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Applied Digital Corp. is a technology company, which engages in the provision of development and operation of data centers which provide computing power. It operates through the Data Center Hosting Business and HPC Hosting Business segments. The Data Center Hosting Business segment provides energized infrastructure services to crypto mining customers. The HPC Hosting Business segment focuses on the designing, constructing, and operating data centers tailored to support high power density applications like HPC and AI. The company was founded by Wesley Carl Cummins and Jason Zhang in May 2001 and is headquartered in Dallas, TX.

Applied Digital Corporation

APLD is trending amid concerns about the cost of capital related to a large senior secured notes offering, with community members debating its potential impact and investor appetite. Some traders speculate about an upcoming short squeeze due to the high short interest, while others discuss institutional hedging strategies involving long positions and put options. Despite recent price declines, long-term bulls cite significant AI infrastructure contracts and partnerships, urging patience and viewing the dip as a buying opportunity.

Webull Corp. engages in the provision of financial services. It offers trading, wealth management product distribution, market data and information, user community, and investor education. The company was founded by An Quan Wang in 2016 and is headquartered in St. Petersburg, FL.

Webull Corp. - Ordinary Shares - Class A

Webull Corp

Webull ($BULL) is trending as the stock hits all-time lows, triggering strong reactions from both bulls and bears. The community is actively debating whether the stock is a buying opportunity or a value trap, with some citing upcoming earnings as a potential catalyst. Discussions also include the impact of a recent partnership and broader market conditions on the stock's performance.

TMC the metals co., Inc. is a deep-sea minerals exploration company focused on the collection and processing of polymetallic nodules found on the seafloor in international waters of the Clarion Clipperton Zone in the Pacific Ocean (CCZ). These nodules contain high grades of four metals (nickel, copper, cobalt, manganese) which can be used as (i) feedstock for battery cathode precursors (nickel, cobalt and manganese sulfates, or intermediate nickel-copper-cobalt matte) for electric vehicles (EV) and renewable energy storage markets, (ii) copper cathode for EV wiring, energy transmission and other applications and (iii) manganese silicate for manganese alloy production required for steel production. The company was founded in 2021 and is headquartered in Vancouver, Canada.

TMC the metals company Inc

TMC is trending as investors discuss the potential for government funding and the significance of Gerard Barron's trip to DC, alongside commentary on permit timelines. The stock's confidence-inspiring earnings call and the vessel's upcoming work in Japan are also key talking points, though some express concerns about market manipulation and the government shutdown's impact.

Anavex Life Sciences Corp. is a clinical stage biopharmaceutical company, which engages in the development of different therapeutics for the treatment of neurodegenerative and neurodevelopmental diseases. Its lead compound, ANAVEX2-73, is being developed to treat Alzheimer's and Parkinson's disease and central nervous system diseases, including Rett syndrome. The company was founded by Harvey Lalach and Athanasios Skarpelos on January 23, 2004 and is headquartered in New York, NY.

Anavex Life Sciences Corporation

Anavex Life Sciences Corp

AVXL is trending as investors await a decision from the European Medicines Agency (EMA) regarding its Alzheimer's drug, Blarcamesine; the community is split, with some anticipating approval based on the drug's potential and safety profile, while others express concern over trial data and the influence of negative opinions from figures like Martin Shkreli. Discussions also include short squeeze potential, stock manipulation accusations, and comparisons to other Alzheimer's drugs.

Red Cat Holdings, Inc. provides products, services and solutions to the drone industry. It also engages in the provision of distributed data storage, analytics and services for the drone industry.The firm product include Dronebox, which is a blockchain technology that records, stores and analyzes flight data and information from a drone. It operates through the Enterprise Segment. The Enterprise Segment will focus on developing a hardware enabled software platform of services and solutions to government and commercial enterprises and the military. The company was founded by Jeffrey M. Thompson in February 1984 and is headquartered in San Juan, Puerto Rico.

Red Cat Holdings Inc

RCAT is trending due to concerns about reduced guidance for 2025 and disappointing earnings, leading to discussions about management credibility and the impact of government shutdowns on contracts. The community is comparing RCAT's performance to competitors like ONDS, with some expressing frustration over missed promises and potential buying opportunities at lower prices. Sentiment is mixed, with long-term bulls remaining hopeful despite recent struggles.

TSS, Inc. engages in the provision of comprehensive services for the planning, design, development and maintenance of mission-critical facilities and information infrastructure as well as integration services. It operates through the Facilities and Systems Integration Services business segments. The Facilities segment consists of the design, project management, and maintenance of data center and mission-critical business operations. The Systems Integration segment integrates information technology equipment for original equipment manufacturer vendors and customers to be used inside data center environments, including modular data centers. The company was founded by Gerard J. Gallagher on December 20, 2004 and is headquartered in Round Rock, TX.

TSS Inc

TSSI is trending due to recent earnings results that spurred a significant sell-off, with the community debating the company's future prospects and management's communication. Discussions revolve around the impact of facility upgrades, government shutdowns, and the strength of the Dell partnership on TSSI's performance. Some investors see this as a buying opportunity, while others express concerns about the company's execution and transparency.

Applied Materials, Inc. provides manufacturing equipment, services and software to the semiconductor, display and related industries. It operates through the following segments: Semiconductor Systems, Applied Global Services, and Display. The Semiconductor Systems segment includes semiconductor capital equipment for etch, rapid thermal processing, deposition, chemical mechanical planarization, metrology and inspection, wafer packaging, and ion implantation. The Applied Global Services segment provides solutions to optimize equipment, performance, and productivity. The Display segment offers products for manufacturing liquid crystal displays, organic light-emitting diodes, equipment upgrades, and other display technologies for TVs, monitors, laptops, personal computers, smart phones, and other consumer-oriented devices. The company was founded on November 10, 1967 and is headquartered in Santa Clara, CA.

Applied Materials Inc.

Applied Materials is trending downwards following its earnings report, with concerns arising from weaker-than-expected guidance and a significant revenue impact due to new export restrictions, particularly affecting business in China. Community discussion revolves around the severity of the issues and whether the dip represents a buying opportunity or a sign of deeper challenges for the company and the semiconductor equipment sector. Some analysts highlight long-term growth potential, while others point to near-term headwinds and market share losses.

Dog (Bitcoin) is a fully decentralized memecoin on the Bitcoin blockchain, backed by a community dedicated to onboarding millions of people to Bitcoin.  Dog is secured by the Bitcoin blockchain and exists on Bitcoin L1, marking a significant innovation compared to Bitcoin with just BTC. Dog is a Bitcoin Runes token with a minimal on-chain footprint, native to Bitcoin, and stored in UTXOs, just like Bitcoin.   What is the project about?  Dog does not do any paid promotion and is fully decentralized just like Bitcoin. Every influencer who chooses to post about Dog either received the airdrop or bought on secondary. Dog leverages the CC0 license to ensure that Dog is not owned by any single entity but rather by everyone. This had lead to the "DOG Army" independently creating art, apps, lotteries, plushies, websites, podcast, magazines, X account, IRL meetups, clothing lines, PFP collections, Telegram groups, and TikTok/Instagram about Dog.  What makes your project unique?  Dog was airdropped in the fairest memecoin launch ever. In early 2024, the Bitcoin Ordinals ecosystem came together in a full volunteer initiative that rewarded early adopters of the Ordinals Protocol. There was no team allocation, and 100% of the supply was airdropped for free. The airdrop algorithm favored neither whales nor influencers; it was determined by the community and made open-source for maximum transparency.

Dog (Bitcoin)

$DOG is trending as a Bitcoin-native memecoin with a focus on community and a fair launch, contrasting it with other memecoins. Talk centers on potential exchange listings, its connection to Bitcoin's fundamentals, and the strength of its community, the #dogarmy.

Omeros Corp. operates as a biopharmaceutical company. The firm engages in the discovery, development, and commercializing of both small-molecule and protein therapeutics for large market. It also offers orphan indications targeting inflammation, coagulopathies, and disorders of the central nervous system. The company was founded by Gregory A. Demopulos and Pamela Pierce Palmer on June 16, 1994 and is headquartered in Seattle, WA.

Omeros Corporation

Omeros ($OMER) is trending as investors await potential FDA approval for Narsoplimab (NARSO) for TA-TMA by the end of December, with specific focus on the commencement of labeling discussions, a key indicator of progress; some express concern over potential review delays and the impact of the government shutdown. The community is weighing the implications of recent leadership changes at the FDA, with opinions divided over how it might affect OMER's prospects, while also monitoring the progress of the Novo Nordisk deal and potential buy out.

Nu Holdings Ltd. is a holding company, which engages in the provision of digital banking services. The company was founded by David Vélez Osorno, Cristina Helena Zingaretti Junqueira, and Adam Edward Wible on February 26, 2016 and is headquartered in George Town, Cayman Islands.

Nu Holdings Ltd - Ordinary Shares Class A

Nu Holdings Ltd

Nu Holdings ($NU) is trending as investors react to recent earnings and growth metrics, with community members debating whether the subdued market reaction reflects the stock's true potential.  Bullish sentiment centers on the company's impressive customer growth and profitability in Latin America, while bears express concerns about sideways trading and the stock's historical difficulty in breaking resistance levels. Discussions also include potential catalysts, such as expansion into the U.S. market and partnerships with companies like Amazon and OpenAI.

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Will Keytruda Aid MRK's Growth in 2026 After a Subdued Q3?

Merck leans on Keytruda's expanding cancer indications and new SC formulation to sustain growth momentum into 2026 after soft sales in Q3.

Ivonescimab Plus Chemotherapy Demonstrates a Statistically Significant Benefit in Overall Survival with a Hazard Ratio of 0.74 in 2L+ Treatment of Patients with EGFRm NSCLC in HARMONi-A Study Conducted by Akeso in China

Summit Therapeutics Inc. (NASDAQ: SMMT) (Summit, we, or the Company) today noted that our partner, Akeso, Inc. (Akeso, HKEX Code: 9926.HK) published results from the Phase III HARMONi-A trial...

Assetmark Inc. Invests $661,000 in Summit Therapeutics PLC $SMMT

Assetmark Inc. bought a new position in shares of Summit Therapeutics PLC (NASDAQ:SMMT - Free Report) during the 2nd quarter, according to its most recent disclosure with the Securities and Exchange...

Summit Therapeutics to Present at Upcoming Investor Conferences

Summit Therapeutics Inc. (NASDAQ: SMMT) (Summit, we, or the Company) today announced that it will participate in and present at four upcoming investor conferences during the remainder of this year...

Overall Survival Data from HARMONi-A, Featuring Ivonescimab in Combination with Chemotherapy vs. Chemotherapy in 2L+ Treatment of Patients with EGFRm NSCLC in China, to be Showcased at SITC 2025

Summit Therapeutics Inc. (NASDAQ: SMMT) (Summit, we, or the Company) today announced that results from the Phase III HARMONi-A trial, conducted in China and sponsored by our partner, Akeso, Inc...

Buy, Sell or Hold MRK Stock Ahead of Q3 Earnings? Things to Know

MRK faces pressure from weak vaccine sales and rising competition, but strong oncology growth and new launches could support a rebound.

Summit Therapeutics Raises $500 Million in Private Placement

Summit Therapeutics Inc. (NASDAQ: SMMT) (Summit, we, or the Company) today announced that the Company has accepted offers from multiple leading biotech institutional and individual investors to...

SMMT's Q3 Loss Wider Than Expected, Stock Down on Study Amendments

Summit Therapeutics posts a wider Q3 loss as costs surge and investors react to protocol changes in a key ivonescimab study.

Company News for Oct 21, 2025

Companies in The News Are: SMMT, CLF, LHX, COO

Retail buzz around Summit Therapeutics picked up Sunday after the biotech reported what it called a first-of-its-kind result in a major lung cancer study, showing that its experimental antibody ivonescimab, used alongside chemotherapy, outperformed a leading immunotherapy treatment in patients with advanced squamous non-small cell lung cancer (NSCLC).In the late-stage HARMONi-6 trial from Summit’s partner Akeso, the drug combination of ivonescimab plus chemotherapy helped people with the disease live about 11 months before their cancer worsened, compared with about 7 months for those taking the current standard therapy, tislelizumab plus chemotherapy.&nbsp;The results work out to a 40% lower risk of the disease progressing or causing death, a first for this type of lung cancer.Safety Profile Remains ManageableThe PD-1/VEGF bispecific antibody, ivonescimab, also had a manageable safety profile. Serious side effects and discontinuations of treatment were at similar rates to tislelizumab. Most VEGF-related side effects (for example, mild hypertension or proteinuria) were reversible and did not cause patients to stop treatment.Maky Zanganeh, Co-CEO and President of Summit, said the results demonstrate how ivonescimab’s novel mechanism may allow for longer treatment duration and stronger clinical benefit compared with other PD-1 and VEGF therapies given separately. “No more striking is this result than in squamous NSCLC, where the benefit of anti-VEGF therapy has been largely unrealized,” she said.Expanding To Global StudiesSummit is also advancing its HARMONi-3 global Phase III trial, designed to test ivonescimab plus chemotherapy against pembrolizumab (Keytruda) plus chemotherapy in newly diagnosed NSCLC.&nbsp;The company has now split the trial into two parts to evaluate results separately for squamous and non-squamous tumors.The squamous cohort is expected to finish enrollment in the first half of 2026, with data expected later that year, while the non-squamous group should complete enrollment in the second half of 2026.What’s The Buzz On Stocktwits?On Stocktwits, retail sentiment for Summit was ‘extremely bullish’ amid ‘high’ message volume.Some users were cautious, noting concerns about the lack of overall survival data and warning it could weigh on the stock, saying the update is “necessary by [the] FDA for approval.”<stembedurl>https://stocktwits.com/Braindead83/message/632906638</stembedurl>Others struck a more upbeat tone, with one trader expressing excitement for the market open and another calling the press release “very promising.” One user said they expected early volatility, speculating that “smart shorts” could start covering quickly once trading begins.<stembedurl>https://stocktwits.com/AlbertSan/message/632902907</stembedurl><stembedurl>https://stocktwits.com/PatrickandFrankie/message/632882531</stembedurl><a href="https://stocktwits.com/symbol/SMMT">Summit’s stock</a> has risen 18% so far in 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, the Summit Therapeutics company logo is seen on a smartphone screen. (Photo Illustration by Piotr Swat/SOPA Images/LightRocket via Getty Images)

Summit Therapeutics Stock Sparks Retail Buzz After Ivonescimab Combo Cuts Cancer Progression Risk By 40%

The company’s late-stage trial showed patients on ivonescimab plus chemotherapy lived 11 months longer before their cancer worsened compared with those on standard treatment, while maintaining a manageable safety profile. 

Equity

Summit Therapeutics, Inc. is a biopharmaceutical company, that focuses on the discovery, development, and commercialization of patient, physician, caregiver, and societal-friendly medicinal therapies intended to improve quality of life, increase potential duration of life, and resolve serious unmet medical needs. The firm conducts clinical programs focusing on Clostridioides Difficile Infection (CDI). Its lead product, Ridinilazole, is an orally administered small molecule antibiotic that is in Phase III clinical trials for the treatment of CDI. The company was founded in 2003 and is headquartered in Miami, FL.

Summit Therapeutics Inc

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