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Shiba Inu (SHIB) is a meme token which began as a fun currency and has now transformed into a decentralized ecosystem. During the initial launch, 50% of the supply was allocated into Vitalik Buterin's ethereum wallet.   As a result of that, Vitalik proceeded to donate 10% of his SHIB holdings to a COVID-19 relief effort in India and the remaining 40% is burnt forever. That donation was worth about $1 billion at that time, which makes it one of the largest donation ever in the world.  What is the Shiba Inu community working on right now? The Shiba Inu team launched a decentralized exchange called Shibaswap with 2 new tokens, LEASH and BONE. LEASH is a scarce supply token that is used to offer incentives on Shibaswap. BONE is the governance token for holders to vote on proposals on Doggy DAO.

Shiba Inu

Shiba Inu is trending amid a strong community debate, with many anticipating a broader "alt season" and "return of the memes" after a period of market decline. While some express strong confidence and are actively accumulating, others view the token with skepticism, citing its past performance and questioning its long-term viability as a meme coin.

Bonk is a dog-themed memecoin on the Solana blockchain, launched on Christmas Day 2022 to revitalize the Solana community following the FTX collapse. Created by an anonymous team of 22 Solana developers and builders, Bonk distributed 50% of its total 100 trillion token supply via airdrop to community members including NFT collectors, developers, and artists.   The project positions itself as "the first Solana dog coin for the people, by the people," explicitly rejecting venture capital backing in favor of grassroots community ownership. What sets Bonk apart from other memecoins is its combination of fair launch mechanics, extensive ecosystem integration, and active deflationary strategy.   Built on Solana, BONK benefits from fast transaction speeds and low fees that make it practical for everyday use. Native products include LetsBonk.fun (a memecoin launchpad that briefly became Solana's market leader in 2025, surpassing Pump.fun with over 78% market share), BonkSwap (a decentralized exchange) and BonkBot (a Telegram trading bot with built-in burn mechanics).   BONK is available across 10 blockchain networks and listed on major exchanges including Binance, Coinbase, Kraken, and Robinhood. Governance is handled by BonkDAO, which holds 15% of the token supply and makes decisions through on-chain voting.   The community has organized several major burn events, most notably the December 2024 BURNmas campaign that destroyed 1.69 trillion tokens worth over $50 million. In September 2025, Nasdaq-listed Safety Shot, Inc. formed BONK Holdings LLC and acquired over 2.5% of the circulating supply (valued at $55-63 million), making BONK one of the first memecoins to attract formal corporate treasury adoption. Core contributor Nom was appointed to Safety Shot's board, and the company holds a 10% revenue share in LetsBonk.fun.  As with all memecoins, BONK is a highly speculative asset with substantial volatility. Its value is primarily driven by community sentiment, social media momentum, and meme culture rather than traditional utility.   The anonymous team, while common in the memecoin space, means investors should exercise appropriate caution. Despite these risks, Bonk has established itself as one of the most successful community-driven tokens in the Solana ecosystem, approaching 1 million unique holders and expanding from a simple memecoin into meaningful DeFi infrastructure.

BONK

BONK is actively trending following the launch of Europe's first ETP and the anticipation of a 1 trillion token burn as the community nears 1 million holders, fueling optimism for a significant price surge. Many in the community are advocating for "diamond hands" conviction, anticipating a major "alt/meme season" and a "10x run" within the Solana ecosystem. Adding to the bullish sentiment, the token has launched a new Perp dex with revenue allocated to the Bonk DAO, alongside discussions of potential benefits from legal challenges faced by competing platforms.

Avalanche is a high throughput smart contract blockchain platform. Validators secure the network through a proof-of-stake consensus protocol. It is said to be fast, low cost, and environmental friendly.

Avalanche

Avalanche (AVAX) is trending amid discussions of significant institutional interest, fueled by its potential for Real World Asset (RWA) tokenization and a new ETF filing that includes staking. Despite some investor frustration over recent price action, the community remains highly engaged, emphasizing AVAX's strong fundamentals, unique subnet architecture, and deflationary tokenomics as key drivers for future growth and adoption. The ongoing debate revolves around the disconnect between these bullish developments and current market performance.

What is the project about? Pepe is a community based meme token surround the iconic meme Pepe the frog. Pepe aims to leverage the power of such an iconic meme to become the most memeable memecoin in existence.   What makes your project unique? Pepe is here to make memecoins great again. Ushering in a new paradigm for memecoins, Pepe represents the memecoin in it's purest simplicity. With zero taxes, liquidity locked forever, and contract immutable, Pepe is for the people, forever. Pepe is about culture, rallying together a community to have fun and enjoy memes, fueled purely by memetic power.   History of your project. Pepe was stealth launched on Friday, April 14th, 2023.   What’s next for your project? Pepe will focus on developing a tight-knit community around the token and building resources to enrich the communities knowledge and success in crypto through a token gated group, newsletter, and more tools.   What can your token be used for? Pepe can be used to speculate on the power of memes, and does not pretend to be anything more.

Pepe

Pepe is currently a hot topic in the crypto community, with many anticipating an upcoming "alt season" reminiscent of past meme coin rallies. Enthusiasts are actively discussing accumulating more PEPE during market pullbacks and holding for substantial growth, fueled by strong collective belief in the coin's potential. The prevailing sentiment indicates expectations for significant upward momentum, as traders look for major breakthroughs.

English version Introducing SWFTCoin (SWFTC) $SWFTC: Powering SWFT Blockchain and AI Services (SWFTGPT)  SwftCoin ($SWFTC) is the native utility token driving SWFT Blockchain's AI-powered ecosystem, SWFTGPT, and the first ever AI token featured on Coinbase. SWFTGPT is also the first domain-specific LLM for crypto.  SwftCoin key features include: 50% Reduced Transaction Fees: Lower costs on all transactions. AI Service Payments: Use $SWFTC to access SWFTGPT. Tools include expert market analysis,  predictions, and intelligent trading solutions.  Membership Benefits: Unlock premium features and AI agent services within SWFTGPT. AI-Powered Swaps: Enable precise, fast cross-chain transactions and analytics. SWFT Blockchain combines AI innovation with blockchain infrastructure, simplifying crypto trading while enhancing functionality through $SWFTC.   Chinese version $SWFTC：驱动 SWFT Blockchain 和 AI 服务（SWFTGPT） SwftCoin ($SWFTC) 是 SWFT Blockchain 的原生实用代币，为其 AI 驱动的生态系统 SWFTGPT 提供支持，同时也是 Coinbase 上首个 AI 代币。SWFTGPT 也是首个专注于加密领域的特定领域大型语言模型 (LLM)。 SwftCoin 的主要功能包括： 1、50% 交易费减免：降低所有交易成本。 2、AI 服务支付：使用 $SWFTC 访问 SWFTGPT 工具，包括专家市场分析、预测以及智能交易解决方案。 3、会员权益：解锁 SWFTGPT 的高级功能和 AI 代理服务。 4、AI 驱动的闪兑：实现精准快速的跨链交易和数据分析。 SWFT Blockchain 将 AI 创新与区块链基础设施结合，通过 $SWFTC 简化加密交易，并提升其功能性。

SwftCoin

SwftCoin (SWFTC) is currently a top trending crypto, fueled by community excitement surrounding potential new major exchange listings, particularly Coinbase, and a notable surge in trading volume. Investors are actively discussing its fully diluted supply, AI-integrated exchange, and crucial cross-chain bridging technology, anticipating substantial "altseason" gains. Many in the community view it as an undervalued asset, accumulating positions for its pivotal role in the evolving multi-chain ecosystem.

Sensei Biotherapeutics, Inc. is a clinical-stage biopharmaceutical company which focuses on the discovery, development, and delivery of next generation immunotherapies for the treatment of cancer and infectious diseases. The company was founded in 1999 and is headquartered in Rockville, MD.

Sensei Biotherapeutics Inc

Sensei Biotherapeutics (SNSE) is trending with a surge in trading volume, as community speculation mounts for a short squeeze driven by its notably low share float. The company's recent strategic review, involving a significant restructuring and exploration of value-maximizing alternatives like a merger or sale, is adding to the intense market conversation. Traders are actively watching this 'nano floater' for a potential parabolic breakout, drawing comparisons to other recent low-float runners.

Ouster, Inc. engages in the provision of high resolution digital lidar sensors that offer advanced 3D vision to machinery, vehicles, robots, and fixed infrastructure assets. The company was founded by Angus Pacala and Mark Frichtl on June 30, 2015 and is headquartered in San Francisco, CA.

Ouster Inc - Ordinary Shares - Class A

Ouster is trending as investors digest its strong Q3 earnings and raised Q4 guidance, prompting multiple analyst upgrades and leading many to view the recent stock pullback as a compelling buying opportunity. The community is actively discussing Ouster's robust financial position and its critical role in enabling the rapidly expanding 'Physical AI' landscape across diverse sectors like robotics, smart infrastructure, and defense. This narrative is further amplified by market anticipation of potential interest rate cuts and the ongoing consolidation within the LiDAR industry.

Memecoin on Injective taken over by the community.

Nonja

NONJA CRYPTO is trending as its community actively positions it as a high-leverage play on the Injective ecosystem, anticipating significant upside with Injective's robust fundamentals and upcoming market catalysts. Enthusiasts highlight NONJA's strong community, high burned liquidity, and successful NFT collections, believing it to be a resilient and undervalued gem poised for substantial growth.

Aerodrome Finance is a next-generation AMM designed to serve as Base's central liquidity hub, combining a powerful liquidity incentive engine, vote-lock governance model, and friendly user experience. Aerodrome inherits the latest features from Velodrome V2.

Aerodrome Finance

Aerodrome Finance (AERO) is a top trending crypto, fueled by its significant revenue generation and strategic role as the leading liquidity hub within the rapidly growing Base ecosystem. The community is buzzing about AERO's strong tokenomics, including buybacks and its anticipated merger with Velodrome, which is set to establish a powerful cross-chain super-DEX. Despite market volatility, many investors are seizing current price levels as a prime opportunity, highlighting AERO's fundamental strengths and future potential.

Choctopus is an SPL Token on the Solana blockchain and has a total supply of 1 billion tokens. It is currently listed on Raydium DEX and 30% of total token supply is vested (locked) in a smart contract until November 25th, 2025. After the initial vesting period is reached, 10% of the vested token supply (30 million tokens), will be released every quarter until the vesting supply pool is depleted on February 25th, 2028. Choctopus was founded by a group of close friends who's goal is to provide eccentric memes and future utilities such as NFT's and Staking rewards for its holders. Other avenues of the tokens growth and utility will be decided on by future votes held by its holders.

Choctopus

The crypto community is buzzing with strong bullish sentiment around CHOCTOPUS CRYPTO, actively discussing its potential for significant gains and urging others to accumulate. Many users are highlighting consistent liquidity additions as a key factor and noting its perceived resilience even as related assets experience dips, fueling widespread optimism.

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Actuate Therapeutics (NASDAQ:ACTU) Trading 2.7% Higher - Here's What Happened

Actuate Therapeutics (NASDAQ:ACTU) Trading 2.7% Higher - Time to Buy...

Actuate Therapeutics, Inc. (ACTU) Upgraded to Buy: What Does It Mean for the Stock?

Actuate Therapeutics, Inc. (ACTU) has been upgraded to a Zacks Rank #2 (Buy), reflecting growing optimism about the company's earnings prospects. This might drive the stock higher in the near term.

Voss Capital LP Purchases 143,759 Shares of Actuate Therapeutics, Inc. $ACTU

Voss Capital LP grew its position in Actuate Therapeutics, Inc. (NASDAQ:ACTU - Free Report) by 101.0% in the 2nd quarter, according to its most recent filing with the SEC. The firm owned 286,140...

How Much Upside is Left in Actuate Therapeutics, Inc. (ACTU)? Wall Street Analysts Think 214.06%

The average of price targets set by Wall Street analysts indicates a potential upside of 214.1% in Actuate Therapeutics, Inc. (ACTU). While the effectiveness of this highly sought-after metric is questionable, the positive trend in earnings estimate revisions might translate into an upside in the stock.

BIOS Capital Management LP Buys 71,428 Shares of Actuate Therapeutics, Inc. $ACTU

BIOS Capital Management LP raised its stake in shares of Actuate Therapeutics, Inc. (NASDAQ:ACTU - Free Report) by 0.7% during the 2nd quarter, according to the company in its most recent Form 13F...

What is HC Wainwright's Estimate for ACTU FY2025 Earnings?

Actuate Therapeutics, Inc. (NASDAQ:ACTU - Free Report) - Analysts at HC Wainwright boosted their FY2025 EPS estimates for shares of Actuate Therapeutics in a research report issued on Wednesday...

HC Wainwright Has Negative Forecast for ACTU FY2029 Earnings

Actuate Therapeutics, Inc. (NASDAQ:ACTU - Free Report) - HC Wainwright reduced their FY2029 EPS estimates for shares of Actuate Therapeutics in a note issued to investors on Wednesday, November 19th...

Actuate Therapeutics (NASDAQ:ACTU) Shares Up 0.5% After Better-Than-Expected Earnings

Actuate Therapeutics (NASDAQ:ACTU) Stock Price Up 0.5% Following Strong Earnings...

Actuate Therapeutics (NASDAQ:ACTU) Announces Quarterly Earnings Results, Beats Estimates By $0.02 EPS

Actuate Therapeutics (NASDAQ:ACTU - Get Free Report) announced its earnings results on Thursday. The company reported ($0.25) earnings per share (EPS) for the quarter, beating analysts' consensus...

Actuate Therapeutics, Inc. (ACTU) announced on Monday that it has amended its application to the U.S. Food and Drug Administration (FDA) for its lead investigational drug Elraglusib in the treatment of pancreatic cancer.The company <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/news-release/2025/09/22/3153932/0/en/Actuate-Therapeutics-Provides-FDA-with-Updated-Clinical-Data-Package-to-Support-Planned-Regulatory-Interactions-with-FDA-and-EMA-Over-the-Coming-Months.html">stated</a> that it has amended the investigational new drug (IND) application with updated clinical data from its ongoing international mid-stage trial of the drug in the first-line treatment of metastatic pancreatic cancer. The study showed a statistically significant improvement in median overall survival with the combination arm of Elraglusib plus Gemcitabine/nab-paclitaxel (GnP) versus GnP alone, in addition to a 37% reduction in the risk of death.The data is intended to support planned regulatory submissions with the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) beginning later this year and continuing into early 2026, the company said. It also added that the data strengthens the case for Elraglusib as a back-bone therapy that can be combined with different regimens used to treat pancreatic cancer.The company is currently studying Elraglusib in pancreatic cancer with three ongoing trials in combination with current standards of care and novel immunotherapies.<a href="https://stocktwits.com/symbol/ACTU">ACTU shares</a> traded 6% higher at the time of writing. On Stocktwits, retail sentiment around ACTU jumped from ‘bearish’ to ‘neutral’ territory over the past 24 hours, while message volume stayed at ‘normal’ levels.<figure class="image"><img style="aspect-ratio:576/63;" src="https://news.stocktwits-cdn.com/Screenshot_2025_09_22_at_11_15_37_AM_png_49248344ea.webp" alt="ACTU's Sentiment Meter and Message Volume as of 11:15 a.m. ET on Sept. 22, 2025 | Source: Stocktwits" width="576" height="63"><figcaption>ACTU's Sentiment Meter and Message Volume as of 11:15 a.m. ET on Sept. 22, 2025 | Source: Stocktwits</figcaption></figure>Actuate also stated that its recent $17.25 million public offering provides an extended runway into the second half of 2026.“We have already updated the clinical data package on file with the FDA, and during the remainder of this year and into the first quarter of 2026, we expect to gain clarity on Elraglusib’s regulatory path forward for the first-line treatment of metastatic PDAC,” said CEO Daniel Schmitt.ACTU stock is down by 11% this year but up by 6% over the past 12 months.&nbsp;Read also:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/tesla-stock-rallies-after-piper-sandler-hikes-price-target/chDQA76R32Z">Tesla Stock Rallies After Piper Sandler Hikes Price Target – More Details Inside</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

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Actuate Therapeutics Stock Rises After Updating FDA Application For Lead Investigational Drug In Treating Pancreatic Cancer

Actuate on Monday also said that its recent $17.25 million public offering provides an extended runway into the second half of 2026. 

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