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Costco Wholesale Corp. engages in the provision of operation of membership warehouses through wholly owned subsidiaries. It operates through the following geographical segments: United States, Canada, and Other International Operations. The company was founded by James D. Sinegal and Jeffrey H. Brotman in 1983 and is headquartered in Issaquah, WA.

Costco Wholesale Corp

Costco's earnings are a major point of discussion, with investors closely monitoring membership trends and potential impacts from tariffs, as well as debate about whether the company is currently overvalued. The community is actively discussing the potential for a stock split and speculating on the direction the stock will take after the earnings release. Some traders are positioning themselves for a move based on technical indicators, while others are focused on consumer spending and the broader economic outlook.

Cipher Mining, Inc. operates as a Bitcoin mining ecosystem in the United States. The firm is developing a cryptocurrency business. The company was founded in 2021 and is headquartered in New York, NY.

Cipher Mining Inc

CIFR is trending following news of a significant AI hosting agreement with Fluidstack, backstopped by Google; however, the stock price reaction is negative due to concerns about a simultaneous announcement of a convertible note offering. Community discussions revolve around whether the Google backing validates the company's direction, or if dilution from the offering outweighs the positive news. Some traders believe that the dip is a buying opportunity, while others are concerned about the potential impact of dilution.

N2OFF, Inc. is a clean tech company engaged in sustainable solutions for energy and innovation for agri- tech. It delivers integrated solutions for sustainable energy, greenhouse gas emissions reduction and safety, quality solutions for the agri- tech market. Its products include SpuDefender and FreshProtect. The SpuDefender is designed to control the post-harvest potato sprout. The FreshProtect is designed to control spoilage-creating microorganisms on post-harvest citrus fruit. The firm operates through the following segments: Pathogen prevention and prolong shelf life and N2O emissions Global warming solutions. N2OFF was founded by Nimrod Ben-Yehuda on April 1, 2009 and is headquartered in Neve Yarak, Israel.

N2OFF Inc.

NITO is trending due to the recent shareholder approval of a merger with a drug discovery company, sparking mixed reactions within the community. While some investors are optimistic about the potential of the merger and the stock's low float, others are wary of potential dilution and allegations of the company's ties to past scams. The community is actively discussing the implications of the merger, dilution and potential price targets.

Bitcoin is the first successful internet money based on peer-to-peer technology; whereby no central bank or authority is involved in the transaction and production of the Bitcoin currency. It was created by an anonymous individual/group under the name, Satoshi Nakamoto. The source code is available publicly as an open source project, anybody can look at it and be part of the developmental process.  Bitcoin is changing the way we see money as we speak. The idea was to produce a means of exchange, independent of any central authority, that could be transferred electronically in a secure, verifiable and immutable way. It is a decentralized peer-to-peer internet currency making mobile payment easy, very low transaction fees, protects your identity, and it works anywhere all the time with no central authority and banks.  Bitcoin is designed to have only 21 million BTC ever created, thus making it a deflationary currency. Bitcoin uses the SHA-256 hashing algorithm with an average transaction confirmation time of 10 minutes. Miners today are mining Bitcoin using ASIC chip dedicated to only mining Bitcoin, and the hash rate has shot up to peta hashes.  Being the first successful online cryptography currency, Bitcoin has inspired other alternative currencies such as Litecoin, Peercoin, Primecoin, and so on.  The cryptocurrency then took off with the innovation of the turing-complete smart contract by Ethereum which led to the development of other amazing projects such as EOS, Tron, and even crypto-collectibles such as CryptoKitties.

Bitcoin

Bitcoin is experiencing volatility as traders react to economic data and potential market corrections. Community discussions revolve around identifying key support levels and whether the recent dip is a buying opportunity or a sign of a larger downturn. Some are pointing to the influence of macroeconomic factors and liquidations in the crypto market.

Intel Corp. engages in the design, manufacture, and sale of computer products and technologies. It delivers computer, networking, data storage, and communications platforms. The firm operates through the following segments: Client Computing Group (CCG), Data Center and AI (DCAI), Network and Edge (NEX), Mobileye, Accelerated Computing Systems and Graphics (AXG), Intel Foundry Services (IFS), and All Other. The CCG segment consists of platforms designed for notebooks, 2-in-1 systems, desktops, tablets, phones, wireless and wired connectivity products, and mobile communication components. The DCAI segment delivers solutions to cloud service providers and enterprise customers, along with silicon devices for communications service providers and high-performance computing customers. The NEX segment offers computing system solutions from inflexible fixed-function hardware to general-purpose compute, acceleration, and networking devices running cloud native software on programmable hardware. The Mobileye segment develops driving assistance and self-driving solutions. The AXG segment provides products and technologies designed to help customers solve the toughest computational problems. Its products include CPUs for high-performance computing and GPUs targeted for a range of workloads and platforms, from gaming and content creation on client devices to delivering media and gaming in the cloud, and the most demanding high-performance computing and AI workloads on supercomputers. The IFS segment refers to full stack solutions created from the foundry industry ecosystem. The All Other segment represents results from other non-reportable segments and corporate-related charges. The company was founded by Robert Norton Noyce and Gordon Earle Moore on July 18, 1968 and is headquartered in Santa Clara, CA.

Intel Corp.

Intel Corp

Fueled by reports of potential partnerships with tech giants like Apple and TSMC, Intel is experiencing a surge, with the community buzzing about a possible turnaround. Investors are closely watching for further developments and gauging the long-term potential, as many see this as the start of a significant uptrend. Some are locking in profits, while others are holding, anticipating even greater gains.

Concentrix Corp. engages in the provision of customer experience solutions and technology. The company was founded in 1973 and is headquartered in Newark, CA.

Concentrix Corp.

Concentrix Corporation

Concentrix ($CNXC) is trending due to a significant after-hours drop following lowered FY25 EPS guidance, despite narrowing revenue outlook. Community discussions revolve around whether the sell-off is an overreaction, with some citing the company's low forward P/E ratio as a reason to hold. Option traders are seeing straddle opportunities amid the volatility.

BlackBerry Ltd. engages in the provision of intelligent security software and services. It operates through the following segments: Cybersecurity, Internet of Things (IoT), and Licensing and Other. The Cybersecurity segment includes the brand Cylance, BlackBerry Spark, AtHoc, and SecuSUITE. The IoT segment focuses on software licenses, support, maintenance, and professional services. The Licensing and Other segment involves the intellectual property licensing arrangements and settlement awards. The company was founded by Michael Lazaridis, James Laurence Balsillie, and Douglas E. Fregin on March 7, 1984 and is headquartered in Waterloo, Canada.

BlackBerry Ltd

BlackBerry is trending amid community speculation about ticker suppression on certain platforms ahead of earnings, with some users noticing unusual behavior regarding the TSX ticker. Despite the concerns, many investors remain bullish, anticipating positive earnings and discussing the company's partnerships and growth potential in the cybersecurity and IoT sectors, particularly highlighting QNX technology. The community is closely watching for a breakout, fueled by expectations of a strong earnings report.

Crinetics Pharmaceuticals, Inc. operates as a clinical stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. Its product candidate, CRN00808, is an oral nonpeptide somatostatin agonist for the treatment of acromegaly. The firm is also developing other oral nonpeptide somatostatin agonists for neuroendocrine tumors and hyperinsulinism, as well as an oral nonpeptide ACTH antagonist for the treatment of Cushing's disease. The company was founded by R. Scott Struthers, Yun-Fei Zhu and Stephen F. Betz in 2008 and is headquartered in San Diego, CA.

Crinetics Pharmaceuticals Inc

Traders are actively monitoring $CRNX amidst a recently announced public offering and upcoming catalysts, with community chatter focused on potential price manipulation and the actions of major institutional players. Anticipation surrounds the closing of the offering, as some speculate on whether the stock will maintain its elevated levels or experience a pullback. Community members are weighing the potential for a short squeeze against the likelihood of a price correction.

BlackRock Institutional Trust Company N.A. - iShares Silver Trust

iShares Silver Trust

SLV is trending as silver prices reach levels not seen in over a decade, sparking community excitement and discussions about potential further gains. The community is actively debating factors like industrial demand, dollar strength, and the potential for a short squeeze, while some analysts point to silver's undervaluation compared to gold. Broader economic concerns, such as rising debt and potential stagflation, are also fueling interest in silver as a safe haven asset.

Snap, Inc. operates as a technology company, which engages in the provision of a visual messaging application that was created to help people communicate through short videos and images. The company was founded by Frank Reginald Brown IV, Evan Thomas Spiegel, and Robert C. Murphy in 2010 and is headquartered in Santa Monica, CA.

Snap Inc - Ordinary Shares - Class A

Snap Inc

SNAP is experiencing high trading volume amid speculation around a potential TikTok deal and whispers of a possible acquisition, with community members actively debating the impact of these events. Discussions range from potential partnerships and buyouts to the influence of key investors and the app's appeal to younger generations. The high volume and price volatility reflect the uncertainty and anticipation surrounding SNAP's future.

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Shares of aTyr Pharma, Inc. (ATYR) plummeted 82% in Monday’s pre-market after the company announced that its late-stage study of Efzofitimod in 268 patients with pulmonary sarcoidosis did not meet the primary goal of steroid dose reduction from baseline at week 48.However, clinical benefit for Efzofitimod was observed across multiple study parameters, the company <a target="_blank" rel="noopener noreferrer nofollow" href="https://investors.atyrpharma.com/news-releases/news-release-details/atyr-pharma-announces-topline-results-phase-3-efzo-fittm-study">said</a>. aTyr Pharma announced that it plans to engage with the U.S. Food and Drug Administration (FDA) to review the results and determine the path forward for Efzofitimod in the treatment of pulmonary sarcoidosis.On Stocktwits, retail sentiment around <a href="https://stocktwits.com/symbol/ATYR">ATYR stock</a> jumped from 'bullish' to 'extremely bullish' territory over the past 24 hours, while message volume stayed at 'extremely high' levels.&nbsp;Pulmonary sarcoidosis is an inflammatory disease characterized by the formation of clumps of inflammatory cells in one or more organs of the body. It can cause permanent loss of lung function in some patients. According to the company, about 200,000 Americans live with the condition. A total of 268 patients with pulmonary sarcoidosis were enrolled in the late-stage study.The company stated that the change from baseline in mean daily oral corticosteroid dose was reduced to an average of 2.79 mg for 5.0 mg/kg Efzofitimod, compared to 3.52 mg for the placebo in the trial. Complete steroid withdrawal was achieved for 52.6% of patients treated with 5.0 mg/kg efzofitimod vs 40.2% on placebo, it added.The study, however, showed clinical improvement in the King’s Sarcoidosis Questionnaire (KSQ)-Lung score at week 48 for 5.0 mg/kg Efzofitimod compared to placebo. The questionnaire is designed to assess the impact of sarcoidosis on various aspects of life. Further, lung function was maintained at week 48, the company said. aTyr believes these findings indicate drug activity for Efzofitimod.ATYR stock is down 70% this year and approximately 43% over the past 12 months.&nbsp;Read also: <a href="https://stocktwits.com/news-articles/markets/equity/trump-fed-rate-cut-this-week-too-late-powell-bigger-than-he-had-in-mind/chwwONNRdUh">Trump Says ‘Too Late’ Powell Must Cut Rates Now, And ‘Bigger Than He Had In Mind’ Ahead Of Fed Meeting This Week</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Why Is aTyr Stock Falling Today?

The company announced that it plans to engage with the U.S. Food and Drug Administration (FDA) to review the results and determine the path forward for Efzofitimod in the treatment of pulmonary sarcoidosis.

Equity

Atyr Pharma shares fell 1.5% in volatile premarket trade on Monday, with investors on edge ahead of topline results from its pivotal Phase 3 EFZO-FIT trial of efzofitimod. The data is expected any day and will be presented at the European Respiratory Society conference.The 52-week global study, which completed its last patient visits in July, enrolled 268 pulmonary sarcoidosis patients across 85 centers in nine countries. Patients were randomized to monthly intravenous doses of efzofitimod at 3 mg/kg, 5 mg/kg, or placebo.&nbsp;The primary endpoint is steroid reduction from baseline to week 48, with secondary endpoints including symptom relief and lung function. The trial design incorporated a forced steroid taper, a key measure for assessing clinical benefit.Analysts have flagged the readout as a potential inflection point. Jefferies lifted its price target to $17 from $9 last month, citing encouraging earlier-stage data and estimating a 60% probability of statistical success. H.C. Wainwright reiterated a ‘Buy’ rating with a $35 target, Cantor Fitzgerald reaffirmed ‘Overweight’ citing strong statistical power to show steroid reduction, and Leerink Partners maintained an ‘Outperform’ rating with a $16 target.CEO Sanjay Shukla said completing EFZO-FIT, the largest interventional study ever conducted in sarcoidosis, was a milestone for patients who currently rely heavily on corticosteroids despite serious side effects.&nbsp;The company is also studying efzofitimod in systemic sclerosis-related interstitial lung disease in its ongoing Phase 2 EFZO-CONNECT trial.Atyr reported second-quarter results in August with cash, equivalents and investments of $83.2 million as of June 30. Subsequent to the quarter, it raised about $30.7 million through an at-the-market offering.&nbsp;The company said the balance is sufficient to fund operations for a year beyond the EFZO-FIT readout. R&amp;D expenses were $15.4 million in the quarter, driven by trial and manufacturing costs, while G&amp;A expenses totaled $4.9 million.On Stocktwits, retail sentiment was ‘bullish’ amid ‘extremely high’ message volume.One user described the range of possible outcomes as a “bear case” of $2 if the data disappoints, a “base case” of $10–$15 on decent results, and a “bull case” of $25–$35 if topline data are strong enough to spark a squeeze.<stembedurl>https://stocktwits.com/Phantom_Dancer/message/628638414</stembedurl>Another user said they had bought $2 call contracts to limit downside risk, noting that the position would cover losses if the stock fell toward $1.50 while leaving room to benefit if a short squeeze drove the shares higher.<stembedurl>https://stocktwits.com/navyvet1234/message/628639974</stembedurl><a href="https://stocktwits.com/symbol/ATYR">Atyr Pharma’s stock</a> has risen 66.6% so far in 2025.For updates and corrections, email newsroom[at]stocktwits[dot]com.

Atyr Pharma’s stock (ATYR) has risen 66.6% so far in 2025. (Photo credit: Getty Images)

Why Is Atyr Pharma Stock Slipping Premarket?

Investors braced for imminent Phase 3 EFZO-FIT trial results of efzofitimod, with analysts calling it a key inflection point.

5 Biotech Stocks with Highly Anticipated Pending Results

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Biotech M&A is heating up, making small-cap firms with breakthrough assets top acquisition targets and potential big winners for investors.

aTyr Pharma, Inc. engages in the discovery and development of medicines based on novel biological pathways. Its product pipeline includes ATYR1923, ATYR2810, NRP2 mAbs, and AARS-1, DARS-1. The company was founded by Paul Schimmel, Xiang-Lei Yang and Bruce Beutler on September 8, 2005 and is headquartered in San Diego, CA.

Atyr Pharma Inc

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Current Price	$0.8933
Prev Close	$0.951
Open	$0.934
Dividend Yield	0.00%
50-Day Moving Average	$4.66
Beta	0.67
Avg. Volume	3.84M
PE Ratio	-1.19

52-Week High	$7.29
52-Week Low	$0.945
Market Capitalization	$93.19M
EPS (Annual)	-$0.8621
Price to Book	1.18
Revenue Per Employee	$3,983.05
Enterprise Value/EBITDA	N/A

ATYR
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