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Spruce Biosciences, Inc. is a biopharmaceutical company, which engages in developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical need. The company was founded on November 13, 2014 and is headquartered in South San Francisco, CA.

Spruce Biosciences Inc

SPRB is trending due to a significant surge following positive trial results and the FDA granting Breakthrough Therapy Designation for its Sanfilippo syndrome type B treatment. Community discussions revolve around the potential for continued upward momentum, comparisons to other high-flying stocks, and the possibility of a substantial correction. Some traders are eyeing similar setups in other low-float biotech companies, while others caution against chasing the rally.

Siyata Mobile, Inc. engages in the provision of cellular communications systems for enterprise customers. It specializes in connected vehicle products for professional fleets, marketed under the Uniden Cellular and Siyata brands. The firm operates through the following geographical segments: Europe, the Middle East and Africa; Unites States; Canada; and Australia and New Zealand. The company was founded by Marc Seelenfreund on October 15, 1986 and is headquartered in Montreal, Canada.

Core AI Holdings Inc.

Core AI Holdings, Inc.

Core AI Holdings ($CHAI), formerly Siyata Mobile, is trending as the merger with Core Gaming is finalized, with trading to commence under the new $CHAI ticker soon. Community members are actively discussing the potential impact of the reverse stock split and the company's new focus on AI-driven mobile gaming, some drawing comparisons to other AI stocks. Some users are also expressing concerns about potential delays in trading on certain platforms.

PayPal Holdings, Inc. engages in the development of technology platforms that enable digital payments and simplifies commerce experiences on behalf of merchants and consumers worldwide. Its solutions include PayPal, PayPal Credit, Braintree, Venmo, Xoom, and Paydiant products. The firm also enables consumers to exchange funds with merchants using funding sources, which include bank account, PayPal account balance, PayPal Credit account, credit, and debit card or other stored value products. It operates through United States and Other Countries geographical segments. The company was founded in December 1998 and is headquartered in San Jose, CA.

PayPal Holdings Inc

PayPal is experiencing increased attention as investors analyze the implications of its new Ads Manager for small businesses and a partnership with India's UPI. The community is speculating about potential analyst upgrades and the significance of connecting with India's expanding digital economy. Some traders are noting technical patterns, such as a rounded bottom, suggesting a possible breakout.

Archer Aviation, Inc. engages in the development of electric vertical take-off and landing (eVTOL) aircraft. The company was founded by Brett Adcock and Adam Goldstein on October 16, 2018, and is headquartered in San Jose, CA.

Archer Aviation Inc - Ordinary Shares - Class A

Archer Aviation Inc

Archer Aviation ($ACHR) is trending amid speculation of a partnership with Tesla ($TSLA), fueled by a teaser video and shared appearances at a summit, though analysts anticipate Tesla's announcement may focus on a new, lower-priced vehicle. Community members are actively debating the validity of the rumors and potential impact on $ACHR, while some highlight existing partnerships and catalysts independent of Tesla. Bullish investors are anticipating a potential short squeeze, with some setting price targets significantly higher.

AppLovin Corp. engages in the development and operation of a mobile marketing platform. It offers AppDiscovery, MAX, Adjust, and SparkLabs. Its software-based platform caters to mobile application developers to improve the marketing and monetization of applications. The company was founded by Andrew Karam, John Krystynak, and Adam Foroughi in 2011 and is headquartered in Palo Alto, CA.

Applovin Corp - Ordinary Shares - Class A

Applovin Corp

AppLovin ($APP) is trending amidst reports of an SEC probe into its data collection practices, sparking a selloff and active debate among investors. While some view the dip as a buying opportunity, citing strong fundamentals and analyst support, others are concerned about potential risks and regulatory headwinds. The community is closely monitoring the situation, with discussions ranging from short-term trading strategies to long-term implications for the ad-tech sector.

Galecto, Inc. is a clinical-stage biotechnology company, which engages in developing novel small molecule therapeutics that are designed to target the biological processes that lie at the heart of cancer and fibrotic diseases. The firm is also involved in the development of small molecule inhibitors of galectin-3 and LOXL2. The company was founded by Ulf Jörgen Nilsson, Hakon Leffler, Tariq Sethi, and Hans Thalsgård Schambye in 2011 and is headquartered in Boston, MA.

Galecto Inc

GLTO is experiencing significant interest and volatility, with community members discussing potential halts and price targets, possibly fueled by momentum similar to other recent runners. The stock's low float and potential for a squeeze are key discussion points, with some comparing it to previous high-flying stocks. Chatter also mentions potential news or catalysts that could be driving the price action, though nothing is confirmed.

HIVE Digital Technologies Ltd. engages in building a bridge between the digital currency and blockchain sector and traditional capital markets. It operates data centers for computing and mining cryptocurrencies, including Bitcoin and other coins. The firm owns and operates green energy-powered data center facilities in Canada, Sweden, and Iceland. Its project includes Iceland Cryptocurrency Mining. HIVE Digital Technologies was founded on June 24, 1987 and is headquartered in San Antonio, TX.

HIVE Digital Technologies Ltd.

HIVE Digital Technologies Ltd

HIVE Digital Technologies is trending due to its recent Bitcoin production surge and expansions into AI cloud services, with community members eyeing previous highs. Investors are optimistic about HIVE's strategic positioning, including its Paraguay site and Toronto data center, as Bitcoin prices rally. Bullish sentiment is further fueled by comparisons to peers and potential for significant growth in the HPC/AI sectors.

Trilogy Metals, Inc. engages in the development and exploration of mineral properties. The firm holds interests in the Upper Kobuk mineral projects that include the Arctic, a copper-zinc-lead-gold-silver and Bornite, a carbonate-hosted copper projects, which is located in the Ambler mining district in Northwest Alaska. The company was founded on April 27, 2011 and is headquartered in Vancouver, Canada.

Trilogy Metals Inc

TMQ is trending following news that the U.S. government will take a 10% stake in the company to support mining exploration in Alaska. The community is discussing the potential for a short squeeze and the stock's potential to reach double digits, while some express caution about a possible sell-off or secondary offering. The move aligns with broader efforts to secure domestic mineral resources.

Advanced Micro Devices, Inc. engages in the provision of semiconductor businesses. It operates through the following segments: Data Center, Client, Gaming, and Embedded. The Data Center segment includes server-class CPUs, GPUs, AI accelerators, DPUs, FPGAs, SmartNICs, and Adaptive SoC products. The Client segment refers to the computing platforms, which are a collection of technologies that are designed to work together to provide a more complete computing solution. The Gaming segment is a fundamental component across many products and can be found in APU, GPU, SoC or a combination of a discrete GPU with another product working in tandem. The Embedded segment focuses on the embedded CPUs, GPUs, APUs, FPGAs, and Adaptive SoC products. The company was founded by W. J. Sanders III on May 1, 1969 and is headquartered in Santa Clara, CA.

Advanced Micro Devices Inc.

Advanced Micro Devices Inc

Advanced Micro Devices is trending following news of a major AI partnership with OpenAI, which includes significant GPU hardware commitments and stock warrants. The community is focused on the potential long-term impact of this deal on AMD's revenue and market share, with some analysts raising price targets substantially. Discussions also involve the competitive landscape and AMD's positioning relative to Nvidia in the AI space.

Critical Metals Corp. engages in the mining, exploration, and development of lithium metals. It owns Wolfsberg Project and Tanbreez Project. The company was founded on October 24, 2022 and is headquartered in British Virgin Islands.

Critical Metals Corp.

CRML is trending as the community discusses its potential in the critical minerals sector, particularly regarding a possible U.S. government stake in the Greenland project. Community members are debating the validity and implications of recent news reports, with some suggesting market manipulation and others remaining bullish on the company's long-term prospects amid rising demand for rare earth elements. Discussions also involve the company's financials, strategic partnerships, and potential for future growth under the Trump administration's focus on domestic mining.

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$CRIS At #DAVAGI, Dr. Kian Lim from @SitemanCenter spotlights IRAK4 as a novel target in GI cancers. Early trial of CA-4948 + FOLFOX + PD-1 (± trastuzumab) in gastric/GEJ cancer shows 1 CR (25mo), multiple PR/SD, with no added high-grade toxicity. A promising new strategy!

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Curis Inc

, Dr. Kian Lim from @SitemanCenter spotlights IRAK4 as a novel target in GI cancers. Early trial of CA-4948 + FOLFOX + PD-1 (± trastuzumab) in gastric/GEJ cancer shows 1 CR (25mo), multiple PR/SD, with no added high-grade toxicity. A promising new strategy!

Fred Jupiter

@MaiXin @SitemanCenter link to where this was pulled from?

 @SitemanCenter link to where this was pulled from?

https://x.com/DAVAOnc/status/1968990490386206776

At #DAVAGI, Dr. Kian Lim from @SitemanCenter spotlights IRAK4 as a novel target in GI cancers. Early trial of CA-4948 + FOLFOX + PD-1 (± trastuzumab) in gastric/GEJ cancer shows 1 CR (25mo), multiple PR/SD, with no added high-grade toxicity. A promising new strategy! pic.twitter.com/p2C9DWghtb

X (Formerly Twitter)

DAVA Oncology on X (formerly Twitter): "At #DAVAGI, Dr. Kian Lim from @SitemanCenter spotlights IRAK4 as a novel target in GI cancers. Early trial of CA-4948 + FOLFOX + PD-1 (± trastuzumab) in gastric/GEJ cancer shows 1 CR (25mo), multiple PR/SD, with ...