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Assertio Holdings, Inc. is a commercial pharmaceutical company, which engages in acquisitions, licensing, and mergers. The firm focuses on portfolio of neurology, inflammation, and pain medications. Its products include INDOCIN, Sympazan, Otrexup, SPRIX, CAMBIA, and Zipsor. The company was founded on August 7, 1995 and is headquartered in Lake Forest, IL.

Assertio Holdings Inc

Assertio Holdings is trending as shareholders voice intense dissatisfaction with the company's $18-per-share sale to Garda Therapeutics, arguing the price significantly undervalues their core growth assets. Investors are actively debating the lack of transparency in the strategic review process, the removal of potential long-term upside in Rolvedon and Sympazan, and the perceived conflict of interest regarding executive compensation.

Global X Funds - Global X Defense Tech ETF

Global X Defense Tech ETF

The Global X Defense Tech ETF is trending as investors capitalize on surging worldwide military spending and a shift toward tech-driven, autonomous warfare. The community is actively discussing its potential for long-term growth driven by geopolitical tensions, with many highlighting its strategic exposure to both domestic defense contractors and international aerospace leaders.

Aave is a decentralized money market protocol where users can lend and borrow cryptocurrency across 20 different assets as collateral. The protocol has a native token called AAVE, which is also a governance token that lets the community decide the direction of the protocol in a collective manner. Lenders can&nbsp;earn interest by providing liquidity to the market, while borrowers can borrow by collateralizing their cryptoassets to take out loans from the liquidity pools.

AAVE

AAVE is trending as investors weigh its long-term potential in the decentralized finance sector, with many discussing its fundamental value, tokenomics, and recent protocol upgrades. While some community members remain focused on long-term accumulation and the potential for a larger breakout, others are debating the impact of ongoing market volatility and the competitive landscape of lending protocols.

XRP is a decentralized digital asset and the native token of the XRP Ledger, a Layer 1 blockchain designed for high-performance global payments. Its primary value proposition is offering a fast, cost-effective alternative to traditional banking systems by enabling near-instant cross-border settlements that finalize in three to five seconds. By serving as a neutral bridge asset between different fiat currencies, it helps financial institutions lower liquidity costs and eliminates the need for pre-funded accounts.  The network is unique because it utilizes a federated consensus protocol instead of energy-intensive mining or staking. This system achieves deterministic finality through a Unique Node List of trusted validators who must reach an eighty percent agreement threshold to permanently record transactions. This infrastructure supports a sustained throughput of 1,500 transactions per second and includes a built-in decentralized exchange that allows for the automated trading of any tokenized asset without intermediaries.  The project traces its origins back to 2004 with Ryan Fugger before being co-founded in its modern form by Jed McCaleb and Chris Larsen. The company, now known as Ripple, works with major financial institutions as partners and investors to build global payment solutions. To protect the network from spam, a small amount of XRP is burned during every transaction, and the token is further utilized by institutions as collateral to access traditional markets and manage digital asset infrastructure.  Institutional adoption of the asset reached a major milestone in November 2025 when the SEC approved the first wave of spot XRP ETFs. These products, offered by major issuers including Bitwise, Grayscale, 21Shares, Canary Capital, and Franklin Templeton, are now listed on prominent exchanges like the NYSE Arca, Nasdaq, and Cboe BZX. While Ripple remains a key contributor to the ecosystem, the underlying XRP Ledger continues to operate as an open-source and decentralized network.

Ripple

XRP is trending as investors digest news regarding its potential role in U.S. payment infrastructure alongside ongoing discussions surrounding regulatory clarity. Community sentiment remains deeply polarized, with bulls positioning for a long-term liquidity-driven breakout while bears voice skepticism over recent price action and institutional adoption timelines.

Ondas, Inc. engages in the development, marketing, and sale of wireless radio systems for secure, wide area mission-critical business-to-business networks. It operates through the Ondas Networks and Ondas Autonomous Systems segments. The Ondas Networks segment provides wireless connectivity solutions enabling mission-critical Industrial Internet applications and services. The Ondas Autonomous Systems segment designs, develops, and markets commercial drone solutions via the Optimus System and Scout System. The company was founded on December 22, 2014 and is headquartered in West Palm Beach, FL.

Ondas Inc.

Ondas Inc

Ondas is trending due to the launch of its ONBERG joint venture in Germany, which focuses on autonomous drone defense systems and has already secured live demonstrations. While the company is expanding its operational footprint across Europe, the stock continues to be a battleground between investors bullish on its defense technology integration and skeptics focused on dilution and ongoing legal challenges.

Amazon.com, Inc. is a multinational technology company, which engages in the provision of online retail shopping services. It operates through the following segments: North America, International, and Amazon Web Services (AWS). The North America segment offers retail sale of consumer products, including from sellers, advertising, and subscriptions services through North America-focused online and physical stores. The International segment focuses on retail sale of consumer products, including sellers, advertising, and subscription services through internationally focused online stores. The AWS segment is composed of global sales of computers, storage, databases, and other services for start-ups, enterprises, government agencies, and academic institutions. The company was founded by Jeffrey P. Bezos in July 1994 and is headquartered in Seattle, WA.

Amazon.com Inc.

Amazon.com Inc

Amazon is surging as the stock breaks toward all-time highs, fueled by an $11.6 billion acquisition of satellite operator Globalstar that investors view as a strategic push to bolster its Project Kuiper network against competition. The community is actively debating whether this move signals a broader transition into a long-term 'harvesting' phase for the company, while many are focused on the stock's impressive momentum and its role as a core infrastructure play in the AI and satellite-connectivity race.

Axon Enterprise, Inc. engages in the development, manufacture, and sale of conducted electrical weapons for personal defense. It operates through the TASER segment and Software and Sensors segment. The TASER segment sells conducted electrical weapons, accessories, and other related products and services. The Software and Sensors segment includes devices, wearables, applications, cloud, and mobile products. The company was founded by Patrick W. Smith and Thomas P. Smith on September 7, 1993 and is headquartered in Scottsdale, AZ.

Axon Enterprise Inc

Axon Enterprise is currently a focal point for investors as it navigates significant volatility driven by a mix of profit-taking, analyst downgrades, and lingering concerns over HQ litigation. Despite the recent price pullback, the community remains actively divided, with bulls highlighting the company's ecosystem moat and AI-driven growth, while bears emphasize valuation concerns and heavy institutional selling.

Lumen Technologies, Inc. is an investment holding company, which engages in the provision of integrated communications to residential and business customers. It operates through the Business and Mass Markets segments. The Business segment provides products and services under four sales channels to enterprise and commercial customers. The Mass Markets segment focuses on consumer and small business customers. The company was founded in 1930 and is headquartered in Monroe, LA.

Lumen Technologies Inc

Lumen Technologies is trending as investors digest the recent confirmation of massive private connectivity fabric contracts and a strategic operational pivot aimed at modernizing its network for AI-driven demand. Community discourse is heavily focused on the stock's significant turnaround potential, with many participants tracking the company's aggressive debt reduction and recent insider buying as key indicators of institutional confidence.

Memecoin on Cronos launched by the Cro Crow community

crow with knife

Crow with knife is capturing significant community attention through its multichain presence and unique deflationary burn mechanism. Supporters are actively driving a cult-like narrative, encouraging others to increase their holdings and framing the project as a standout meme coin with long-term potential.

Nasdaq, Inc. is a holding company, which engages in trading, clearing, exchange technology, regulatory, securities listing, information, and public and private company services. It operates through the following segments: Capital Access Platforms, Financial Technology, and Market Services. The Capital Access Platforms segment delivers liquidity, transparency, and integrity to the corporate issuer and investment community by empowering clients to effectively navigate the capital markets, achieve their sustainability goals, and drive governance excellence. The Financial Technology segment offers platforms that improve the liquidity, transparency, and integrity of the global economy by architecting and operating the markets. The Market Services segment includes equity derivative trading and clearing, cash equity trading, fixed income, currency, and commodities trading. The company was founded by Gordon S. Macklin in 1971 and is headquartered in New York, NY.

Nasdaq Inc - Ordinary Shares - 144A

Nasdaq Inc

Nasdaq is trending as the exchange pushes for SEC approval to expand to 23-hour trading, aiming to modernize market access while investors digest mixed economic data and ongoing geopolitical uncertainties. Community discussion remains heavily focused on potential market volatility, with active debates concerning the long-term impact of AI infrastructure spending and the overall resilience of the current tech-driven rally.

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Cybin Inc. (NASDAQ:HELP) Given Average Recommendation of "Buy" by Brokerages

Shares of Cybin Inc. (NASDAQ:HELP - Get Free Report) have been assigned an average recommendation of "Buy" from the six analysts that are covering the firm, Marketbeat Ratings reports. Five analysts...

Cybin (NASDAQ:HELP) Now Covered by TD Cowen

TD Cowen assumed coverage on shares of Cybin in a research report on Monday. They set a "buy" rating and a $8.00 price objective on the stock...

Cybin (NASDAQ:HELP)  Shares Down 2.1%   - Time to Sell?

Cybin (NASDAQ:HELP) Trading Down 2.1% - Here's What Happened...

CNS Drug Developers Add Pharma Veterans as Sector Nears First FDA Decisions

CNS Drug Developers Add Pharma Veterans as Sector Nears First FDA Decisions CNS Drug Developers Add Pharma Veterans as Sector Nears First FDA Decisions PR Newswire VANCOUVER, BC, March 9, 2026 Issued...

<ul class="summary-bullets"><li>The stock's plunge came after Helus Pharma released results from a mid-stage trial of its anxiety drug HLP004.</li><li>The 36-patient study showed a 10.4-point drop in anxiety scores after six weeks, with 67% of participants responding to treatment.</li><li>Jefferies reiterated a 'Buy' rating and $22 price target, implying a 290% upside from current levels.</li></ul>Shares of Helus Pharma, Inc. (HELP) crashed to their worst trading day on record on Thursday after the company reported results from a mid-stage anxiety drug trial, though Jefferies sees a larger catalyst ahead that could still drive the stock sharply higher.<a href="https://stocktwits.com/symbol/HELP">HELP shares</a> plunged 34% on Thursday to end at $5.64, marking their lowest levels in nearly a year. However, the stock rose over 3% after-hours.&nbsp;<h2 class="st-heading-2">Anxiety Trial Results Trigger Sell-Off</h2>Helus Pharma reported&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/help-stock-tanks-despite-strong-phase-2-results-for-anxiety-treatment-retail-buys-the-dip-ignoring-market-s-pessimism/cZdQHEpRI3O">early results</a> from a mid-stage clinical trial testing HLP004 as a treatment for adults with moderate-to-severe anxiety who continued to have symptoms despite taking antidepressants.The study enrolled 36 patients who received two injections of HLP004 three weeks apart while continuing standard medications. Patients given a 20 mg dose saw anxiety scores drop by about 10.4 points after six weeks. At six months, 67% showed a treatment response and 39% achieved remission.The treatment targets serotonin pathways linked to brain plasticity. In a Phase 1 study using a 30 mg dose, most patients were ready to leave the clinic within about three hours, with the drug’s effects lasting roughly 90 minutes.Generalized anxiety disorder affects more than 20 million adults in the U.S., and roughly half of patients do not respond to first-line treatments, the company said.&nbsp;<h2 class="st-heading-2">Jefferies Bullish On HELP Pipeline</h2>While the anxiety study triggered the sell-off, Jefferies maintained a bullish view on the company’s broader pipeline. The brokerage reiterated a ‘Buy’ rating and a $22 price target on the stock following the data release, implying a 290% upside from current levels.The firm said HLP004 could potentially reduce anxiety symptoms rapidly and durably, and called the generalized anxiety disorder opportunity a $1 billion-plus call option, according to&nbsp;<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.investing.com/news/analyst-ratings/jefferies-reiterates-helus-pharma-stock-rating-on-anxiety-data-93CH-4544705">Investing</a>.&nbsp;However, the brokerage said investors are likely waiting for additional data before gaining greater confidence in the program.&nbsp;Instead, Jefferies highlighted a larger potential catalyst: the Phase 3 Approach trial evaluating Helus Pharma’s lead drug HLP003 for major depressive disorder. HLP003 is an oral drug to treat depression alongside existing medications.&nbsp;Jefferies expects the stock to surge between 100% and 200%, depending on the outcome of the Phase 3 results for HLP003, with results expected in the fourth quarter of 2026.<h2 class="st-heading-2">Depression Trial Pipeline Shows Promise</h2>Last month, results from a mid-stage clinical trial of SPL026 for major depressive disorder were published in the journal Nature Medicine. The randomized study showed a reduction in depressive symptoms within two weeks compared with patients who received a placebo.Researchers also reported that antidepressant effects began appearing as early as one week after treatment, with benefits lasting up to three months in some participants. The findings helped guide the development of Helus Pharma’s newer drug candidates, including HLP004 for anxiety and HLP003 for depression.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>On Stocktwits, retail sentiment for HELP was ‘extremely bullish’ amid ‘extremely high’ message volume.<figure class="image"><img src="https://news.stocktwits-cdn.com/help_ss_png_c6d1ccebbf.webp" alt="help ss.png" width="973" height="141"><figcaption>HELP sentiment and message volume as of March 5 | Source: Stocktwits</figcaption></figure>One user&nbsp;<a href="https://stocktwits.com/macdaddy13333/message/646725489">said</a>, “Correct this is promising info but way too small of a cohort. Big news will be in the phase 3 trials, which can't come out soon enough.”<stembedurl>https://stocktwits.com/macdaddy13333/message/646725489</stembedurl>Another user&nbsp;<a href="https://stocktwits.com/Alex1710/message/646759373">said</a>, “This stock will recover, when they knocked at institutionnel doors for cash they answered come in and have a seat.”<stembedurl>https://stocktwits.com/Alex1710/message/646759373</stembedurl>HELP stock has declined 31% year-to-date.For updates and corrections, email newsroom[at]stocktwits[dot]com.

HELP stock has declined 31% year-to-date. (Photo credit: Getty Images)

HELP Stock Crashes On Anxiety Trial Results, But Here’s Why Jefferies Sees Up To 200% Upside

Jefferies highlighted the Phase 3 Approach trial for depression drug HLP003 as the next key catalyst for the stock.

Equity

<ul class="summary-bullets"><li>U.S. stock futures stabilized late Thursday after a sharp sell-off that erased nearly 800 points from the Dow.</li><li>Eight of the 11 S&amp;P 500 sectors closed lower, with industrials, materials, consumer staples, and healthcare each falling at least 2%.</li><li>Asian stocks mostly fell at Friday's open, pulling the broader MSCI Asia Pacific Index down to its steepest weekly decline since 2020.&nbsp;</li></ul>U.S. stock futures steadied late Thursday following a sharp sell-off that wiped nearly 800 points off the Dow, as geopolitical tensions and surging crude prices kept investors on edge.As of 9.20 p.m. ET, Nasdaq 100 and S&amp;P 500 futures were up 0.1%, while Dow futures were up 0.2%.On Stocktwits, retail sentiment toward the&nbsp;<a href="https://stocktwits.com/symbol/SPY">SPDR S&amp;P 500 ETF Trust (SPY)</a> was ‘neutral’ amid ‘high’ message volume, while sentiment toward the&nbsp;<a href="https://stocktwits.com/symbol/QQQ">Invesco QQQ Trust (QQQ)</a> and&nbsp;<a href="https://stocktwits.com/symbol/DIA">SPDR Dow Jones Industrial Average ETF Trust (DIA)</a> was ‘bearish’ amid ‘high’ message volume.<h2 class="st-heading-2">US Market Drivers</h2>In the prior session, the Dow Jones Industrial Average fell 1.6%. The S&amp;P 500 Index slipped 0.6, while the Nasdaq Composite dipped 0.3%.Eight of the 11 sectors in the S&amp;P 500 closed lower during the session, with industrials, materials, consumer staples, and healthcare each losing at least 2%.Energy markets remained a key driver of volatility. U.S. crude oil prices surged above $80 per barrel during Thursday’s session after Iran reportedly struck an oil tanker with a missile. West Texas Intermediate crude settled up 8.5% at $81.01 per barrel, its highest level since 2024, while Brent crude climbed nearly 5% to around $85.41.The spike in oil prices triggered sharp swings in equity markets. At one point during the session, the Dow fell more than 1,100 points, or about 2.4%, as crude prices crossed the $80 mark before recovering slightly into the close.Oil markets have been shaken by the expanding conflict in the Middle East, which has involved about a dozen countries since hostilities intensified late last month. Traffic through the Strait of Hormuz, a critical route that handles roughly one-fifth of the world’s oil supply, has slowed amid rising security risks.Mohamed El-Erian&nbsp;<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://x.com/elerianm/status/2029646631725887998">said on X</a> that the situation involves key market “guardrails” that are currently under stress and warned that if they fail to hold, “the economic and financial dynamics could shift from the more predictable mean reversion to the more uncertain ‘multiple equilibria.’”Meanwhile, investors are also monitoring policy developments in Washington. Treasury Secretary Scott Bessent said the Trump administration’s newly announced 15% global tariff is expected to take effect this week.Despite the broader decline in equities, Berkshire Hathaway stood out as a rare gainer, rising nearly 3% after the company said it has resumed share repurchases for the first time since 2024. CEO Greg Abel also purchased about $15 million worth of company stock.<h2 class="st-heading-2">Trending Stocks To Watch On NYSE, Nasdaq</h2>Indonesia Energy Corp (INDO), Battalion Oil Corp (BATL), United States Oil Fund (USO): INDO rose over 1% in extended trading, while BATL jumped nearly 16%, as oil prices headed for their&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/indo-batl-uso-in-focus-oil-rally-middle-east-war-1b-fuel-bill/cZdhSDMRIEc">biggest weekly gain</a> since 2022. USO climbed to its highest level in six years.Marvell Technology (MRVL): Shares surged about 15% after-hours as the company issued first-quarter fiscal 2027&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/mrvl-shares-surge-on-solid-q1-2027-guidance/cZdX3fORI3x">revenue guidance</a> above Wall Street estimates and projected full-year revenue growth of more than 30%.Costco Wholesale (COST): Shares slipped slightly in extended trading despite the warehouse retailer reporting&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/costco-q2-sales-growth-trails-wall-street-expectations/cZdX3ouRI3U">second-quarter earnings</a> and revenue that topped analyst estimates.Helus Pharma (HELP): Shares plunged 34% in Thursday’s session, marking their worst trading day on record, after&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/help-stock-tanks-despite-strong-phase-2-results-for-anxiety-treatment-retail-buys-the-dip-ignoring-market-s-pessimism/cZdQHEpRI3O">Phase 2 results</a> for its anxiety treatment HLP004 disappointed investors.Newsmax (NMAX): Shares headed for their&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/newsmax-stock-heads-for-best-week-since-ipo/cZdhkXqRIE2">best weekly performance</a> since the company’s IPO following strong viewership numbers tied to its coverage of President Donald Trump’s State of the Union address.<h2 class="st-heading-2">How Global Markets Are Performing Today</h2>In broader markets, the yield on the benchmark 10-year U.S. Treasury note was around 4.14%, while gold traded near $5,093 an ounce in early Asian trading. Silver was near $82.47, while platinum and palladium also moved higher.Asian markets were lower on Friday, with stocks in Japan, South Korea and Australia falling at the open, pulling the broader MSCI Asia Pacific Index down about 0.6%. The index has dropped roughly 6.7% since the war began, marking its steepest weekly decline since 2020.Among the catalysts for the day are the U.S. employment report, retail sales data, business inventories and consumer credit figures, along with remarks from Federal Reserve officials Mary Daly and Beth Hammack.For updates and corrections, email newsroom[at]stocktwits[dot]com.

The Dow Jones Industrial Average closes above the 50,000 mark for the first time ever, seen in this photo illustration in Brussels, Belgium, on February 7, 2026. (Photo Illustration by Jonathan Raa/NurPhoto via Getty Images)

Dow Futures Hold Ground After 800-Point Selloff As Oil Surge Hits Wall Street: Why MRVL, USO, COST, HELP Are Trending After-Hours

U.S. crude surged above $80 per barrel after a reported Iranian missile strike on an oil tanker.

Helus Pharma Stock Tumbles As Anxiety Drug Study Disappoints

Helus Pharma (Cybin) shares fall after Phase 2 anxiety drug results show symptom improvement, but pressure on the stock.read more...

Anxiety Treatment Boom: GAD Therapies Poised for Multi-Billion Dollar Expansion

Anxiety Treatment Boom: GAD Therapies Poised for Multi-Billion Dollar Expansion Anxiety Treatment Boom: GAD Therapies Poised for Multi-Billion Dollar Expansion PR Newswire NEW YORK, March 5, 2026 GAD...

FY2026 Earnings Forecast for Cybin Issued By HC Wainwright

Cybin Inc. (NASDAQ:HELP - Free Report) - Analysts at HC Wainwright dropped their FY2026 earnings per share estimates for shares of Cybin in a research note issued to investors on Monday, March 2nd...

<ul class="summary-bullets"><li>The clinical trial included 36 participants who continued taking existing medications for generalized anxiety disorder while receiving HLP004 injections.</li><li>Researchers administered two doses three weeks apart and monitored participants for 12 weeks.</li><li>Six months after treatment, about 67% of the combined study group met the criteria for a clinical response.</li></ul>Helus Pharma (HELP) announced encouraging early-stage clinical results for its experimental anxiety treatment HLP004 on Thursday, reporting notable symptom improvement among patients with moderate-to-severe generalized anxiety disorder.&nbsp;The clinical-stage drug developer said its Phase 2 signal detection trial showed statistically meaningful improvements when the therapy was used alongside standard antidepressant treatments.&nbsp;<h2 class="st-heading-2">Trial Demonstrates Significant Anxiety Reduction</h2>In the study, participants receiving a 20-milligram dose of HLP004 alongside standard-of-care treatment experienced an average drop of roughly 10.4 points on the Hamilton Anxiety Rating Scale after six weeks.&nbsp;The clinical trial included 36 participants who continued taking existing medications for generalized anxiety disorder while receiving HLP004 injections. Researchers administered two doses, three weeks apart, and monitored participants for 12 weeks, with additional follow-up planned for up to 1 year.<a href="https://stocktwits.com/symbol/HELP">Helus Pharma stock</a> traded over 22% lower in Thursday’s remarket.&nbsp;<h2 class="st-heading-2">Long-Lasting Response Observed In Many Patients</h2>The company also reported sustained benefits beyond the initial treatment period. Six months after treatment, about 67% of the combined study group met the criteria for a clinical response, while 39% reached remission.Among those receiving the higher 20-milligram dose, 59% showed improvement and 32% achieved remission after six weeks. In the lower-dose group, about 30% of patients met response and remission benchmarks at the same time point.<h2 class="st-heading-2">What Are Stocktwits Users Saying?&nbsp;</h2>Despite the stock’s decline in the premarket session, retail sentiment on Stocktwits around the stock flipped to ‘extremely bullish’ from ‘neutral’ territory the previous day. Message volume shifted to ‘high’ from ‘normal’ levels in 24 hours.&nbsp;<figure class="image"><img src="https://news.stocktwits-cdn.com/Screenshot_2026_03_05_083359_png_25a9744605.webp" alt="HELP’s Sentiment Meter and Message Volume as of 08:30 a.m. ET on Mar. 5, 2026 | Source: Stocktwits" width="925" height="96"><figcaption>HELP’s Sentiment Meter and Message Volume as of 08:30 a.m. ET on Mar. 5, 2026 | Source: Stocktwits</figcaption></figure>A Stocktwits user said they have bought the dip.&nbsp;<stembedurl>https://stocktwits.com/Jimbob3016/message/646658779</stembedurl>HELP stock has gained over 4% year-to-date.Also See:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/liquidia-stock-gains-premarket-on-q4-revenue-beat-investors-are-betting-on-yutrepia-growth/cZdQrwNRI33">Liquidia Stock Gains Premarket On Q4 Revenue Beat – Investors Are Betting On YUTREPIA Growth</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Rising stock market chart on a trading board background.

HELP Stock Tanks 22% Despite Strong Phase 2 Results For Anxiety Treatment: Retail Buys The Dip Ignoring Market’s Pessimism

In the study, participants receiving a 20-milligram dose of HLP004 alongside standard-of-care treatment experienced an average drop of roughly 10.4 points on the Hamilton Anxiety Rating Scale after six weeks. 

Cybin, Inc. operates as a clinical-stage biopharmaceutical company on a mission to create safe and effective psychedelic-based therapeutics to address the large unmet need for new and innovative treatment options for people who suffer from mental health conditions. It is currently developing CYB003, a proprietary deuterated psilocybin analog for the treatment of major depressive disorder and CYB004, a proprietary deuterated DMT molecule for generalized anxiety disorder and has a research pipeline of investigational psychedelic-based compounds. The company was founded by Paul Glavine, Eric So, and John Kanakis on October 13, 2016 and is headquartered in Toronto, Canada.

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