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Bitcoin is the world's first decentralized cryptocurrency, created in 2009 by the pseudonymous Satoshi Nakamoto. It enables peer-to-peer electronic cash transactions without intermediaries like banks or governments, operating on a blockchain secured by Proof of Work mining and the SHA-256 cryptographic algorithm.   With a fixed supply cap of 21 million coins and programmatic halvings every four years that reduce miner rewards, Bitcoin is designed as a deflationary digital asset often called "digital gold." Its value stems from solving the double-spending problem without trusted intermediaries, creating the first truly scarce digital asset with censorship resistance and permissionless access that no government, corporation, or individual can control.  Bitcoin operates as a decentralized peer-to-peer network where transactions are recorded on a public ledger called the blockchain, distributed across thousands of computers globally. Transactions are grouped into blocks added approximately every 10 minutes through mining, where specialized computers compete to solve complex mathematical puzzles.   Bitcoin has achieved mainstream adoption through multiple vectors. The January 2024 SEC approval of 11 spot Bitcoin ETFs opened Bitcoin investment to traditional finance participants, and corporations like Strategy (formerly MicroStrategy) are using Bitcoin as a treasury reserve asset to protect against currency debasement, offering MSTR holders amplified exposure to Bitcoin.   The Bitcoin ecosystem continues to evolve with innovations like Ordinals, which emerged in January 2023 to enable NFT-like functionality directly on Bitcoin, and BRC-20 tokens, an experimental standard for creating fungible tokens using Ordinal inscriptions. BTCFi (Bitcoin Finance) represents emerging financial applications extending beyond Bitcoin's traditional role, with protocols like Babylon allowing Bitcoin holders to stake BTC to secure Proof of Stake chains.

Bitcoin

Bitcoin's breakout above long-standing resistance to its highest level since January is dominating the conversation, with traders citing heavy short liquidations and a weekly close above the 50-week moving average as bullish confirmation. Bulls are declaring the bear market over while skeptics warn of a bull trap, manipulation, or profit-taking, with some attributing the rally to an SEC tokenization push and others noting it came despite the Senate blocking the Clarity Act.

Strategy, Inc. engages in the development of fixed-income instruments that provide investors varying degrees of economic exposure to bitcoin. It executes bitcoin acquisition, capital management, and capital markets strategies. The company was founded by Michael J. Saylor and Sanjeev K. Bansal on November 17, 1989, and is headquartered in Tysons Corner, VA.

Strategy Inc. - Ordinary Shares - Class A

Strategy

MSTR is trending after a sharp rally that tracked bitcoin's surge to its highest level since January, reinforced by a regulatory filing confirming the purchase of 950 additional bitcoin and no ATM share sales during the period. Community reaction is split between bulls gloating over trapped shorts and framing the move as a squeeze, and skeptics calling it overextended, citing dilution risk and the stock trading at a premium to its bitcoin holdings.

Critical Metals Corp. engages in the mining, exploration, and development of lithium metals. It owns Wolfsberg Project and Tanbreez Project. The company was founded on October 24, 2022 and is headquartered in British Virgin Islands.

Critical Metals Corp.

CRML is surging alongside other Greenland-linked rare earth names after Trump announced a U.S.-Denmark-Greenland security agreement granting Washington permanent security access to the island and authority to block sensitive investments by adversaries. Discussion is heavily bullish, with elevated short interest fueling squeeze speculation, while skeptics argue the pact is a security arrangement that does not change mining rights, and some traders debate whether critical minerals are on the agenda at the upcoming Trump-Xi summit in ways that could strengthen or undercut the domestic rare earth thesis.

XRP is a decentralized digital asset and the native token of the XRP Ledger, a Layer 1 blockchain designed for high-performance global payments. Its primary value proposition is offering a fast, cost-effective alternative to traditional banking systems by enabling near-instant cross-border settlements that finalize in three to five seconds. By serving as a neutral bridge asset between different fiat currencies, it helps financial institutions lower liquidity costs and eliminates the need for pre-funded accounts.  The network is unique because it utilizes a federated consensus protocol instead of energy-intensive mining or staking. This system achieves deterministic finality through a Unique Node List of trusted validators who must reach an eighty percent agreement threshold to permanently record transactions. This infrastructure supports a sustained throughput of 1,500 transactions per second and includes a built-in decentralized exchange that allows for the automated trading of any tokenized asset without intermediaries.  The project traces its origins back to 2004 with Ryan Fugger before being co-founded in its modern form by Jed McCaleb and Chris Larsen. The company, now known as Ripple, works with major financial institutions as partners and investors to build global payment solutions. To protect the network from spam, a small amount of XRP is burned during every transaction, and the token is further utilized by institutions as collateral to access traditional markets and manage digital asset infrastructure.  Institutional adoption of the asset reached a major milestone in November 2025 when the SEC approved the first wave of spot XRP ETFs. These products, offered by major issuers including Bitwise, Grayscale, 21Shares, Canary Capital, and Franklin Templeton, are now listed on prominent exchanges like the NYSE Arca, Nasdaq, and Cboe BZX. While Ripple remains a key contributor to the ecosystem, the underlying XRP Ledger continues to operate as an open-source and decentralized network.

Ripple

XRP's sharp rebound toward a long-capped resistance level is dominating the conversation, with traders citing the CFTC sending draft crypto market rules to the White House and SEC rulemaking after the Clarity Act's failed Senate vote as the driver. The community is split over whether the move is a genuine breakout or merely a short squeeze, with skeptics pointing to Bitcoin-linked price action and heavy token supply while bulls cite whale accumulation and short liquidations.

Ethereum is a global, open-source platform for decentralized applications. In other words, it is a decentralized blockchain platform that enables developers to build and deploy smart contracts and applications without central authority control. Unlike Bitcoin, which primarily functions as digital currency, Ethereum operates as a programmable global computer where developers can create any type of decentralized service.   The platform hosts over $14 billion in DeFi applications with hundreds of thousands of active users across financial protocols, NFT marketplaces, and gaming platforms. Its transition to Proof of Stake in September 2022 reduced energy consumption by over 99%, addressing environmental concerns while strengthening network security.  The network operates through thousands of independent validator nodes that process transactions and execute smart contracts on the Ethereum Virtual Machine. Smart contracts are self-executing programs written in Solidity that automatically carry out agreements when conditions are met, eliminating intermediaries like banks or brokers.   Validators stake ETH as collateral to propose and validate blocks, earning rewards for honest participation while facing penalties for malicious behavior. The EIP-1559 upgrade introduced a dynamic base fee mechanism that burns ETH with each transaction, creating deflationary pressure during high network activity when more ETH is burned than issued to validators.  Vitalik Buterin proposed Ethereum in 2013, but seven co-founders helped build it, including Gavin Wood who created Solidity and the EVM technical specification, and Joseph Lubin who founded ConsenSys. The project launched in July 2015 after raising over $18 million through crowdfunding, quickly becoming the largest blockchain developer community. Major milestones include the 2020 Beacon Chain launch, the 2021 London hard fork implementing fee burning, and the 2022 Merge to Proof of Stake.   Ether (ETH) serves multiple functions: paying transaction fees (gas), staking to secure the network and earn 3-5% annual yields, serving as collateral in DeFi protocols, and purchasing NFTs and digital assets. The asset is increasingly adopted by traditional institutions, with publicly traded companies adding ETH to corporate treasuries to generate staking yields while maintaining blockchain exposure, and in 2024, the SEC approved spot Ethereum ETFs, allowing traditional investors to gain exposure through conventional brokerage accounts.  Ethereum's roadmap focuses on dramatically increasing transaction capacity to over 100,000 per second, reducing confirmation times, and enhancing decentralization while maintaining security against future threats like quantum computing.

Ethereum

Ethereum is surging in a broad crypto rally that traders attribute to heavy short liquidations and the SEC's "Innovation Exemption" allowing on-chain trading of tokenized U.S. stocks after the Clarity Act stalled, with Bitcoin reclaiming multi-month highs alongside. The community is overwhelmingly bullishcelebrating squeezed shorts and a breakout above prior resistancethough some traders warn the move could reverse on macro pressure, rate-hike fallout, or a weekend dump.

Coinbase Global, Inc. engages in the provision of a trusted platform that serves as a compliant on-ramp to the onchain economy and enables users to engage in a wide variety of activities with their crypto assets in both proprietary and third-party product experiences enabled by access to decentralized applications. It offers consumers primary financial account for the cryptoeconomy, institutions a full-service prime brokerage platform with access to deep pools of liquidity across the crypto marketplace, and developers a suite of products granting access to build onchain. The company was founded by Brian Armstrong and Fred Ernest Ehrsam in May 2012 and is headquartered in New York, NY.

Coinbase Global Inc - Ordinary Shares - Class A

Coinbase Global Inc

COIN is surging as Bitcoin rebounds toward multi-month highs, with traders weighing the SEC's five-year tokenized-stock exemption and the Senate's failure to advance the CLARITY Act  which CEO Brian Armstrong said could leave Coinbase with less competition  alongside the firm's CFTC filing for single-stock perpetual futures. Debate centers on whether the move reflects company-specific tokenization catalysts or simply crypto beta tracking Bitcoin, with bulls citing heavy short interest and bears expecting the rally to fade.

Novo Nordisk A/S is a global healthcare company, which engages in the discovery, development, manufacturing and marketing of pharmaceutical products. It operates through the Diabetes and Obesity Care and Rare Disease segments. The Diabetes and Obesity Care segment includes diabetes, obesity, cardiovascular, and emerging therapy areas. The Rare Disease segment refers to rare blood disorders, rare endocrine disorders, and hormone replacement therapy. The company was founded by Harald Pedersen and Thorvald Pedersen in 1923 is headquartered in Bagsværd, Denmark.

Novo Nordisk - ADR

Novo Nordisk A/S

Shares slid roughly 5% after Novo Nordisk's Capital Markets Day, where long-term growth and pipeline targetsincluding more than five new blockbuster launches by 2030failed to reassure investors focused on Eli Lilly's competitive lead and the looming semaglutide patent cliff. The community is divided, with critics blasting management for vague guidance and a weak presentation, contrarian bulls calling the stock oversold and buying the dip, and some traders claiming the drop was a deliberate attack rather than fundamentals-driven.

New Era Energy & Digital, Inc. is an exploration and production company, which engages in selling oil and natural gas products. The company was founded on February 6, 2023 and is headquartered in Midland, TX.

New Era Energy & Digital Inc.

New Era Energy & Digital is trending after securing a 20-year, 207 MW power purchase agreement with Vistra, a deal traders say puts the Phase 1 power contract in NUAI's own name rather than through development partner Stream. Reaction is largely bullish, with many speculating a hyperscaler tenant lease is the next catalyst, while skeptics note the company is still actively marketing for a tenant.

Strive, Inc. engages in the provision of an asset management Bitcoin treasury. It is focused on maximizing value for shareholders, accumulating bitcoin and outperforming bitcoin over the long run. The company was founded by Arshia Sarkhani, Jackson Fairbanks, Arman Sarkhani, and Kyle Fairbanks on March 9, 2022 and is headquartered in Dallas, TX.

Strive Inc. - Ordinary Shares - Class A

Strive Inc.

Bitcoin's rebound toward $85K is lifting bitcoin-treasury stocks, with Strive pushing through the heavily watched $30 level as traders speculate elevated short interest could fuel a squeeze on top of the company's ongoing bitcoin purchases funded through preferred-share sales. Skeptics counter that warrant-related dilution and a stretched valuation relative to its holdings leave the rally vulnerable.

Maase, Inc. operates as a integrated provider and operator of artificial intelligence (AI) centric full-scene digital systems. The firm focus on areas of flexible energy deployment and intelligent commercial network operation, and provide closed-loop solutions from computing infrastructure, smart hardware and full-scene services, aiming to achieve large-scale implementation of AI technologies across industries. The company was founded by Hai Feng Yu on August 6, 2018 and is headquartered in Qingdao, China.

Maase Inc. - Ordinary Shares - Class A

Highest Performances Holdings Inc. - ADR

A rapid series of AI computing and API contract announcementsincluding a 12-month 450P FP16 compute agreement with VirtAI Techis driving heavy volume and renewed momentum in the small-cap China AI infrastructure name. Traders are split between reading the contract cadence as proof of enterprise AI monetization and waiting for evidence of margins and cash conversion, with Fed rate-hike volatility adding pressure to the broader small-cap AI trade.

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$SLS Three SLS009 abstracts accepted for presentation at AACR’s Pancreatic Cancer Conference.

That deserves attention.

You don’t generate three separate presentations around the same molecule unless the preclinical work is producing compelling scientific signals.

And these aren’t three versions of the same experiment. SLS009 is being evaluated across KRAS-mutant pancreatic cancer models involving:

• MYC-associated vulnerabilities
• BET + CDK9 synthetic lethality
• CDK9 + KRAS G12D inhibition

This is increasingly looking like much more than an AML asset.

If the SLS009 data weren’t compelling, would it really be featured THREE times at the same AACR conference?

The potential value of SLS009 continues to expand well beyond AML.

https://ir.sellaslifesciences.com/news/News-Details/2026/SELLAS-Life-Sciences-to-Present-Preclinical-Data-on-SLS009-in-Pancreatic-Ductal-Adenocarcinoma-at-the-2026-AACR-Conference-on-Pancreatic-Cancer/default.aspx

$XBI $IBB

Three posters to highlight preclinical activity of SLS009 (tambiciclib) across patient-derived KRAS mutant organoid models of pancreatic cancer - - Studies conducted in collaboration with the University of Wisconsin School of Medicine and Public Health - NEW YORK, Sept. 02, 2026 (GLOBE NEWSWIRE) - SELLAS Life Sciences Group, Inc.