Exchange: NASDAQ·Updated 10:27 AM EDT
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PALI Palisade Bio Inc

$1.17
$0.03
(2.50%)
Today
Mkt Cap$209.12M
Vol631,913.00

About PALI

Palisade Bio, Inc. (Nasdaq: PALI) is a clinical-stage biopharmaceutical company advancing a next-generation oral PDE4 inhibitor prodrug designed to improve pharmacology, tolerability and convenience for patients with inflammatory and fibrotic diseases. Through its differentiated prodrug platform and precision pharmacology strategy, Palisade Bio is committed to transforming proven PDE4 biology into better, safer oral therapies for patients living with chronic inflammatory and fibrotic diseases. The Company’s lead program, PALI-2108, is a once-daily oral PDE4 inhibitor prodrug designed to be selectively bioactivated in the ileum and colon, initiating targeted PDE4 inhibition at sites of disease while enabling systemic distribution of the active drug. PALI-2108 has demonstrated positive results in a Phase 1a and two Phase 1b clinical trials, including studies in ulcerative colitis (UC) and fibrostenotic Crohn’s Disease (FSCD). Palisade Bio is now advancing towards two Phase 2 clinical studies in UC and Crohn’s disease (CD).
50

Neutral Sentiment

How do you feel about PALI?

LordWorld
$PALI The market has already digested the UEG data and is now in wait-and-see mode for real validation. The current price of ~$1.20 reflects exactly that: skepticism toward early signals + a long wait until the key data. The main catalyst is 2H 2027 (12-week ASCENTRA-UC data). If it confirms activity (especially with the biomarker and hints of an effect on fibrosis), the re-rating potential will be very large. If not — a sharp downward revaluation. This is a classic high-risk / high-reward clinical-stage biotech with roughly a 12-month horizon until the main answer.The UEG news is essentially not new. • The price targets are a bet on success in ~12 months. Additional risk: further dilution remains possible if the company needs to raise more capital before the Phase 2 readouts. 🟩✅ On November 12, positive news regarding MDXH will emerge. Keep an eye on this stock and buy MDXH.
2
ronburgandy75
$PALI interesting UEGW. They are showcasing their product well. Phase 2 data would be the litmus test. Tolerability and pharmacokinetics are well established.
2
Rayvio_News_Filter
$PALI 🏥 Palisade Bio, Inc. reported Phase 1b Crohn’s disease data for PALI-2108 showing a 47.5% reduction in mean endoscopic disease activity and a 58.8% reduction in mean fecal calprotectin after 14 days, alongside translational evidence. Market-relevant event
1
YouVSYou
$PALI had news maybe a bounce at 1.32 $YMAT 2.36 keybreak. $HTZ no more fun Unless 2.10/2.29 above
CorderoArkus
$PALI Each earning I am doing in scalping is to accumulate more and more $PALI. Once approved and commercialize we will be above 10USD. 3-4 years... I can wait...

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