing capabilities based in Africa – the natural and original source of ibogaine.Derived from the Tabernanthe iboga shrub native to Central and West Africa, ibogaine has been used for generations in traditional healing and spiritual practices. Establishing a presence directly at the source strengthens traceable, sustainable, and responsible access to this rare compound. It also places Psyence BioMed in a uniquely advantageous position within the psychedelics sector, with direct access to ibogaine at its origin and the ability to control quality from source to finished product.PsyLabs operates from a GMP-compliant facility in Southern Africa, where it produces highly purified, EU GMP-grade psychedelic compounds from natural sources, including psilocybin and ibogaine. The Company’s vertical integration across cultivation, extraction, and purification strengthens security of supply and rapid scalability.Jody Aufrichtig, Chief Executive Officer of Psyence BioMed, stated:“Our investment in PsyLabs strengthens a world-class supply chain and positions us at the forefront of nature-derived psychedelic drug development. This is not just about sourcing compounds – it’s about building a sustainable, ethical, and science-driven platform that can deliver breakthrough therapies to patients globally.”Tony Budden, CEO of PsyLabs, added:“This unique footprint in Africa offers more than operational efficiency – it’s a strategic differentiator. Africa holds deep traditional knowledge and access to rare, valuable plant medicines. We’ve built our model around ethical sourcing and honoring this wisdom through science.”Psyence BioMed shareholders benefit from this presence, gaining early access to pipeline products, IP development, and supply channels as the global demand for psychedelic APIs accelerates.A Global Surge in Ibogaine InnovationMomentum surrounding ibogaine as a potential treatment for addiction and mental health disorders continues to accelerate worldwide. Recent observational research (<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=parpNCK3aMgMPAUyivXIbFPto0YeXtRl_53eIR-W6v2ToQtPvg5FNZpmJw64ZK3d9T8uphjwOKhodzMqBOGPwlBBV7FeONT0-wAgyqaqJCEwzu9TI7cIJNqKmskNyA3c">source</a>) has shown promising results for ibogaine in treating substance use and mood disorders, sparking growing interest in its potential for PTSD in veterans. In one 2024 study of 30 Special Operations Forces veterans with traumatic brain injuries – 77% of whom met PTSD criteria – participants who underwent ibogaine-assisted therapy in Mexico experienced immediate and significant reductions in PTSD symptoms, functional impairment, and suicidal ideation.Building on this growing body of evidence, in 2025, the State of Texas allocated $50 million to fund clinical research on ibogaine, establishing a consortium of universities, hospitals, and drug developers with the goal of developing a U.S. FDA-approved treatment for opioid use disorder and related conditions. The initiative, championed by former Governor Rick Perry, aims to position Texas as a leading center for psychedelic medicine research.At the same time, global pharmaceutical interest in ibogaine and its analogs is intensifying. In August 2025, AbbVie acquired Gilgamesh Pharmaceuticals’ investigational compound Bretisilocin, a novel therapy for major depressive disorder, and established Gilgamesh Pharma Inc. to continue developing its pipeline, including a cardio-safe ibogaine analog designed to retain ibogaine’s therapeutic benefits while reducing cardiac risk (<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=parpNCK3aMgMPAUyivXIbF7YyteJrT7CV2EXVGdVKZEzMaaN_gutwyCcbZX3tpFH1Qijq1dX8nHmlTjTJfWyWGW3YHEb-rkJ-ytbNLAp_l8gF0O0a5cGtRKNwBVQThp0WMgkW4oOZWwKh26BbTvIHHcc_um7j4wauOn5FAdo7QXzxWETdn4n-7fH8b1DF3GtAurpYrs6AEFfAgkgAHJlItZf-XKkNA-L3Qy4Okuq3962fzqmUnX7HJdkMR7rqimiasb_22XUj6T8lf9FcUWa0dVC4-PTwOVH5n-tBJ-noRs=">source</a>). The acquisition highlights the growing recognition of ibogaine’s clinical potential and advances the development of next-generation analogs – an area in which Psyence BioMed is already actively engaged through its operations, partnerships, and ongoing research.“When state governments like Texas are investing $50 million in ibogaine research and leading pharmaceutical companies like AbbVie are acquiring psychedelic-inspired assets, it validates what Psyence BioMed is building. By operating at the natural source in Africa, we are uniquely positioned to supply, study, and advance ibogaine as it transitions from traditional use to mainstream medicine,” added Aufrichtig.Psyence BioMed’s vertically integrated model offers secure, compliant, and ethical access to naturally derived ibogaine for research and development. As ibogaine moves into clinical and commercial phases, Psyence BioMed’s position at the intersection of science, sustainability, and supply chain control provides a critical foundation for the next generation of psychedelic medicine.About PsyLabsPsyLabs is a psychedelic Active Pharmaceutical Ingredient (API) development company, federally licensed to cultivate, extract, and export psilocybin mushrooms and other psychedelic compounds including psilocin, mescaline, ibogaine, and dimethyltryptamine (DMT) to legal medical and research markets. The company has successfully exported psilocybin products to Canada, the UK, Portugal, and Slovenia, and supplies purified extracts to its UK-based CMO partner.PsyLabs operates from an ISO 22000-certified facility audited by the British Standards Institution, ensuring the highest standards of safety and traceability. With a focus on natural compound purification, regulatory support, and global distribution, PsyLabs is expanding its product pipeline to include ibogaine and other next-generation psychedelics.www.psylabs.lifeAbout Psyence BioMedPsyence Biomedical Ltd. (Nasdaq: PBM) is one of the few multi-asset, vertically integrated biopharmaceutical companies specializing in psychedelic-based therapeutics. It is the first life sciences biotechnology company focused on developing nature-derived (non-synthetic) psilocybin and ibogaine-based psychedelic medicine to be listed on Nasdaq. We are dedicated to addressing unmet mental health needs, particularly in palliative care. The name ‘Psyence’ merges ‘psychedelics’ and ‘science,’ reflecting the company’s commitment to an evidence-based approach in developing safe, effective, and FDA-approved nature-derived psychedelic treatments for a broad range of mental health disorders.Learn more at www.psyencebiomed.com and on LinkedIn.Contact Information for Psyence Biomedical Ltd. Email: ir@psyencebiomed.com&nbsp; Media Inquiries: media@psyencebiomed.com General Information: info@psyencebiomed.com Phone: +1 416-477-1708Investor Contact: Michael Kydd Investor Relations Advisor michael@psyencebiomed.comForward Looking StatementsThis communication contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements include, but are not limited to, statements about future financial and operating results, our plans, objectives, expectations, and intentions with respect to future operations, products and services; and other statements identified by words such as “will likely result,” “are expected to,” “will continue,” “is anticipated,” “estimated,” “believe,” “intend,” “plan,” “projection,” “outlook” or words of similar meaning.Forward-looking statements in this communication include statements regarding the anticipated benefits to be derived by shareholders from a presence in Africa and the speed of the anticipated increase in demand for psychedelic APIs. These forward-looking statements are based on a number of assumptions, including the assumption that all parties involved in the ibogaine supply chain will retain such valid permits and licenses as may be required to carry out their activities and that the demand for psychedelic-containing products and related therapy will continue to increase. There can be no assurance that the Company will continue to maintain compliance with Nasdaq’s continued listing requirements. There are numerous risks and uncertainties that may cause actual results or performance to be materially different from those expressed or implied by these forward-looking statements.These risks and uncertainties include, among others: (i) delays in the execution of the Company's drug development and clinical trial pipeline; (ii) the ability of Psyence BioMed to maintain the listing of its common shares and warrants on Nasdaq; (iii) volatility in the price of the securities of Psyence BioMed due to a variety of factors, including the recent share consolidation, changes in the competitive and highly regulated industries in which Psyence BioMed operates, variations in performance across competitors, changes in laws and regulations affecting Psyence BioMed’s business and changes in Psyence BioMed’s capital structure. The foregoing list of factors is not exhaustive. You should carefully consider the foregoing factors and the other risks and uncertainties described in the “Risk Factors” section of the Company’s final prospectus (File No. 333-289285) filed with the Securities and Exchange Commission (the “SEC”) on November 3, 2025 and other documents filed by Psyence BioMed from time to time with the SEC.These filings identify and address other important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking statements. Actual results and future events could differ materially from those anticipated in such statements. Nothing in this communication should be regarded as a representation by any person that the forward-looking statements set forth herein will be achieved or that any of the contemplated results of such forward-looking statements will be achieved. You should not place undue reliance on forward-looking statements, which speak only as of the date they are made. Except as required by law, Psyence BioMed does not intend to update these forward-looking statements.The Company does not make any medical, treatment or health benefit claims about its proposed products. The U.S. Food and Drug Administration, Health Canada or other similar regulatory authorities have not evaluated claims regarding psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceutical products. The efficacy of such products has not been confirmed by authorized clinical research. There is no assurance that the use of psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceuticals can diagnose, treat, cure or prevent any disease or condition. Vigorous scientific research and clinical trials are needed. The Company has not conducted clinical trials for the use of the proposed products. Any references to quality, consistency, efficacy, and safety of potential products do not imply that the Company has verified such in clinical trials or that the Company will complete such trials. If the Company cannot obtain the approvals or research necessary to commercialize its business, it may have a material adverse effect on the Company’s performance and operations.Note: This article has been published automatically by sourcing from Access Newswire. The Stocktwits editorial team did not edit this article.

Psyence BioMed Establishes Ibogaine Operations in Africa Through Strategic Investment in PsyLabs

Psyence BioMed is now the only publicly listed psychedelics company with African operations and manufacturing for nature-derived psilocybin and ibogaine.

NEW YORK, Nov. 06, 2025 (GLOBE NEWSWIRE) -- Psyence Biomedical Ltd. (Nasdaq: PBM) (“Psyence BioMed” or the “Company”), a biopharmaceutical company advancing nature-derived psilocybin and ibogaine therapies for unmet mental health needs, today announced a major clinical milestone with multiple patients successfully dosed in its ongoing Phase IIb clinical trial evaluating nature-derived psilocybin, in combination with psychotherapy, as a potential treatment for Adjustment Disorder in palliative care.This achievement demonstrates significant clinical advancement and reinforces Psyence BioMed’s position as a global leader in late-stage psychedelic drug development. Following successful patient dosing across multiple trial sites, the Company is advancing the only active Australian clinical program using a natural psilocybin formulation to treat Adjustment Disorder in palliative care – one of the most rigorous studies of its kind globally.The Phase IIb study has been strategically designed to meet regulatory expectations for pivotal clinical evidence. Its larger sample size, rigorous randomization, and multi-site structure enhance statistical power, data reliability, and the generalizability of findings.Patients have now been dosed across two active clinical sites – the Empax Center in Perth and the Mind Medicine Australia Clinic in Melbourne – reflecting strong operational readiness, recruitment efficiency, and protocol execution. The Company has also activated Paratus Clinical Research in Melbourne to expand the study to three actively enrolling sites and accelerate data collection toward topline results anticipated by year-end 2026.“The randomization and dosing of these patients across multiple independent trial sites marks an exciting and validating milestone for Psyence BioMed,” said Dr. Clive Ward-Able, Medical Director of Psyence BioMed. “With multiple sites now operational and patients progressing through screening, we are seeing strong interest and momentum. This level of engagement reinforces the importance of our work in developing psilocybin-based therapies for palliative care.”The multi-site, double-blind, placebo-controlled study is designed to enroll 87 patients across Australia. Participants receive one of two therapeutic doses of psilocybin (10 mg or 25 mg) or a low-dose comparator (1 mg), each administered alongside structured psychotherapy. The study will assess efficacy, safety, and durability of response, with the goal of advancing psilocybin as a potential first-in-class treatment for Adjustment Disorder in palliative care settings.“This pivotal moment reflects the extraordinary effort and precision required to achieve multiple patient dosing across independent clinical sites,” said Jody Aufrichtig, Chief Executive Officer of Psyence BioMed. “It demonstrates not only our team’s operational excellence but also the maturity of our clinical infrastructure. With a trial design that meets rigorous regulatory standards, Psyence BioMed is generating high-quality data to support future approvals, commercial readiness, and the advancement of a nature-derived psilocybin therapy for patients facing adjustment disorder in palliative care.”About Psyence BioMedPsyence Biomedical Ltd. (Nasdaq: PBM) is one of the few multi-asset, vertically integrated biopharmaceutical companies specializing in psychedelic-based therapeutics. It is the first life sciences biotechnology company focused on developing nature-derived (non-synthetic) psilocybin and ibogaine-based psychedelic medicine to be listed on Nasdaq. We are dedicated to addressing unmet mental health needs, particularly in palliative care. The company is committed to an evidence-based approach in developing safe, effective, and FDA-approved nature-derived psychedelic treatments for a broad range of mental health disorders.Learn more at <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=GJ8pzeEUaInOE8JXAQHTJ0Smwm5ro2Ut1o2fllUBGUNF55WLsZiVtdIpwERbrzgRnkMRK05dIHpr7nMtBhJDg2ilJ3qXZK0vfJ7BKZkVfk4=">www.psyencebiomed.com</a> and on <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=W_QiWAp7vAMOlXdap48QHBxEV9z0DUOLHG-zG3oW00YH4DRBjx_bNEbxf7YUKkVWLxvYfwTLyHE4M4qe55f46u3zPo3Ko-UJaHWjOldJWVYAlco3lgmGwikYdDIRmmgW">LinkedIn.</a>Contact Information for Psyence Biomedical Ltd. Email: <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=i5YA-7fmi3ch7qqY9038SXOdjbrzPDbxbwyH4MqwyL3bvHyGkvLW1pfojT9ufClU6Pec-mBU4TNsF2rPeoa6PisGI186cNfARecoJSh_vMQ=">ir@psyencebiomed.com</a>&nbsp;&nbsp;&nbsp; Media Inquiries: <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=vSH0_WHIv4yJ-bTOinwBqnZwXG1m8dev27RLQ6MeKJwrcu0TxnNpFSAGeL9xrjE5yOcZ4T7cZm9_oKp5r-i6ghWG1KcXYwxBQ24gBKrWkxHxMiv_59_Vt3UISyA9ouPd">media@psyencebiomed.com</a> General Information: <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=G6uCHKkkDUkeH5h72b3NZjP8vnBh6gkgI9lfyiIGWV8fAKwfSpVQZbaIf4sxvGOmh61L8Owu94TV9nELX57JcVgBjIQ26Spr6UdrYd7OkRU=">info@psyencebiomed.com</a> Phone: +1 416-477-1708Investor Contact: Michael Kydd Investor Relations Advisor <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/Tracker?data=xmufE7WibFL8VdTA0EL0wzMXr8Rr7nVaIdcq8samjEWn5xAp4holcrpQ8WTrlvBy3QUK3d4oOHQc4HLgRj2kNxeG8NKfMzDnBC8AVCoow2TAlADxkR_zPR1_Y78HhRgX">michael@psyencebiomed.com</a>Forward Looking StatementsThis communication contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements include, but are not limited to, statements about future financial and operating results, our plans, objectives, expectations, and intentions with respect to future operations, products and services; and other statements identified by words such as “will likely result,” “are expected to,” “will continue,” “is anticipated,” “estimated,” “believe,” “intend,” “plan,” “projection,” “outlook” or words of similar meaning.Forward-looking statements in this communication include statements regarding the progress of the Phase IIb clinical trial, trial execution and patient enrollment and generation of trial results. These forward-looking statements are based on a number of assumptions, including the assumption that there will be no delays in the execution of the Phase IIb clinical trial implementation schedule, topline data from this trial will be positive, and that the demand for psychedelic-assisted therapy will continue to increase. There can be no assurance that the Company will continue to maintain compliance with Nasdaq’s continued listing requirements. There are numerous risks and uncertainties that may cause actual results or performance to be materially different from those expressed or implied by these forward-looking statements.These risks and uncertainties include, among others: (i) delays in the execution of the Phase IIb trial; (ii) the ability of Psyence BioMed to maintain the listing of its common shares and warrants on Nasdaq; (iii) volatility in the price of the securities of Psyence BioMed due to a variety of factors, including the recent share consolidation, changes in the competitive and highly regulated industries in which Psyence BioMed operates, variations in performance across competitors, changes in laws and regulations affecting Psyence BioMed’s business and changes in Psyence BioMed’s capital structure. The foregoing list of factors is not exhaustive. You should carefully consider the foregoing factors and the other risks and uncertainties described in the “Risk Factors” section of the Company’s final prospectus (File No. 333-289285) filed with the Securities and Exchange Commission (the “SEC”) on November 3, 2025 and other documents filed by Psyence BioMed from time to time with the SEC.These filings identify and address other important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking statements. Actual results and future events could differ materially from those anticipated in such statements. Nothing in this communication should be regarded as a representation by any person that the forward-looking statements set forth herein will be achieved or that any of the contemplated results of such forward-looking statements will be achieved. You should not place undue reliance on forward-looking statements, which speak only as of the date they are made. Except as required by law, Psyence BioMed does not intend to update these forward-looking statements.The Company does not make any medical, treatment or health benefit claims about its proposed products. The U.S. Food and Drug Administration, Health Canada or other similar regulatory authorities have not evaluated claims regarding psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceutical products. The efficacy of such products has not been confirmed by authorized clinical research. There is no assurance that the use of psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceuticals can diagnose, treat, cure or prevent any disease or condition. Vigorous scientific research and clinical trials are needed. The Company has not conducted clinical trials for the use of the proposed products. Any references to quality, consistency, efficacy, and safety of potential products do not imply that the Company has verified such in clinical trials or that the Company will complete such trials. If the Company cannot obtain the approvals or research necessary to commercialize its business, it may have a material adverse effect on the Company’s performance and operations.Note: This article has been published automatically by sourcing from Access Newswire. The Stocktwits editorial team did not edit this article.

Psyence BioMed Doses Multiple Patients and Expands Clinical Sites in Phase IIb Study for Adjustment Disorder in Palliative Care

Mind Medicine Australia clinic joins Psyence BioMed’s expanding network of clinical sites as enrollment accelerates in the landmark Phase IIb study for Adjustment Disorder in palliative care

NEW YORK, November 3, 2025 – Psyence Biomedical Ltd. (Nasdaq: PBM) (“Psyence BioMed” or the “Company”), a biopharmaceutical company advancing nature-derived psilocybin and Ibogaine therapies for unmet mental health needs, today announced it has made a USD$3,500,000 follow-on investment in PsyLabs, a leading producer of purified psychedelic active pharmaceutical ingredients (APIs).This investment solidifies PsyLabs’ position as a primary supplier of high-quality, GMP-grade psychedelic compounds, including psilocybin and ibogaine, for Psyence BioMed’s clinical research programs. The enhanced collaboration ensures Psyence BioMed continues to have access to an ethical, sustainable, and reliable supply of premium psychedelic compounds to advance its clinical pipeline. This investment made on August 15th, 2025, follows-on from the previously made USD$500,000 investment in PsyLabs in April 2025.“We are committed to advancing nature-derived psychedelics and building a responsible, global supply chain,” said Psyence BioMed Chief Executive Officer, Jody Aufrichtig. “This new investment is a deliberate step toward building a fully integrated company – from cultivation to clinical development. This strategic approach not only secures access to the highest quality compounds for our trials but also creates long-term value for our investors by ensuring sustainability, scalability, and competitive differentiation in a rapidly evolving market,” added Aufrichtig.PsyLabs’ state-of-the-art facility in Southern Africa utilizes the region’s rich botanical heritage to produce psychedelic compounds under strict ethical and sustainable practices. Psyence BioMed is the first publicly listed company with a dedicated investment in Southern African psychedelic production, underscoring the Company’s commitment to accessing regional expertise while advancing global psychedelic research.“This continued investment from Psyence BioMed is a testament to the strength of our partnership and the quality of our products,” said Tony Budden, CEO of PsyLabs. “We are proud to support Psyence BioMed’s pioneering clinical work with our premium, sustainably produced compounds.”With this expanded partnership, Psyence BioMed strengthens its leadership position in the emerging psychedelic therapeutics sector, advancing both near-term clinical development and long-term commercial opportunities.Certain executives, including the Chief Executive Officer, the Chief Financial Officer and the General Counsel, and an independent director, of Psyence BioMed, provide consulting services to PsyLabs in exchange for consulting fees. Such individuals own less than 5% of the outstanding shares of PsyLabs in the aggregate. Certain of these individuals are also members of the board of directors of a wholly owned subsidiary of PsyLabs.About Psyence BioMedPsyence Biomedical Ltd. (Nasdaq: PBM) is one of the few multi-asset, vertically integrated biopharmaceutical companies specializing in psychedelic-based therapeutics. It is the first life sciences biotechnology company focused on developing nature-derived (non-synthetic) psilocybin and ibogaine-based psychedelic medicine to be listed on Nasdaq. We are dedicated to addressing unmet mental health needs, particularly in palliative care. The name ‘Psyence’ merges ‘psychedelics’ and ‘science,’ reflecting the company’s commitment to an evidence-based approach in developing safe, effective, and FDA-approved nature-derived psychedelic treatments for a broad range of mental health disorders.Learn more at <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.psyencebiomed.com/">www.psyencebiomed.com</a> and on <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.linkedin.com/company/psyence-biomed-ltd/">LinkedIn.</a>About PsyLabsPsyLabs is a psychedelic Active Pharmaceutical Ingredient (API) development company, federally licensed to cultivate, extract, and export psilocybin mushrooms and other psychedelic compounds including psilocin, mescaline, ibogaine, and dimethyltryptamine (DMT) to legal medical and research markets. The company has successfully exported psilocybin products to Canada, the UK, Portugal, and Slovenia, and supplies purified extracts to its UK-based CMO partner.PsyLabs operates from an ISO 22000-certified facility audited by the British Standards Institution, ensuring the highest standards of safety and traceability. With a focus on natural compound purification, regulatory support, and global distribution, PsyLabs is expanding its product pipeline to include ibogaine and other next-generation psychedelics.<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.psylabs.life/">www.psylabs.life</a>Contact Information for Psyence Biomedical Ltd.Email: <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="mailto:ir@psyencebiomed.com">ir@psyencebiomed.com</a>Media Inquiries: <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="mailto:media@psyencebiomed.com">media@psyencebiomed.com</a>General Information: <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="mailto:info@psyencebiomed.com">info@psyencebiomed.com</a>Phone: +1 416-477-1708Investor Contact:Michael KyddInvestor Relations Advisor<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="mailto:michael@psyencebiomed.com">michael@psyencebiomed.com</a>Forward Looking StatementsThis communication contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements include, but are not limited to, statements about future financial and operating results, our plans, objectives, expectations, and intentions with respect to future operations, products and services; and other statements identified by words such as “will likely result,” “are expected to,” “will continue,” “is anticipated,” “estimated,” “believe,” “intend,” “plan,” “projection,” “outlook” or words of similar meaning.Forward-looking statements in this communication include statements regarding the advancement of the Company’s clinical pipeline and the creation of long-term shareholder value. These forward-looking statements are based on a number of assumptions, including the assumption that all parties involved in the ibogaine supply chain will retain such valid permits and licenses as may be required to carry out their activities and that the demand for psychedelic-containing products and related therapy will continue to increase. There can be no assurance that the Company will continue to maintain compliance with Nasdaq’s continued listing requirements. There are numerous risks and uncertainties that may cause actual results or performance to be materially different from those expressed or implied by these forward-looking statements.These risks and uncertainties include, among others: (i) delays in the execution of the Company’s drug development and clinical trial pipeline; (ii) the ability of Psyence BioMed to maintain the listing of its common shares and warrants on Nasdaq; (iii) volatility in the price of the securities of Psyence BioMed due to a variety of factors, including the recent share consolidation, changes in the competitive and highly regulated industries in which Psyence BioMed operates, variations in performance across competitors, changes in laws and regulations affecting Psyence BioMed’s business and changes in Psyence BioMed’s capital structure. The foregoing list of factors is not exhaustive. You should carefully consider the foregoing factors and the other risks and uncertainties described in the “Risk Factors” section of the Company’s final prospectus (File No. 333-298285) filed with the Securities and Exchange Commission (the “SEC”) on November 3, 2025 and other documents filed by Psyence BioMed from time to time with the SEC.These filings identify and address other important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking statements. Actual results and future events could differ materially from those anticipated in such statements. Nothing in this communication should be regarded as a representation by any person that the forward-looking statements set forth herein will be achieved or that any of the contemplated results of such forward-looking statements will be achieved. You should not place undue reliance on forward-looking statements, which speak only as of the date they are made. Except as required by law, Psyence BioMed does not intend to update these forward-looking statements.The Company does not make any medical, treatment or health benefit claims about its proposed products. The U.S. Food and Drug Administration, Health Canada or other similar regulatory authorities have not evaluated claims regarding psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceutical products. The efficacy of such products has not been confirmed by authorized clinical research. There is no assurance that the use of psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceuticals can diagnose, treat, cure or prevent any disease or condition. Vigorous scientific research and clinical trials are needed. The Company has not conducted clinical trials for the use of the proposed products. Any references to quality, consistency, efficacy, and safety of potential products do not imply that the Company has verified such in clinical trials or that the Company will complete such trials. If the Company cannot obtain the approvals or research necessary to commercialize its business, it may have a material adverse effect on the Company’s performance and operations.Note: This article has been published automatically by sourcing from Access Newswire. The Stocktwits editorial team did not edit this article.

Psyence BioMed Strengthens Strategic Partnership with PsyLabs Through USD $3,500,000 Follow-On Investment

Psyence BioMed made a $3.5 million follow-on investment in PsyLabs to secure a primary supply of high-quality psychedelic compounds for its clinical research programs.

U.S. biotech stocks, particularly small and mid-cap companies, remained a focal point for retail investors in 2024 despite significant volatility.&nbsp;Collectively, biotech stocks on U.S. bourses have garnered over 3.3 million watchers on Stocktwits.&nbsp;Here are the top five biotech stocks that saw the most significant surge in new followers this year:CERo Therapeutics Holdings Inc. (CERO): +44544% WatchersThis immunotherapy company develops engineered T-cell therapeutics for cancer. <a href="https://stocktwits.com/symbol/CERO">CERO</a> saw major retail interest following the FDA’s clearance of its lead compound, CER-1236, for Phase 1 clinical trials after an earlier clinical hold. The company went public via a SPAC merger in February and has lost 99% of its value this year.Psyence Biomedical Ltd. (PBM): +6741% WatchersKnown for developing natural psilocybin products for treating psychological trauma, PBM gained attention for positive results from its Phase IIb trial in adjustment disorder treatment for terminal cancer patients.&nbsp;Its&nbsp;shares have also dropped 99% this year since the company’s March SPAC debut.Azitra Inc. (AZTR): +2365% WatchersSpecializing in dermatological therapies using engineered proteins and live biotherapeutic products, AZTR drew attention for securing&nbsp;a fast track designation for ATR-04 and other multiple&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/why-are-azitra-shares-trending-on-wednesday/c7r4UW0RbE">patents</a>. Its stock value has plunged more than 99% since its debut in June last year.Immuneering Corporation (IMRX): +2248% WatchersFocused on oncology, IMRX’s lead program, IMM-1-104, received FDA orphan drug designation for pancreatic cancer and fast-track status to treat certain melanoma patients, and is currently in a Phase 2a trial. <a href="https://stocktwits.com/symbol/IMRX">IMRX shares</a> have declined over 70% year-to-date.NKGen Biotech Inc. (NKGN): +1260% WatchersNKGN develops autologous and CAR-NK cell therapies. Its SNK01 natural killer cell therapy for Alzheimer’s disease showed promising results, with 90% of patients maintaining or improving cognitive function. The candidate was cleared to progress into phase 2 clinical development, which will involve a larger group of 30 patients with moderate Alzheimer's disease. Shares, however, have fallen more than 66% this year.Despite their stock price struggles, these companies have captivated retail investors with groundbreaking therapies and promising clinical developments, positioning them as key biotech names to watch heading into 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

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Top 5 Biotech Stocks That Captured Retail Investor Interest The Most In 2024

Despite their stock price struggles, these companies have captivated retail investors with groundbreaking therapies and promising clinical developments.

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Newcourt Acquisition Corp. is a blank check company, which engages in the purpose of effecting a merger, share exchange, asset acquisition, share purchase, reorganization or similar business combination with one or more businesses. The company was founded on February 25, 2021 and is headquartered in Oakland, CA.

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