Nasdaq, S&P 500 Futures Edge Lower Ahead Of Fed Week, AI Earnings Test: Why POET, ATOM, OGN, QCOM, NTLA Are In Focus

Data from Stocktwits shows that retail positioning has cooled on SPY and turned bearish on QQQ.
US stocks illustration.
US stocks illustration. Image via Vecteezy
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Preeti Ayyathurai·Stocktwits
Updated Apr 27, 2026   |   5:05 AM EDT
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  • President Donald Trump scrapped plans to send envoys to Pakistan for Iran talks, while Iran reportedly floated a proposal to reopen the Strait of Hormuz.
  • Five of the ‘Magnificent Seven’ are set to report, with Amazon, Microsoft, Meta Platforms, Alphabet, and Apple all on deck this week.
  • Traders will also be tracking the crucial Fed meeting this week for its rate decision. 

U.S. stock futures were subdued early Monday amid escalating geopolitical tensions in the Middle East, as investors geared up for high-stakes earnings and a Federal Reserve policy decision later this week. 

Over the weekend, President Trump abruptly canceled a diplomatic mission to Pakistan, citing “infighting” in Tehran, while Iran reportedly proposed a new deal to reopen the Strait of Hormuz in exchange for delaying nuclear talks.

As of 4:00 a.m. ET on Monday: Dow, S&P 500, and Russell 2000 futures fell 0.1%, while Nasdaq futures were flat with negative bias. 

Retail sentiment toward the SPDR S&P 500 ETF (SPY), an exchange-traded fund that tracks the S&P 500 Index, has declined to ‘neutral’ from the ‘bullish’ territory, while the Invesco QQQ Trust (QQQ) ETF, which tracks the Nasdaq-100 Index, has slipped to ‘bearish’ from ‘neutral’ last week, as tech gears up for a crucial earnings test with four of the largest AI spenders reporting midweek. 

Trending Stocks To Watch

Organon (OGN) stock rose 15% in early premarket trade. Sun Pharma confirmed an $11.75 billion acquisition of the company, with the deal slated to close in early 2027. 

Poet Technologies (POET): This stock remains on the retail radar after surging over 100% last week on a partnership with Marvell and rumors of a deal with AWS. 

Atomera Inc (ATOM): The stock is surging, clocking a record month following its Synopsys collaboration last week on next-gen semiconductor materials. 

Intellia Therapeutics (NTLA): The stock is in focus today ahead of its release of late-stage clinical data for its hereditary angioedema therapy.

PonyAI (PONY): Has unveiled a next-gen autonomous driving controller powered by Nvidia’s chips.

Oracle (ORCL) finalized a $16 billion financing package for a new data center in Michigan. 

And Qualcomm Inc. (QCOM) shares rose over 6% in early premarket trade on reports that OpenAI is working with the company and MediaTek to develop smartphone processors.

Other tickers trending on Stocktwits at the time of writing included MaxLinear Inc (MXL), United States Antimony Corp (UAMY), and Marathon Digital (MARA).

Other Catalysts To Watch

On the economic front, traders will be watching the release of pending home sales data at 8:30 am ET. 

On earnings radar, watch out for quarterly reports from Verizon (VZ), and Domino’s Pizza (DPZ) before the bell. Meanwhile, Nucor (NUE), and NOV Inc, among others, report after market close today. 

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