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Eupraxia Pharmaceuticals Inc. (EPRX) garnered retail attention on Tuesday after the biotech company reported positive data from the Phase 1b/2a portion of its RESOLVE trial evaluating treatment for eosinophilic esophagitis, a digestive system condition. Mid-stage trial data showed up to 76% remission with no serious safety concerns.
EPRX shares were up around 5% at the time of writing.
Results from the EP-104GI study showed strong clinical remission rates: 59% of patients achieved remission at 12 weeks and up to 76% at 24 weeks. Improvements were also seen in swallowing difficulty scores and key disease markers.
A new cohort using improved catheter delivery demonstrated significantly better outcomes, with the treatment well tolerated across all dose levels, with no serious adverse events. Eupraxia’s EP-104GI is backed by its Diffusphere technology, which enables precise drug delivery directly into the target tissues.
This comes after Eupraxia reported positive data from an earlier trial of EP-104GI in January. According to the company, patients receiving the highest dose showed near-complete improvement in tissue health at 12 weeks, while patients with lower doses maintained benefits up to 36 weeks.
Last month, Eupraxia closed a public offering to raise $63.2 million. The company said it would use the gross proceeds to advance EP-104GI, including ongoing and upcoming clinical trials and preparations for a potential commercial launch. A portion of the proceeds will also support research, new clinical programs, and general corporate activities.
Retail sentiment on Stocktwits turned ‘extremely bullish’ from ‘neutral’ a day earlier, amid ‘extremely high’ message volumes.

One user expects “quiet accumulation” before a “breakout attempt.”
Year-to-date, the stock has gained around 1.5%.
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