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GRAIL, Inc. operates as a commercial-stage healthcare company, which engages in the development of a technology for early detection of cancer. It utilizes machine learning, software, and automation to detect and identify multiple deadly cancer types in earlier stages. The company was founded by Jeffrey T. Huber, William H. Rastetter, Mostafa Ronaghi, and Richard D. Klausner on September 11, 2015 and is headquartered in Menlo Park, CA.

GRAIL Inc.

GRAIL (GRAL) is experiencing a sharp decline following mixed trial results for its Galleri cancer test in a UK study that missed a primary endpoint, with bears predicting further collapse. However, many in the community view this as an overreaction, citing strong underlying data for early cancer detection, substantial cash reserves, an ongoing US FDA submission, and recent institutional investments at higher valuations.

Candel Therapeutics, Inc. is a clinical stage biotechnology company, which engages in the development and commercialization of viral immunotherapies. Its pipeline includes CAN-2409 and CAN-3110. The company was founded by Estuardo Aguilar-Cordova in 2002 and is headquartered in Needham, MA.

Candel Therapeutics Inc

Candel Therapeutics is trending after announcing a public stock offering alongside a non-dilutive royalty funding agreement for its prostate cancer therapy, CAN-2409; the community is actively debating whether this represents a strategic capital raise for commercialization and pipeline advancement or a significant dilution impacting shareholder value.

Ardelyx, Inc. is a biopharmaceutical company, which engages in the business of developing and commercializing biopharmaceutical products. The firm is also involved in developing a unique and innovative platform that enables the discovery of new biological mechanisms and pathways to develop potent and efficacious therapies that minimize the side effects and drug-drug interactions frequently encountered with traditional, systemically absorbed medicines. The company was founded by Dominique Charmot, Peter G. Schultz, and Jean M. Frechet in October 2007 and is headquartered in Waltham, MA.

Ardelyx Inc

Ardelyx is trending after its Q4 earnings, which showed strong revenue growth but an EPS miss, as the company prioritizes significant investments in pipeline expansion, including a new patent extending protection to 2042 and dosing the first patient in a Phase 3 CIC trial. Investors are debating the short-term impact of increased expenses versus the long-term value from a potential buyout and rising analyst price targets, despite general market volatility.

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CockCardano

COCK CRYPTO is trending due to its unique real-world asset utility through Cocky Wings LLC, a business generating revenue for token buybacks, within the Cardano ecosystem. The community is actively discussing its growing ecosystem, including staking for passive income in its "Arena" and its connection to the MemesHub.io platform, alongside strong sentiment for continued momentum.

Scilex Holding Co. engages in the acquisition, development, and commercialization of non-opioid pain management products for the treatment of acute and chronic pain. Its products include ZTLido, Elyxyb, and Gloperba. The company was founded on February 21, 2020 and is headquartered in Palo Alto, CA.

Scilex Holding Company

Scilex Holding Company is trending as investors debate the impact of its strategic $20 million investment in Quantum Scan Holdings and continued sales of Datavault AI shares, while community chatter focuses on CEO Henry Ji's controversial leadership, recent dividend revocation, and the company's precarious financial position.

Trulieve Cannabis Corp. engages in the provision of medical cannabis products and services. It cultivates and produces its products in-house and distributes to its branded stores, as well as directly to patients via home delivery. The company was founded by Kim Rivers & Jason Pernell on September 17, 1940 and is headquartered in Quincy, FL.

Trulieve Cannabis Corp - Ordinary Shares (Sub Voting)

Trulieve Cannabis

Trulieve Cannabis is trending amid intense anticipation of a federal executive order to reschedule cannabis to Schedule III, a move widely expected by the community to eliminate the punitive 280E tax burden and unlock significant profitability for U.S. multi-state operators. This potential catalyst, alongside ongoing discussions about its dominant position in Florida and the state's adult-use legalization efforts, is driving strong bullish sentiment despite historical sector volatility.

Codatta

Codatta (XNY CRYPTO) is trending as it demonstrates significant strength and outperformance amidst broader market fluctuations, leading the community to aggressively buy dips and anticipate further upward movement. Discussions highlight its underlying utility in decentralized AI and data.

Cardano is a blockchain platform built on academic research that enables smart contracts and decentralized applications while using significantly less energy than traditional cryptocurrencies like Bitcoin.   What sets Cardano apart is its methodical, research-driven approach — every major feature is peer-reviewed by scientists and cryptographers before being added to the network. This careful process aims to create a more secure and stable foundation compared to platforms that prioritize speed over thorough testing. The platform's native cryptocurrency, ADA, is used to send money, pay transaction fees, and participate in network governance.  Cardano uses a proof-of-stake system to process transactions, which works differently from Bitcoin's mining approach. Instead of competing to solve complex puzzles, users can "stake" their ADA — essentially locking it up temporarily — to become validators who verify transactions. The system selects validators based on how much ADA they've staked and for how long, then rewards them with additional ADA for their participation. This approach uses far less energy than traditional mining while keeping the network secure. The platform also features a two-layer design that separates basic payment transactions from smart contract operations, allowing each function to be optimized independently for better performance.   ADA holders can earn staking rewards by locking up their tokens to help secure the network, vote on proposed changes to the platform, and use ADA for international money transfers with lower fees than traditional services.  Cardano was founded in 2017 by Charles Hoskinson, who previously helped create Ethereum. Hoskinson leads Input Output Global (IOG), the technology company that builds and maintains Cardano's core software. The ecosystem operates through three organizations: IOG handles technical development, the Cardano Foundation promotes adoption and standardization, and Emurgo helps businesses integrate blockchain technology into their operations. This structure distributes responsibilities across multiple groups rather than concentrating control in a single entity.   In February 2025, major asset manager Grayscale Investments filed to create an exchange-traded fund (ETF) for Cardano with the U.S. Securities and Exchange Commission, which would allow traditional investors to buy ADA through their regular brokerage accounts without needing to set up cryptocurrency wallets.Retry

Cardano

Cardano is trending due to significant community debate as it trades near multi-year lows amidst broader crypto market volatility. While many foresee a parabolic recovery, citing recent ecosystem developments like Pyth Network integration and the founder's vision for mainstream blockchain utility, a notable portion of the community expresses skepticism and anticipates further declines.

Walmart, Inc. engages in the retail and wholesale business. The company offers an assortment of merchandise and services at everyday low prices. It operates through the following business segments: Walmart U.S., Walmart International, and Sam's Club. The Walmart U.S. segment operates as a mass merchandiser of consumer products, operating under the Walmart and Walmart Neighborhood Market brands, including walmart.com. The Walmart International segment includes operations of wholly-owned subsidiaries in Canada, Chile, China, and Africa, and majority-owned subsidiaries in India, as well as Mexico and Central America. The Sam's Club segment manages membership-only warehouse clubs and operates samsclub.com. The company was founded by Samuel Moore Walton and James Lawrence Walton on July 2, 1962 and is headquartered in Bentonville, AR.

Walmart Inc

Walmart is a major talking point after its earnings report showcased robust e-commerce and advertising growth alongside a substantial share buyback, even as conservative full-year guidance fuels community debate over its high valuation and the outlook for consumer spending.

StarkNet is a permissionless decentralized Layer 2 (L2) validity rollup, built to allow Ethereum to scale via cryptographic protocols called STARKs, without compromising Ethereum’s core principles of decentralization, transparency, inclusivity and security. The StarkNet Token is needed to operate the ecosystem, maintain and secure it, decide on its values and strategic goals, and direct its evolution. This token will be required for (i) governance, (ii) payment of transaction fees on StarkNet, and (iii) participation in StarkNet’s consensus mechanism.

Starknet

Starknet is trending due to significant technological advancements like its quantum-resistant ZK-STARKs and new enterprise privacy integrations, alongside growing on-chain metrics such as rising TVL and developer activity, which the community sees as a strong opportunity despite past token unlock FUD.

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Nifty 50

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Reliance Industries Ltd.

Zomato Ltd.

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HDFC Bank Ltd.

ITC Ltd.

Adani Enterprises Ltd

Axis Bank Ltd

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