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Ethereum is a global, open-source platform for decentralized applications. In other words, it is a decentralized blockchain platform that enables developers to build and deploy smart contracts and applications without central authority control. Unlike Bitcoin, which primarily functions as digital currency, Ethereum operates as a programmable global computer where developers can create any type of decentralized service.   The platform hosts over $14 billion in DeFi applications with hundreds of thousands of active users across financial protocols, NFT marketplaces, and gaming platforms. Its transition to Proof of Stake in September 2022 reduced energy consumption by over 99%, addressing environmental concerns while strengthening network security.  The network operates through thousands of independent validator nodes that process transactions and execute smart contracts on the Ethereum Virtual Machine. Smart contracts are self-executing programs written in Solidity that automatically carry out agreements when conditions are met, eliminating intermediaries like banks or brokers.   Validators stake ETH as collateral to propose and validate blocks, earning rewards for honest participation while facing penalties for malicious behavior. The EIP-1559 upgrade introduced a dynamic base fee mechanism that burns ETH with each transaction, creating deflationary pressure during high network activity when more ETH is burned than issued to validators.  Vitalik Buterin proposed Ethereum in 2013, but seven co-founders helped build it, including Gavin Wood who created Solidity and the EVM technical specification, and Joseph Lubin who founded ConsenSys. The project launched in July 2015 after raising over $18 million through crowdfunding, quickly becoming the largest blockchain developer community. Major milestones include the 2020 Beacon Chain launch, the 2021 London hard fork implementing fee burning, and the 2022 Merge to Proof of Stake.   Ether (ETH) serves multiple functions: paying transaction fees (gas), staking to secure the network and earn 3-5% annual yields, serving as collateral in DeFi protocols, and purchasing NFTs and digital assets. The asset is increasingly adopted by traditional institutions, with publicly traded companies adding ETH to corporate treasuries to generate staking yields while maintaining blockchain exposure, and in 2024, the SEC approved spot Ethereum ETFs, allowing traditional investors to gain exposure through conventional brokerage accounts.  Ethereum's roadmap focuses on dramatically increasing transaction capacity to over 100,000 per second, reducing confirmation times, and enhancing decentralization while maintaining security against future threats like quantum computing.

Ethereum

Ethereum is currently navigating a period of heightened volatility as the market balances institutional ETF inflows against ongoing geopolitical tensions surrounding the Strait of Hormuz. Investors remain focused on critical price support levels while monitoring whether ongoing diplomatic negotiations will resolve regional conflicts or lead to further market instability.

Maulcoin

Maulcoin is capturing significant attention as the community rallies around its organic growth and aggressive 'Sith-themed' branding, with supporters actively pushing for higher market capitalization milestones and celebrating the avoidance of a rug-pull structure. Traders are focused on the stock's strong community-driven momentum and volume spikes, viewing current price action as a consolidation period before the next major leg up.

What Is Tezos (XTZ)?   Tezos is a high-performing blockchain and open-source platform for assets and applications, with a strong focus on code security, on-chain governance, and decentralization. Tezos 2.0, the upcoming step in the evolution of Tezos, aims to improve scalability (via layer 2s), composability, and to implement support to mainstream programming languages (like Javascript, Typescript, Python, and many others).   Initially built with formal verification in mind, the Tezos protocol enables builders to avoid bugs when developing smart contracts, making it particularly suited to applications that require a high degree of security and certainty.   Tezos’ LPoS (Liquid Proof-of-Stake) consensus mechanism enables any stakeholder to take part, directly or by delegation, in the consensus process, and to be rewarded for securing the network. Rather uniquely, Tezos’ on-chain governance system also enables stakeholders to create and vote on protocol upgrade proposals. This pioneering system allows the protocol to self-amend and upgrade itself without leading to a split (or fork) in the blockchain, empowering the community without slowing down innovation.   First proposed in 2014 and launched in 2018, the Tezos Mainnet has a proven track record of running uninterrupted ever since, having earned a strong reputation for technical excellence and a supportive community.    Who Are the Founders of Tezos? Tezos was conceived by Arthur and Kathleen Breitman in a 2014 white paper under the pseudonym L.M. Goodman in a nod to Satoshi Nakamoto, referencing a journalist who had misidentified the creator of Bitcoin.   In a previous paper, the Breitmans had argued that Bitcoin's biggest shortcomings were the lack of a governance process that invited contributions from its community of users, cost and centralization issues raised by its proof-of-work system, the limited expressiveness of its programming language which didn’t allow for smart contracts, and security

Tezos

Tezos (XTZ) is facing intense social media debate, with investors divided between those viewing recent price volatility as a setup for a potential recovery and vocal detractors warning of an "epic dump." The community is heavily focused on technical resistance levels and macroeconomic catalysts, such as the potential impact of the Clarity Act and broader altcoin market trends.

Back in 2011, long before “crypto Twitter”, NFTs, or VC-backed chains existed, users of the BitcoinTalk forum came up with a new currency - not to launch a network, but to make fun of btc.... and so: The first memecoin/memecurrency was born.  On May 23, 2011, a Something Awful poster cracked, “Has anyone called them buttcoins yet?”. It was sophomoric and perfect. Within weeks the gag metastasized into Buttcoin.org, a parody blog that described a “peer to peer butt” economy while cataloging mining fiascos, exchange blowups, and MLM-adjacent “innovations”.

Buttcoin

Buttcoin is surging in popularity as the community rallies around its status as a foundational meme asset with deep historical roots, positioning it as an irreverent rival to traditional crypto. Investors are actively debating its potential to reach multi-billion market capitalizations, fueled by its aggressive branding and active promotion across social channels.

Bitcoin is the world's first decentralized cryptocurrency, created in 2009 by the pseudonymous Satoshi Nakamoto. It enables peer-to-peer electronic cash transactions without intermediaries like banks or governments, operating on a blockchain secured by Proof of Work mining and the SHA-256 cryptographic algorithm.   With a fixed supply cap of 21 million coins and programmatic halvings every four years that reduce miner rewards, Bitcoin is designed as a deflationary digital asset often called "digital gold." Its value stems from solving the double-spending problem without trusted intermediaries, creating the first truly scarce digital asset with censorship resistance and permissionless access that no government, corporation, or individual can control.  Bitcoin operates as a decentralized peer-to-peer network where transactions are recorded on a public ledger called the blockchain, distributed across thousands of computers globally. Transactions are grouped into blocks added approximately every 10 minutes through mining, where specialized computers compete to solve complex mathematical puzzles.   Bitcoin has achieved mainstream adoption through multiple vectors. The January 2024 SEC approval of 11 spot Bitcoin ETFs opened Bitcoin investment to traditional finance participants, and corporations like Strategy (formerly MicroStrategy) are using Bitcoin as a treasury reserve asset to protect against currency debasement, offering MSTR holders amplified exposure to Bitcoin.   The Bitcoin ecosystem continues to evolve with innovations like Ordinals, which emerged in January 2023 to enable NFT-like functionality directly on Bitcoin, and BRC-20 tokens, an experimental standard for creating fungible tokens using Ordinal inscriptions. BTCFi (Bitcoin Finance) represents emerging financial applications extending beyond Bitcoin's traditional role, with protocols like Babylon allowing Bitcoin holders to stake BTC to secure Proof of Stake chains.

Bitcoin

Bitcoin is currently caught in a volatile tug-of-war as investors closely monitor stalled U.S.-Iran diplomatic talks, with the community split between those betting on a short-term price correction and others aggressively accumulating during the uncertainty. The asset remains a focal point of intense debate, as traders weigh geopolitical risk against the broader narrative of institutional inflows and its evolving role as a sanctioned-economy tool.

Hyperliquid is a layer one (L1) blockchain best known for perpetual futures and spot trading. Beyond its flagship DEX trading platform, the ecosystem supports borrowing, lending, real world assets (RWAs), and a full-fledged Ethereum Virtual Machine (EVM), making it a leading force in decentralized finance (defi).   Just as electronic trading dramatically improved markets in the 2000s, Hyperliquid offers an opportunity for a massive technical upgrade of the existing financial system through a transparent, efficient, and resilient blockchain. HYPE is the native token of the Hyperliquid blockchain, with a maximum supply of 1 billion.

Hype

HYPE is currently trending as a centerpiece of the decentralized perpetual exchange market, with community discussion centered on its high-volume ecosystem and potential for future institutional adoption. Traders are actively tracking its momentum against other crypto assets and discussing strategic entry points, driven by recent exchange listings and the ongoing narrative of HYPE serving as a 'house of all finance' within the DeFi space.

Flutter Entertainment Plc engages in the business of online betting and gaming. It operates through the following segments: UK and Ireland, Australia, International, and US. The UK and Ireland segment includes the operations of Sky Betting and Gaming, Paddy Power, Betfair, and tombola. The Australia segment focuses on sports betting services provided to Australian customers online. The International segment relates to poker, casino, rummy, lottery, and sports betting. The US segment includes sports betting, daily fantasy sports, and gaming services. The company was founded in 1988 and is headquartered in New York, NY.

Flutter Entertainment Plc

Flutter Entertainment is seeing heightened trading activity amid ongoing market debate over whether its upcoming 'FanDuel Predicts' platform can effectively fend off competition from emerging prediction markets like Kalshi and Polymarket. Investors are closely monitoring regulatory headlines and bipartisan legislative efforts to restrict non-traditional sports betting as the company navigates a transition into a more crowded wagering landscape.

Innodata, Inc. is a data engineering company, which engages in providing artificial intelligence software platforms and management of its services. It operates through the following business segments: Digital Data Solutions (DDS), Synodex, and Agility. The DDS segment combines deep neural networks and human expertise in multiple domains to make unstructured information useable. The Synodex segment enables clients in the insurance and healthcare sectors to transform medical records into useable digital data and to apply technologies to the digital data to augment decision support. The Agility segment provides tools and related professional services that enable public relations and communications professionals to discover influencers, amplify messages, monitor coverage, and measure the impact of campaigns. The company was founded by Todd H. Solomon in 1988 and is headquartered in Ridgefield Park, NJ.

Innodata Inc

Innodata is currently trending due to active discussions regarding the stock's consolidation phase and its potential as a takeover target within the AI data training sector. Community sentiment remains split between long-term investors highlighting the company's profitability and partnerships with defense and tech majors, and traders closely monitoring technical support levels amid broader market corrections.

Assertio Holdings, Inc. is a commercial pharmaceutical company, which engages in acquisitions, licensing, and mergers. The firm focuses on portfolio of neurology, inflammation, and pain medications. Its products include INDOCIN, Sympazan, Otrexup, SPRIX, CAMBIA, and Zipsor. The company was founded on August 7, 1995 and is headquartered in Lake Forest, IL.

Assertio Holdings Inc

Assertio Holdings is facing intense shareholder scrutiny and frustration following a surprise acquisition agreement with Garda Therapeutics, with investors questioning the deal's valuation and potential conflicts of interest. The community is actively discussing the possibility of blocking the tender offer, coordinating with major shareholders, and investigating the timeline of the board's decision-making process.

Halliburton Co. engages in the provision of products and services to the energy industry. It operates through the Completion and Production, and Drilling and Evaluation segments. The Completion and Production segment focuses on cementing, stimulation, specialty chemicals, intervention, pressure control, artificial lift, and completion products and services. The Drilling and Evaluation segment provides field and reservoir modeling, drilling, fluids, evaluation, and wellbore placement solutions that enable customers to model, measure, drill, and optimize well construction activities. The company was founded by Erle P. Halliburton in 1919 and is headquartered in Houston, TX.

Halliburton Co.

Halliburton is seeing heightened market attention driven by expectations of a revival in U.S. investment in Venezuelan energy infrastructure and broader geopolitical tensions that have bolstered the energy sector. Investors are actively discussing the stock's potential for a long-term uptrend while weighing operational risks, with bullish sentiment supported by aggressive call option activity and institutional interest in energy infrastructure resilience.

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<ul class="summary-bullets"><li>Sellas will present new data on its CDK9 inhibitor SLS009 at the American Association for Cancer Research (AACR) meeting on April 21.</li><li>Preclinical findings showed SLS009 triggered leukemia cell death by increasing caspase-3 activity and reducing survival proteins such as MCL-1 and survivin.</li><li>Investor focus remains centered on the Phase 3 Regal study evaluating GPS as a maintenance therapy for AML patients in remission after relapse.</li></ul>Shares of Sellas Life Sciences Group, Inc. (SLS) rose 1% in premarket trading on Thursday as investors positioned ahead of an upcoming cancer conference presentation and a closely watched survival milestone in the company’s Phase 3 acute myeloid leukemia (AML) trial.<a href="https://stocktwits.com/symbol/SLS">SLS stock</a> jumped 8% on Wednesday amid a volatile trading week.<h2 class="st-heading-2">AACR Preview: SLS009 Triggers Leukemia Cell Death Signals</h2>Sellas is preparing to present new preclinical data on its CDK9 inhibitor candidate SLS009 at the American Association for Cancer Research (AACR) annual meeting on April 21 in San Diego.Preclinical findings showed that SLS009 triggered leukemia cell death by increasing&nbsp;the&nbsp;activity of caspase-3, a key apoptosis protein, while lowering survival signals such as MCL-1 and survivin that help cancer cells persist. The drug also became more potent with repeated exposure, with early effects appearing within hours and strengthening over 24 hours.Notably, SLS009 remained active even in AML models carrying ASXL1 and TP53 mutations, which are associated with treatment resistance and poorer outcomes.<h2 class="st-heading-2">Investor Focus Remains On AML Survival Readout Timeline</h2>However, investor attention remains firmly focused on the company’s Phase 3 Regal trial evaluating GPS as a maintenance therapy for AML patients whose disease returned but later entered remission following additional treatment.GPS targets the Wilms Tumor-1 antigen, a protein commonly expressed across leukemia cells regardless of mutation status.The event-driven study will begin final analysis once 80 overall-survival events are recorded. Sellas previously said the contract research organization monitoring the trial had logged 72 events as of Dec. 26, bringing the study closer to the threshold required to initiate topline analysis.CEO Angelos Stergiou recently addressed speculation surrounding the timing of the readout on&nbsp;<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.linkedin.com/feed/update/urn:li:activity:7444461539476197376/?originTrackingId=ExoqDp%2B3Mqnf9Ee3j3DVgA%3D%3D">LinkedIn</a>, noting that slower accumulation of survival events in oncology trials can sometimes indicate patients are living longer than baseline expectations.Once the 80th event occurs, the company plans to proceed with database lock, statistical analysis, unblinding and disclosure of topline results.<h2 class="st-heading-2">How Does Retail Feel About SLS?</h2>On Stocktwits, retail sentiment for SLS has slipped to ‘bearish’ from ‘extremely bullish’ levels a month ago amid a 23% dip in message volumes over the past week.<figure class="image"><img src="https://news.stocktwits-cdn.com/sls_ss_png_d73af252d9.webp" alt="sls ss.png" width="965" height="143"><figcaption>SLS sentiment and message volume as of April 9 | Source: Stocktwits</figcaption></figure>One user&nbsp;<a href="https://stocktwits.com/Princeb/message/649792805">said</a> SLS is “truly shaping up to be a once in a lifetime moonshot win.&nbsp; Don't miss your chance.”<stembedurl>https://stocktwits.com/Princeb/message/649792805</stembedurl>Another user&nbsp;<a href="https://stocktwits.com/Torben96/message/649792114">said</a>, “GPS is a safe harbour now, the IDMC meeting will reveal this. We should be worth 2B Dollar already.”<stembedurl>https://stocktwits.com/Torben96/message/649792114</stembedurl>SLS stock has surged 367% over the past year.For updates and corrections, email newsroom[at]stocktwits[dot]com.Read Next:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/bbby-ceo-pulls-opendoor-into-everything-home-turnaround-bet/cZJgy2ORIrB">Bed Bath &amp; Beyond CEO Pulls Opendoor Into ‘Everything-Home’ Platform Pivot</a>

SLS stock has surged 367% over the past year. (Photo credit: Getty Images)

SLS Stock Rises Premarket Ahead Of Cancer Summit This Month – Investors Eye Phase 3 AML Trial Milestone

SLS Stock - CEO Angelos Stergiou recently said that the slower accumulation of survival events can sometimes reflect longer patient survival.

Equity

CEO Angelos Stergiou recently said that the slower accumulation of survival events can sometimes reflect longer patient survival.

SELLAS Life Sciences Group (NASDAQ:SLS) Stock Price Up 9.5%  - What's Next?

SELLAS Life Sciences Group (NASDAQ:SLS) Trading 9.5% Higher - Here's What Happened...

SELLAS Life Sciences Group (NASDAQ:SLS) Stock Price Down 7.7%  - Here's Why

SELLAS Life Sciences Group (NASDAQ:SLS) Shares Down 7.7% - What's Next...

All You Need to Know About SELLAS Life Sciences Group, Inc. (SLS) Rating Upgrade to Buy

SELLAS Life Sciences Group, Inc. (SLS) has been upgraded to a Zacks Rank #2 (Buy), reflecting growing optimism about the company's earnings prospects. This might drive the stock higher in the near term.

Wall Street Analysts Believe SELLAS Life Sciences Group, Inc. (SLS) Could Rally 63.58%: Here's is How to Trade

The consensus price target hints at a 63.6% upside potential for SELLAS Life Sciences Group, Inc. (SLS). While empirical research shows that this sought-after metric is hardly effective, an upward trend in earnings estimate revisions could mean that the stock will witness an upside in the near term.

<ul class="summary-bullets"><li>Investors weighed conflicting signals from Middle East diplomacy and braced for fresh labor market data.</li><li>AI trade tensions and regulatory risks kept Nvidia and chip-linked names under pressure.</li><li>U.S. President Trump will be holding a cabinet meeting at 10:00 am ET today.&nbsp;</li></ul>U.S. stock futures fell early Thursday as investors continued to parse the geopolitical developments in the Middle East. Amid conflicting reports, Iran is said to be reviewing a U.S. peace proposal delivered through Pakistan. Traders are also bracing for fresh macro signals with jobless claims data due later today. U.S. President Trump will be holding a cabinet meeting at 10:00 am ET today.&nbsp;As of 4:00 a.m. ET on Thursday, Dow, S&amp;P 500, and Nasdaq futures fell 0.4%, and Russell 2000 futures were down 0.6%.Retail sentiment toward the&nbsp;<a href="https://stocktwits.com/symbol/SPY">SPDR S&amp;P 500 ETF (SPY)</a>, an exchange-traded fund that tracks the S&amp;P 500 Index, and the&nbsp;<a href="https://stocktwits.com/symbol/QQQ">Invesco QQQ Trust (QQQ)</a> ETF, which tracks the Nasdaq-100 Index, has been languishing at ‘extremely bearish’ amid high trading volume.&nbsp;Trending Stocks To WatchNvidia (NVDA):&nbsp;The chipmaker remains in focus, with retail sentiment weakening to ‘bearish’ on Stocktwits. Calls are growing louder in Washington, with U.S. Senators Warren and Banks pushing to freeze export licenses over national security concerns.Meta Inc (META):&nbsp;It has lost another lawsuit alleging they made misleading claims about platform safety, adding to its growing list of legal headwinds.Destiny Tech100 (DXYZ):&nbsp;Garnering heavy retail interest as speculation around a potential SpaceX IPO grows this week.Micron (MU), Sandisk (SNDK):&nbsp;Memory stocks took a hit after reports that Google’s new AI model architecture could bring a significant impact on memory requirements.Super Micro (SMCI): The stock remained under pressure as shareholders filed a securities fraud lawsuit following recent allegations of chip smuggling.ImmunityBio (IBRX): The retail favorite biotech stock is back on traders’ radar after the company highlighted progress in its bladder cancer program and expanded trials targeting severe pneumonia and ARDS.&nbsp;Sellas Life Sciences (SLS): This pharma stock is gaining ground amid&nbsp;retail-trader speculation that Pfizer (PFE) may target the firm for an acquisition.urban-Gro (UGRO): The stock fell over 10% in early pre-market trading after surging over 400% in the previous session. Retail is bullish on the company’s new exposure to India’s fast-growing cricket economy following its merger with Flash Sports &amp; Media.Other tickers trending on&nbsp;Stocktwits&nbsp;at the time of writing included Adma Biologics (ADMA), Upstart Holdings (UPST), Moonlake Immunotherapeutics (MLTX), NextDecade Corporation (NEXT), and Alphabet Inc (GOOGL).&nbsp;Other Catalysts To WatchOn the economic front, traders will be watching for the release of continuing jobless claims data at 8:30 am ET. Also keep an eye on commentary from a whole host of Fed Governors’ speeches through the day, including Fed Vice Chair for Supervision Michael Barr.On earnings radar, watch out for quarterly reports from Pulmatrix (PULM), BioRestorative Therapies Inc (BRTX), and POET Technologies Inc (POET), among others, today.&nbsp;For updates and corrections, email newsroom[at]stocktwits[dot]com

Nasdaq, S&P 500 Futures Fall Ahead Of Jobless Claims Data: Why NVDA, META, DXYZ, IBRX, SLS Are Keeping Traders Engaged Today

Data from Stocktwits shows that traders remain ‘extremely bearish’ on SPY and QQQ. 

<ul class="summary-bullets"><li>Investors compared Merck’s willingness to pay a 42% premium for mid-stage leukemia drug TERN-701 with Sellas’ AML pipeline opportunity.</li><li>Several retail investors pointed to Pfizer as a potential buyer, citing its ongoing expansion in hematologic cancers and need for post-COVID growth drivers.</li><li>Attention is focused on the Phase 3 Regal trial of GPS in AML relapse patients, which had recorded 72 of 80 required death events for final analysis as of late December.</li></ul>Shares of Sellas Life Sciences (SLS)&nbsp;jumped over 6% on Wednesday as Merck’s $6.7 billion acquisition of Terns Pharmaceuticals triggered renewed buzz on potential takeover targets across blood-cancer drug pipelines.<a href="https://stocktwits.com/symbol/SLS">SLS stock</a> has risen 41% this quarter and has surged over 300% over the past year.<h2 class="st-heading-2">Merck’s Terns Deal Spurs Leukemia Interest</h2>Merck said it would acquire Terns for $53 per share in cash, representing a 42% premium to the 90-day average before the deal’s announcement.The acquisition adds TERN-701, an oral leukemia drug currently in early-to-mid-stage clinical testing, to Merck’s blood-cancer pipeline. The treatment is being studied for patients with chronic myeloid leukemia whose disease did not respond well to earlier therapies or who could not tolerate them.Now, retail investors are drawing comparisons between Merck’s willingness to pay billions for a mid-stage leukemia asset and the perceived commercial opportunity around Sellas’ pipeline.<h2 class="st-heading-2">Retail Traders Bet On Pfizer As Potential Buyer</h2>On Stocktwits, retail sentiment for SLS has remained in the ‘bearish’ zone over the past week amid an over 350% surge in message volume this quarter. The stock’s watcher base has jumped 20% over the past year.&nbsp;<figure class="image"><img src="https://news.stocktwits-cdn.com/sls_ss_png_7ab67c1205.webp" alt="sls ss.png" width="968" height="144"><figcaption>SLS sentiment and message volume as of March 26 | Source: Stocktwits</figcaption></figure>Sentiment over the past day has increasingly centered on Pfizer as a potential acquirer following the Merck-Terns deal. One trader&nbsp;<a href="https://stocktwits.com/MarcoFla99/message/648580457">said</a>, “My $$ is on PFE to acquire SLS.”The investor pointed to Pfizer’s ongoing clinical work on Mylotarg in CD33-positive acute myeloid leukemia (AML), noting that the company is conducting a prospective surveillance study to evaluate the drug’s safety and effectiveness in newly diagnosed patients as part of its push into hematologic cancers.Another trader argued Pfizer may be seeking a major oncology win following the pandemic-era revenue decline,&nbsp;<a href="https://stocktwits.com/OnTheBalance/message/648587881">saying</a>, “They need a clear win to bury the COVID era and leave it behind… What is better than a cancer moonshot?”Another investor&nbsp;<a href="https://stocktwits.com/OnTheBalance/message/648587881">highlighted</a> motivations behind possible acquisitions, saying “PFE stock and shareholders [are] looking desperately for a powerful boost.”<h2 class="st-heading-2">Retail Traders Run Buyout Valuation Scenarios</h2>One retail investor&nbsp;<a href="https://stocktwits.com/Duncan74/message/648577739">estimated</a> that applying a typical 5x-8x peak-sales multiple to projected revenue of about $5.5 billion for Sellas’ lead AML candidate, Galinpepimut-S (GPS), and $1.2 billion for its CDK9 inhibitor, SLS-009, could imply a valuation range of roughly $33.5 billion to $53.6 billion.Another trader compared the Merck-Terns transaction directly with Sellas’ opportunity: “If TERN was acquired by MRK for 8.8b. and our product has market size smaller than TERN. our upside should be 4x-6x?”A separate user discussed potential acquisition structure scenarios,&nbsp;<a href="https://stocktwits.com/JdlawVT40/message/648584776">saying</a>, “Wouldn’t a PFE stock purchase be sweet. All long term holding period and a 6.30 dividend. Four to one share SLS.”Another trader&nbsp;<a href="https://stocktwits.com/Johnmtnb2018/message/648533707">suggested</a> the setup for a deal may already be in place: “The table is now fully set for interested pharma’s to finish a deal!” One investor also&nbsp;<a href="https://stocktwits.com/Laacy/message/648584092">outlined</a> a portfolio strategy for a possible acquisition, saying, “If PFE offers id sell my options. Keep 33% as pfizer shares if share based and sell the rest.”<h2 class="st-heading-2">GPS Catalyst Aligns With Pfizer Moves</h2>Investor attention remains focused on Sellas’ Phase 3 Regal trial evaluating GPS in AML patients whose cancer returned and then went back into remission after additional treatment. The study is designed to reach its final analysis after 80 patient death events, with 72 recorded as of Dec. 26 while the trial remained fully blinded, placing the program closer to a potential results-driven catalyst.Merck’s move to buy TERN-701 underscores continued demand for blood-cancer assets, while Pfizer has been stepping up investment in oncology as it looks to rebuild growth after the sharp decline in COVID vaccine revenues and increasing competition across several aging products.&nbsp;The company has expanded its cancer pipeline through initiatives including its $1.25 billion upfront licensing deal with 3SBio, ongoing development of Mylotarg in AML and progress with Tukysa in breast cancer.For updates and corrections, email newsroom[at]stocktwits[dot]com.Read Next:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/sls-vs-tern-which-stock-has-more-upside-ahead-of-keytruda-patent-cliff/cZ3YKepRI16">SLS Vs. TERN: Which Pharma Stock Has More Upside As Merck Eyes $6B Cancer Bet Ahead Of Keytruda Patent Cliff</a>

SLS stock has risen 41% this quarter and has surged over 300% over the past year. (Photo credit: Getty Images)

SLS Stock Jumps After Merck's Tern Deal Sparks Buyout Buzz In Blood-Cancer Space: Retail Bets On This Big Pharma Suitor

Merck’s acquisition of Terns underscores strong big-pharma demand for blood-cancer assets, as Pfizer also expands its oncology pipeline.

Medicine pill is seen with Merck logo displayed on a screen in the background in this illustration photo taken in Poland on November 5, 2021. (Photo by Jakub Porzycki/NurPhoto via Getty Images)

SLS Vs. TERN: Which Pharma Stock Has More Upside As Merck Eyes $6B Cancer Bet Ahead Of Keytruda Patent Cliff

SLS vs TERN Stock - Analyst estimates suggest SLS may offer 73% upside, versus 16% for TERN, despite takeover momentum supporting TERN’s shares.

Analyst estimates suggest SLS may offer 73% upside, versus 16% for TERN, despite takeover momentum supporting TERN’s shares.

SELLAS Life Sciences Group (NASDAQ:SLS) Trading Down 8.5%  - Here's Why

SELLAS Life Sciences Group (NASDAQ:SLS) Shares Down 8.5% - Time to Sell...

SELLAS Life Sciences Group (NASDAQ:SLS) Trading Up 12.9% - Here's Why

SELLAS Life Sciences Group (NASDAQ:SLS) Trading Up 12.9% - Here's What Happened...

SELLAS Life Sciences Group, Inc. is a clinical stage biopharmaceutical company, which engages in the development and commercialization of immunotherapeutic for cancer indications. Its product pipeline includes galinpepimut-S. The company was founded by Angelos M. Stergiou on April 3, 2006 and is headquartered in New York, NY.

SELLAS Life Sciences Group Inc

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Investors are closely monitoring the potential for a mid-trial clinical halt by the IDMC based on groundbreaking efficacy data.

A massive accumulation of over 53 million shorted shares is creating high expectations for a violent repricing event.

The upcoming oncology conference is expected to be a major catalyst for company awareness and potential strategic updates.

Discussions are heating up around the potential curative capabilities of proprietary peptide technologies for various cancer indications.

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