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Pyth Network is a decentralised oracle network designed to provide real-time financial market data to decentralised applications (dApps) across multiple blockchains. It allows developer to secure smart contracts with reliable, low-latency market data from institutional sources, and build apps with high-fidelity oracle feeds designed for mission-critical systems.

Pyth Network

Pyth Network is trending due to its selection by the U.S. Department of Commerce to distribute economic data on-chain, a move seen as a major step for decentralized infrastructure. The community is actively discussing potential price targets and the broader implications of government adoption of blockchain technology. Some users also believe that this could be the start of a long term hold.

Dog (Bitcoin) is a fully decentralized memecoin on the Bitcoin blockchain, backed by a community dedicated to onboarding millions of people to Bitcoin.  Dog is secured by the Bitcoin blockchain and exists on Bitcoin L1, marking a significant innovation compared to Bitcoin with just BTC. Dog is a Bitcoin Runes token with a minimal on-chain footprint, native to Bitcoin, and stored in UTXOs, just like Bitcoin.   What is the project about?  Dog does not do any paid promotion and is fully decentralized just like Bitcoin. Every influencer who chooses to post about Dog either received the airdrop or bought on secondary. Dog leverages the CC0 license to ensure that Dog is not owned by any single entity but rather by everyone. This had lead to the "DOG Army" independently creating art, apps, lotteries, plushies, websites, podcast, magazines, X account, IRL meetups, clothing lines, PFP collections, Telegram groups, and TikTok/Instagram about Dog.  What makes your project unique?  Dog was airdropped in the fairest memecoin launch ever. In early 2024, the Bitcoin Ordinals ecosystem came together in a full volunteer initiative that rewarded early adopters of the Ordinals Protocol. There was no team allocation, and 100% of the supply was airdropped for free. The airdrop algorithm favored neither whales nor influencers; it was determined by the community and made open-source for maximum transparency.

Dog (Bitcoin)

$DOG.X, a memecoin on the Bitcoin network, is trending as the community rallies around its fair distribution and potential to outperform other meme coins. Some believe it could become the leading meme on Bitcoin, citing its strong community and organic growth. The potential for listings on major exchanges and the backing of a publicly listed company, $CBLO, are also fueling interest.

WorldFinancial

WorldFinancial ($WLFI.X) is trending as the community discusses its potential, governance, and links to prominent figures. Community members are weighing in on potential buybacks, token burns, and the possibility of mass adoption through real-world asset tokenization. Some traders are noting recent price volatility and debating whether it presents a buying opportunity or a sign of a pump and dump scheme.

Wrapped Centrifuge

Wrapped Centrifuge is gaining attention as community members actively discuss its potential breakout and encourage others to take a look. Some users point to news and increasing volume as potential catalysts, while others highlight its low supply. There's also discussion around the difference between $CFG.X and $WCFG.X.

ProShares Trust - ProShares Short Dow30 -1x Shares

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$DOG is trending as the community discusses its potential as the 'DOGE of Bitcoin' and its fair, presale-free distribution. Bullish sentiment surrounds CBLO's increasing treasury holdings of DOG coins, with some anticipating ETF possibilities and tier 1 exchange listings. Conversation highlights $DOG's strong community and its activities within the Bitcoin ecosystem, particularly regarding Runestones and Ordinals.

StickyFam

StickyFam ($FAM.X) is trending as the community rallies around its potential, highlighting its growing follower base and recent listing on BingX. Comparisons to coins within the $DOGE.X and $SOL.X ecosystem are circulating, with many believing that $FAM.X is still early and poised for significant growth due to upcoming catalysts like CEX listings.

Gyrodyne LLC engages in the management of a portfolio of medical office and industrial properties. Its properties include Flowerfield, Port Jefferson Professional Park, Courtland Medical Center, and Grove. The company was founded by Peter James Papadakos in 1946 and is headquartered in St. James, NY.

Gyrodyne LLC

GYRO is trending due to a recently announced land sale, which the company anticipates will significantly boost its net asset value per share. The stock's low float is fueling speculation of a potential parabolic run, with community members comparing it to other recent low-float runners. Discussions also focus on key breakout levels and potential price targets amid the increased attention.

Dynamix Corp. is a blank check company, which engages for the purpose of effecting a merger, amalgamation, share exchange, asset acquisition, share purchase, reorganization or similar business combination with one or more businesses. The company was founded on June 13, 2024 and is headquartered in Houston, TX.

Dynamix Corp - Ordinary Shares - Class A

The ticker change from DYNX to ETHM is driving interest, as the company moves closer to its merger with The Ether Machine. Community members are actively discussing the company's Ethereum holdings relative to its market cap and comparing it to other ETH-related stocks. Some are also speculating on the potential impact of new ETH acquisitions on the share price.

Alcoa Corp. engages in the bauxite mining, alumina refining, and aluminum smelting and casting. It operates through the Alumina and Aluminum segments. The Alumina segment consists of a refining system, including the mining of bauxite, which is then refined into alumina, a compound of aluminum and oxygen that is the raw material used by smelters to produce aluminum metal. The Aluminum segment is composed of smelting and casthouse system. The company was founded by Charles Martin Hall on July 9, 1886 and is headquartered in Pittsburgh, PA.

Alcoa Corp

Alcoa ($AA) is trending as the community discusses its strong earnings report and potential benefits from tariffs, though some caution about potential headwinds. Bullish sentiment is fueled by analyst upgrades and a positive long-term outlook, while others are wary of short-term volatility. Community members are actively trading options, anticipating price movements based on the latest news.

Forward Industries, Inc. engages in the provision of integrated design, development, and manufacturing solutions for top tier medical and technology customers worldwide. It operates through the following segments: OEM Distribution, Retail Distribution, and Design. The OEM Distribution segment sources and distributes carrying cases and other accessories for medical monitoring and diagnostic kits and a variety of other portable electronic and non-electronic devices. The Retail Distribution segment sells smart-enabled furniture and a variety of other products through agreements with various retailers, both in stores and through online retailer websites. The Design segment provides hardware and software product design and engineering services. The company was founded in 1961 and is headquartered in Hauppauge, NY.

Forward Industries, Inc.

Forward Industries ($FORD) is trending as traders mistakenly believe it's Ford Motor Company ($F), leading to unexpected price action. The community is actively discussing the mix-up, with some attempting to capitalize on the confusion while others point out the company's fundamentals and low float. Recent compliance news and comparisons to other low-float runners like $AREB are also fueling interest.

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Apellis Pharmaceuticals is drawing renewed attention from short sellers even as its stock extends a rebound sparked by better-than-expected&nbsp;bottom-line results.Short interest as a percentage of free float rose to 21.1% last week, the highest in three weeks, after bottoming near 21% in late July, according to Ortex data compiled by The Fly.&nbsp;Days-to-cover climbed to 2.8 from 2.6, although volumes stayed heavy following the earnings release, limiting further upside pressure.Shares gained 13.5% in the five sessions through Thursday and have now rallied 45% since July 31, when Apellis reported a second-quarter loss of $0.33 per share, narrower than&nbsp;analysts’ expectations.&nbsp;<a href="https://stocktwits.com/symbol/APLS">Apellis’ stock</a> rose 0.5% on Friday to close at $27.75, its highest level in six months, extending a four-session winning streak.Revenue of $178.5 million missed consensus by about $10 million, but investors cheered the earnings surprise along with regulatory and business updates.&nbsp;Quarterly sales were driven by $151 million from Syfovre, its treatment for geographic atrophy, and $21 million from Empaveli for paroxysmal nocturnal hemoglobinuria. Apellis also secured FDA approval of Empaveli for rare kidney diseases C3G and primary IC-MPGN, the first approved therapies for these conditions.Additionally, Apellis signed a capped royalty deal with Sobi worth up to $300 million for ex-U.S. Aspaveli sales and ended June with $370 million in cash.&nbsp;The company said the combination of cash, the Sobi payment, and future revenues should be sufficient to fund operations to profitability.Following the quarterly results, Goldman Sachs&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/retail-buzz-surges-for-apellis-as-goldman-hikes-price-target-after-solid-syfovre-sales-fda-win-for-kidney-drug/chr3ZbiRdGS">raised its price target</a> to $26 from $24, citing strong quarterly execution and long-term potential across its complement-focused pipeline.&nbsp;Citi lifted its target to $46 from $41, calling Empaveli “best-in-class,” while Scotiabank raised its target to $22 on confidence in launch execution. Baird, BofA, and Morgan Stanley also issued upward revisions earlier in August, reflecting improving sentiment.Despite the rebound, the pickup in short positioning suggests some investors expect profit-taking after the momentum-driven surge.On Stocktwits, retail sentiment for Apellis&nbsp;remained ‘bearish’ amid ‘extremely low’ message volume.Apellis’ stock has declined 13% so far in 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

APLS stock has declined 13% so far in 2025. (Photo credit: Getty Images)

Apellis Short Bets Edge Higher As Stock Jumps 45% Since Late July Q2 Report — Retail Traders Stay Wary

Apellis stock has surged since its earnings, but rising short interest suggests some investors are betting on profit-taking.

Equity

Retail chatter around Apellis Pharmaceuticals spiked Thursday after Goldman Sachs raised its price target to $26 from $24, citing strong quarterly performance and long-term growth potential through its pipeline of immune system therapies.Goldman’s move came on the heels of Apellis’ second-quarter earnings report, which showed total revenue of $178 million.&nbsp;Syfovre, the company’s treatment for geographic atrophy,&nbsp;generated $151 million in U.S. net product sales,&nbsp;representing a 6% quarter-over-quarter&nbsp;increase in injection volume. Despite a $13 million revenue impact due to increased free sample usage linked to co-pay assistance constraints, the product maintained a dominant market position with over 60% share of new GA patient starts.&nbsp;Empaveli contributed $20.8 million in sales, supported by high compliance rates.The FDA’s recent approval of Empaveli for patients aged 12 and older with C3G and IC-MPGN added another major catalyst. Backed by Phase 3 Valiant trial data, the decision cleared the way for Empaveli’s use in two rare kidney diseases that impact approximately 5,000 patients in the U.S.&nbsp;The trial showed a 68% drop in urinary protein levels, steady kidney function, and clearance of C3 deposits, which are key indicators of kidney health. The label also includes patients with post-transplant recurrence of C3G.Analyst sentiment has improved notably in recent weeks. Citi raised its price target to $46 from $41, calling Empaveli “best-in-class” and a potential growth driver. Scotiabank lifted its target to $22, highlighting confidence in the company’s ability to execute on the Empaveli launch. Baird, BofA, and Morgan Stanley also issued upward revisions earlier this month.Apellis also strengthened its balance sheet through a $300 million royalty agreement with Sobi, selling 90% of future ex-U.S. royalties on Aspaveli, the ex-U.S. brand of Empaveli, for $275 million upfront.&nbsp;The deal includes a $25 million milestone tied to potential EMA approval for the new kidney indications later this year.On Stocktwits, retail sentiment was ‘extremely bullish’ late Thursday amid a 72% surge in 24-hour message volume.<a href="https://stocktwits.com/symbol/APLS">Apellis’ stock</a> has declined 32.6% so far in 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

Retail chatter around Apellis Pharmaceuticals (APLS) spiked Thursday after Goldman Sachs raised its price target to $26 from $24. (Photo credit: Getty Images)

Retail Buzz Surges For Apellis As Goldman Hikes Price Target After Solid Syfovre Sales, FDA Win For Kidney Drug

Goldman Sachs cited Apellis’ 6% quarterly injection growth for Syfovre and potential market upside from Empaveli’s newly approved indications in C3G and IC-MPGN, despite recent revenue headwinds from co-pay assistance constraints.

Apellis Pharmaceuticals (APLS) Reports Q2 Earnings: What Key Metrics Have to Say

The headline numbers for Apellis Pharmaceuticals (APLS) give insight into how the company performed in the quarter ended June 2025, but it may be worthwhile to compare some of its key metrics to Wall Street estimates and the year-ago actuals.

Repligen (RGEN) Lags Q2 Earnings Estimates

Repligen (RGEN) delivered earnings and revenue surprises of -7.50% and +3.56%, respectively, for the quarter ended June 2025. Do the numbers hold clues to what lies ahead for the stock?

Retail buzz around Apellis Pharmaceuticals&nbsp;intensified on Monday after the FDA approved Empaveli,&nbsp;clearing the way for its use in treating two rare kidney diseases that often lead to kidney failure.&nbsp;The drug is now approved for patients 12 and older with C3G and IC-MPGN, which are conditions that affect 5,000 people in the U.S.&nbsp;The decision was backed by data from the Phase 3 Valiant trial, where patients on Empaveli saw a 68% drop in protein levels in their urine, a key sign of kidney stress, along with steady kidney function and signs that harmful C3 deposits were being cleared.&nbsp;The label also includes patients with post-transplant recurrence of C3G.The FDA decision comes amid a flurry of Wall Street updates on Apellis. Earlier this month, Baird raised its price target on Apellis to $50 from $47, updating its model ahead of second-quarter earnings and noting competitive developments in the C3G space.Morgan Stanley and BofA also raised their price targets, now at $26 and $24, respectively.&nbsp;BofA maintained a ‘Neutral’ rating and noted that Apellis has not provided sales guidance for Syfovre, its treatment for geographic atrophy. Morgan Stanley maintained an ‘Equal Weight’ rating and cited the royalty purchase agreement with Sobi.Apellis recently struck a $300 million royalty deal with Sobi, selling 90% of its future ex-U.S. royalties from Aspaveli, its treatment for a rare blood disorder called paroxysmal nocturnal hemoglobinuria (PNH), to strengthen its cash position.Apellis will receive $275 million upfront and may earn another $25 million if Aspaveli is approved for C3G and IC-MPGN in Europe.On Stocktwits, retail sentiment for Apellis was ‘extremely bullish’ amid a 2,350% surge in 24-hour message volume.<a href="https://stocktwits.com/symbol/APLS">Apellis’ stock</a> has declined 43.5% so far in 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

Chronic kidney disease, computer illustration and light micrograph. The illustration shows the gross anatomy of kidneys with chronic glomerulonephritis. | Image source: Getty Images

Why Retail Investors Are Turning Sharply Bullish On Apellis Pharmaceuticals 

The FDA approved Apellis’ drug Empaveli for two rare kidney diseases, following strong results from a Phase 3 trial. 

Axsome Therapeutics (AXSM) Expected to Beat Earnings Estimates: Can the Stock Move Higher?

Axsome (AXSM) possesses the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.

Sanofi's Gene Therapy for Eye Disease Gets FDA's Fast Track Tag

SNY's SAR446597, a one-time intravitreal gene therapy, secures FDA fast track tag for geographic atrophy due to age-related macular degeneration.

Apellis Stock Rises on $300M Royalty Deal With Sobi for Aspaveli

APLS stock jumps after inking a $300M royalty deal with Sobi for Aspaveli, bolstering its cash position and pipeline prospects.

Why Is Kodiak Sciences (KOD) Up 10.5% Since Last Earnings Report?

Why Is Apellis Pharmaceuticals (APLS) Up 7.2% Since Last Earnings Report?

Apellis Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company, which engages in the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs. Its products include EMPAVELI and SYFOVRE. The company was founded by Candace Rose Depp, Pascal Deschatelets, Cedric Francois, and Alec Machiels on September 25, 2009 and is headquartered in Waltham, MA.

Fiscal Period	Estimated	Reported	Surprise	Result
Q3 '25	$1.59	--	--	N/A
Q2 '25	-$0.48	-$0.33	31.64%	BEAT
Q1 '25	-$0.35	-$0.74	-109.74%	MISSED
Q4 '24	-$0.36	-$0.29	19.47%	BEAT
Q3 '24	-$0.29	-$0.46	-55.96%	MISSED

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