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Oracle Corp. engages in the provision of products and services that address aspects of corporate information technology environments, including applications and infrastructure technologies. It operates through the following business segments: Cloud and License, Hardware, and Services. The Cloud and License segment markets, sells, and delivers enterprise applications and infrastructure technologies through cloud and on-premise deployment models including cloud services and license support offerings. The Hardware segment provides infrastructure technologies including Oracle Engineered Systems, servers, storage, industry-specific hardware, operating systems, virtualization, management, and other hardware-related software. The Services segment offers consulting, advanced support, and education services. The company was founded by Lawrence Joseph Ellison, Robert Nimrod Miner, and Edward A. Oates on June 16, 1977 and is headquartered in Austin, TX.

Oracle Corp.

Oracle is trending due to a mixed earnings report, with concerns arising from increased spending on AI infrastructure and rising debt despite strong cloud growth and a large backlog. Community discussions revolve around whether Oracle can effectively monetize its AI investments, with some questioning the long-term viability of its strategy, while others see a buying opportunity amid the selloff. The broader market is reacting, with some fearing a potential AI bubble burst.

Mawson Infrastructure Group, Inc. engages in the provision of digital asset infrastructure services. The company was founded on February 10, 2012 and is headquartered in Midland, PA.

Mawson Infrastructure Group Inc

MIGI is trending due to its low float and upcoming conference, where the company may share updates on its shift towards AI and high-performance computing. Community members are discussing potential short squeezes and high price targets, fueled by the company's expanding infrastructure and possible new contracts. Sentiment remains volatile, with traders closely monitoring key price levels and potential catalysts.

Rezolute, Inc. operates as a biopharmaceutical company, which engages in the development of drug therapies for patients with metabolic and orphan diseases. The firm's antibody therapy, ersodetug, is designed to treat all forms of hyperinsulinism. The company was founded by Nevan Charles Elam, Ho Young Huh, and Sankaram Mantripragada in March 2010 and is headquartered in Redwood City, CA.

Rezolute Inc

Rezolute Inc is trending as investors digest the implications of its failed Phase 3 trial for congenital hyperinsulinism, with discussions focusing on the company's remaining cash runway and potential strategic alternatives. The community is debating the stock's valuation relative to its cash reserves, with some speculating about a dead cat bounce or bottom fishing opportunities. Despite the setback, Rezolute's other assets and cash position are generating interest among some investors.

Carvana Co. is a holding company and an eCommerce platform, which engages in the buying and selling of used cars. The company was founded by Ernest Garcia, III, Benjamin Huston and Ryan Keeton in 2012 and is headquartered in Tempe, AZ.

Carvana Co. - Ordinary Shares - Class A

Carvana Co.

Carvana is trending as traders debate whether its S&P 500 inclusion justifies its high valuation, with some calling it a "scam" and others predicting further gains. Community discussions revolve around potential short squeezes, the influence of interest rate cuts, and concerns about the company's fundamentals versus market hype. Despite the debate, the stock's strong upward momentum has captured significant attention.

PayPal Holdings, Inc. engages in the development of technology platforms that enable digital payments and simplifies commerce experiences on behalf of merchants and consumers worldwide. Its solutions include PayPal, PayPal Credit, Braintree, Venmo, Xoom, and Paydiant products. The firm also enables consumers to exchange funds with merchants using funding sources, which include bank account, PayPal account balance, PayPal Credit account, credit, and debit card or other stored value products. It operates through United States and Other Countries geographical segments. The company was founded in December 1998 and is headquartered in San Jose, CA.

PayPal Holdings Inc

PayPal is trending downwards amidst analyst downgrades, most recently from BofA and JP Morgan, with concerns stemming from slowing growth in branded checkout and a perceived lack of management confidence. The community is debating the impact of buybacks, the CEO's performance, and whether the stock is undervalued or a value trap. Some traders express frustration, while others see an opportunity for long-term gains if PayPal can turn things around.

AXIL Brands, Inc. engages in the manufacture, market, sale and distribution of hearing and audio enhancement, and protection products. It operates through the Hearing Enhancement and Protection, and Hair Care and Skin Care segments. The Hearing Enhancement and Protection segment includes ear buds, earmuffs, ear plugs, outdoor speakers, and ear care items. The Hair Care and Skin Care segment focuses on expanding its business-to-business salon sales through its network of domestic and international distributors. The company was founded on May 21, 2015 and is headquartered in Beverly Hills, CA.

AXIL Brands Inc.

AXIL Brands is trending following news of a national retail distribution agreement with Walmart, causing significant premarket gains. The community is actively discussing potential price targets and whether the stock can sustain its momentum, while also considering potential resistance levels. This development marks AXIL's largest retail placement, expanding access to its hearing protection products.

iRobot Corp. is a robot company, which engages in designing and building robots. The firm's products include robot vacuums and maps, and pool cleaners. It operates through Domestic and International geographical segments. The company was founded by Rodney Allen Brooks, Colin M. Angle, and Helen Greiner in August 1990 and is headquartered in Bedford, MA.

Irobot Corp

iRobot Corp

IRBT is trending due to speculation around a potential short squeeze, driven by high short interest and increasing borrow fees, as well as discussion of government support for domestic robotics. The community is debating potential price targets and whether the rally is sustainable, given the company's financial situation. Some traders are also pointing to the stock's low float as a catalyst for further gains.

Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company, which is engaged in the discovery and development of therapeutics for the treatment of rare diseases. The company was founded on July 22, 1980, and is headquartered in Cambridge, MA.

Sarepta Therapeutics Inc

Sarepta Therapeutics is trending due to a recent debt refinancing announcement, sparking mixed reactions within the community. While some view the move as a strategic advantage for potential buyout negotiations and extended financial flexibility, others express concerns about higher interest rates and management's financial decisions. Community members are actively debating the implications of the refinancing on the company's future and potential acquisition prospects.

The Trade Desk, Inc. engages in the provision of a self-service and cloud-based ad-buying platform. It operates through the United States and International geographical segments. The firm offers omnichannel advertising, audience targeting, solutions for identity, application programming interface (API), custom, and programmatic, measurement and optimization. The company was founded by Jeffrey Terry Green and David Pickles in November 2009 and is headquartered in Ventura, CA.

Trade Desk Inc - Ordinary Shares - Class A

Trade Desk Inc

TTD is trending as it approaches new lows, sparking discussions about its future and potential S&P 500 exclusion. The community is debating factors like competition from Amazon, tax-loss harvesting, and the CEO's performance amid the stock's significant year-to-date decline. Some investors see a buying opportunity, while others express concerns about the company's ability to compete and innovate.

Adobe, Inc. is a global technology company, which engages in the provision of digital marketing and media solutions. It operates through the following segments: Digital Media, Digital Experience, and Publishing and Advertising. The Digital Media segment offers products and services that enable individuals, teams, businesses, and enterprises to create, publish, and promote content anywhere and accelerate productivity by transforming view, share, engage with and collaborate on documents and creative content. The Digital Experience segment focuses on integrated platform and set of products, services, and solutions that enable businesses to create, manage, execute, measure, monetize, and optimize customer experiences that span from analytics to commerce. The Publishing and Advertising segment includes legacy products and services that address diverse market opportunities, including eLearning solutions, technical document publishing, web conferencing, document and forms platform, web app development, high-end printing, and Adobe Advertising offerings. The company was founded by Charles M. Geschke and John E. Warnock in December 1982 and is headquartered in San Jose, CA.

Adobe Inc

Adobe ($ADBE) is trending as analysts debate whether strong Q4 earnings and AI integration are enough to offset concerns about 2026 guidance and competition from firms like Figma. The community is discussing recent price target adjustments and whether the stock is currently undervalued, presenting a buying opportunity, or if it's a value trap due to broader market sentiment.

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Should Vanguard Extended Market ETF (VXF) Be on Your Investing Radar?

Illustration showing chimeric antigen receptor (CAR) T cells (blue and green) being used to treat non-small cell lung cancer (NSCLC). | Representative image: Getty Images

Why Did Aethlon Medical Stock Tumble Over 12% Today?

Aethlon Medical's stock drew investor attention after the company announced a private placement and warrant inducement deal. 

Equity

Aethlon Medical's stock drew investor attention after the company announced a private placement and warrant inducement deal. 


Rising stock market chart on a trading board background.

Entero Therapeutics Stock Jumps After Company Rebrands As GridAI Technologies Corp.

The name change follows the company’s acquisition of GRID AI Corp in October.

<ul class="summary-bullets"><li>The company expects gross proceeds of about $60 million from the offering, which it intends to use for general corporate purposes.</li><li>Pasithea expects the offering to close on or about December 1.</li></ul><p>Pasithea Therapeutics Corp. (KTTA) on Friday announced the pricing of a public offering of 80 million shares of the company’s common stock at $0.75 per share.</p><p>KTTA shares traded 43% higher on Friday morning at the time of writing.</p><h2 class="st-heading-2">Offering Proceeds And Purpose</h2><p>The company <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/news-release/2025/11/28/3196323/0/en/Pasithea-Therapeutics-Announces-Pricing-of-60-Million-Public-Offering-of-Common-Stock.html">expects</a> gross proceeds of about $60 million from the offering, which it intends to use for general corporate purposes such as ongoing research and pre-clinical studies, clinical trials, the development of new biological and pharmaceutical technologies, and investing in or acquiring companies that are synergistic with or complementary to the company’s technologies, among others.</p><p>The offer price represents a 29% discount to the stock’s Wednesday closing price.</p><p>The company said that it expects the offering, led by investors including Vivo Capital, Janus Henderson Investors, Coastlands Capital, Columbia Threadneedle Investments, Adage Capital Partners, and Squadron Capital Management, to close on or about December 1. The offering will extend its cash runway through at least the first half of 2028, it added. &nbsp;</p><p>Earlier this month, the company was awarded a Hoffman ALS Clinical Trial Award grant worth about $1 million to study its lead drug candidate, PAS-004, in Amyotrophic lateral sclerosis (ALS) patients. ALS is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord, where patients eventually lose the ability to breathe.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around <a href="https://stocktwits.com/symbol/KTTA">KTTA stock</a> stayed within the ‘extremely bullish’ territory over the past 24 hours, while message volume stayed at ‘extremely high’ levels.</p><p>A Stocktwits user opined that the stock will erode its gains to hit $0.75 level.</p><p><stembedurl>https://stocktwits.com/GABBYGIRL/message/637652497</stembedurl></p><p>KTTA stock is down by 52% this year.&nbsp;</p><p>Also See: <a href="https://stocktwits.com/news-articles/markets/equity/china-byd-recalls-nearly-89000-evs/cL5aGIxRELP">China’s BYD Recalls Nearly 89,000 EVs – Regulator Cites Battery Output Concerns</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com</i></p>

Why Did KTTA Stock Soar A Whopping 43% Today?

The company announced the pricing of a public offering of 80 million shares of its common stock and said that the offering will extend its cash runway through at least the first half of 2028.

<ul class="summary-bullets"><li>The company has now proposed an early-stage clinical trial to evaluate the cell therapy.</li><li>Lunai is also advancing additional studies and expanding the clinical reach of its DCCT platform through collaborations with investigators in non-small cell lung cancer and prostate cancer.</li><li>The company is also preparing for formal licensing negotiations and pursuing activities ahead of the commencement of human clinical trials in early 2026.</li></ul><p>&nbsp;</p><p>Shares of Lunai Bioworks (LNAI) jumped 26% in the pre-market session on Tuesday after the company announced that it has secured its first letter of intent (LOI) to license its next-generation immune cell therapy.</p><p>"We are seeing accelerating validation from both researchers and industry partners," <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.prnewswire.com/news-releases/lunai-bioworks-secures-first-licensing-loi-following-landmark-breakthrough-showing-complete-tumor-regression-in-humanized-cancer-models-302624947.html">said</a> CEO David Weinstein. He added that the early licensing activity reflects growing confidence in the platform's potential to unlock scalable treatments.</p><h2 class="st-heading-2">Data For Cell Therapy</h2><p>The cell therapy, Dendritic Cell Combination Therapy (DCCT), achieved complete regression of both primary and metastatic pancreatic tumors with no recurrence in humanized preclinical models.</p><p>The company has now proposed an early-stage clinical trial to evaluate the cell therapy, manufactured from healthy donor cells and stored ready-to-use, across several high-risk tumors, including pancreatic cancer, which has a poor survival rate.</p><h2 class="st-heading-2">Plans Ahead</h2><p>Lunai is also advancing additional studies and expanding the clinical reach of its DCCT platform through collaborations with investigators in non-small cell lung cancer and prostate cancer.</p><p>Additionally, it is preparing for formal licensing negotiations and pursuing activities ahead of the commencement of human clinical trials in early 2026.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around LNAI jumped from ‘bearish’ to ‘bullish’ territory over the past 24 hours, while message volume rose from ‘low’ to ‘high’ levels.</p><p><a href="https://stocktwits.com/symbol/LNAI">LNAI stock</a> is down by 85% this year and by about 75% over the past 12 months.&nbsp;</p><p>Also See: <a href="https://stocktwits.com/news-articles/markets/equity/novo-nordisk-experimental-glp-1-drug-shows-weight-loss-blood-sugar-level-reduction-in-study/cL52hCvREXo">Novo Nordisk’s Experimental GLP-1 Drug Shows Weight Loss, Blood Sugar Levels Reduction In Study</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com</i></p>

 In this photo illustration, the Lunai Bioworks logo is seen displayed on a smartphone screen. (Photo Illustration by Thomas Fuller/SOPA Images/LightRocket via Getty Images)

LNAI Stock Soars Pre-Market After Immune Cell Therapy Gains Licensee Interest 

The cell therapy, Dendritic Cell Combination Therapy (DCCT), achieved complete regression of both primary and metastatic pancreatic tumors with no recurrence in humanized preclinical models.

<ul class="summary-bullets"><li>If the proposed bidding process is approved, interested parties can submit binding offers to acquire Clearside’s assets in whole or in part.</li><li>CEO George Lasezkay said that the company has “attractive assets,” including its SCS Injection Platform.&nbsp;</li><li>The company has also filed several motions to enable normal operations during the process, it said.&nbsp;<br>&nbsp;</li></ul><p>Clearside Biomedical, Inc. (CLSD) said on Monday that it has filed a voluntary petition for Chapter 11 bankruptcy protection in the U.S. Bankruptcy Court for the District of Delaware.</p><p>Shares of the company traded nearly 69% lower at the time of writing.</p><h2 class="st-heading-2">What Does The Company Intend?</h2><p>The biopharmaceutical company is <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/news-release/2025/11/24/3193383/0/en/Clearside-Biomedical-to-Pursue-Strategic-Sale-of-its-Business-Through-Voluntary-Chapter-11-Process.html">seeking</a> authorization to pursue an auction and sale process. If the proposed bidding process is approved, interested parties can submit binding offers to acquire Clearside’s assets in whole or in part.</p><p>"Our Board of Directors and management team have thoroughly assessed all of our strategic options and believe that this Chapter 11 structured process represents the best possible option for Clearside and its stakeholders,” said CEO George Lasezkay.</p><p>Lasezkay also added that the company has “attractive assets,” including its SCS Injection Platform, which is a proven in-office, repeatable, non-surgical procedure for the targeted delivery of a wide variety of therapies to the macula, retina, or choroid to potentially preserve and improve vision in patients with sight-threatening eye diseases.</p><p>The company’s CLS-AX clinical development program is also up for sale. CLS-AX is being developed for the treatment of serious back-of-the-eye diseases, including neovascular age-related macular degeneration (wet AMD) and diabetic retinopathy.</p><p>The company has also filed several motions to enable normal operations during the process, it said.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around CLSD jumped from ‘bearish’ to ‘bullish’ territory over the past 24 hours while message volume stayed at ‘high’ levels.</p><figure class="image"><img style="aspect-ratio:587/60;" src="data:image/png;base64,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" width="587" height="60" alt="CLSD’s Sentiment Meter and Message Volume as of 11:21 a.m. ET on Nov. 24, 2025 | Source: Stocktwits"><figcaption>CLSD’s Sentiment Meter and Message Volume as of 11:21 a.m. ET on Nov. 24, 2025 | Source: Stocktwits</figcaption></figure><p><a href="https://stocktwits.com/symbol/CLSD">CLSD stock</a> is down by 94% this year and by about 95% over the past 12 months.&nbsp;</p><p>Also See: <a href="https://stocktwits.com/news-articles/markets/equity/oscar-health-stock-soars-on-reports-of-two-year-obamacare-subsidy-extension/cL5bB5mREQ7">Oscar Health Stock Soars On Reports Of Two-Year Obamacare Subsidy Extension</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com</i></p>

 In this photo illustration, the Clearside Biomedical logo is displayed on the screen of a tablet. (Photo Illustration by Sheldon Cooper/SOPA Images/LightRocket via Getty Images)

CLSD Stock Plummets After Company Files For Bankruptcy Protection

The biopharmaceutical company is seeking authorization to pursue an auction and sale process.

In this photo illustration, the Tempest Therapeutics logo is seen displayed on a smartphone screen. (Photo Illustration by Thomas Fuller/SOPA Images/LightRocket via Getty Images)

TPST Stock Plummets After Inking Deal To Acquire CAR-T Programs From Privately-Held Firm In All-Stock Transaction

The transaction is expected to close in early 2026, provided it receives all required approvals. 

<ul class="summary-bullets"><li>The January meeting is intended to discuss the clinical trial design, patient population, and a potential approval route for Buntanetap in PDD.&nbsp;</li><li>According to Annovis, PDD affects approximately 30% of Parkinson’s patients.&nbsp;</li><li>The company also said that its late-stage Alzheimer’s Disease study is ongoing with full regulatory alignment.</li></ul><p>Annovis Bio, Inc. (ANVS) on Tuesday said the U.S. Food and Drug Administration (FDA) has scheduled a January 2026 meeting to discuss the company's pathway to developing Buntanetap for the treatment of Parkinson's disease dementia.</p><p>Parkinson's disease dementia (PDD) is a type of dementia that occurs in people who already have Parkinson's disease, characterized by cognitive decline, such as memory problems and slowed thinking, along with the movement issues of PD. According to Annovis, PDD affects approximately 30% of Parkinson’s patients.</p><h2 class="st-heading-2">What Will Be Discussed At The Meeting?</h2><p>The meeting in January is aimed at discussing the clinical trial design, patient population, and a potential approval route for Buntanetap in PDD, the company said. According to Annovis executive Cheng Fang, PDD is a natural extension of the company’s Alzheimer's and Parkinson's programs, wherein the company generated data demonstrating meaningful cognitive improvement with Buntanetap.</p><p>"The scheduled January meeting marks a key milestone for our pipeline, underscoring buntanetap's potential across multiple neurodegenerative indications and the strength of our scientific approach."<br>Maria Maccecchini, CEO, Annovis</p><h2 class="st-heading-2">Alzheimer’s Trial Progress</h2><p>The Malvern, Pennsylvania-headquartered company also said that its late-stage Alzheimer’s Disease study is ongoing with full regulatory alignment on study design, endpoints, and patient population.</p><p>The study is set to support applications for the drug in symptomatic treatment and disease-modifying treatment with Buntanetap.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p><a href="https://stocktwits.com/symbol/ANVS">ANVS shares</a> traded 16% higher at the time of writing. On Stocktwits, retail sentiment around ANVS remained in the ‘extremely bullish’ territory, while message volume remained at ‘extremely high’ levels.</p><figure class="image"><img style="aspect-ratio:624/61;" src="data:image/png;base64,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" width="624" height="61" alt="ANVS's Sentiment Meter and Message Volume as of 12:06 p.m. ET on Nov. 18, 2025 | Source: Stocktwits"><figcaption>ANVS's Sentiment Meter and Message Volume as of 12:06 p.m. ET on Nov. 18, 2025 | Source: Stocktwits</figcaption></figure><p>ANVS stock fell 31% this year and by 49% over the past 12 months.&nbsp;</p><p>Also See: <a href="https://stocktwits.com/news-articles/markets/equity/waymo-announces-robotaxi-launch-in-five-more-cities/cLPV4fyRE7M">Waymo Announces Robotaxi Launch In Five More Cities</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com</i></p>

Global stock market chart and trading board - stock photo

Annovis Stock Rises After Company Confirms Meeting With Regulators To Discuss Drug In Treating Parkinson's Disease Dementia

The meeting with the FDA is scheduled for January 2026. 

<ul class="summary-bullets"><li>The strategic review comes after Neuphoria discontinued advancing its lead drug candidate called BNC210 for the treatment of social anxiety disorder in October.</li><li>Strategic alternatives under consideration may include, but are not limited to, mergers, acquisitions, partnerships, joint ventures, licensing arrangements, or other strategic transactions, the company said.</li><li>The company said it will carefully evaluate and consider Lynx1 Master Fund’s indication of interest in connection with its review of strategic alternatives.</li></ul><p><br>Neuphoria Therapeutics Inc. (NEUP) initiated a review of strategic alternatives, including potential acquisitions, on Tuesday to advance its pipeline programs and maximize shareholder value.</p><p>NEUP shares traded 4% higher in the pre-market session at the time of writing.</p><h2 class="st-heading-2">Strategic Alternatives Under Consideration</h2><p>Strategic alternatives under consideration may include, but are not limited to, mergers, acquisitions, partnerships, joint ventures, licensing arrangements, or other strategic transactions, the company <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://ir.neuphoriatx.com/news-releases/news-release-details/neuphoria-announces-initiation-strategic-review-maximize">said.</a></p><p>The company added that it does not have a defined timeline for exploring strategic alternatives. Further, it is not confirmed that the process will result in a transaction.</p><p>The strategic review comes after Neuphoria discontinued advancing its lead drug candidate called BNC210 for the treatment of social anxiety disorder in October after a late-stage trial missed its primary and secondary endpoints. Neuphoria then also said it will assess new development paths for BNC210 as a treatment for post-traumatic stress disorder (PTSD).</p><h2 class="st-heading-2">Lynx1 Master Fund Expresses Interest</h2><p>Neuphoria on Tuesday also added that it received an unsolicited non-binding indication of interest from Lynx1 Master Fund LP earlier this week to acquire all of the outstanding shares of Neuphoria that it does not already own for $5.20 per share in cash. The company said it will carefully evaluate and consider this indication of interest in connection with its review of strategic alternatives.</p><p>Lynx1 Master Fund LP also expressed intent to nominate certain individuals to stand for election to Neuphoria’s Board of Directors at the company’s 2025 Annual Meeting of Stockholders, the company said. Neuphoria’s Board of Directors will now review the proposed director nominees. The annual meeting is scheduled for December 12.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around <a href="https://stocktwits.com/symbol/NEUP">NEUP stock</a> jumped from ‘bearish’ to ‘neutral’ territory over the past 24 hours, while message volume stayed at ‘low’ levels.</p><figure class="image"><img style="aspect-ratio:623/62;" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAm8AAAA+CAYAAAB9e/zzAAAQAElEQVR4AeydC1QUV57/vwWNzUtoQJA2EsXngI+Ij1llNsmEjPn/xWWOUScPOWvOiLJKzJxNNLOPuMmcjNmZnTUmOyrxxEdWZ3CSidHseoI5cYLrcUTNBNBoAF8LRmJ3QGnk3dJ07/1V02130/SLpmnk16equure3/3dW58uvvzuvVXdISZ+MQEmwASYABNgAkyACQwZAiHgFxNgAkyACTABnwhwISbABAaDAAdvg0Gd62QCTIAJMAEmwASYgI8EOHjzERwXCy4C3BomwASYABNgAsOFAAdvw+WT5vNkAkyACTABJsAEnBEYcmkug7e7d7vQ1NSC+vpG3LzZwCsz4GuAr4FBuQZIg0iLSJP8rbLkk3xTHaxzrPN8DfA1MFjXAGkQaRFpkjud6zN4Iwc6XTMUCgXi4mKgVo/CmDGJvDIDvgb4GgjoNUDaQxpEWkSaRNrkTtg8zSdf5JN8Ux1U16DqHF9bAb22+LPm/+nBcg2Q9pAGkRaRJpE2udKxEGeZt2/fkZOTkuIRHR2BsDAFJEmS03jDBJgAEwgkAUmSZA0iLSJNorotGkX7vq4WH+STfLPO+UqSyzEBJtBfApLknc71Ct4o2gsNDYFKNZIDtv5+GkO3PLecCQQlAUmSZG0ijSKt8rWRVJZ8sM75SpDLMQEmMFAEJMm9ztkFbzTPqtffRWxs9EC1if0yASbABPpNgDSKtIo0y1tnVIbKkg9vy7I9E2ACnhBgG38QII0irSLNcvRnF7y1t3ciKiqSR9wcKfExE2ACQUVAkiRZq0izvG0YlWGd85Ya2zMBJhBoApLUt87ZBW8U3SmVYYFuH9fHBJgAE/CaAGkVaZargs7yqAyVdZbHaUyACTCBYCJAWkWa5dgmu+DNYOiGQhHqaMPHTIAJMIGgI0BaRZrlbcOoDJX1thzbMwEmwAQCTYC0ijTLsV674I0yJYmfKiUO/l3ZGxNgAv4mIEm+a5Uk+V7W3+fB/pgAE2ACfRGQJOda1St468sBpzMBJsAEmAATYAKDQICrZAIOBDh4cwDCh0yACTABJsAEmAATCGYCwR28NWuhaQ5mfNw2JjCsCPDJ3tcE6lB6+Axu3NfnyCfHBO4PAv0P3oxalL6/C9u20foO9h6+gEajj3AazqDok8vWwldPHsbBk9esxwO1U/3JByhtGCjv7JcJMIGhTqD+1Aco3PUZqm217foJ7N0ZnNphOH8EhUcq7bDfOXsQ+45r7dLsD3S4WatFo30iHzEBJhCEBPodvGn+5zNcVD2BF15YI9Z8LEyPhNJXr406NHborZgmLV6HFxZPtB5bd/y604zG23p0GvzqlJ0xgSFDwGQy4fbtRnz7rQZXr9aisvISzp//GmVlX+Hs2XJ88UUFyssv4KuvKlFVdQU1Nd9Ao/kOLS2tQ+Yc+9vQbr0eClMdLl6456n6q+voRHBqh2KKGrG111FtbW4zvr6kQ1JqsjWFd5jAcCIgZA4dIr5oaWmHTteCW7eaUF/fCK32ttCzBrHewnff3UZDg07o4R3cudOK1tYOOPuajmDg5muYZW175917wRYQipSpExHVk9t29QTe37ULhYW7sFeMqLVROo2uHfkSFz/Zj8Lt2/EW9WY7RAalH7sGw7d/RmFPb5Z6u0WnzENitH/k1AV8/J4Y4fuPXSgqrcONkwext1D42HkE52Xnwo9Rh/OHhe+dot53D6L0W5EmFhpdKzl3Sm7PNrm8uQdK6WW6Znx9WNiLNgpTXpjAfU+gq8uA5uY2WahInCggu3HjphC02yK9VYhcJ7q6umASimc0GoWA3UV7e4cQtGYhcA24fr1OfqffB9WJvx8SRbK9n8EpYmLQeOWC+RSNl1FdH4OkSPOhvG27hpL39wr9Elqy5yiqezRJc+og3hUaWLhzL94/WQfqJzpLazx3FPtIL7e/g237T0BjGeX79oysW4WkafL6gXmmoI/65LZETEFqbB1qauUjoOMyau6MRep4cWzRSGpT4X4cqWoXiQ4L6fHvz6C+J5n0t8hPWtzjclDfuPLhQcB07X/RvXsvutashamiQuhXi+h0tsn6RrpHX8FB+iZkTta67m6j0D0D6FcN2to6ZC2k92DUuX4Hb6kPPwr1N0dEEPYxSi40yMIkXxaNZ3DwMx3SVqxBQcEqfP/uCZRcEjkGPfS1l9A4MxcF69djUdI1nC1vBhLnI/fhscADf42CtU8jMxGg3q5e3y0Kmfdrr+vxyHNihO9v02E4ewRnRz6BVQXrkZOiRdkX5iCv+pODKIt9QvgQ9T6pxpXPz+CO8KDvaED19TgsyuspX1Yh90q/tzgH06JjMO1JYb94irDkhQncvwRIrBobm+WgrbW1vUeouhAbG+P1SceIYIZEjgI3CuCoF9smBI+E0GtnQ6FA0kSk6i6hjDqbl4SGPTAW8V2WhutQ+lEJGtOekbUnf74BJSV0C0glzn4J/NVaoS9rV2H5/LFQwFkaoFRnYInQp4L167AwthKfnRa6iAaUfFqJhCeo/Bo8kaJEyo+eFvrYV32W9sRg2sRI3LhcJyfoL1xD4/iJ+J44qv7kfZQJ7SwoED6fy0Db54dR6jhXSjotRhvN6mvWX39psWgCL0xgQAmYxKizYdNr6MrLR/fvD8B05SpMX5ZBqRzhdb0jRoyQg7lg07kQr8/EsUDUFOTkr8NzjySi8cwH2NYzkqa/eh3NQtwNlypQVv4V9COUaPjWPNqFyLGYnBIKesWOjBJBmpOeH2U6rFHJQiypxfExiIIak2fFyBZREUrARDJzHTXfhiI+XCPqFPXeMEDZqkUtzK+k8emItZQncTIn85YJDBKBwFXb3d0tpgqa5WmCzk7b0XLIwuRL8BYVFWF3AtRrpakGCuJI6Owy74sDNaZPbMeVr9tRfVmHlDTR2bScV8c1MbIVg9huEdyVV+B8hwLh9RpoMB6pD+hw9uAJXNTooQiDeDlLA6JGJ6K7tgIlnxzBuVsUMJEukq4poRwpioklNFSP5kbx+fVZnzDqWWLTxkN545poA1D9TSPGT6HOKWlkFMY/lGy2ipqBWeOaUXNV+DSneLTtrxZ7VAkbMQEvCZi0Whg2/yu6froaxj+fsittLCv3KXgLoZjBxlOw6JxDs2xa6NWuCJim/gDL16xCZtRllF3Qo1NMy9i5UM/A96fG2SX5/0APQ5et1xhMnp+BFNsk3mcCw4xAS0ubmOJsFFMFzv9B0xTqyJHRXlGJiAiHwWB0WsYSKNI9JTTS59RoiCaqZ02E/vJnuHhnHKaPszkJveHerAMlhyTjoflTEY9IPLRcjLjNjULNZ/tReLgSeqdpYiTt93tx9KoSkx9+Ao+mRpEXsSbjrzKUOP/RB/j48Ac4Xj8FWXOVIuLuqz5RxLLETxTaV4eaxgu4oh2PyVMpgzQyFOFhtH9vNXQ5vzbuWXi7R/XYlmEttqXB+34mIDqn3XveQ1fuczD+qQRiDrRXBaYrV6DstgsQetk4JtCvG9y9a3BMlo8HW+fk4E1uiU+bdlSf/BI3HHgolUrEjlVD2W5A/KwMzJktVvE+/QEl3L6c/z9wW8xsMA5jEtvRpphqrlOud5wQUHNu31sDxFR339mcwwSGIAEKnOjmW7pB113zJUnyqldKI3U0ZerKL91TQvXTVKoruyGVF5+O1K46tKXOhNq24aqxGKNsgyFeaB3pDq1pyVCiW3QoQxE/YS5ynpuPpG+u4YrTtDrc1CVjzhPpSIlRoq3DEkw143xlN+YsW4LHHl+CVSsfhTpEVNxnfSLPuiQjLbUbNSXXUJ9injIFxgmN1KHmcrvZyihG4jRKjBlrnsUwJ4rtaBF2tupQL+txO+pvtYlEbxaqxxct9qYOtmUCIk67UYeuvytA9++KxHA1jVT3QcVognTuPEJD6Q+oDxuHZKWYZg1WnfP8LBxOynwYiaSRGhzd+Y75Jt3t+1A24gfIekjkjstCzjQdjhbuR5HoMcqP1N8W6a6WKVOQWn8C23aKHuglV4Z95SkxJ+cJxJzfh8L9H+Pg/r1495PLsMig81JC4CYocPHQLhS+f4Yfk3cOiVOHGAEKnG7d0sn3tHnSdL2+y6v73uh+NwoO3fmmhxhoKrWpqcWd6RDJj8Mjz6zE8vlxDu0di4WL09H46TvYe+AIivbsQtEZHdBQgYPv7cW+g5R2Bm0z52G6szSMRWqiFsf2fICifUWo6ojs8R+DlKQ2nD0gdFSshe99gCMnr6FN2DutD/Yv9cSxaLuhwRihreYcW40swt7Cz9A4LRsL5VHEOMRG1aHspBYImYLpD2pQQg817DyM+qh4c3HnWyeptvV4qsVO3HASE3BBwHThIrrWPg/TVc++UszbqdOwsDAxw+AiIOxp22DoXD+DN4iRtRzkv7AOeSuexnN/tw4FyzOsI13qHzyNgoKn8TfUYxTvmQniTNWPYlWe6D2KXVrUWSuxKqvn/ouIdCxZvw75P12FRWKI3zbPdh+YgeUvLgHFiL180D14a4SPZVlY9Owq5OdMEb1fiKmL9VhuKeBY/rGVeDF/JfKfmW9tO/nllQkMRQJ0vxlNWRpFT9PT9uv1dz0O3iRJ8mqUjtrQ3t4pP35PIkfHQ2210x9lDKLkacdkZOWtRJZlCO6B+chduw65f/Molv90DXIzRYCXOBfP5K9C7qJHsWTlGjz3WDLgLA1xmPPMGuT/ZBGW/20ucpbnmnXReBnnvh2LJfRwwVqR/9R8hF8+hbMaQdBZfSLZbhGd6PwX12FJmk2qVSNzkCv85v5AtEnOFgHo6nVYKR8rMf1Joecrn0Zefq4ITJ82t0fY2bFw1FJbPbfWk2WnxcIFL0yg3wSMxz5H199vANo8HxU2eXnfm8kkDz173NZA6lyIx61yY6iMsQiag2GIErFiGgAev0LFPwb0+6WI6qM9fXkWU72KvvI4fWgQ4FYKHesAPfnpLQq6CTc2diTGj38QkydPwLRpUzFr1nR8//sZmDdvFh56aBrS06dg0qRUTJgwDnS/h7d1UIBIj9yb7tvHUc1ESAuVDsrqTI+cpfUqq28TU6jtaGzqlp13N2tQ3x2HJJV8KG96lZFT3W+ofsd2IiQUCpu2++rbtnaqxxzs2qbyPhPwnYDx4/+G4Y1fQQiRV05MjY0IN3YjNjYacXExGDVKhaSkeKjVo+SV9imN8lSqkcK9+e/Om0oCpXM2f6beNI9tmQATCDYC1OujKUpv2hUZGS4LGImXQqFAcnIiEhLiMHJkNMLDlQgJCUFoaCjoAYWYmJHCNh6JiQmIiYkW73GIjo4U+SEeV0nTuRTAeVxguBtGZGD5snGoP1GMjw8fwdHzCjFtm4PpEcMdDJ//cCVgLP4Uhrd/6/npC/0K+X8LEbbtbYw48l+QoiJBT8pHRCgxYkQY6KEESZIgSRJon9Ioj7QxmHXOc9X1HBVbMgEmEGACdP+ZN4Eb3Yg7enQ8qHdJYuVLc8PCFCKIi8Lo0eZgjsQPNY+R/QAAEABJREFUHrwogKMvCPbAlE0EAcXoDCx6MgdLaP3/c5ESIxJ5YQLDkICJvr/Ni8AtZN5chBXtg+Kf/gHSjOlAiOQ1tWDVOQ7evP4ouQATCC4CNA3Z2HgH9O6uZTSSFhc3UoyuxYoRs1B35h7nR0dHiOmHOFBQ6Ekh+oJgml7wxHb42fAZMwEm0IvA3bsw/MtrgHjvleeYEBMDxSv/CMW//xpScrJjrs/HwaRzIT6fBRdkAkwgKAjQiBuNvLlrjEIRKk910hSoO1tf8ml6NSEhVp6S8KS8TtcCutfOE1u2YQJMYHgTMPzHdphu1LmFII0fh7C97yJk4Y/c2vpiECw6x8GbL5/eMCnDpxn8BIxGIzo777ptKE2NJibGidG2gf+Tp5uB6Z4Sd42itnd0dLoz43wmwASGOQF60MB48s9uKUgPzURY4TZIo0a5te2vwWDr3MAreX8JcXkmwAT6JEC/jjB6dLzL0S4K3GhEzNN70vqszIsMd8JGD0ckJKhANwZ7MmroRdVsygSYQHAQ8Fsr7kZFY8T7v0fo8mVAiPOwRZo5A2Fb/g2IjPRbve4cDabOOafgrsWczwSYwKAToMCNntyk73SjIIgec6dAzbZhoaEhiI+PlZ+ksk0PxD4Jm+M9cCEhkvyYfmKiSv5N1fp6HfjhhUB8GlwHExiaBCw619CmR3f+aoTtfw80wmZ7NtKoBIRtfh0IC7NNDsj+YOlcSL/PrrMJWq0WTa22njrR1CvNNj/A+7U7sDhFjcXv1AS4Yq6OCQwcAcvPXpG4UQBHv2EaFxcjgrUYMT1qfhiBjilgGrhWuPYcHx8jP4pPVjSVmpSUIAeS9fWNoIcW6CGLzk69R99iTj58Wv1RyKJznf5wxj6YABPwlICjzjVFjUTI1i1QvPE6pDFqCEGB4hevAjEjMVivwdC5/gdvx56HWq1G3I/3QGslV4LnRVqmX4KlYuRKEnKPWJ17v2PoRE2dFjV2Aab3brgEEwgWAjTVSEGPbXs6OvSgoKirqxs0spWQECt/j5GtTaD3JUkSwWSs/CQqjQ7evt2EpqbeDypQIBfotnlVX4/OPX/Mq1JszASYQD8IuNK5tpmzoPjPPVD85leQpk/rRy39LypJgde5/gdvlvM+vh4bjgxAt1SrsQkKLZX5//0Xv/gFnnrqKf87vueR95iA3wjQF/I6c0YjWTQC19Cg8zlwq6urQ1paGqKiolBWViZX09raih/+8IeikytZVzqmdNnAxYaecqWHKmh0sKvL4NSSAk9qu9PMYZrImjRMP3g+bSsBdzpXr2uBNHeO1d6TnRMnTsj6JklmLXv22WfR2NhoLXr06FHR2UySdW7SpEk4d+6cNc/VTqB1zk/BWzayczpx4GebUeFcm9F5cQeWpZhhSWHp2Hi8ycyhZ0pzo7VHW4KNYopT/VIJQHkZ6yH2cGClGuqUxdhRK4pResrj2HGmGKtln7korj2EjVkTENHzgURkbERJTxXw4EVCmZ6ezgGcB6zYZPAJ9CVqlpaRkEiSZDn0+J0CqC1btuDGjRtQKpXWcm1tbXLaihUr8OGHH8or/c2Eh4dbbVzt0BddusqneinAc2UTtHmGJhS/NNtOe4pvmVtb9Vam0K3VONQz6l/8M9IxoV1Xzfk17yyW84ud9HuJL2uSmRNvicDwW/2tc6QzX3zxBbKyslBbW4udO3fij3/8I377W/MvNtTU1GDNmjXIycnB5cuX8eCDD2Lt2rW4c+eOR/ADqXN+Ct5qkPnsK0itfQMb37s3eWo926YDWDZjPUrStuDzmv/F5y+H482sZdhDpj1TmhqreHVCI6Y4tbdEwqgsbPjnpaCv2FuwZgd2bN2ArFHCq1ymBOsX5KHyJ9vx0WebkKUtR6lqBfaUlKN87wqoz72Jxa+eFsaeLyyWnrNiy8EjQL9QQF+z4aoF0dFRrrL7zPvTn/6Effv2YfXq1dDr9VY7qs9gMGDmzJlYvny5vNLIGz01ajVysaNUjoA7YesYol8bUvHqbCx+qwbZv/kc5X/ZjuxaoT3zNskd2bR5s9FUtwfFJwlOBUo/1EJbV4JDx0n8OnH6aDG0kxdgdjjl915Zk3oz4ZThQWAgdE6SJLz88svYsWMHxo0bhx//+McYO3YsKGgjqqWlpdDpdCgoKMDkyZPx85//HBcuXJBXyne3BlLn/BS8AeHzNmJzDlDysw0o7ullWk605r0tKEYGNv5rLtLDI5Be8DyyxXhayV8sFn28R6cha9FsxIns1IeXYulPspAWLQ56lvB1RSjd+jyWLkxD+PzNKD20GUsz1Agfn4kFyUDn6VLU9Nh6+sZi6SkpthssAu5GqOgJU6XS+6eubt++jVdeeQXPPPMMHnnkEbvTox+ip7WyshL5+fn45S9/iVu3btnZuDug3wp0ZaPXd7nKDtK8Yuz4lVCZnB0oejkLGXOfR1FhNiA6sjtoNmF+FpaKlpeeqxJpJSjWZiFrodDJ46UiVQRzwiZ5/my5gyoSnC6sSU6xcOJ9TmCgdI6wdXZ24sqVK3jttdfw3XffyZ1RSr9+/TpGjRqFMWPG0CESExPl9/r6evndk02gdM5vwRugwoqtW5DWeQAb3xFChXuvqooKcVCBTfPUoIcb1CmrRTAnkvq5pKam3vNQdwir0yRExKmRuXIzDpk7tvfyeY8J3CcE+rpvzHJ67sTDYmf7TtMJ7777LlpaWuQALszhkXsahSNBi42NlacSaGqVRt68ETV3v+xAbTAYujGkXk0auYOY9vAChPc0PHye6GSK/dKLIqhTZCLrMaDqmOhIni5BRfICbBCdUBwuwemrpSjpDMey7AzwiwkwAXsCA6FzlhqOHTuGKVOmYPfu3XjxxRfxox+Zf43h0qVLFhO7dwr07BJcHARK5/wYvImzmbQBe15QoerVj1DzPXHcs6TNSBN7C7D9hgkk0Ja1SIzUiQx5aWoV06TynqcbWzst9qxchj2dz+PzBhN0N0qxebptvuf71Mul0QWaB/e8FFsygcAR6OpyPUJFQ/fetqa8vBybN2+WH1J4/fXXsW3bNnR0dMhpdMPuxIkTQfeK0L0hmzZtQmFhIb7++mvrAw2e1EdfWRIWpnBp6u7cXBYejEyVGqmiXnMHVezQUlUO6r5mTqecZDF7IPTv+GnsuVAOPDYb2RkLkNxZitLD5cJuKbLmU6G+V9akvtlwzv1LwJ0W+KJzFlp0T5vBYMDZs2dx4MABvPTSS6DjqVOnWkzs3mkK1S7BxUGgdM6/wZs4oQWv70B252mcrhYHPUvqk3nIwGlsWvUmSmq10GqrUHy4AnK4Fq2CWtiV/KEIVSJ9z1N5OCCOrYvQeurRHvrDAdRom9BpsObY7HSgqUUcRqsRZ9Ci5vgeFF0Ux46Lrq/yZkMWSTMH3gYvAfotUKPR5LKB7gIkZ4XpPo+EhATQSNqnn36KL7/8Uu5onTp1Sp4epSlT6nRZykZERMi7JHjyjocbd23r6grukbeak4dw6EPLWgEtspEnOqz4w2ZsOl4DbW0JNr0uFEyVh6UPm6GkPkb37X6EHe9okTFPjLLNEqNxqMCevRUimMtCptA4s2XvLWtSbyZ+S2FHQUtgoHSOTtiiWaGhoZg3bx5oBqG4uBgNDQ2g++DodpCbN2+SqXz/G+0kJSXRm8drIHTO78EbVCuw/Teip2l7mmJErqRkA9THN+LxVDXU6nQs/uePUEHRW3IuNqxJRueR1UgX6W+O3YxX5toUHp+HzT8V+X/IxQR1KjZ9aZNn3U1F3qt5SL64CbPVakwo0CIzJ9yai0lLkSd8Vv0qF2/2POV1L9O8N378ePCIm5kFb4OXgNFodNk4hSIUkuT9U6Y0bfDNN9/AstJDC5GRkTh69Cgef/xxbN26FevWrZPvE6mqqsLbb7+NBx54ANOnezfE7U7U3J2fy5MPQObpf1+GZU9Z1lwUCT1ZsLUUuxdp8EbWBKhTH8cbddnYfXo3sqN7GjQ3E4vRhKamcGTOSwUUs81TqdVVSFuUhWQ4f7EmOefCqfc/AXc64KvO0VOjy5Ytw69//WvQVyKRvtEUalpaGlQqFTIzMxEXFyfPLJAWvvXWW5gxY4a8ekM9EDoX4k2DnNrmFIkeeiU2TLqXm/pypUgzofLlVGui6rEtqOzqgE6jgUbXAVPVZiwIp+xwZL+rQYdOA12LCZVb87D5LyaY9mdTplhVyN5ryddhC00xiGCw0iRsbf3n7IamQwdNA/neje3/Ld4vbECq8ACx3fCXDlF3KTbYTOfKWT2b2tpa+ZHhnkN+YwKBIuBVPe5ELSSk/3/Sjg2SJAnUOz1x4oR8nwh9fUV1dTV27doFu/tOHQs6OQ4Ndd0+d+fnxGVgkmSdM8m6RiOQ5rXSrHuKNOQVa2Bq6dEfzSfIs9MZEcwJvTKZOrD9r6m5ycgrMfuy1UjKsV1Zk2xp8P5wIuBOB0J81Lno6GgsXLgQdGtISkoKsrOz5QcUKEij2QTSM7o15He/+508Cke3imzfvh10r683/AOhc66V1JvWemQbDlVyMpJVctQG21e4KhmqaNsU+313+bJ1uArJo8Ll3d6bcKiSVegrF/xiAkOAgNHNlGlIiOSXs8jJyQF9t9ucOXNkfzS9QCNuNL1KT2dpRCds0aJFcp43G3eia3QzsuhNXQG3jXalPwFvDVfIBIYsAeMA6VyomCpdv369/GAW6Rjp2VdffSV/aa8F1tKlS2Xto2lU+unPuXPFtJ0l08P3QOjcveDNw0axGRNgAoNHgH5iasyYRPS1xsfHDmjjVCqV/O3jJIK+VDRiRFifbadzGjUqzhe3XIYJMIH7iMBA6xzpF93HRnrmDFtYWJg8Ikd2zvLdpQVC5zh4c/cpcD4TYAJMgAm4JcAGTIAJBI4AB2+BY801MQEmwASYABNgAkyg3wQ4eOs3QnYQXAS4NUyACTABJsAE7m8CHLzd358vnx0TYAJMgAkwASbgKYEhYtcreKNH4IdI27mZTIAJDGMC/dGq/pQdxsj51JkAEwgwgb60yi54oy++Mwy13xYMMEiujgkwgeAgQFpFmuVta6gMlfW2XIDtuTomwASYAEirSLMcUdgFb/R4q17v+ncTHR3wMRNgAkxgMAiQVpFmeVs3laGy3pZjeybABJhAoAmQVpFmOdZrF7xFRoajra1d/hZxR0M+HqYE+LSZQBASoKkE0irSLG+bR2WoLPnwtizbMwEmwAQCRYA0irSKNMuxTrvgjaI7pXIE7txpdbTjYybABJhA0BAgjSKtIs3ytlFUhsqSD2/Lsj0TYALeEWBr3wmQRpFWkWY5erEL3ihTpRqJ7m4jmppaeASOgPDKBJhA0BCgnihpE2kUaZWvDaOy5IN8kU9f/XA5JsAEmIC/CZAmkTaRRpFWOfPfK3gjo4SEWHpDfX0jWls70NVl4EBOJsIbJsAEAk2AhIw0iLSINInqt2gU7Xu29ray+CCf5JvqoLp6W3IKExzQm3wAAADdSURBVGACTGBgCZD2kAaRFpEmUW0WjaJ9x9Vp8EZGFO3FxcXAYDBAp2uGRnMLN2828MoM+BrgayCg1wBpD2kQaRFpEmkTaZQ/VvJFPsk31UF1sc6xzvM1wNdAoK8B0h7SINIi0iTSJlca12fwRoVonpUcJCXFu/wxafpBaV4TPWLEnJgTXwPeXwOkQaRFpEmkTf5cySf5pjr4s/H+s2FmzIyvAf9cA6RBpEWkSe40zmXw5q4w5zMBJsAEmAATYAIBI8AVMQGZAAdvMgbeMAEmwASYABNgAkxgaBD4PwAAAP//MmvGbgAAAAZJREFUAwARnUjda84bUwAAAABJRU5ErkJggg==" width="623" height="62" alt="NEUP's Sentiment Meter and Message Volume as of 8:28 a.m. ET on Nov. 11, 2025 | Source: Stocktwits"><figcaption>NEUP's Sentiment Meter and Message Volume as of 8:28 a.m. ET on Nov. 11, 2025 | Source: Stocktwits</figcaption></figure><p>NEUP stock is up by 43% this year and by 11% over the past 12 months.&nbsp;</p><p>Also See: <a href="https://stocktwits.com/news-articles/markets/equity/poet-technologies-and-quantum-computing-team-up-to-boost-ai-data-speeds/cLPdoHVREPl">POET Technologies And Quantum Computing Team Up To Boost AI Data Speeds</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com</i></p>

NEUP Shares Rise Pre-Market As It Explores Strategic Alternatives, Including Potential Acquisition

Neuphoria also added that it received an unsolicited non-binding indication of interest from Lynx1 Master Fund LP earlier this week to acquire all of the outstanding shares of Neuphoria that it does not already own for $5.20 per share in cash. 

<p>Shares of Caribou Biosciences, Inc. (CRBU) jumped 52% in the pre-market session on Monday after the company announced positive data from early-stage trials of two of its CAR-T cell therapies.</p><p>While one of the therapies was evaluated for the treatment of multiple myeloma, a blood cancer of plasma cells, the other was assessed in B-cell non-Hodgkin lymphoma (NHL), a cancer that originates in B lymphocytes, a type of white blood cell that fights infection.</p><h2 class="st-heading-2">Study In Multiple Myeloma</h2><p>The company said that the first clinical data for its CB-011 <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/news-release/2025/11/03/3179047/0/en/Caribou-Biosciences-Announces-Positive-Data-from-CaMMouflage-Phase-1-Trial-of-CB-011-in-Multiple-Myeloma.html">highlights</a> its potential as a best-in-class allogeneic CAR-T cell therapy for relapsed or refractory multiple myeloma.</p><p>The company now expects to advance the program into the dose expansion phase by the end of the year. In the dose escalation portion of the trial, CB-011 had a manageable safety profile across all dose levels, the company noted. The portion of the trial evaluated the safety and efficacy of CB-011 in 48 patients at multiple dose levels and following two different chemotherapy treatments.</p><h2 class="st-heading-2">Study In B-cell non-Hodgkin lymphoma</h2><p>Meanwhile, data from an early-stage trial of vispacabtagene regedleucel (Vispa-cel) demonstrated the efficacy and durability of the cell therapy in patients with relapsed or refractory B-cell non-Hodgkin lymphoma, the company <a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://www.globenewswire.com/news-release/2025/11/03/3179104/0/en/Caribou-Biosciences-Announces-Positive-Data-from-ANTLER-Phase-1-Trial-Demonstrating-Efficacy-and-Durability-of-Vispa-cel-CB-010-an-Allogeneic-CAR-T-Cell-Therapy-on-Par-with-Autolog.html">said</a>. Vispa-cel was generally well-tolerated, allowing for administration in the outpatient setting, the company added.</p><p>“We believe that with these results, Caribou has achieved what the field has long sought — strong evidence that an allogeneic CAR-T cell therapy can be on par with the efficacy and durability of autologous treatments and broaden access with a safety profile that allows for outpatient use,” said CEO Rachel Haurwitz.</p><p>Allogeneic CAR-T cell therapy is a type of "off-the-shelf" cancer treatment that uses T-cells from a healthy donor, rather than the patient's own cells, allowing immediate availability. Autologous therapy, however, uses a patient's own cells or tissues, which are collected, processed outside the body, and then reintroduced to the same individual.</p><h2 class="st-heading-2">How Did Stocktwits Users React?</h2><p>On Stocktwits, retail sentiment around <a href="https://stocktwits.com/symbol/CRBU">CRBU stock</a> stayed within the ‘bearish’ territory over the past 24 hours, while message volume stayed at ‘low’ levels.</p><p>CRBU stock is up 52% this year and approximately 3% over the past 12 months.&nbsp;</p><p>Read also: <a href="https://stocktwits.com/news-articles/markets/equity/ford-sales-in-us-rise-1.6-percent-in-october/cL2NX8OR3CR">Ford Sales In US Rise 1.6% In October On Continued Truck Demand</a></p><p><i>For updates and corrections, email newsroom[at]stocktwits[dot]com.</i></p>

Caribou Biosciences Stock Soars Pre-market On Positive Early Trial Data For  Cancer Treatments

The company announced positive data from trials of CB-011 and Vispa-cel in relapsed or refractory multiple myeloma and B-cell non-Hodgkin lymphoma, respectively. 

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