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Siyata Mobile, Inc. engages in the provision of cellular communications systems for enterprise customers. It specializes in connected vehicle products for professional fleets, marketed under the Uniden Cellular and Siyata brands. The firm operates through the following geographical segments: Europe, the Middle East and Africa; Unites States; Canada; and Australia and New Zealand. The company was founded by Marc Seelenfreund on October 15, 1986 and is headquartered in Montreal, Canada.

Core AI Holdings Inc.

Core AI Holdings, Inc.

Core AI Holdings ($CHAI) is trending due to the finalization of its merger with Core Gaming, alongside a reverse stock split and ticker change, leading to confusion and volatility. The community is actively discussing the stock's halted trading, the impact of the merger and reverse split on share value, and platform display issues, while also speculating about potential short squeezes and long-term prospects in the AI gaming sector. With a relatively small float, many are closely watching for any news or PR from management to better understand the bull case.

Galecto, Inc. is a clinical-stage biotechnology company, which engages in developing novel small molecule therapeutics that are designed to target the biological processes that lie at the heart of cancer and fibrotic diseases. The firm is also involved in the development of small molecule inhibitors of galectin-3 and LOXL2. The company was founded by Ulf Jörgen Nilsson, Hakon Leffler, Tariq Sethi, and Hans Thalsgård Schambye in 2011 and is headquartered in Boston, MA.

Galecto Inc

GLTO is experiencing significant interest and volatility, with community members discussing potential halts and price targets, possibly fueled by momentum similar to other recent runners. The stock's low float and potential for a squeeze are key discussion points, with some comparing it to previous high-flying stocks. Chatter also mentions potential news or catalysts that could be driving the price action, though nothing is confirmed.

Spruce Biosciences, Inc. is a biopharmaceutical company, which engages in developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical need. The company was founded on November 13, 2014 and is headquartered in South San Francisco, CA.

Spruce Biosciences Inc

SPRB is trending due to a significant surge following positive news, potentially an FDA breakthrough designation; the community is comparing it to other high-flying stocks and discussing potential profit-taking strategies. Some traders are pointing to the low float as a key factor, while others suggest caution due to the rapid gains.

Trilogy Metals, Inc. engages in the development and exploration of mineral properties. The firm holds interests in the Upper Kobuk mineral projects that include the Arctic, a copper-zinc-lead-gold-silver and Bornite, a carbonate-hosted copper projects, which is located in the Ambler mining district in Northwest Alaska. The company was founded on April 27, 2011 and is headquartered in Vancouver, Canada.

Trilogy Metals Inc

TMQ is trending following news that the U.S. government will take a 10% stake in the company to support mining exploration in Alaska. The community is discussing the potential for a short squeeze and the stock's potential to reach double digits, while some express caution about a possible sell-off or secondary offering. The move aligns with broader efforts to secure domestic mineral resources.

Archer Aviation, Inc. engages in the development of electric vertical take-off and landing (eVTOL) aircraft. The company was founded by Brett Adcock and Adam Goldstein on October 16, 2018, and is headquartered in San Jose, CA.

Archer Aviation Inc - Ordinary Shares - Class A

Archer Aviation Inc

Archer Aviation ($ACHR) is trending amid speculation of a potential partnership with Tesla ($TSLA) following a teaser video, driving significant trading volume and a surge in call options. The community is actively discussing the possibility of a collaboration, while also weighing the company's fundamentals and upcoming milestones, regardless of any Tesla deal. Some traders are expressing caution, noting the risk of a pullback if the Tesla rumors prove false.

TMC the metals co., Inc. is a deep-sea minerals exploration company focused on the collection and processing of polymetallic nodules found on the seafloor in international waters of the Clarion Clipperton Zone in the Pacific Ocean (CCZ). These nodules contain high grades of four metals (nickel, copper, cobalt, manganese) which can be used as (i) feedstock for battery cathode precursors (nickel, cobalt and manganese sulfates, or intermediate nickel-copper-cobalt matte) for electric vehicles (EV) and renewable energy storage markets, (ii) copper cathode for EV wiring, energy transmission and other applications and (iii) manganese silicate for manganese alloy production required for steel production. The company was founded in 2021 and is headquartered in Vancouver, Canada.

TMC the metals company Inc

TMC is trending as the stock approaches its 52-week high, fueled by speculation around government partnerships and potential short squeezes. Community members are actively discussing cup and handle formations, awaiting news catalysts, and comparing TMC's potential to other deep sea mining and critical mineral stocks. The overall sentiment is bullish, with many anticipating a significant price increase upon positive developments.

AppLovin Corp. engages in the development and operation of a mobile marketing platform. It offers AppDiscovery, MAX, Adjust, and SparkLabs. Its software-based platform caters to mobile application developers to improve the marketing and monetization of applications. The company was founded by Andrew Karam, John Krystynak, and Adam Foroughi in 2011 and is headquartered in Palo Alto, CA.

Applovin Corp - Ordinary Shares - Class A

Applovin Corp

AppLovin ($APP) is trending due to reports of an SEC probe into its data collection practices, sparking concerns about potential regulatory violations. The community is debating the severity of the probe, with some viewing it as a buying opportunity while others anticipate further downside. This news follows a period of significant growth for AppLovin, adding to the intensity of the discussion.

DraftKings, Inc. is a digital sports entertainment and gaming company, which engages in the provision of online sports betting, online casino, daily fantasy sports product offerings, DraftKings Marketplace, retail sportsbook, media, and other consumer product offerings. The company was founded by Jason D. Robins, Matthew Kalish, and Paul Liberman on December 31, 2011 and is headquartered in Boston, MA.

DraftKings Inc. - Ordinary Shares - Class A

DraftKings Inc

DKNG is trending downwards amid concerns about increased competition from prediction markets like Kalshi and Robinhood, which are impacting investor sentiment. The community is debating the long-term effects of these platforms and whether DraftKings can adapt and maintain its market share. Some investors are calling for stronger leadership and communication from the CEO to address these challenges and instill confidence.

Figma, Inc. is an AI-powered design platform that enables seamless collaboration across the entire product development lifecycle. Its products include FigJam, Figma Slides, Figma Design, Figma Draw, Dev Mode, Figma Sites, Figma Buzz and Figma Make. The company was founded by Dylan Joseph Field and Evan Darrow Wallace in 2012 and is headquartered in San Francisco, CA.

Figma Inc. - Ordinary Shares - Class A

Figma

Figma's stock is trending after OpenAI CEO Sam Altman touted ChatGPT integration, sparking optimism about the platform's AI-powered future. The community is actively discussing the potential for increased adoption and use cases, with some eyeing ambitious price targets. However, concerns remain around margin and competition within the sector.

PayPal Holdings, Inc. engages in the development of technology platforms that enable digital payments and simplifies commerce experiences on behalf of merchants and consumers worldwide. Its solutions include PayPal, PayPal Credit, Braintree, Venmo, Xoom, and Paydiant products. The firm also enables consumers to exchange funds with merchants using funding sources, which include bank account, PayPal account balance, PayPal Credit account, credit, and debit card or other stored value products. It operates through United States and Other Countries geographical segments. The company was founded in December 1998 and is headquartered in San Jose, CA.

PayPal Holdings Inc

PayPal is experiencing increased attention as investors analyze the implications of its new Ads Manager for small businesses and a partnership with India's UPI. The community is speculating about potential analyst upgrades and the significance of connecting with India's expanding digital economy. Some traders are noting technical patterns, such as a rounded bottom, suggesting a possible breakout.

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$SGMO 

Just something I&#39;ve wondered about. A gene therapy should have much longer patent protection/ exclusivity, because it&#39;s much harder to produce a so called generic version, if not near imposible even actually?

Ran Chat GPT on this.

Yes — gene therapies are much harder to make a generic (or “biosimilar”) version of compared to traditional small-molecule drugs. Here’s why:

🧬 1. Complexity of the Product

Small-molecule drugs (like aspirin or statins) are chemically simple and can be exactly replicated. Generic manufacturers just need to prove their version is chemically identical.

Gene therapies, on the other hand, involve large, biologically active molecules (e.g., viral vectors carrying genetic payloads). These are produced in living cells, so it’s virtually impossible to make an exact copy — only something “highly similar.”

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Sangamo Therapeutics Inc

 

Just something I've wondered about. A gene therapy should have much longer patent protection/ exclusivity, because it's much harder to produce a so called generic version, if not near imposible even actually?

Ran Chat GPT on this.

Yes — gene therapies are much harder to make a generic (or “biosimilar”) version of compared to traditional small-molecule drugs. Here’s why:

🧬 1. Complexity of the Product

Small-molecule drugs (like aspirin or statins) are chemically simple and can be exactly replicated. Generic manufacturers just need to prove their version is chemically identical.

Gene therapies, on the other hand, involve large, biologically active molecules (e.g., viral vectors carrying genetic payloads). These are produced in living cells, so it’s virtually impossible to make an exact copy — only something “highly similar.”