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Bitcoin is the world's first decentralized cryptocurrency, created in 2009 by the pseudonymous Satoshi Nakamoto. It enables peer-to-peer electronic cash transactions without intermediaries like banks or governments, operating on a blockchain secured by Proof of Work mining and the SHA-256 cryptographic algorithm.   With a fixed supply cap of 21 million coins and programmatic halvings every four years that reduce miner rewards, Bitcoin is designed as a deflationary digital asset often called "digital gold." Its value stems from solving the double-spending problem without trusted intermediaries, creating the first truly scarce digital asset with censorship resistance and permissionless access that no government, corporation, or individual can control.  Bitcoin operates as a decentralized peer-to-peer network where transactions are recorded on a public ledger called the blockchain, distributed across thousands of computers globally. Transactions are grouped into blocks added approximately every 10 minutes through mining, where specialized computers compete to solve complex mathematical puzzles.   Bitcoin has achieved mainstream adoption through multiple vectors. The January 2024 SEC approval of 11 spot Bitcoin ETFs opened Bitcoin investment to traditional finance participants, and corporations like Strategy (formerly MicroStrategy) are using Bitcoin as a treasury reserve asset to protect against currency debasement, offering MSTR holders amplified exposure to Bitcoin.   The Bitcoin ecosystem continues to evolve with innovations like Ordinals, which emerged in January 2023 to enable NFT-like functionality directly on Bitcoin, and BRC-20 tokens, an experimental standard for creating fungible tokens using Ordinal inscriptions. BTCFi (Bitcoin Finance) represents emerging financial applications extending beyond Bitcoin's traditional role, with protocols like Babylon allowing Bitcoin holders to stake BTC to secure Proof of Stake chains.

Bitcoin

A substantial price drop for Bitcoin has triggered widespread liquidations, fueling a highly divided community discussing potential market manipulation and whether this signals a further collapse or a major buying opportunity, alongside speculation about a hawkish Federal Reserve nomination.

Sandisk Corp. engages in the development, manufacture, and provision of storage devices and solutions based on NAND flash technology. Its products include solid state drives, memory cards, and USB flash drives. The company was founded on February 5, 2024 and is headquartered in Milpitas, CA.

Sandisk Corp

SanDisk is trending due to a blowout earnings report and significantly raised guidance, fueled by robust demand for NAND flash memory from AI infrastructure builders. The community is intensely debating a massive short squeeze and FOMO, with bulls anticipating continued upside from strong pricing power and long-term AI partnerships, while bears caution of extreme overvaluation and a potential bubble.

GameStop Corp. engages in offering games and entertainment products through its ecommerce properties and stores. The firm’s stores and ecommerce sites operate primarily under the names GameStop, EB Games, and Micromania. It operates through the following geographical segments: United States, Canada, Australia, and Europe. The company was founded by Daniel A. DeMatteo in 1996 and is headquartered in Grapevine, TX.

Gamestop Corporation - Ordinary Shares - Class A

GameStop Corp

GameStop is trending as CEO Ryan Cohen is reportedly eyeing major acquisitions with the company's substantial cash reserves, fueling widespread community speculation about potential targets and future growth, even as some debate the immediate impact on the stock's price action.

SoFi Technologies, Inc. is a financial service platform, which engages in the provision of student loan refinancing options to the private student loan market. It operates through the following segments: Lending, Technology Platform, and Financial Services. The Lending segment offers personal loans, student loans, home loan products, and related servicing activities. The Technology Platform segment focuses on technology products and solutions revenue. The Financial Services segment includes the SoFi Money product, SoFi Invest product, SoFi Credit Card product, SoFi Relay personal finance management product, and other financial services such as lead generation and content for other financial services institutions. The company was founded in 2011 and is headquartered in San Francisco, CA.

SoFi Technologies Inc

SoFi Technologies is experiencing high anticipation ahead of its earnings report, with community discussions fiercely debating if an expected strong beat and confident guidance will finally reverse the recent downturn attributed to dilution and market manipulation, or if a customary post-ER sell-off will again overshadow positive results.

Microsoft Corp. engages in the development and support of software, services, devices, and solutions. It operates through the following segments: Productivity and Business Processes, Intelligent Cloud, and More Personal Computing. The Productivity and Business Processes segment is composed of products and services relating to productivity, communication, and information services such as Office Commercial, Office Consumer, LinkedIn, and Dynamics business solutions. The Intelligent Cloud segment consists of public, private, and hybrid server products and cloud services for businesses and developers, as well as enterprise and partner services. The More Personal Computing segment refers to products and services including Windows operating system, Windows cloud services, Surface, HoloLens, personal computer accessories, Xbox hardware, Xbox Cloud Gaming, Microsoft News, and Microsoft Edge. The company was founded by Paul Gardner Allen and William Henry Gates, III in 1975 and is headquartered in Redmond, WA.

Microsoft Corporation

Microsoft Corp

Microsoft is experiencing its most significant stock decline in years following its latest earnings report, driven by investor concerns over slowing Azure cloud growth and rising AI capital expenditures. This has ignited a passionate debate within the community, with many viewing the sharp dip as an oversold opportunity for a long-term investment, while others remain wary of the tech giant's immediate future amid broader market caution.

TechCreate Group Ltd. is a holding company, which engages in the provision of technology consultancy and software solutions. The firm also offers payment, cybersecurity, and digital services. Its business areas consist of professional services, software and maintenance licenses, and hardware solutions. The company was founded by Lim Heng Hai, Lau Kok Fong and Ronald Vong in 2015 and is headquartered in Singapore.

TechCreate Group Ltd. - Ordinary Shares - Class A

TechCreate Group Ltd. (TCGL) is trending after an unprecedented and dizzying price spike, with the company stating it is unaware of any material information behind the extreme volatility. The community is actively discussing a potential short squeeze fueled by the stock's low float and high insider ownership, drawing parallels to other explosive, highly speculative runs.

Palantir Technologies, Inc. engages in the business of building and deploying software platforms that serve as the central operating systems for its customers. It operates through the Commercial and Government segments. The Commercial segment focuses on customers working in non-government industries. The Government segment is involved in providing services to customers that are the United States government and non-United States government agencies. Its platforms are widely used in areas such as defense, intelligence, healthcare, energy, and financial services, supporting data integration, large-scale analytics, and operational decision-making. The company was founded by Alexander Ceadmon Karp, Peter Andreas Thiel, Stephen Cohen, Joseph Lonsdale, and Nathan Dale Gettings in 2003 and is headquartered in Denver, CO.

Palantir Technologies Inc - Ordinary Shares - Class A

Palantir Technologies Inc

Palantir is facing significant community debate over its controversial government contracts, particularly with ICE, and a broader software sector downturn, leading to divided sentiment as bulls anticipate an earnings rebound while bears highlight persistent overvaluation.

MEME COIN: $ROAR is the OG token. Est. Sept '22. Inspired by The Roaring Kitty Who Inspired other to fight against wall street through Game Stop.  We Are  100% community-owned.  LP burnt.  Contract Renounced  Ready to Moon like $GME &amp; $AMC?

Roaring Kitty

Roaring Kitty Token ($ROAR) is trending as its community rallies around renewed bullish sentiment for GameStop ($GME), fueled by anticipation of Keith Gill's online activity, recent GameStop financial updates like Bitcoin acquisition, and persistent rumors of a major exchange listing. Holders are actively discussing $ROAR's community-owned model and its potential to follow $GME's movements, believing in a significant price surge.

Chainlink is the industry-standard decentralized oracle network that solves the "oracle problem" by connecting smart contracts with real-world data. Blockchains cannot access external information on their own, so Chainlink acts as a secure bridge, enabling smart contracts to react to real-world events using verified, tamper-proof data. It is widely considered one of the first decentralized oracle networks and is the market leader in bringing off-chain data on-chain.  The platform operates through a decentralized network of nodes that fetch, validate, and deliver data to smart contracts. When a contract requests information like a stock price, a committee of independent nodes retrieves and aggregates the data to reach consensus, then delivers a single trustworthy answer. Chainlink offers a suite of services including Data Feeds for asset prices, CCIP for cross-chain token transfers and messaging, Automation for triggering smart contract functions, and Proof of Reserve for verifying asset collateralization.  Chainlink has established itself as critical infrastructure for both DeFi and institutional adoption, with partnerships including Swift, Euroclear, Mastercard, UBS, ANZ, Fidelity International, and J.P. Morgan. Its institutional products include the Chainlink Runtime Environment for tokenized asset workflows, Confidential Compute for privacy-preserving computation, and the Automated Compliance Engine for embedding regulatory rules into smart contracts.  The LINK token is the native asset used to pay node operators for services, fund subscription accounts, and incentivize network security through staking. Node operators stake LINK as collateral, which can be slashed if they provide inaccurate data. Chainlink was co-founded in 2017 by Sergey Nazarov and Steve Ellis, who co-authored the white paper with Ari Juels, and raised $32 million in its September 2017 ICO.

ChainLink

Chainlink is trending due to anticipation around its Grayscale ETF launch and expanding institutional integrations for real-world asset tokenization, fostering strong long-term conviction among proponents, even as others express frustration over its historical price underperformance relative to its foundational utility.

Apple, Inc. engages in the design, manufacture, and sale of smartphones, personal computers, tablets, wearables and accessories, and other varieties of related services. It operates through the following geographical segments: Americas, Europe, Greater China, Japan, and Rest of Asia Pacific. The Americas segment includes North and South America. The Europe segment consists of European countries, as well as India, the Middle East, and Africa. The Greater China segment comprises China, Hong Kong, and Taiwan. The Rest of Asia Pacific segment includes Australia and Asian countries. Its products and services include iPhone, Mac, iPad, AirPods, Apple TV, Apple Watch, Beats products, AppleCare, iCloud, digital content stores, streaming, and licensing services. The company was founded by Steven Paul Jobs, Ronald Gerald Wayne, and Stephen G. Wozniak in April 1976 and is headquartered in Cupertino, CA.

Apple Inc

Apple's record-breaking Q1 earnings, fueled by strong iPhone and Services revenue and a surge in China sales, are sparking intense discussion as the stock's surprisingly muted after-hours movement leads to community theories of options manipulation and "sell-the-news" profit-taking, amidst warnings of rising memory costs.

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Notable ETF Outflow Detected - IWM, BE, CRDO, KTOS

Looking today at week-over-week shares outstanding changes among the universe of ETFs covered at ETF Channel, one standout is the iShares Russell 2000 ETF (Symbol: IWM) where we have detected an...

<ul class="summary-bullets"><li>Innodata stated that in its new partnership with Palantir, the company will provide the latter with specialized annotation and data engineering for thousands of hours of rodeo video footage.</li><li>The company stated that this project will enable the use of computer vision technologies to detect skeleton joints, riders, and animals.</li><li>This will help Innodata to calculate performance metrics and display them in activities such as bull riding, bronc riding, bareback riding, and barrel racing.</li></ul>Innodata Inc. (INOD) shares rose more than 14% in Thursday’s opening trade after the company announced a new partnership with Palantir Technologies Inc. (PLTR).Innodata announced that it has been chosen by Palantir to provide high-quality training data and data engineering services. This partnership is aimed at supporting Palantir’s AI-enabled platforms for rodeo event analysis.<h2 class="st-heading-2">What Will Innodata Offer Palantir?</h2>Innodata stated that in its new partnership with Palantir, the company will provide the latter with specialized annotation and data engineering for thousands of hours of rodeo video footage.The company stated that this project will enable the use of computer vision technologies to detect skeleton joints, riders, and animals. This will help Innodata to calculate performance metrics and display them in activities such as bull riding, bronc riding, bareback riding, and barrel racing.Palantir announced a partnership with TWG AI in December 2025 to bring real-time AI and computer vision to rodeo in a bid to improve the experience of athletes and fans of the sporting event.“Palantir's requirements validate the investments we have made in domain-expert annotation, end-to-end generative-AI workflow enablement, rigorous quality systems, and secure global operations,” said Innodata Federal’s Senior Vice President, Vinay Malkani.Palantir’s Head of Machine Learning, Dimitrios Lymperopoulos, stated that the partnership with Innodata will help the company scale its computer vision and geospatial analytics capabilities.<h2 class="st-heading-2">How Stocktwits Users Reacted</h2>Retail sentiment on Stocktwits around&nbsp;<a href="https://stocktwits.com/symbol/INOD">Innodata</a> was in the ‘bullish’ territory. The stock was the fifth most trending ticker on the platform at the time of writing.One bullish user expressed optimism about the company’s fourth-quarter (Q4) earnings report due in the coming weeks, following the Palantir partnership.<stembedurl>https://stocktwits.com/AI_Bull_/message/643272283</stembedurl>Another user called the Palantir partnership “well deserved news” for the company.<stembedurl>https://stocktwits.com/DoubleEE/message/643271429</stembedurl><a href="https://stocktwits.com/symbol/INOD">INOD stock</a> is up 20% year-to-date and 79% over the past 12 months.Also See:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/why-is-cvna-stock-rising-today/cmyiXnNR4KY">CVNA Stock Rebounds After Analysts Call Carvana Short Report 'Significant Misrepresentation Of Facts'</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, the Innodata logo is seen displayed on a smartphone and in the background. 

INOD Stock Is Rising Today — What Is Its New Partnership With Palantir About?

Innodata announced that it has been chosen by Palantir to provide high-quality training data and data engineering services.

Equity

<ul class="summary-bullets"><li>The company said that the FDA hold has impacted two experimental gene therapies, RGX-111 and RGX-121.</li><li>REGENXBIO added that the tumor was identified during a routine brain MRI of an asymptomatic five-year-old participant in its RGX-111 trial.</li><li>The company said that the participant had received intracisternal RGX-111 four years prior.</li></ul>REGENXBIO Inc.’s (RGNX) shares tumbled more than 29% in Wednesday’s&nbsp;opening trade after the company announced an update from the U.S. Food and Drug Administration (FDA).REGENXBIO stated that the FDA has placed a clinical hold on the company’s experimental gene therapy program for the treatment of rare childhood diseases.The company said that the FDA hold has impacted two experimental gene therapies, RGX-111 and RGX-121.<h2 class="st-heading-2">Why Did FDA Place A Clinical Hold?</h2>REGENXBIO stated that the FDA’s clinical hold was placed after a brain tumor was found in one patient in the trial.The company added that the tumor was identified during a routine brain magnetic resonance imaging (MRI) of an asymptomatic five-year-old participant in its RGX-111 trial. REGENXBIO said that the participant had received intracisternal RGX-111 four years prior.The company said that an investigation into whether this serious adverse event (SAE) is drug-related is ongoing, and that causality has not been established yet.While the SAE involved a patient in the RGX-111 trial, the FDA has also placed a hold on the RGX-121 gene therapy, citing the similarities in products, study populations, and shared risk between the clinical studies, the company said.“These are separate therapies, and the positive safety profile of RGX-121 in more than 30 patients treated, including those dosed nearly seven years ago, remains unchanged,” said REGENXBIO CEO Curran Simpson.<h2 class="st-heading-2">What Did REGENXBIO’s Experimental Therapies Treat?</h2>The RGX-111 gene therapy is aimed at treating MPS I, also known as Hurler syndrome. This is a genetic disorder that results in the buildup of large sugar molecules in lysosomes, causing damage to several organ systems.The RGX-121 gene therapy is aimed at treating MPS II, also known as&nbsp;Hunter syndrome, which results in the buildup of large sugar molecules in body tissues. This causes abnormalities in body organs, including the heart, skeleton, and respiratory system.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment on Stocktwits around&nbsp;<a href="https://stocktwits.com/symbol/RGNX">REGENXBIO</a> was in the ‘bearish’ territory, with message volumes at ‘extremely high’ levels at the time of writing.One user thinks that the stock decline is an “overreaction.”<stembedurl>https://stocktwits.com/Longbuy1/message/643122172</stembedurl><a href="https://stocktwits.com/symbol/RGNX">RGNX stock</a> is down 34% year-to-date, but up 25% over the past 12 months.Also See:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/trump-signals-military-escalation-toward-iran-as-markets-brace-for-big-tech-earnings-fed-decision/cmygPjOR40T">Trump Signals Military Escalation Toward Iran As Markets Brace For Big Tech Earnings, Fed Decision</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Trading digital board showing the data on global stock market crash. | Image source: Getty Images

RGNX Stock Is Falling Today — What Is The FDA Update On REGENXBIO's Gene Therapy?

REGENXBIO stated that the FDA has placed a clinical hold on the company’s experimental gene therapy program for the treatment of rare childhood diseases.

<ul class="summary-bullets"><li>Florida Atlantic University commits $20 million to purchase and install a D-Wave Advantage2 annealing system.</li><li>D-Wave to establish its new corporate headquarters at the Boca Raton Innovation Center.</li><li>D-Wave is expected to showcase new hybrid solver capabilities using machine learning in quantum workflows at the Qubits 2026 conference later on Tuesday.</li></ul>Shares of D-Wave Quantum Inc. (QBTS) drew significant retail interest on Tuesday morning after rising over 5% in pre-market trading, fueled by fresh updates including a defense partnership and a deal with Florida Atlantic University.D-Wave Quantum announced that Florida Atlantic University (FAU) has committed $20 million to purchase and install a D-Wave Advantage2 annealing system at its Boca Raton campus, with deployment expected later in 2026.&nbsp;This system will serve as the foundation for a new collaboration between D-Wave and FAU, which could include a Quantum Applications Academy and support for research, training, and workforce development initiatives.&nbsp;D-Wave will also establish its new corporate headquarters at the Boca Raton Innovation Center.<h2 class="st-heading-2">More Collaborations</h2>In a separate announcement, D-Wave revealed a collaboration with Davidson Technologies and defense company Anduril Industries to develop quantum-classical hybrid applications for complex U.S. air and missile defense scenarios.Initial proof-of-concept tests using D-Wave’s Stride hybrid solver on the Advantage2 system demonstrated up to 10x faster solutions, a 9-12% improvement in threat mitigation, and the ability to intercept 45-60 additional missiles in a simulated 500-missile attack.The collaboration will expand to other defense challenges, including logistics, manufacturing, cyber defense, and course-of-action planning, the company added.At D-Wave’s Qubits 2026 conference later on Tuesday, the company is expected to showcase new hybrid solver capabilities using machine learning in quantum workflows, as well as progress on its technologies following the acquisition of Quantum Circuits earlier this month.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment on Stocktwits turned ‘bullish’ from ‘neutral’ a day earlier, amid ‘high’ message volumes. <a href="https://stocktwits.com/symbol/QBTS">QBTS</a> was among the top trending tickers on the platform.<img src="https://news.stocktwits-cdn.com/QBTS_jpg_8dd9a289c0.webp" alt="QBTS.jpg">One Stocktwits user sounded skeptical and highlighted the stock’s current valuation.<stembedurl>https://stocktwits.com/Shelby007/message/642988665</stembedurl>The stock has gained more than 300% over the past year, even as year-to-date declines stand at around 12%.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/ups-stock-rises-q4-beat-strong-2026-guidance/cmyavvvR4Le">UPS Stock Rises Pre-Market On Upbeat Guidance – CEO Calls 2026 As Inflection Year After Amazon Pullback</a> For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, D-Wave Systems Inc. logo of a Canadian quantum computing company is seen on a smartphone screen.

What Triggered QBTS Stock’s Pre-Market Rally Today?

The company tied up with Davidson Technologies and defense company Anduril Industries to develop quantum-classical hybrid applications for U.S. air and missile defense scenarios.

<ul class="summary-bullets"><li>The revised label provides clearer starting-dose guidance for adult patients switching from multiple daily injections or insulin pump therapy.</li><li>The update is supported by clinical results from the Dose Optimization study and the INHALE-3 trial.</li><li>Previously, MannKind filed a supplemental FDA application to expand Afrezza’s use to patients aged four to 17, with a decision anticipated by May 29, 2026.</li></ul>Shares of MannKind Corp. (MNKD) gained more than 7% in pre-market trading on Monday after the company announced that the U.S. Food and Drug Administration (FDA) approved an update to the prescribing information for Afrezza, its inhaled mealtime insulin used to improve glycemic control in adult patients with diabetes mellitus.The revised label provides clearer starting-dose guidance for adult patients switching from multiple daily injections or insulin pump therapy. The update is supported by clinical results from the Dose Optimization study and the INHALE-3 trial, which showed significantly improved post-meal glucose control after conversion to Afrezza, as recommended by the new dosing recommendations.“We expect that this label update will help support healthcare providers by providing clearer starting dose guidance when transitioning patients to inhaled insulin from subcutaneous mealtime insulin—whether injections or insulin pumps. We believe this refinement to the label helps support appropriate initiation of therapy while reinforcing Afrezza’s established clinical profile,” said Kevin Kaiserman, Senior Vice President, Therapeutic Area Head, Diabetes at MannKind Corporation.&nbsp;<h2 class="st-heading-2">Q3 Revenue Boosted By Afrezza Sales</h2>In November, the company posted a 17% increase in third-quarter (Q3) total revenue to $82.13 million, driven by strong growth in sales of its Afrezza inhaled insulin. Afrezza revenue climbed 23% to $18.5 million, supported by higher pricing and rising demand, while royalty income rose to $33.3 million.MannKind also submitted a supplemental application to the FDA seeking approval of Afrezza for patients aged four to 17. A regulatory decision is expected by May 29, 2026.<h2 class="st-heading-2">How Did Retail React?</h2>Retail sentiment for <a href="https://stocktwits.com/symbol/MNKD">MNKD</a> on Stocktwits remained in the ‘bullish’ zone over the past 24 hours, accompanied by ‘high’ message volumes. MNKD was among the top trending tickers at the time of writing.<figure class="image"><img src="https://news.stocktwits-cdn.com/MNKD_jpg_fd37ecdc2d.webp" alt="MNKD.jpg" width="930" height="85"><figcaption>MNKD's Sentiment Meter and Message Volumes at Premarket on Jan. 26, 2026 | Source: Stocktwits</figcaption></figure>Meanwhile, one user didn’t see the FDA update as a major catalyst.<stembedurl>https://stocktwits.com/firefox2778/message/642859216</stembedurl>The stock has declined around 4.7% year-to-date and over 10.5% in the past year.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/ag-asml-hl-stocks-soar-silver-prices-record-high-110/cmy78kuR4WC">AG, ASM, HL Stocks Soar Pre-Market As Silver Blasts Past $110</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Mannkind Corp and the company's inhalable insulin product. Company employee demonstrating how the device is used. (Photo by Lawrence K. Ho/Los Angeles Times via Getty Images)

Why Did MNKD Stock Jump Over 7% In Pre-Market Today?

The U.S. FDA approved an update to the prescribing information for Afrezza inhalation powder to treat adults with diabetes mellitus.

MNKD Stock Gets A Pre-Market Boost From FDA Label Revision For Afrezza

Should iShares Russell 2000 ETF (IWM) Be on Your Investing Radar?

<ul class="summary-bullets"><li>The offering includes 34.8 million shares at $5.75, the stock’s closing price on Tuesday.</li><li>Medtronic’s investment is expected to give it a post-offering ownership stake of between 16% and 19.99%.</li><li>Proceeds from the transactions will be used to support Anteris’ clinical strategy, including&nbsp; R&amp;D at v2vmedtech.</li></ul>Shares of Anteris Technologies Global Corp. (AVR) jumped sharply in pre-market trading on Wednesday after the structural heart specialist unveiled a $200 million equity raise alongside a sizable strategic investment from healthcare technology heavyweight Medtronic.<a href="https://stocktwits.com/symbol/AVR">AVR shares</a> were up around 17% at the time of writing and were on track to open at their highest levels since March 2025.Anteris announced a proposal to raise $200 million via a public offering of its common stock and grant underwriters a 30-day option to purchase up to an additional $30 million of shares at the public offering price.In a separate release, the company said the offer is to sell around 34.8 million shares at $5.75, the stock’s closing price on Tuesday.<h2 class="st-heading-2">Medtronic Investment</h2>Alongside the public offering, Anteris entered into a stock purchase agreement with Medtronic plc (MDT). Under the deal, Medtronic, through a wholly owned unit, will invest up to $90 million in Anteris common stock via a private placement priced in line with the public offering. The transaction is expected to give Medtronic a post-offering ownership stake of between 16% and 19.99% in Anteris.Proceeds from the transactions will be used to support Anteris’ clinical strategy, including continued patient recruitment and execution of the global PARADIGM pivotal trial for the DurAVR Transcatheter Heart Valve (THV) in severe aortic stenosis, expanding manufacturing capacity, and funding ongoing research and development (R&amp;D) at v2vmedtech, a privately owned medical technology company.The DurAVR THV is a biomimetic valve designed to mimic the performance of a healthy aortic valve.&nbsp;<h2 class="st-heading-2">What Is Retail Saying?</h2>On Wednesday, retail sentiment for AVR flipped to ‘extremely bullish’ from ‘bearish’ a day earlier, while message volumes increased to ‘extremely high’ from ‘normal’ on Stocktwits. AVR was among the top trending tickers on the platform at the time of writing.<img src="https://news.stocktwits-cdn.com/AVR_jpg_6c056947d5.webp" alt="AVR.jpg">One user expects the stock to hit $20 on the ‘bullish news’.<stembedurl>https://stocktwits.com/Redrooster79/message/642383722</stembedurl>However, another user was slightly skeptical about the dilution.<stembedurl>https://stocktwits.com/Rvazstocksfl/message/642363903</stembedurl>AVR stock has declined more than 4% over the past year but has gained around 12% so far in 2026.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/why-is-nvidia-stock-rising-in-premarket-today/cmUDZxrR4Oz">Why Is Nvidia Stock Rising In Premarket Today?</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Rising chart and reflection of business buildings: stock photo courtesy of Yuichiro Chino via Getty Images

Why Did AVR Stock Surge Pre-Market Today? 

The company unveiled a $200 million dilution alongside a $90 million investment from healthcare technology heavyweight Medtronic.

AVR Stock Pops Pre-Market: Medtronic Backs $200M Capital Raise To Fund Key Trial

Relative Strength: Identifying Alpha in Market Weakness

The stocks that refuse to drop in a tough market are often the ones that will lead the next leg higher. By utilizing relative strength, investors can identify the best long opportunities. 

<ul class="summary-bullets"><li>The deal provides Novavax with an upfront payment of $30 million, along with the opportunity to earn up to $500 million in additional development and sales milestones.</li><li>Matrix-M adjuvant is a proprietary vaccine ingredient, used in several marketed vaccines to improve effectiveness and help the immune system better recognize and remember disease targets.</li><li>Novavax is eligible to receive tiered royalties in the high mid-single digit range on sales of any Pfizer products that use Matrix-M.</li></ul>Novavax, Inc. (NVAX) shares climbed 6% higher in pre-market trading on Tuesday after the company signed a licensing agreement with Pfizer, granting the pharmaceutical giant non-exclusive rights to use Novavax’s Matrix-M adjuvant in up to two disease areas.Matrix-M adjuvant is a proprietary vaccine ingredient that improves the body’s immune response. It is made from naturally derived compounds and is used in several marketed vaccines to improve effectiveness and help the immune system better recognize and remember disease targets, according to Novavax.<h2 class="st-heading-2">What Is The Novovax-Pfizer Deal?</h2>The deal provides Novavax with an upfront payment of $30 million, along with the opportunity to earn up to $500 million in additional development and sales milestones. Novavax is also eligible to receive tiered royalties in the high mid-single digit range on sales of any Pfizer products that use Matrix-M.Under the agreement, Pfizer will take full responsibility for the development and commercialization of its products, while Novavax will supply the Matrix-M adjuvant. The partnership strengthens Novavax’s long-term revenue potential.This comes after Novavax completed the transfer of U.S. and European marketing authorizations for its COVID-19 vaccine, Nuvaxovid, to Sanofi in November. The move resulted in a second $25 million milestone payment to Novavax, following the completion of the European Union marketing authorization transfer in October 2025.Novavax is expected to receive additional milestone payments and royalties tied to Nuvaxovid, Sanofi-developed combination products, and new vaccines that use Novavax’s Matrix-M adjuvant. Novavax also has long-standing partnerships with Japan’s Takeda and the Serum Institute of India.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment for <a href="https://stocktwits.com/symbol/NVAX">NVAX</a> on Stocktwits remained in the ‘extremely bullish’ zone, amid ‘extremely high’ message volumes. NVAX was also among the top three trending tickers on the platform at the time of writing.<img src="https://news.stocktwits-cdn.com/NVAX_jpg_1f4183eedd.webp" alt="NVAX.jpg">One bullish user said that the stock is undervalued.<stembedurl>https://stocktwits.com/ejaXstoXX/message/642272237</stembedurl>Another user was bullish about Matrix-M’s market potential.<stembedurl>https://stocktwits.com/P38FTD/message/642271830</stembedurl>The stock has declined around 6% over the past year.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/why-ivf-stock-soaring-premarket/cmUum0oR4ap">INVO Fertility’s 350% Spike Puts Microcap IVF Stocks Back On Retail Radar</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, a medical syringe is displayed on a screen, and the logo of Novavax in the background. (Photo Illustration by Nikos Pekiaridis/SOPA Images/LightRocket via Getty Images)

Why NVAX Stock Is Popping Pre-Market – And What Does Pfizer Have To Do With It?

The company signed a licensing agreement with Pfizer, granting it non-exclusive rights to use Matrix-M adjuvant in up to two disease areas.

NVAX Stock Rises Pre-Market As Pfizer Licenses Its Vaccine Technology

<ul class="summary-bullets"><li>ANKTIVA is an Interleukin-15 (IL-15) receptor agonist that helps develop and activate key cells that work to destroy cancer cells.</li><li>The company presented an overview of the clinical status of its papillary disease program, including more than five years of follow-up data.</li><li>The data demonstrated strong bladder preservation outcomes.</li></ul>ImmunityBio (IBRX) shares rose 6% in pre-market trading on Tuesday after the United States Food and Drug Administration (FDA) outlined a pathway for resubmitting its supplemental biologics license application (sBLA) for ANKTIVA in Bacillus Calmette Guérin (BCG)-unresponsive papillary bladder cancer, without requesting new trials.&nbsp;The company said it recently met with the FDA for a Type B end-of-phase meeting to review data spanning over five years.<h2 class="st-heading-2">The FDA Meeting</h2>During the meeting, ImmunityBio presented more than five years of follow-up data supporting the papillary disease indication. Long-term results, published in The Journal of Urology, showed bladder cancer–specific survival of around 96% at three years, with median survival not yet reached.The data also demonstrated strong bladder preservation outcomes, with cystectomy avoidance rates of 92% at one year and 82% at three years, alongside a safety profile consistent with ANKTIVA’s currently approved use in carcinoma in situ (CIS).Based on these discussions, the FDA recommended that ImmunityBio submit additional information for further evaluation to potentially support a resubmission of the sBLA initially filed in 2025. The Agency did not request any new clinical trials.“We have completed the assembly and analysis of the requested additional information and will submit it within the next 30 days for the Agency’s review,” said Richard Adcock, President and CEO of ImmunityBio.ANKTIVA is an Interleukin-15 (IL-15) receptor agonist. IL-15 is an immune system protein that helps develop and activate key cells that work to destroy cancer cells. It is already commercially available in the U.S. for NMIBC CIS, with or without papillary tumors, and has received approvals in the U.K. and Saudi Arabia, as well as conditional approval in the European Union.<h2 class="st-heading-2">How Did Stocktwits Users React?</h2>Retail sentiment on Stocktwits for <a href="https://stocktwits.com/symbol/IBRX">IBRX</a> remained in the ‘extremely bullish’ territory over the past 24 hours, amid ‘extremely high’ message volumes. IBRX was among the top trending tickers on the platform at the time of writing.<img src="https://news.stocktwits-cdn.com/IBRX_jpg_704152379c.webp" alt="IBRX.jpg">One user laid out the potential triggers for the stock.<stembedurl>https://stocktwits.com/end2war/message/642249657</stembedurl>Over the past year, the stock has gained 85,% and year-to-date, it has added more than 173%.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/why-did-rapt-stock-surge-63-in-pre-market-today/cmUuK0vR4aO">Why Did RAPT Stock Surge 63% In Pre-Market Today?</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, an ImmunityBio company logo is seen displayed on a smartphone screen. (Photo Illustration by Piotr Swat/SOPA Images/LightRocket via Getty Images)

IBRX Stock Extends Rally On FDA Feedback For ANKTIVA Bladder Cancer Filing

The company said it recently held end-of-phase talks with the United States Food and Drug Administration on its ANKTIVA application for treatment-resistant papillary bladder cancer.

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