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ProShares Trust - ProShares Ultra Bloomberg Natural Gas 2x Shares

ProShares Ultra Bloomberg Natural Gas

ProShares Ultra Bloomberg Natural Gas ($BOIL) is experiencing a major surge as extreme cold weather forecasts, including polar vortex threats, fuel expectations for significantly increased natural gas demand across the US. The community is buzzing with predictions of a massive short squeeze, though some caution about the inherent volatility and historical patterns of natural gas's rapid movements.

Anteris Technologies Global Corp. is a structural heart company, which engages in the development and commercialization of medical devices for heart diseases. It operates through the following geographical segments: United States, Germany, Australia, Switzerland, and Sweden. The company was founded in 1999 and is headquartered in Eagan, MN.

Anteris Technologies Global Corp.

Anteris Technologies Global

Anteris Technologies Global (AVR) is trending following news of a strategic private placement with Medtronic and the enrollment of the first patients in its global pivotal PARADIGM trial for the DurAVR heart valve. The community is actively discussing the validation from Medtronic's investment and the significant milestone of advancing its core product, with many believing the stock remains undervalued despite recent share offerings.

Netflix, Inc. engages in providing entertainment services. It also offers activities for leisure time, entertainment video, video gaming, and other sources of entertainment. It operates through the United States and International geographic segments. The company was founded by Marc Randolph and Wilmot Reed Hastings on August 29, 1997 and is headquartered in Los Gatos, CA.

Netflix Inc.

Netflix Inc

Netflix is trending as its Q4 earnings beat was met with a cautious Q1 outlook and projections for increased content spending, creating a split in community sentiment. While many see the current dip as a significant buying opportunity, citing strong fundamentals and the potential content benefits from the pending Warner Bros. acquisition, others remain concerned about the associated debt, a pause in buybacks, and signs of maturing growth.

Galaxy Digital, Inc. engages in digital assets and data center infrastructure, delivering solutions that accelerate progress in finance and artificial intelligence. It operates through the following segments: Digital Assets and Data Centers. The digital assets segment offers institutional access to trading, advisory, asset management, staking, self-custody, and tokenization technology. The Data Centers segment competes with a range of infrastructure providers that are building or repurposing facilities to support the rapidly growing demand for AI and compute-intensive workloads. The company was founded by Michael Novogratz in 2018 and is headquartered in New York, NY.

Galaxy Digital Inc. - Ordinary Shares - Class A

Galaxy Digital is trending after securing significant ERCOT approval, doubling its Helios data center's total approved power capacity to over 1.6 gigawatts. This major development is leading community discussions to reposition GLXY as a key AI infrastructure player, moving beyond its traditional identity as solely a crypto proxy. Investors are anticipating new hyperscaler partnerships and a substantial re-evaluation of the company's market valuation, expecting higher price targets and significant long-term growth.

NVIDIA Corp. engages in the design and manufacture of computer graphics processors, chipsets, and related multimedia software. It operates through the following segments: Graphics Processing Unit (GPU) and Compute & Networking. The Graphics segment includes GeForce GPUs for gaming and PCs, the GeForce NOW game streaming service and related infrastructure, Quadro and NVIDIA RTX GPUs for enterprise workstation graphics, virtual GPU, or vGPU, software for cloud-based visual and virtual computing, automotive platforms for infotainment systems, and Omniverse Enterprise software for building and operating metaverse and 3D internet applications. The Compute & Networking segment consists of Data Center accelerated computing platforms and end-to-end networking platforms including Quantum for InfiniBand and Spectrum for Ethernet, NVIDIA DRIVE automated-driving platform and automotive development agreements, Jetson robotics and other embedded platforms, NVIDIA AI Enterprise and other software, and DGX Cloud software and services. The company was founded by Jen Hsun Huang, Chris A. Malachowsky, and Curtis R. Priem in April 1993 and is headquartered in Santa Clara, CA.

NVIDIA Corp

NVIDIA is actively discussed amidst significant market volatility, primarily influenced by evolving geopolitical trade concerns impacting the broader tech sector. Despite recent headlines, community discussion highlights immense demand for NVIDIA's AI chips, reportedly sold out through 2027, with many investors viewing current dips as a compelling buying opportunity. This showcases an ongoing tension between macro uncertainties and NVIDIA's foundational role in the rapidly expanding AI infrastructure.

Corvus Pharmaceuticals, Inc. engages in the development of immune modulator product candidates with the potential to treat solid cancers, T-cell lymphomas, autoimmune diseases, and infectious diseases. Its product pipeline includes B Cell Activator and Anti-CD73, Adenosine Production Inhibitor Anti-CD73, ITK Inhibitor, A2AR Inhibitor, Anti-CXCR2, and A2BR Inhibitor. The company was founded by Richard A. Miller, Peter A. Thompson, Joseph J. Buggy, and Erik Verner on January 27, 2014 and is headquartered in South San Francisco, CA.

Corvus Pharmaceuticals Inc

Corvus Pharmaceuticals is trending following robust Phase 1 clinical trial results for its eczema treatment, soquelitinib, which demonstrated significant efficacy and a favorable safety profile. This promising data initially drove a notable surge, but the company's subsequent announcement of a proposed public offering has ignited community debate over potential share dilution and its implications for future trials.

Teladoc Health, Inc. engages in the provision of telehealthcare services using a technology platform via mobile devices, the Internet, video and phone. It operates through the following segments: Teladoc Health Integrated Care, BetterHelp, and Others. The Teladoc Health Integrated Care segment offers virtual medical services. The BetterHelp segment includes virtual mental health and other wellness services. The company was founded in June 2002 by George Byron Brooks, Michael Gorton, and Gary Wald and is headquartered in New York, NY.

Teladoc Health Inc

Teladoc Health is a trending topic amidst a polarized community, grappling with concerns over its substantial convertible notes maturing in 2027 and persistent criticism of its leadership despite holding a significant market position. Many investors see deep value in its role within the rapidly expanding AI healthcare sector and potential gains from rural health initiatives, while others demand a management overhaul to realize this potential.

Definium Therapeutics, Inc. operates as clinical stage biopharmaceutical company, which engages in developing novel product candidates to treat brain health disorders. The company was founded by Stephen L. Hurst, Scott M. Freeman, Leonard Latchman and Jamon Alexander Rahn on July 26, 2010 and is headquartered in New York, NY.

Definium Therapeutics Inc.

Mind Medicine Inc - Ordinary Shares (Sub Voting)

Mind Medicine, now rebranded as Definium Therapeutics (DFTX), is a central topic of discussion following its ticker change and recent positive Phase 2b clinical trial data. The community is actively debating the rebrand while also highlighting the significant potential of MM120 (LSD) for Generalized Anxiety Disorder after its data was published in JAMA, generating widespread media attention and bullish analyst price targets. This development positions the company as a key player in the evolving psychedelic therapeutics sector.

Salesforce, Inc. engages in the design and development of cloud-based enterprise software for customer relationship management. Its solutions include sales force automation, customer service and support, marketing automation, digital commerce, community management, collaboration, industry-specific solutions, and salesforce platform. The firm also provides guidance, support, training, and advisory services. The company was founded by Marc Russell Benioff and Parker Harris in 1999 and is headquartered in San Francisco, CA.

Salesforce Inc

Salesforce is trending due to a significant sell-off in the broader software sector, driven by pervasive investor concerns about AI's disruptive impact on traditional SaaS models. Community sentiment is sharply divided, with some fearing AI will make CRM obsolete while others strongly believe its deep data moat and integrated AI solutions, like Agentforce, position it for long-term growth. This divergence has led many to view the current valuation as an irrational overreaction, presenting a compelling accumulation opportunity.

United States Commodity Funds LLC - United States Natural Gas Fund

United States Natural Gas Fund, LP

United States Natural Gas Fund (UNG) is experiencing significant market attention as natural gas futures surge, primarily fueled by widespread brutal cold weather forecasts and the threat of a polar vortex, which is driving up heating demand. Community chatter highlights both intense bullish sentiment anticipating a short squeeze and cautious notes regarding the commodity's historical volatility and supply dynamics. Amidst this weather-driven momentum, discussions also emphasize natural gas's long-term role in powering the rapidly expanding AI data center infrastructure.

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Wall Street analysts downgraded Regulus Therapeutics on Wednesday following its acquisition by Swiss drugmaker Novartis, citing limited room for upside after the deal valued Regulus at up to $1.7 billion.JonesResearch cut its rating to ‘Hold’ from ‘Buy’ and lowered its price target to $7 from $8, calling the offer “highly favorable” in light of Regulus’ upcoming Phase 3 trial financing needs, according to The Fly.Canaccord Genuity also&nbsp;reportedly downgraded the stock to ‘Hold,’ slashing its target to $11 from $28.&nbsp;Meanwhile,&nbsp;Wells Fargo reportedly cut its rating on Regulus to ‘Equal Weight’ from ‘Overweight,’ raising its target to $9 from $6 to reflect the contingent value right (CVR) component. Leerink Partners and Oppenheimer issued similar downgrades.Under the&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/regulus-therapeutics-stock-rockets-on-novartis-buy-offer/chXTfRKRbiP">agreement</a>, Regulus shareholders will receive $7 per share in cash and an additional $7 via a CVR, contingent on U.S. regulatory approval of its lead candidate, farabursen.&nbsp;The upfront payment represents a 108% premium to Regulus’ April 29 closing price and a 274% premium to its 60-day volume-weighted average.&nbsp;The transaction, unanimously approved by both companies’ boards, is expected to close in the second half of 2025, pending regulatory approvals and majority shareholder tender.Shares of Regulus surged to their highest levels since 2021 following the news and are up 6.4% year-to-date, while Novartis has gained 4.8%, both outperforming broader markets.The Dow is down 4.1%, the S&amp;P 500 has lost 5.1%, and the Nasdaq is off 1.6% over the same period.On Stocktwits, 24-hour message volume for Regulus jumped by 2,863% amid “extremely bullish” sentiment.One user congratulated Regulus shareholders, particularly recent buyers, and suggested that the growing interest in rare diseases could make companies like Protalix BioTherapeutics, Zevra Therapeutics, and Esperion Therapeutics potential targets going forward.<stembedurl>https://stocktwits.com/OldManLogan/message/613115970</stembedurl>Another Stocktwits user speculated that Regulus shares could double from current levels, fueled by FDA-related optimism and the potential for a competing bid to top Novartis' offer.<stembedurl>https://stocktwits.com/ST_Tropez_Trading/message/613203730</stembedurl>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, the Regulus Therapeutics logo is seen displayed on a smartphone screen. (Photo Illustration by Thomas Fuller/SOPA Images/LightRocket via Getty Images)

Regulus Downgraded By Analysts After $1.7B Novartis Buyout Offer — Street Sees Limited Upside Ahead

Regulus Therapeutics shares surged after Novartis announced a $1.7 billion acquisition, but analysts downgraded the stock citing limited upside. Retail sentiment remained bullish, with speculation of a higher bid or FDA-driven gains.

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Shares of biopharmaceutical company Regulus Therapeutics Inc. (RGLS) shot up 138% at the opening bell on Wednesday after Swiss drugmaker Novartis agreed to acquire the firm for up to $1.7 billion.As per the terms of the <a target="_blank" rel="noopener noreferrer nofollow" href="https://ir.regulusrx.com/2025-04-30-Regulus-Therapeutics-Enters-into-Agreement-to-be-Acquired-by-Novartis-AG">deal</a>, Novartis, through a subsidiary, will initiate a tender offer to acquire all of Regulus' outstanding shares for an initial price of $7.00 per share or $800 million. The initial per-share price represents a premium of 108% to Regulus' closing price on April 29.Regulus shareholders will also receive a contingent value right (CVR) of $7.00 per share if its lead product candidate, farabursen, receives regulatory approval.The total consideration, including the CVR, would be approximately $1.7 billion.Regulus’ farabursen is an investigational microRNA inhibitor designed to reduce the growth of cysts and kidney size, as well as delay progression of disease severity in a severe kidney disease called autosomal dominant polycystic kidney disease (ADPKD).Novartis President Shreeram Aradhye noted that there are limited treatment options currently available for ADPKD.“The team at Regulus has done meaningful foundational work with farabursen, and we look forward to investigating its potential further as we aim to bring a better treatment option to patients in need," he said.The transaction is expected to be completed in the second half of 2025. Until then, Regulus will continue to operate as a separate and independent company. Following the completion of the deal, Regulus will become an indirect wholly-owned subsidiary of Novartis.<a href="https://stocktwits.com/symbol/RGLS">RGLS stock</a> is up by 397% so far this year and by 237% over the past 12 months.Also See: <a href="https://stocktwits.com/news-articles/markets/equity/humana-reports-upbeat-q1-earnings/chXT9duRbiT">Humana Reports Upbeat Q1 Earnings, Reaffirms Full-Year Guidance</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

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Regulus Therapeutics Stock Skyrockets On $1.7B Acquisition Offer From Novartis

According to the terms of the deal, Novartis, through a subsidiary, will initiate a tender offer to acquire all of Regulus' outstanding shares for an initial price of $7.00 per share or $800 million.

Regulus Therapeutics, Inc. is a clinical-stage biopharmaceutical company, which engages in the discovery and development of drugs targeting microRNAs. Its two lead product candidates, RG-012 and RGLS4326, are in clinical development. RG-012 is an anti-miR targeting miR-21 in Phase II clinical trial for the treatment of Alport syndrome, a life-threatening kidney disease. RGLS4326 is an anti-miR targeting miR-17 in Phase I clinical trial for the treatment of autosomal dominant polycystic kidney disease. The firm is also developing a pipeline of preclinical drug product candidates in renal, hepatic, and central nervous systems diseases. The company was founded in 2007 and is headquartered in San Diego, CA.

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