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Intuitive Machines, Inc. is a space exploration, infrastructure, and services company, which engages in contributing to the establishment of cislunar infrastructure and helping to develop cislunar and deep space commerce. It offers space products and services. The company was founded by Stephen J. Altemus, Kam Ghaffarian, and Timothy P. Crain in 2013 and is headquartered in Houston, TX.

Intuitive Machines Inc - Ordinary Shares - Class A

Intuitive Machines Inc

Intuitive Machines (LUNR) is trending amidst investor debate over a recent $175 million strategic investment that triggered share dilution, leading many to see a "buy the dip" opportunity while others anticipate further declines. Community conversation is heavily focused on the impending NASA Lunar Terrain Vehicle (LTV) contract award and upcoming earnings, which are shaping sentiment regarding the company's long-term position in the evolving space economy.

Circle Internet Group, Inc. is a financial technology company that enables businesses of all sizes to harness the power of digital currencies and public blockchains for payments, commerce and financial applications worldwide. The company was founded by Jeremy J. Allaire and Patrick Sean Neville in August 2013 and is headquartered in New York, NY.

Circle Internet Group Inc. - Ordinary Shares - Class A

Circle

Circle (CRCL) is trending following a significant Q4 earnings beat and a surge in USDC adoption, which is fueling investor speculation about a potential short squeeze. Meanwhile, the community is actively debating the company's future, weighing bullish long-term potential as a digital asset platform against bearish concerns around dilution, regulatory uncertainty (like the Clarity Act), and sensitivity to interest rates.

NVIDIA Corp. engages in the design and manufacture of computer graphics processors, chipsets, and related multimedia software. It operates through the following segments: Graphics Processing Unit (GPU) and Compute & Networking. The Graphics segment includes GeForce GPUs for gaming and PCs, the GeForce NOW game streaming service and related infrastructure, Quadro and NVIDIA RTX GPUs for enterprise workstation graphics, virtual GPU, or vGPU, software for cloud-based visual and virtual computing, automotive platforms for infotainment systems, and Omniverse Enterprise software for building and operating metaverse and 3D internet applications. The Compute & Networking segment consists of Data Center accelerated computing platforms and end-to-end networking platforms including Quantum for InfiniBand and Spectrum for Ethernet, NVIDIA DRIVE automated-driving platform and automotive development agreements, Jetson robotics and other embedded platforms, NVIDIA AI Enterprise and other software, and DGX Cloud software and services. The company was founded by Jen Hsun Huang, Chris A. Malachowsky, and Curtis R. Priem in April 1993 and is headquartered in Santa Clara, CA.

NVIDIA Corp

NVIDIA is trending as the market anticipates its pivotal Q4 earnings report, with sentiment sharply divided between expectations of a blowout performance driving new highs and concerns over a potential "sell the news" event. Discussions are also active around the future of AI demand, competition, and the upcoming Rubin AI system.

Trump Media & Technology Group Corp. engages in operating social media and in the technology business. Its brands include TRUTH Social, TMTG+ and TMTG News. The company was founded on March 28, 2024 and is headquartered in Sarasota, FL.

Trump Media & Technology Group Corp.

DJT is trending due to highly polarized reactions to Donald Trump's recent State of the Union address, where community discussion is intensely divided over his political rhetoric, economic claims, and controversy surrounding the Epstein files; this has investors and commentators sharply split between those celebrating the speech as a success that will drive the stock and those criticizing it as a "lie-a-thon" underscoring the company's speculative fundamentals.

Zeta Global Holdings Corp. operates as a marketing technology software company, which engages in the provision of enterprises with consumer intelligence and marketing automation software. It enables its customers to target, connect and engage consumers through software that delivers marketing across all addressable channels, including email, social media, web chat, connected TV and video among others. The company was founded by David A. Steinberg and John Sculley on May 9, 2012 and is headquartered in New York, NY.

Zeta Global Holdings Corp - Ordinary Shares - Class A

Zeta Global Holdings Corp

Zeta Global is trending following its earnings report, which highlighted its consistent "beat and raise" streak and AI-powered marketing platform's strong performance, sparking community discussion about its undervalued position despite ongoing software sector sell-offs.

SoundHound AI, Inc. engages in the development, owning, and commercialization of voice, sound, and natural language artificial intelligence technologies and related activities. The company was founded on September 2, 2005 and is headquartered in Santa Clara, CA.

SoundHound AI Inc - Ordinary Shares - Class A

SoundHound AI Inc

SoundHound AI is trending following recent announcements of an innovation hub in India and a new "Sales Assist" agent, all ahead of its highly anticipated earnings report. Community discussion is focused on strong expectations for revenue growth and a path to profitability, with high short interest fueling speculation of a potential squeeze for its patented voice AI technology across automotive, QSR, and enterprise sectors.

Oddity Tech Ltd. engages in the online retail sale of cosmetics and beauty products. Its products include lipsticks, makeup brushes, mascara, eyelash curlers, and makeup brush cleansers. The company was founded by Oran Holtzman and Shiran Holtzman-Erel on March 23, 2013 and is headquartered in Tel Aviv, Israel.

ODDITY Tech Ltd. - Ordinary Shares - Class A

A controversial short report alleging ODDITY engaged in business misrepresentation and dishonest marketing has sparked fierce debate, with many investors buying the dip on strong fundamentals, a newly announced share buyback program, and a perceived overreaction, while others foresee further declines amid claims of fraud and overvaluation.

Lucid Group, Inc. manufactures electric vehicles. It designs, develops, and builds energy storage systems for electric vehicles and supplies automakers with the battery pack system needed to power hybrid, plug-in, and electric vehicles. The company was founded in December 2007 and is headquartered in Newark, CA.

Lucid Group Inc

Lucid Group is trending due to a mixed earnings report showing revenue growth alongside widening losses and significant cash burn, fueling community debate over its future amid recent workforce reductions, ongoing dilution concerns from a large share resale, and a prolonged search for a permanent CEO. Investors are closely watching for clarity on its path to profitability, particularly concerning upcoming models and plans to be presented at its Investor Day.

Workday, Inc. engages in the provision of development of enterprise cloud applications for finance and human resources. It delivers financial management, human capital management and analytics applications designed for companies, educational institutions, and government agencies. The company was founded by David A. Duffield and Aneel Bhusri in 2005 and is headquartered in Pleasanton, CA.

Workday Inc - Ordinary Shares - Class A

Workday Inc

Workday is trending down sharply after its latest earnings report, despite beating EPS and revenue estimates, as cautious fiscal year 2027 revenue guidance amplifies broader market concerns about AI's disruptive impact on the software sector. The community is actively debating if the current sell-off is an overreaction to strong underlying fundamentals or a justified repricing given the evolving landscape.

Cava Group, Inc. is a holding company, which engages in the category-defining Mediterranean fast-casual restaurant brand, bringing together healthful food and bold, satisfying flavors at scale. It operates through the following segments: CAVA and CAVA Foods. The CAVA segment includes the operations of all company-owned CAVA restaurants. The CAVA Foods segment includes the production of dips and spreads used in CAVA restaurants as well as sales from the consumer-packaged goods (CPG) business. The company was founded by Brett Schulman, Ike Grigoropoulus, Dimitri Moshovitis, and Theodore Xenohristos in 2010 and is headquartered in Washington, DC.

Cava Group Inc

CAVA Group Inc

CAVA Group is surging after reporting strong Q4 revenue and same-store sales that exceeded expectations, coupled with an optimistic outlook for new locations and 2026 growth. This performance is fueling intense community discussion, with bulls touting its long-term potential as a category leader, while skeptics continue to question its high valuation metrics.

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$OKUR https://www.youtube.com/watch?v=7R-wvMDgdsY Listen to the first halve of this, very interesting. A presentation of data from PI3K inhibitors from SABCS 2024 and later they discuss the data.  
Take away from this: 
-its a promising target 
-you have to hit the target very hard  
-you need high selectivity to hit it hard, otherwise issues with tolerability, which leads to dose reductions or discontinuations 
-you need great safety, because patients have to potentially be on drug for years 
-single agent PI3K inhibition doesnt make much sense due to low efficacy, but in combination with fulvestrant it really shines.  
- ctDNA reduction correlates with responses

George G

This session took place at 7a.m. Wednesday, Dec. 11, 2024. It was a Poster Spotlight session. YOUTUBE CHAPTERS 0:00 Introduction by moderator Shom Goel, from the Peter MacCallum Cancer Centre in Melbourne, Australia 1:28 Discussant Chris Vaklavas of the Huntsman Cancer Institute in Salt Lake City, Utah. Discussing posters PS7-01 through PS7-04.

YouTube

SABCS 2024: Targeting the ER and PI3K pathway - novel drugs and combinations

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Onkure Therapeutics Inc

 Listen to the first halve of this, very interesting. A presentation of data from PI3K inhibitors from SABCS 2024 and later they discuss the data.  
Take away from this: 
-its a promising target 
-you have to hit the target very hard  
-you need high selectivity to hit it hard, otherwise issues with tolerability, which leads to dose reductions or discontinuations 
-you need great safety, because patients have to potentially be on drug for years 
-single agent PI3K inhibition doesnt make much sense due to low efficacy, but in combination with fulvestrant it really shines.  
- ctDNA reduction correlates with responses