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Cardano is a blockchain platform built on academic research that enables smart contracts and decentralized applications while using significantly less energy than traditional cryptocurrencies like Bitcoin.   What sets Cardano apart is its methodical, research-driven approach — every major feature is peer-reviewed by scientists and cryptographers before being added to the network. This careful process aims to create a more secure and stable foundation compared to platforms that prioritize speed over thorough testing. The platform's native cryptocurrency, ADA, is used to send money, pay transaction fees, and participate in network governance.  Cardano uses a proof-of-stake system to process transactions, which works differently from Bitcoin's mining approach. Instead of competing to solve complex puzzles, users can "stake" their ADA — essentially locking it up temporarily — to become validators who verify transactions. The system selects validators based on how much ADA they've staked and for how long, then rewards them with additional ADA for their participation. This approach uses far less energy than traditional mining while keeping the network secure. The platform also features a two-layer design that separates basic payment transactions from smart contract operations, allowing each function to be optimized independently for better performance.   ADA holders can earn staking rewards by locking up their tokens to help secure the network, vote on proposed changes to the platform, and use ADA for international money transfers with lower fees than traditional services.  Cardano was founded in 2017 by Charles Hoskinson, who previously helped create Ethereum. Hoskinson leads Input Output Global (IOG), the technology company that builds and maintains Cardano's core software. The ecosystem operates through three organizations: IOG handles technical development, the Cardano Foundation promotes adoption and standardization, and Emurgo helps businesses integrate blockchain technology into their operations. This structure distributes responsibilities across multiple groups rather than concentrating control in a single entity.   In February 2025, major asset manager Grayscale Investments filed to create an exchange-traded fund (ETF) for Cardano with the U.S. Securities and Exchange Commission, which would allow traditional investors to buy ADA through their regular brokerage accounts without needing to set up cryptocurrency wallets.Retry

Cardano

Cardano (ADA) is experiencing highly polarized discussion, with recent news around founder Charles Hoskinson's social media activity fueling conversation and some interpreting it as a positive catalyst. Amidst broader crypto market uncertainty and geopolitical concerns, many in the community fear continued declines and label ADA a "scam" or "rugpull." Conversely, a vocal segment is actively buying dips, anticipating a monumental rebound and the potential for an "altcoin season" for the ecosystem.

SSgA Active Trust - SPDR S&P 500 ETF Trust

SPDR S&P 500 ETF Trust is a top discussion point as futures show significant movement, driven by heightened geopolitical tensions surrounding potential new tariffs on European countries related to Greenland. The investor community is sharply divided between expectations of a considerable market pullback and those anticipating a swift 'buy the dip' recovery. This macro-level uncertainty is also prompting notable flows into traditional safe-haven assets.

Ripple is the catchall name for the cryptocurrency platform, the transactional protocol for which is actually XRP, in the same fashion as Ethereum is the name for the platform that facilitates trades in Ether. Like other cryptocurrencies, Ripple is built atop the idea of a distributed ledger network which requires various parties to participate in validating transactions, rather than any singular centralized authority. That facilitates transactions all over the world, and transfer fees are far cheaper than the likes of bitcoin. Unlike other cryptocurrencies, XRP transfers are effectively immediate, requiring no typical confirmation time.  Ripple was originally founded by a single company, Ripple Labs, and continues to be backed by it, rather than the larger network of developers that continue bitcoin’s development. It also doesn’t have a fluctuating amount of its currency in existence. Where bitcoin has a continually growing pool with an eventual maximum, and Ethereum theoretically has no limit, Ripple was created with all of its 100 billion XRP tokens right out of the gate. That number is maintained with no mining and most of the tokens are owned and held by Ripple Labs itself — around 60 billion at the latest count.  Even at the recently reduced value of around half a dollar per XRP, that means Ripple Labs is currently sitting on around $20 billion worth of the cryptocurrency (note: Ripple’s price crashed hard recently, and may be worth far less than $60 billion by time you read this). It holds 55 billion XRP in an escrow account, which allows it to sell up to a billion per month if it so chooses in order to fund new projects and acquisitions. Selling such an amount would likely have a drastic effect on the cryptocurrency’s value, and isn’t something Ripple Labs plans to do anytime soon.  In actuality, Ripple Labs is looking to leverage the technology behind XRP to allow for faster banking transactions around the world. While Bitcoin and other cryptocurrencies are built on the idea of separating financial transactions from the financial organizations of traditional currencies, Ripple is almost the opposite in every sense.  XRP by Ripple price can be found on this page alongside the market capitalization and additional stats.

Ripple

XRP is currently experiencing heightened community discussion, driven by ongoing market volatility and perceived institutional "liquidation hunts," with many holders actively accumulating during dips. Talk of a looming "Clarity Act" and broader geopolitical events like tariffs are fueling varied speculation, as long-term investors highlight its core utility while others voice frustration over its subdued price action relative to wider crypto trends.

ASML Holding NV engages in the development, production, marketing, sales, upgrading and servicing of advanced semiconductor equipment systems. It includes lithography, metrology and inspection systems. The company was founded on April 1, 1984 and is headquartered in Veldhoven, the Netherlands.

ASML Holding NV - New York Shares

ASML Holding NV

ASML is trending strongly following robust earnings from its key customer TSMC, reinforcing optimism around surging AI-driven chip demand. The community is actively discussing ASML's critical "monopoly" in advanced lithography technology, positioning it as an indispensable beneficiary of the ongoing AI infrastructure buildout.

What is the project about? Vara Network is a substrate-based future proof smart contract platform that is fast, scalable, and makes it simple to create and deploy next-generation Web3.0 dApps Vara is the first standalone network in the Gear Protocol  Gear is a next-gen cloud infrastructure platform providing most intuitive and frictionless environment for web2 and web3 developers to build complex infrastructure solutions and disruptive dApps for any ecosystem  What makes your project unique? Vara is built upon three core concepts: The actor model, and persistent memory — two widely adopted primitives from massive computation and microservices architecture spaces  Wasm — a WebAssembly-based virtual machine that runs on all modern browsers. Proven to be faster than any alternative web2 virtual machines  Vara was created to serve as a wasm-native hub for innovative protocols that leverage parallel execution and asynchronous programming to deliver leading decentralized products in any segment  History of your project. Gear Protocol and the Vara Network were originally created by Nikolay Volf, one of the core developers of Polkadot. In 2021, he embarked on building an advanced layer 1 smart contract platform using Substrate, Polkadot's custom framework. His vision included creating a platform that enables fast and efficient execution of robust, feature-rich dApps while in a seamless development environment similar to that of Web 2.0 development. He did this by  harnessing the power of innovative technologies like Wasm, the Actor Model, and Persistent Memory. These technologies significantly enhance smart contract development and provide a seamless end-user experience and provide the foundation for the development of Vara Network.  1. Q2 2021 - Pre-Seed Round: In the second quarter of 2021, the Protocol secured its initial funding through a pre-seed round. This likely involved seeking investment from early-stage investors or venture capitalists to kickstart the development of the project.  2. Q4 2021 - Seed Round: In December 2021 raised $12 Million in Venture Round. Private investment round led by Blockchange Venture. In addition to Blockchange, other top venture capital funds participated in this round, including Three  Arrows Capital, Lemniscap, Distributed Global, LAO, Mechanism Capital, Bitscale, Spartan Group LLC, HashKey, DI Ventures, Elysium Venture Capital, Signum Capital and P2P Economy lead by Konstantin Lomashuk, along with a number of top executives of Web3 Foundation and Parity Technologies. Dr. Gavin Wood, Founder and ex-CEO of Parity Technologies and one of the key individual investors participating in this round.  3. 2022 - Intensive Scaling and Development, First Test Integrations: Throughout the year 2022, Vara was focused on two primary activities. First, the engagement in an extensive outreach process to build up the team. Second, the project advanced its technical development efforts and started working on integrating their technology with various test environments to ensure its functionality and viability.  4. Q4 2022 - Testnet Launch.   5. Q1 2023 - PoA Launch: In the first quarter of 2023, Vara achieved launch of its Proof of Authority (PoA) consensus network, which is a chain candidate for mainnet.  Current Status of Vara:  Presently, the project boasts a talented and diverse decentralized workforce, consisting of dozens of engineers and other community members  to drive the project's success.  One of the remarkable aspects of Vara is its substantial pipeline of initiatives with over 40 projects.  What’s next for your project? Current projects being researched and developed by the community:  - Intensive testing and improvement of the actor model features in the blockchain space  - Launch of the key stack of dApps in our parallel and asynchronous environment   - Development of innovative infrastructure solutions (e.g offchain zk actors including machine learning) independently and together with the segment leaders  What can your token be used for? VARA tokens maintain core utility features required for the network to operate: transaction fees staking and network security governance other: gas pools for gas reservation  Contributors to the Gear protocol are exploring the mechanics of how to distribute a portion of block rewards directly toward dApp developers

Vara Network

Vara Network (VARA CRYPTO) is actively trending with heightened community interest, fueled by recent listings on new exchanges like MEXC and BitMart, and a noticeable surge in trading volume. Community discussions are vibrant, highlighting its utility as a Layer 1 network with an AI-integrated exchange and cross-chain bridging technology, leading many to anticipate substantial 'altseason' gains while citing its perceived undervaluation. Investors are also closely watching the easing of token unlock schedules, which could reduce selling pressure and support long-term growth.

The Compound Governance Token is a governance token on the Compound Finance lending protocol, COMP allows the owner to delegate voting rights to the address of their choice; the owner’s wallet, another user, an application, or a DeFi expert. Anybody can participate in Compound governance by receiving delegation, without needing to own COMP.  Anybody with 1% of COMP delegated to their address can propose a governance action; these are simple or complex sets of actions, such as adding support for a new asset, changing an asset’s collateral factor, changing a market’s interest rate model, or changing any other parameter or variable of the protocol that the current administrator can modify.

Compound

Compound is at the center of a polarized community discussion, with bulls anticipating a significant "supply shock" and potential price surge as the token nears its maximum circulating supply, buoyed by broader altcoin market tailwinds. However, a strong bearish sentiment highlights ongoing governance concerns, a critical report on the Compound Foundation's performance, and consistent underperformance compared to competitors like AAVE. The debate reflects widespread frustration over the token's struggle to maintain gains and perceived market manipulation.

Anavex Life Sciences Corp. is a clinical stage biopharmaceutical company, which engages in the development of different therapeutics for the treatment of neurodegenerative and neurodevelopmental diseases. Its lead compound, ANAVEX2-73, is being developed to treat Alzheimer's and Parkinson's disease and central nervous system diseases, including Rett syndrome. The company was founded by Harvey Lalach and Athanasios Skarpelos on January 23, 2004 and is headquartered in New York, NY.

Anavex Life Sciences Corporation

Anavex Life Sciences Corp

Anavex Life Sciences is gaining traction from its re-examination request to the European Medicines Agency for blarcamesine and its inclusion in the European Commission's ACCESS-AD initiative, which aims to evaluate the drug for Alzheimer's disease. This is further buoyed by positive discussions with the FDA, where the agency requested the full dataset for its Alzheimer's program and recently issued favorable guidance for adaptive trial designs. The community is actively debating blarcamesine's potential as an oral, ARIA-free treatment for Alzheimer's, anticipating significant regulatory and partnership developments following these validations and the upcoming J.P. Morgan Healthcare Conference.

ImmunityBio, Inc. is a clinical stage immunotherapy company. It develops next generation therapies that drive immunogenic mechanisms for defeating cancers and infectious diseases. The company's immunotherapy platform activates both the innate and adaptive immune systems to create long term immunological memory. ImmunityBio was founded by Patrick Soon-Shiong in 2014 and is headquartered in San Diego, CA.

ImmunityBio Inc

ImmunityBio (IBRX) is actively trending following its Anktiva treatment receiving accelerated approval for bladder and lung cancer in Saudi Arabia, which the community sees as a pivotal global validation and a significant catalyst. This news, combined with strong preliminary revenue figures and intensifying discussions about a potential short squeeze, is fueling high expectations for the company's role in revolutionizing cancer care and challenging traditional treatments. The company's scientific progress and global reach are key talking points, with many investors anticipating further regulatory and commercial advancements.

Trump Media & Technology Group Corp. engages in operating social media and in the technology business. Its brands include TRUTH Social, TMTG+ and TMTG News. The company was founded on March 28, 2024 and is headquartered in Sarasota, FL.

Trump Media & Technology Group Corp.

Trump Media & Technology Group is trending amidst intense community debate following discussions around potential tariffs on European nations, stemming from calls for the United States to acquire Greenland for Arctic dominance. Supporters praise this as a bold move for national security and economic leverage, while critics denounce it as a reckless, authoritarian approach risking international alliances and economic stability. The conversation is also colored by broader concerns about the former President's leadership style and its implications for both foreign policy and domestic actions.

Riot Platforms, Inc. is a bitcoin mining company, which engages in the provision of special cryptocurrency mining computers. It invests in Verady, Coinsquare, and Tess. It operates through the Bitcoin Mining and Engineering segments. The Bitcoin Mining segment focuses on maximizing ability to successfully mine Bitcoin by growing hash rate. The Engineering segment designs and manufactures power distribution equipment and custom engineered electrical products that provides them the ability to vertically integrate many of the critical electrical components and engineering service. The company was founded on July 24, 2000 and is headquartered in Castle Rock, CO.

Riot Platforms Inc

Riot Platforms is trending after securing a pivotal 10-year data center lease with AMD, deploying initial critical IT load capacity at its Rockdale facility. This strategic move, funded by a Bitcoin sale, is widely viewed by the community as validating Riot's significant power assets and establishing its credibility in the high-demand AI/HPC infrastructure market. Investors are keenly discussing the potential for further growth from this "blue chip" partnership and the broader implications of chipmakers seeking direct data center infrastructure.

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$CMRX Is this board closed? ONC201 Dordaviprone granted accelerated approval for diffuse midline glioma. $JAZZ stole Chimerix for peanuts, $8.55 per share/$935M was and still is a joke. I never cared for the Mike who spent his days riding around the Indiana countryside because of what I perceived as an inflated ego, and sadly it seems the other Mike (who I did like) was influenced to sell way to cheap. It is too late now but at least there is a life saving treatment for children who have few options. Just my opinion. congrats to the dedicated Chimerix employees for getting this across the finish line. https://www.fda.gov/drugs/resources-information-approved-drugs/fda-grants-accelerated-approval-dordaviprone-diffuse-midline-glioma

sakana

Kelly Mone

On August 6, 2025, the Food and Drug Administration granted accelerated approval to dordaviprone (Modeyso, Jazz Pharmaceuticals, Inc.), a protease activator, for adult and pediatric patients 1 year of age and older with diffuse midline glioma harboring an H3 K27M mutation.

U.S. Food and Drug Administration

FDA grants accelerated approval to dordaviprone

StockTwits Web

Chimerix Inc

Jazz Pharmaceuticals plc

 Is this board closed? ONC201 Dordaviprone granted accelerated approval for diffuse midline glioma. 

 stole Chimerix for peanuts, $8.55 per share/$935M was and still is a joke. I never cared for the Mike who spent his days riding around the Indiana countryside because of what I perceived as an inflated ego, and sadly it seems the other Mike (who I did like) was influenced to sell way to cheap. It is too late now but at least there is a life saving treatment for children who have few options. Just my opinion. congrats to the dedicated Chimerix employees for getting this across the finish line. 