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Churchill Capital Corp. X is a blank check company, which was created for the purpose of effecting a merger, capital stock exchange, asset acquisition, stock purchase, reorganization, or similar business combination with one or more businesses. The company was founded by Michael Klein on January 4, 2024 and is headquartered in New York, NY.

Infleqtion Inc. - Ordinary Shares - Class A

Infleqtion Inc.

Infleqtion Inc. ($INFQ) is trending as it begins trading under its new ticker after a de-SPAC merger, with the community actively discussing its strong quantum technology fundamentals, low share float, and significant growth potential despite current volatile market conditions and some brokerage update delays.

Ocular Therapeutix, Inc. is a biopharmaceutical company, which engages in the development and commercialization of therapies for diseases and conditions of the eye. Its product pipeline includes Dextenza, OTX-TP, and OTX-TIC. The company was founded by Amarpreet S. Sawhney and Farhad Khosravi on September 12, 2006 and is headquartered in Bedford, MA.

Ocular Therapeutix Inc

Ocular Therapeutix is drawing attention after announcing positive topline Phase 3 results for its wet AMD treatment, AXPAXLI, demonstrating superiority and durability over a comparator; yet, the stock's unexpected decline has fueled community discussions on market manipulation, the drug's commercial competitive edge, and persistent buyout speculation.

Compass Pathways Plc is a biotechnology company, which provides mental health care services. It focuses on improving the lives of those who are suffering with mental health challenges and who are not helped by current treatments. The company was founded by Goldsmith George Jay and Malievskaia Ekaterina in 2016 and is headquartered in London, the United Kingdom.

Compass Pathways Plc - ADR

COMPASS Pathways

COMPASS Pathways is experiencing significant momentum following positive Phase 3 trial results for its COMP360 psilocybin therapy in treatment-resistant depression, which demonstrated rapid, sustained efficacy and a favorable safety profile. The community is now buzzing about the accelerated timeline for a potential commercial launch and a newly cleared FDA path for PTSD trials, seeing this as a major step towards becoming a first-to-market psychedelic medicine.

Velo3D, Inc. operates as a technology company, which engages in developing and manufacturing metal laser sintering printing machines for 3D printing. Its products include assure system, flow software, sapphire printer & sapphire XC. The company was founded by Benyamin Buller in June 2014 and is headquartered in Fremont, CA.

Velo3D Inc

Velo3D is generating significant discussion after securing an $11.5 million full-rate production defense contract and being selected as the U.S. Army's first qualified additive manufacturing vendor for ground vehicle systems. While these defense wins and ongoing partnerships with SpaceX and Anduril excite many about its critical role in advanced manufacturing, the community is also actively debating recent share dilution as a factor in near-term price volatility.

ZIM Integrated Shipping Services Ltd. engages in the provision of shipping and logistics services. It offers shipping solutions, including the transportation of out-of-gauge cargo, refrigerated cargo, and dangerous and hazardous cargo. The company was founded on June 7, 1945 and is headquartered in Haifa, Israel.

Zim Integrated Shipping Services Ltd

ZIM Integrated Shipping Services is trending following its signed acquisition agreement by Hapag-Lloyd for $35 per share, creating significant arbitrage buzz and expectations for a short squeeze. The community is actively discussing the deal's valuation, geopolitical approval, and the anticipation of continued dividend payments until the late 2026 closing.

JFB Construction Holdings is a commercial and residential real estate construction and development company, which engages in delivering services to commercial and residential markets. It operates through the following segments: Commercial Construction, Residential Construction, and Real Estate Development. The Commercial Construction segment includes all activities related to the construction of commercial properties. The Residential Construction segment focuses on the construction of residential properties including single-family homes and multi-family units. The Real Estate Development segment refers to the acquisition, development, and sale of real estate properties. The company was founded by Joseph F. Basille III on April 9, 2024 and is headquartered in Lantana, FL.

JFB Construction Holdings - Ordinary Shares - Class A

JFB Construction Holdings is trending due to its transformative $1.5 billion business combination with AI-driven autonomous defense robotics company Xtend, signaling a major strategic pivot from its traditional construction focus. This significant shift is sparking intense community discussion, with some investors bullish on high-growth potential while others express concerns over extreme volatility and recent dilution from a private placement.

The Wendy’s Co. engages in operating, developing, and franchising a system of quick-service restaurants. It operates through the following segments: Wendy’s U.S., Wendy’s International, and Global Real Estate and Development. The Wendy’s U.S. segment includes the operation and franchising of Wendy’s restaurants in the U.S. The Wendy’s International segment is involved in the operation and franchising of Wendy’s restaurants in countries and territories other than the U.S. The Global Real Estate and Development segment focuses on real estate activity for owned sites and sites leased from third parties. The company was founded by R. David Thomas on November 15, 1969 and is headquartered in Dublin, OH.

Wendy`s Co - Ordinary Shares - Class A

Wendy's Co

Wendy's is trending following its Q4 earnings and weak 2026 guidance, which led to analyst downgrades and a sharp stock decline. The community is fiercely debating the future, with bears focused on declining US sales and high debt, while bulls highlight deep undervaluation, a strong dividend yield, and turnaround potential.

Federal National Mortgage Association is a government-sponsored company, which engages in the provision of liquidity for purchases of homes and financing of multifamily rental housing and refinancing existing mortgages. It operates through the Single-Family and Multifamily segments. The Single-Family segment offers liquidity to the mortgage market and increases the availability and affordability of housing for single families. The Multifamily segment includes guaranty fees on mortgages and on multifamily mortgage loans. The company was founded in 1938 and is headquartered in Washington, DC.

Federal National Mortgage Association

Federal National Mortgage Association (FNMA) is trending as its strong Q4 earnings and ongoing political discussions, including recent congressional efforts and conflicting statements from FHFA Director Pulte regarding a potential IPO or release from conservatorship, create a volatile environment, leaving investors torn between optimism for significant gains and frustration over continued uncertainty and price fluctuations.

Palo Alto Networks, Inc. engages in the provision of network security solutions to enterprises, service providers, and government entities. It operates through the following geographical segments: the United States, Israel, and Other Countries. The company was founded by Nir Zuk in March 2005 and is headquartered in Santa Clara, CA.

Palo Alto Networks Inc

Palo Alto Networks is trending as investors digest its recent earnings and strategic acquisitions of Chronosphere and CyberArk, fueling a divisive community debate on its high valuation and the cybersecurity sector's future amidst broader AI-driven software concerns.

Medtronic Plc is a medical technology company, which engages in the development, manufacture, distribution, and sale of device-based medical therapies and services. It operates through the following segments: Cardiovascular Porrtfolio, Neuroscience Portfolio, Medical Surgical Portfolio, and Diabetes Operating Unit. The Cardiovascular Portfolio segment includes products for the diagnosis, treatment, and management of cardiac rhythm disorders and cardiovascular disease. The Neuroscience Portfolio is made up of cranial and spinal technologies, specialty therapies, and neuromodulation divisions. The Medical Surgical Portfolio is comprised of surgical innovations and respiratory, gastrointestinal, and renal divisions. The Diabetes Group segment offers insulin pumps, continuous glucose monitoring systems, and insulin pump consumables. The company was founded in 1949 and is headquartered in Dublin, Ireland.

Medtronic Plc

Medtronic is trending following its recent earnings report, where a beat on top and bottom lines was overshadowed by softer guidance and margin concerns, leading to a stock dip. Community discussion is also focused on the strategic plan to spin off its diabetes business, coupled with a series of new FDA clearances for advanced medical devices, signaling a potential shift towards higher-growth segments.

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 Hey, I want to invite you to join Stocktwits. It’s the largest global community of active traders. You’ll get access to the real-time market insights, news, discussion and much more! You can sign up using my unique link below 
 


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$SGMO Looking at the chart below more closely, I decided to take just one of the genes mentioned -- SCN2A -- and  do  little bit more research. SCN2A mutation leads to infantile epileptic encephalopathy (IIE) and/or also to autism/developmental delay.  Therapy for IIE is to downregulate SCN2A and for autism, upregulate it. 
 
The problem with currently considered approaches such as using anti-sense oligonucleotides (ASOs) to regulate the gene is that they don&#39;t get deeply enough into the brain structures to have the desired effect. Here&#39;s a question directly on point during a fantastic presentation on this subject from 2021 by Dr. Stephan Sanders.  https://youtu.be/yGvdVMzXHLs?t=1460 (24:20 in the video).  
 
So right away I can see an application for STAC-BBB here in its brain-penetrating abilities. Interestingly, Dr. Sanders&#39; work (at least in 2021) was sponsored by BioMarin ($BMRN). Wouldn&#39;t it be ironic if the competitor to $SGMO&#39;s hem A drug is also a partner in a STAC-BBB deal?

Ding Dong

William S Burroughs

JimiJo Jeeter

Nainggolan

G. Hopper

IberianBullish

Franca

biotech

Gregory Smock

UCSF is a leading center for SCN2A research. Learn about their work specific to CRISPRa / AAV and about how gene therapy in general can work for #SCN2A.

YouTube

RX: Hope Table Talk Session #5 "Gene Therapy Techniques (AAV and CRISPRa) for SCN2A"

$SGMO As we sip our post-market beverages on this inauspicious market day, let&#39;s remind ourselves what STAC-BBB targets have not yet been, but may well be soon, monetized by SGMO in another capsid deal ... this slide from their last earnings call presentation ...

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Sangamo Therapeutics Inc

Herr Chicken

Biomarin Pharmaceutical Inc. - Registered Shares

 Looking at the chart below more closely, I decided to take just one of the genes mentioned -- SCN2A -- and  do  little bit more research. SCN2A mutation leads to infantile epileptic encephalopathy (IIE) and/or also to autism/developmental delay.  Therapy for IIE is to downregulate SCN2A and for autism, upregulate it. 
 
The problem with currently considered approaches such as using anti-sense oligonucleotides (ASOs) to regulate the gene is that they don't get deeply enough into the brain structures to have the desired effect. Here's a question directly on point during a fantastic presentation on this subject from 2021 by Dr. Stephan Sanders.  

 (24:20 in the video).  
 
So right away I can see an application for STAC-BBB here in its brain-penetrating abilities. Interestingly, Dr. Sanders' work (at least in 2021) was sponsored by BioMarin (