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Verastem, Inc. is a biopharmaceutical company, which engages in the development and commercialization of drugs for the treatment of cancer. The company was founded by Richard H. Aldrich, Michelle Dipp, Piyush Gupta, Satish Jindal, Eric S. Lander, Robert F. Weinberg, and Christoph H. Westphal on August 4, 2010 and is headquartered in Needham, MA.

Verastem Inc

Verastems VS-7375 clinical update is the main focus, with the company reporting encouraging KRAS G12D activity, including a 50% confirmed response rate in second-line pancreatic cancer, alongside favorable tolerability. Traders are weighing the results potential against the stocks decline and a newly priced share offering; some view the offering price as investor confidence, while others are concerned about dilution.

CoreWeave, Inc. engages in the powers of the creation and delivery of the intelligence that drives innovation. It offers a solution used by organizations of all sizes that require sophisticated AI computing, from the largest of enterprises to small, well-funded start-ups. The company was founded by Michael Intrator, Brian Venturo, Peter Salanki, and Brannin McBee on September 21, 2017 and is headquartered in Livingston, NJ.

CoreWeave Inc. - Ordinary Shares - Class A

CoreWeave Inc

CoreWeave is under pressure amid a broader AI-infrastructure selloff, as OpenAI revenue disclosures renewed doubts about whether AI demand can support the sectors heavy buildout. Bears are also focused on CoreWeaves debt, capital spending and financing costs, while bulls call the demand concerns overblown and point to its backlog and capacity expansion.

Paramount Skydance Corp. is a next-generation global media and entertainment company that engages in providing content creation and distribution services. It operates through the following business segments: Studios, Direct-to-Consumer, and TV Media. Its portfolio unites brands including Paramount Pictures, Paramount Television, CBS, CBS News, Nickelodeon, MTV, BET, Comedy Central, Showtime, Paramount Plus, Pluto TV, and Skydance’s Animation, Film, Television, Interactive/Games, and Sports divisions. The company is headquartered in New York, NY.

Skydance Corp. - Ordinary Shares - Class B

Skydances distribution of long-dated warrants and the shift to ex-warrant trading dominate discussion, with traders debating whether the share-price adjustment reflects the warrants separated value or additional selling pressure. Concerns about potential dilution and the debt burden from the Warner Bros. Discovery deal add to the bearish reaction, while some holders argue the warrants offset the stocks decline.

Candel Therapeutics, Inc. is a clinical stage biotechnology company, which engages in the development and commercialization of viral immunotherapies. Its pipeline includes CAN-2409 and CAN-3110. The company was founded by Estuardo Aguilar-Cordova in 2002 and is headquartered in Needham, MA.

Candel Therapeutics Inc

Discussion centers on new immune-biomarker findings for Candels CAN-2409 prostate cancer program and the planned BLA submission, with bullish traders viewing the data as support for the treatments potential and regulatory case. Others remain concerned about the stocks decline despite positive updates, BLA timing, and possible dilution, with some also criticizing the CEOs share sale.

Liquidia Corp. operates as a holding company which engages through its subsidiary in developing and commercializing biopharmaceutical products and novel products development used in PRINT technology to transform the lives of patients. The company was founded in June 2004 and is headquartered in Morrisville, NC.

Liquidia Corp

Liquidias settlement with United Therapeutics resolves their litigation and keeps YUTREPIA available for PAH, while the PH-ILD indication is being removed. Traders see relief from the risk of losing access to the market, but debate whether the costly settlement and lost indication outweigh that benefit.

United Therapeutics Corp. is a biotechnology company, which engages in the development and commercialization of products for patients with chronic and life-threatening conditions. Its products include Adcirca, Orenitram, Remodulin, TYVASO, and Unituxin. The company was founded by Martine A. Rothblatt on June 26, 1996 and is headquartered in Silver Spring, MD.

United Therapeutics Corp

United Therapeutics global settlement with Liquidia resolves six lawsuits and keeps YUTREPIA available for PAH while removing its PH-ILD indication, a development traders view as protecting UTHRs Tyvaso franchise. Some posts note that Liquidias continued PAH sales limit the competitive impact, while others question why UTHR shares have reacted modestly to the deal.

GameStop Corp. engages in offering games and entertainment products through its ecommerce properties and stores. The firm’s stores and ecommerce sites operate primarily under the names GameStop, EB Games, and Micromania. It operates through the following geographical segments: United States, Canada, Australia, and Europe. The company was founded by Daniel A. DeMatteo in 1996 and is headquartered in Grapevine, TX.

Gamestop Corporation - Ordinary Shares - Class A

GameStop Corp

CEO Ryan Cohens latest large open-market share purchase, continuing a run of insider buying, is driving attention. Many traders view it as a bullish signal and link it to warrant-related or short-squeeze speculation, while others argue insider purchases alone are not a substitute for meaningful company news.

ASML Holding NV engages in the development, production, marketing, sales, upgrading and servicing of advanced semiconductor equipment systems. It includes lithography, metrology and inspection systems. The company was founded on April 1, 1984 and is headquartered in Veldhoven, the Netherlands.

ASML Holding NV - New York Shares

ASML Holding NV

ASMLs quarterly results and raised full-year sales outlook are driving discussion, with management citing strong AI-related equipment demand that may outstrip planned supply in coming years. Traders are divided over the share-price decline: bulls call it a sell-the-news reaction to solid results and demand, while skeptics point to a slight sales miss and the lack of a 2027 outlook.

Revolution Medicines, Inc. is a clinical-stage precision oncology company, which engages in developing novel targeted therapies. It engages in the discovery and development of cancer treatment by pioneering novel combination and monotherapy treatment regimens to maximize the depth and durability of clinical benefit and circumvent adaptive resistance mechanisms for patients which are dependent on the RAS and mTOR pathway. The company was founded by Mark A. Goldsmith, Kevan Shokat, Martin D. Burke, David L. Pompliano and Michael Fischbach in October 2014 and is headquartered in Redwood City, CA.

Revolution Medicines Inc

FDA review details highlighting a lower response rate for Revolution Medicines daraxonrasib in the KRAS G12D subgroup have fueled scrutiny of the drugs efficacy and contributed to discussion of RVMDs pullback. Traders disagree on how much the subgroup result matters, weighing response rates against survival data and comparing the drug with Verastems competing KRAS G12D program.

SELLAS Life Sciences Group, Inc. is a clinical stage biopharmaceutical company, which engages in the development and commercialization of immunotherapeutic for cancer indications. Its product pipeline includes galinpepimut-S. The company was founded by Angelos M. Stergiou on April 3, 2006 and is headquartered in New York, NY.

SELLAS Life Sciences Group Inc

SELLAS is drawing attention ahead of the final analysis of its Phase 3 REGAL trial in AML, with traders focused on the pending 80th-death milestone and eventual GPS results. Trading and options activity has fueled unconfirmed speculation about a data leak, short covering, or a buyout, while others stress that no trial outcome or deal has been confirmed.

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Prevail Therapeutics is a biotechnology company focused on developing novel gene therapies for patients with Parkinsonâ??s disease and other neurodegenerative diseases. Prevail was launched in 2017 by The Silverstein Foundation for Parkinsonâ??s with GBA, REGENXBIO, and OrbiMed, and is headquartered in New York, NY.

Prevail Therapeutics Inc

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Hold rates steady

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Hike 25 bps

Fed decision day is here - Kevin Warsh chairs his first FOMC meeting with markets pricing a hold at 3.50%-3.75% but watching for a hawkish shift. Vote on what you expect to be decided today, then drop your prediction for the first rate cut or hike in the comments.

What do you expect the Fed to decide at its FOMC meeting today? 
 
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