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Pfizer Inc. is a research-based global biopharmaceutical company, which engages in the discovery, development, manufacture, marketing, sales and distribution of biopharmaceutical products worldwide. The firm works across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases. The company was founded by Charles Pfizer Sr. and Charles Erhart in 1849 and is headquartered in New York, NY.

Pfizer Inc.

Pfizer Inc

Pfizers sustained rally to a 52-week high and push through a long-watched round-number level are driving attention, with holders celebrating the recovery while skeptics question whether it can hold without a stronger company-specific catalyst. Traders are also watching the upcoming earnings report and pipeline developments for confirmation.

SPDR S&P 500 ETF TRUST - SPDR S&P 500 ETF Trust

Traders are focused on reports that Trump ruled out an immediate U.S. strike on Iran, with many interpreting the news as a possible relief-driven futures bounce while others argue conflict and oil-supply risks are merely delayed. The debate is amplifying an already cautious, volatile outlook ahead of the Fed decision, major tech earnings and inflation data.

Centrus Energy Corp. engages in the supply of nuclear fuel and services for the nuclear power industry. It operates through the Low-Enriched Uranium (LEU) and Technical Solutions segments. The LEU segment includes various components of nuclear fuel to utilities from its global network of suppliers. The Technical Solutions segment offers advanced engineering, design, and manufacturing services to government and private sector customers, and is deploying advanced nuclear fuel production capabilities to power existing, and next-generation reactors around the world. The company was founded in October 1992 and is headquartered in Bethesda, MD.

Centrus Energy Corp - Ordinary Shares - Class A

Centrus Energy Corp 

Centrus stock-and-warrant offering has intensified concern about shareholder dilution and contributed to a steep selloff, alongside broader weakness in nuclear stocks. Traders are divided between viewing the pullback as a buying opportunity tied to domestic uranium-enrichment demand and worrying that valuation, expansion costs, and execution risks outweigh the long-term HALEU and DOE-contract potential.

Alpha Tau Medical Ltd. is a clinical-stage oncology therapeutics company, which focuses on the research, development, and commercialization of diffusing alpha-emitters radiation therapy for the treatment of cancer. The firm is involved in the clinical trials at cancer centers with indications that include skin cancer, oral cavity cancer, breast cancer, and pancreatic cancer. The company was founded by Uzi Sofer, Yona Keisari, and Itzhak Kelson in November 2015 and is headquartered in Jerusalem, Israel.

Alpha Tau Medical Ltd

ALPHA TAU MEDICAL LTD

FDA clearance to expand Alpha Taus recurrent glioblastoma REGAIN trial and anticipated follow-up data are driving attention, alongside progress in its pancreatic cancer program. Traders are optimistic about the early GBM signal but acknowledge that it comes from a small cohort and await larger-data validation.

Twist Bioscience Corp. engages in the development of a proprietary semiconductor-based synthetic DNA manufacturing process. It operates through the following geographical segments: Americas, EMEA, and APAC. The Americas segment consists of the United States of America, Canada, Mexico, and South America. The EMEA segment includes Europe, Middle East, and Africa. The APAC segment focuses on Japan, China, South Korea, India, Singapore, Malaysia, and Australia. The company was founded by William Marine Banyai, Emily Marine Leproust, and Bill James Peck in 2013 and is headquartered in San Francisco, CA.

Twist Bioscience Corp

Discussion is focused on the $17.05 million investor settlement: eligible shareholders are being reminded to file claims before the deadline, with a final approval hearing scheduled immediately afterward. Some traders view clearing the legal overhang as a positive, while others emphasize the settlements limited per-share recovery and historical allegations about Twists production and financial disclosures.

VanEck ETF Trust - VanEck Gold Miners ETF

VanEck Gold Miners ETF

Golds pullback and concern that hotter inflation could keep interest rates higher are weighing on gold-miner shares, which can magnify moves in bullion. Traders are divided between buying the decline and expecting more downside, while watching for signs that gold and miners can stabilize.

ProShares Trust II - ProShares Ultra Bloomberg Natural Gas 2x Shares

ProShares Ultra Bloomberg Natural Gas

Volatile natural-gas futures are driving discussion, with traders weighing winter-weather demand and storage reports against mild-weather forecasts, strong production, and ample supply; pipeline and Freeport disruptions have also sparked sharp moves. Views are split on whether gas can sustain a rebound, while many warn that BOILs leveraged futures exposure and decay make it especially risky to hold.

United States Oil Fund LP - United States Oil Fund

United States Oil Fund

USO is drawing attention as crude rallies on fears that escalating Iran and broader Middle East tensions could disrupt oil supplies and shipping. Bulls see tight supply and continued geopolitical risk supporting the move, while bears argue the rally may be overextended and could reverse if tensions ease or a deal emerges.

ProShares Trust - ProShares UltraPro Short QQQ -3x Shares

ProShares UltraPro Short QQQ

Traders are focused on SQQQ as a leveraged hedge against the Nasdaq, citing tech weakness and concerns that heavy AI spending may not deliver adequate returns, alongside interest-rate and geopolitical risks. Some expect further downside in tech and favor SQQQ, while others caution that its daily leverage can erode value and that a Nasdaq rebound could reverse its gains.

Amgen, Inc. is a biotechnology company, which engages in the discovery, development, manufacture, and marketing of human therapeutics. The company was founded by William K. Bowes, Jr., Franklin Pitcher Johnson, Jr., George B. Rathmann, and Joseph Rubinfeld on April 8, 1980 and is headquartered in Thousand Oaks, CA.

AMGEN Inc.

Amgens Phase 3 lung-cancer results for IMDELLTRA plus Imfinzi are drawing attention, with traders focused on the reported survival benefit and potential to expand the drugs role in earlier treatment. The community views the data as a meaningful pipeline catalyst, though some question how much it will change Amgens broader growth outlook.

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Iran Opens Strait Of Hormuz To All But ‘Enemy’ Ships – While Crude Oil Rally Pushes Bets

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The Strait of Hormuz, a maritime chokepoint that transports 20% of the world's oil and liquefied natural gas, has become a significant point of contention in the current US-Iran crisis. 


USCF ETF Trust - USCF Oil Plus Bitcoin Strategy Fund

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<ul class="summary-bullets"><li>Iran said ships from all but “enemy” states may transit the Strait of Hormuz with security coordination, as President Donald Trump issued a 48-hour ultimatum threatening strikes if the waterway is not fully reopened.</li><li>Oil markets rallied amid fears of supply disruption at the chokepoint, pushing Brent crude above $112 per barrel and fueling renewed volatility in the energy market.</li><li>On-chain data shows a wallet linked to Sky co-founder Rune holds roughly $4.02 million in equity and about $5.5 million in unrealized gains.</li></ul>Iran announced a partial reopening of the Strait of Hormuz on Sunday, stating that ships from all but "enemy" states may pass through the vital waterway, provided they make security arrangements.&nbsp;The&nbsp;<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.mehrnews.com/news/6763848/%D8%B3%DB%8C%D8%A7%D8%B3%D8%AA-%D9%87%D9%88%D8%B4%D9%85%D9%86%D8%AF%D8%A7%D9%86%D9%87-%D8%A7%DB%8C%D8%B1%D8%A7%D9%86-%D8%AF%D8%B1-%D8%AA%D9%86%DA%AF%D9%87-%D9%87%D8%B1%D9%85%D8%B2-%D9%85%D8%B3%D8%AF%D9%88%D8%AF%D8%B3%D8%A7%D8%B2%DB%8C-%DA%AF%D8%B2%DB%8C%D9%86%D8%B4%DB%8C-%D8%A8%D9%87-%D8%AC%D8%A7%DB%8C-%D8%A7%D9%86%D8%B3%D8%AF%D8%A7%D8%AF">announcement</a> coincides with a 48-hour ultimatum from U.S. President Donald Trump and a spike in oil prices due to concerns about growing supply disruptions. "If Iran does not FULLY OPEN, WITHOUT THREAT, the Strait of Hormuz within 48 HOURS from this exact point in time, the United States of America will hit and obliterate their various POWER PLANTS, STARTING WITH THE BIGGEST ONE FIRST," stated U.S. President Donald Trump in a social media&nbsp;<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://truthsocial.com/@realDonaldTrump/posts/116269822349947644">post</a> on Saturday.<figure class="image"><img src="https://news.stocktwits-cdn.com/Screenshot_2026_03_22_at_5_22_11_AM_png_23c38aa297.webp" alt="Screenshot 2026-03-22 at 5.22.11 AM.png" width="490" height="250"><figcaption>Donald Trump's post on Truth Social.&nbsp;</figcaption></figure>The remarks come amid heightened geopolitical tensions and renewed energy market volatility, with crude prices rising amid concerns about supply disruptions at the strategic chokepoint that manages a sizable portion of global oil flows.<h2 class="st-heading-2">Why Is The Strait Of Hormuz Conflict Notable?</h2>About 20% of the world's oil and liquefied natural gas passes through the Strait of Hormuz, a narrow but crucial maritime chokepoint that has turned into a major flashpoint in the 2026 Middle East conflict.&nbsp;Iran launched retaliatory missile and drone attacks throughout the region in response to a series of coordinated U.S.-Israeli military strikes on Iran, including <a href="https://stocktwits.com/news-articles/markets/cryptocurrency/trump-us-strike-on-iran-khamenei-crypto-markets/cZdcYPvRIc3">the assassination of</a> Iran's supreme leader Ali Khamenei in late February. This led to an open conflict between Iran and the combined forces of Israel and the United States. Iran has responded by limiting and successfully disrupting commercial traffic through the strait, attacking merchant ships, planting mines, and now threatening to bar ships from "enemy" nations.<h2 class="st-heading-2">Global Oil Supply Shock</h2>The sharp increase in energy markets was highlighted by Brent crude futures, which recently traded above $112 per barrel, rising more than 3% on the day and extending gains to over 50% over the past month.&nbsp;<a href="https://stocktwits.com/symbol/USO">United States Oil Fund, LP (USO)</a> was down over 1% in after-hours trading. On Stocktwits, retail sentiment around USO remained in ‘bearish’ territory, with ‘high’ chatter levels over the past day.&nbsp;<figure class="image"><img src="https://news.stocktwits-cdn.com/Screenshot_2026_03_22_at_5_47_33_AM_png_5edbc721e0.webp" alt="Screenshot 2026-03-22 at 5.47.33 AM.png" width="1156" height="148"><figcaption>USO retail sentiment and message volume on March 22 as of 5:49 a.m. ET | Source: Stocktwits</figcaption></figure><a href="https://stocktwits.com/symbol/BNO">United States Brent Oil Fund, LP (BNO)</a> was down 0.4% in after-hours. On Stocktwits, retail sentiment around BNO remained in ‘neutral’ territory, with ‘high’ chatter levels over the past day.&nbsp;<figure class="image"><img src="https://news.stocktwits-cdn.com/Screenshot_2026_03_22_at_5_48_19_AM_png_ba61424a1d.webp" alt="Screenshot 2026-03-22 at 5.48.19 AM.png" width="1138" height="140"><figcaption>BNO retail sentiment and message volume on March 22 as of 5:49 a.m. ET | Source: Stocktwits</figcaption></figure><h2 class="st-heading-2">Oil Bets Lead To Major Profit</h2>Sky's co-founder, Rune, currently has a wallet address with about $4.02 million in total holdings, with about $3.29 million concentrated in leveraged perpetual futures positions and about $733,700 in spot assets, according to on-chain&nbsp;<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://hypurrscan.io/address/0x30d3ca3bed41c08e98fbdf671418421a76ee019a#txs">data</a> from Hyperscan.&nbsp;With an overall leverage of roughly 1.7 times and total unrealized gains of roughly $5.5 million across its open positions, the account has maintained long positions in Brent crude, WTI crude (CL), and the S&amp;P 500. A concentrated capital inflow of slightly more than $4 million in Circle’s (CRCL) stablecoin USDC from Arbitrum (ARB). This was followed by active rotation through sizable buy and sell orders, including a recent TWAP execution that raised exposure to WTI crude.The leveraged wallet seems to be benefiting from the current crude price rally, which has underpinned a marked turnaround in crude-linked perpetual positions on Hyperliquid (HYPE), shifting them from losses to significant floating profits.&nbsp;<a href="https://stocktwits.com/symbol/WTIB">The USCF Oil Plus Bitcoin Strategy Fund (WTIB)</a> which provides exposure to both crude oil and Bitcoin (BTC) was up 0.17% in after hours after closing over 3% on Friday. On Stocktwits retail sentiment around WTIB remained in ‘neutral’ territory, with ‘high’ chatter levels over the past day.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/glenmark-debuts-budget-semaglutide-in-india/cZ3i3maRIih">Glenmark Debuts Budget Semaglutide In India, Undercutting Ozempic By Over 80%</a> For updates and corrections, email newsroom[at]stocktwits[dot]com.

Fossil Fuel Prices Remain Volatile Due To War In The Middle East (Photo by Finnbarr Webster/Getty Images)

The Strait of Hormuz, a maritime chokepoint that transports 20% of the world's oil and liquefied natural gas, has become a significant point of contention in the current US-Iran crisis. 

Strait Of Hormuz Risks Rise As Iran Curbs Access For ‘Enemy’ States

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