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Greenwich LifeSciences, Inc. engages in the development of a breast cancer immunotherapy designed to prevent the recurrence of breast cancer following surgery. The company was founded by Eric Rothe on August 29, 2006 and is headquartered in Stafford, TX.

Greenwich LifeSciences Inc

Greenwich LifeSciences (GLSI) is trending due to impressive preliminary Phase 3 trial results showing an 80% reduction in breast cancer recurrence, alongside an extended insider lock-up signaling strong management confidence. This news has ignited intense community discussion about its low float, extremely high cost to borrow, and significant short interest, leading to widespread speculation of a substantial short squeeze and a potential multi-billion dollar valuation for its breast cancer therapy.

Litecoin is a peer-to-peer cryptocurrency created by Charlie Lee. It was created based on the Bitcoin protocol but differs in terms of the hashing algorithm used. Litecoin uses the memory intensive Scrypt proof of work mining algorithm. Scrypt allows consumer-grade hardware such as GPU to mine those coins.  Why Litecoin? Litecoin is a cryptocurrency that has evolved from Bitcoin after its own popularity in the industry, this alternative, or ‘altcoin’ has emerged to allow investors to diversify their digital currency package, according to Investopedia. Litecoin is one of the most prominent altcoins and was created by former Google employee and Director of Engineering at Coinbase, Charlie Lee. Litecoin was the first to alter Bitcoin and the most significant difference is that it takes 2.5 minutes for Litecoin to generate a block, or transaction, in comparison to Bitcoin's 10 minutes.  ‘While this matters little to traders, miners who use hardware to run Bitcoin's network cannot switch over to Litecoin. This keeps bigger mining conglomerates away from Litecoin because they cannot easily optimize their profits by swapping to another coin, contributing to a more decentralized experience. Litecoin also has bigger blocks, and more coins in circulation, making it more affordable and swift when transacting,’ Investopedia explained.  As explained above, Litecoin can transact a lot faster than Bitcoin, but there are also a number of other characteristics that investors need to know before trading. Litecoin can handle higher volumes of transactions because of the capability of transacting faster and if Bitcoin attempted to transact on the scale of its altcoin, a code update would be needed. However, Litecoin’s blocks would be larger, but with more ‘orphaned blocks'. The faster block time of litecoin reduces the risk of double spending attacks - this is theoretical in the case of both networks having the same hashing power.  Litecoin Technical Details: The transaction confirmation time taken for Litecoin is about 2.5 minutes on average (as compared to Bitcoin's 10 minutes). The Litecoin network is scheduled to cap at 84 million currency units.   Litecoin has inspired many other popular alternative currencies (eg. Dogecoin) because of its Scrypt hashing algorithm in order to prevent ASIC miners from mining those coins. However it is said that by the end of this year, Scrypt ASIC will enter the mass market.

Litecoin

Litecoin is currently capturing significant attention, driven by enthusiastic discussions around the impending LitVM airdrop and the launch of its Omnichain system, which introduces new yield-earning capabilities. The community is actively debating strong bullish prospects and favorable technical indicators, reinforcing its long-held narrative as "digital silver" within the broader crypto market.

MARA Holdings, Inc. is a digital asset technology company, which engages in mining cryptocurrencies with a focus on the Bitcoin ecosystem. It also deals with owning and operating bitcoin mining facilities or data centers, selling proprietary software or technology to third parties operating in the Bitcoin ecosystem, offering advisory and consulting services to support Bitcoin mining ventures in domestic and international jurisdictions, and generating electricity from renewable energy resources or methane gas capture to power Bitcoin mining projects. The company was founded on February 23, 2010 and is headquartered in Hallandale Beach, FL.

MARA Holdings Inc.

Marathon Digital Holdings Inc

Marathon Digital is trending amidst significant year-end tax-loss harvesting, with the community expressing widespread frustration over its notable underperformance and perceived management issues, particularly regarding share dilution. Despite the stock trading at a discount to its Bitcoin holdings, proponents highlight its strategic pivot into AI/HPC data centers and substantial short interest as potential catalysts for a rebound.

Cardano is a blockchain platform built on academic research that enables smart contracts and decentralized applications while using significantly less energy than traditional cryptocurrencies like Bitcoin.   What sets Cardano apart is its methodical, research-driven approach — every major feature is peer-reviewed by scientists and cryptographers before being added to the network. This careful process aims to create a more secure and stable foundation compared to platforms that prioritize speed over thorough testing. The platform's native cryptocurrency, ADA, is used to send money, pay transaction fees, and participate in network governance.  Cardano uses a proof-of-stake system to process transactions, which works differently from Bitcoin's mining approach. Instead of competing to solve complex puzzles, users can "stake" their ADA — essentially locking it up temporarily — to become validators who verify transactions. The system selects validators based on how much ADA they've staked and for how long, then rewards them with additional ADA for their participation. This approach uses far less energy than traditional mining while keeping the network secure. The platform also features a two-layer design that separates basic payment transactions from smart contract operations, allowing each function to be optimized independently for better performance.   ADA holders can earn staking rewards by locking up their tokens to help secure the network, vote on proposed changes to the platform, and use ADA for international money transfers with lower fees than traditional services.  Cardano was founded in 2017 by Charles Hoskinson, who previously helped create Ethereum. Hoskinson leads Input Output Global (IOG), the technology company that builds and maintains Cardano's core software. The ecosystem operates through three organizations: IOG handles technical development, the Cardano Foundation promotes adoption and standardization, and Emurgo helps businesses integrate blockchain technology into their operations. This structure distributes responsibilities across multiple groups rather than concentrating control in a single entity.   In February 2025, major asset manager Grayscale Investments filed to create an exchange-traded fund (ETF) for Cardano with the U.S. Securities and Exchange Commission, which would allow traditional investors to buy ADA through their regular brokerage accounts without needing to set up cryptocurrency wallets.Retry

Cardano

Cardano ($ADA) is currently a hotbed of intense community FUD, with many investors vehemently labeling it a 'scam' and predicting significant 'rugpulls' and 'dumps,' largely blaming its founder Charles Hoskinson. Despite widespread bearish sentiment suggesting the project is 'dead,' a smaller segment is actively accumulating, anticipating a future market resurgence or positive legislative impact like a 'Clarity Act' run. The pervasive negative sentiment, fueled by perceived price underperformance, is the immediate catalyst driving conversation around $ADA.

TryHard Holdings Ltd. is a lifestyle entertainment company that operates in Japan offering a diverse range of services across the entertainment and hospitality sectors. It operates through the following business segments: Consultancy and management, Event curation, Sub-leasing and Restaurants. The Consultancy and management segment provides expert services to clubs, including operations, event management, and strategic support to enhance performance and engagement. The Event curation segment organize and produce own events, also provides a full suite of services, including event planning, construction, entertainment booking, event operation, and ticket sales. The Sub-Leasing segment acts as an intermediary between landlords and clubs. The Restaurants segment operates several restaurants. The company was founded on October 16, 2013 and is headquartered in Osaka, Japan.

TryHard Holdings Ltd.

TryHard Holdings Ltd. ($THH) is a top trending stock following its recent Initial Public Offering (IPO) on NASDAQ, with community discussion centered on its high volatility as a low-float play. While some investors are optimistic about its significant price appreciation potential, others are highly skeptical, raising concerns about its dramatic price swings and labeling it as a potential "pump and dump."

Ultragenyx Pharmaceutical, Inc. is a biopharmaceutical company, which engages in the identification, acquisition, development, and commercialization of novel products for the treatment of genetic diseases. Its products include Crysvita, Mepsevii, Dojolvi, and Evkeeza. The company was founded by Emil D. Kakkis in April 2010 and is headquartered in Novato, CA.

Ultragenyx Pharmaceutical Inc.

Ultragenyx Pharmaceutical Inc

Ultragenyx Pharmaceutical is trending after its setrusumab drug for osteogenesis imperfecta failed to meet primary endpoints in late-stage trials, prompting a significant stock decline. The community is actively debating whether this represents an overreaction, pointing to the company's existing approved products and deep pipeline as reasons for a potential rebound.

BlackRock Institutional Trust Company N.A. - iShares Silver Trust

iShares Silver Trust

The iShares Silver Trust (SLV) is experiencing intense trading activity amidst a sharp price pullback, largely attributed to increased margin requirements by a major commodities exchange triggering forced liquidations. Investors are fiercely debating whether this represents a "buy the dip" opportunity, fueled by concerns over looming export restrictions from a key global consumer and persistent supply/demand imbalances, or if it signals an unsustainable top after a parabolic ascent. This market action underscores the deep divide between perceived paper market manipulation and the fundamental outlook for physical silver.

#c8ntinuum is rewriting the narrative — prioritizing cooperation over competition among blockchains. Multichain powered protocol unleashing unrivaled mechanisms designed to achieve ultimate interoperability, scalability, and long term sustainability.  c8ntinuum is the first permissionless Layer 0 protocol that supports multiple layers, enabling trust-minimized and secure multi-chain interoperability through zero-knowledge on-chain light clients.

c8ntinuum

CTM is garnering significant attention as community members identify 'Castellum' as a high-risk, high-reward 'sleeper' asset with substantial untapped potential. Discussions highlight strong conviction that it represents a massive opportunity for a long-term swing play.

ImageneBio, Inc. is a clinical-stage biotechnology company that boldly imagines a world where patients can be free from the burden of grievous immunological/autoimmune and inflammatory (I&I) diseases. It focuses on the development of new medicines with differentiated profiles that can effectively control and change the course of I&I diseases for affected patients, treat their symptoms, and improve quality of life. The company was founded in February 2016, and is headquartered in San Diego, CA.

ImageneBio Inc.

ImageneBio, Inc.

ImageneBio ($IMA) is seeing heightened discussion due to conflicting analyst ratings, with Wedbush's $2 target contrasting sharply with Leerink's Outperform rating and $30 target. The stock has experienced recent volatility, attributed by some to competitor news, leading to a community debate over its significant cash value and the potential for its differentiated Atopic Dermatitis treatment, IMG-007, despite a long timeline to key Phase 2b data. Many investors are weighing the substantial institutional backing against concerns about program timelines and recent share price weakness.

What is GoMining? GoMining is a digital mining platform that offers multiple ways to earn Bitcoin and leverage exposure to it via a user-friendly ecosystem powered by the GOMINING utility token. This ecosystem’s key offerings include digital miner collectibles linked to real Bitcoin mining power and a competitive GameFi mining experience in the Miner Wars game. What are Digital Miners? Digital Miners are GoMining’s flagship product, offering an easy and efficient way to mine Bitcoin. Backed by real-world datacenter hashrate and cutting-edge mining hardware, these digital assets work similarly to a call option in finance: users pay the cost to mine Bitcoin (the ‘strike price’) and keep any profits if Bitcoin’s value exceeds this cost. Thanks to access to advanced equipment and wholesale electricity rates—further reducible by up to 20% with the GOMINING token—production costs rival those of large-scale industrial miners. This accessibility and efficiency make GoMining’s Digital Miners a reliable, scalable, and globally available method to leverage long-term Bitcoin potential. What is Miner Wars? Miner Wars is a GameFi, blockchain-based game launched by GoMining in September 2024, offering players an engaging and competitive way to compete for Bitcoin (BTC) and GOMINING payouts. GoMinig mimics how blocks are being solved on the actual blockchain, where ‘Clans’ (groups of players pooling their digital miners’ power) compete to solve blocks. Adding to the strategic depth, players can use Boosts to enhance their scores during each round. ##**What is the GOMINING token?** GOMINING is a utility token that powers the GoMining ecosystem. Directly tied to real mining operations, it also offers a way to leverage Bitcoin. GOMINNG provides up to 20% off digital miner maintenance fees for GoMining users, which boosts token demand as our community grows (currently owning over 1% of global BTC hashrate). With a deflationary model that permanently burns part of maintenance fees paid in GOMINING each week, and over 30% of the supply locked in governance for an average of two years, GOMINING’s scarcity and value are positioned to steadily increase. This makes GOMINING a Bitcoin derivative designed to amplify Bitcoin’s growth within its dynamic ecosystem. GoMining’s suite of innovative Bitcoin leverage products offers a unique way for both experienced crypto users and newcomers to benefit from Bitcoin’s growth, helping to drive its mainstream adoption.

GoMining Token

GoMining Token is trending due to active community engagement centered around "stacking sats," competing for BTC rewards in "Miner Wars," and leveraging passive Bitcoin mining opportunities. Enthusiasts are widely sharing promotional codes and discussing the acquisition of more mining power within the platform's ecosystem.

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Bitcoin has seen massive volatility this quarter as ETFs, macro conditions, and crypto adoption continue to shape price action. As 2025 comes to a close, where do you think Bitcoin ($BTC) will finish on December 31, 2025 (EST)?

Where Will Bitcoin Close on Dec 31, 2025?

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