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Vanda Pharmaceuticals, Inc. engages in the development and commercialization of therapies for high unmet medical needs. The firm intends to treat schizophrenia, jet lag disorder, atopic dermatitis, central nervous system disorders, and circadian rhythm sleep disorder. Its product portfolio includes HETLIOZ, Fanapt, Tradipitant, Trichostatin, and AQW051. The company was founded by Mihael Hristos Polymeropoulos and Argeris N. Karabelas in 2002 and is headquartered in Washington, DC.

Vanda Pharmaceuticals Inc

Vanda Pharmaceuticals is trending after receiving FDA approval for BYSANTI (milsaperidone) to treat bipolar I disorder and schizophrenia, a new chemical entity with patent protection until 2044. The community is highly bullish, anticipating a significant re-rating, a potential short squeeze, and buyout speculation, with conversations also noting the long-term blockbuster potential of its Tradipitant pipeline.

CrowdStrike Holdings, Inc. provides cybersecurity products and services to stop breaches. It offers cloud-delivered protection across endpoints, cloud workloads, identity and data, and threat intelligence, managed security services, IT operations management, threat hunting, Zero Trust identity protection, and log management. CrowdStrike serves customers worldwide. The company was founded by George P. Kurtz, Gregg Marston, and Dmitri Alperovitch on November 7, 2011 and is headquartered in Austin, TX.

Crowdstrike Holdings Inc - Ordinary Shares - Class A

Crowdstrike Holdings Inc

Crowdstrike is trending due to a broad cybersecurity sector sell-off, following Anthropic's launch of Claude Code Security, an AI tool for vulnerability management. While some fear AI disruption will compress valuations, many in the community contend the reaction is an overblown misunderstanding, arguing Claude's code scanning does not directly compete with Crowdstrike's core enterprise endpoint and cloud protection.

NIO, Inc. is a holding company which engages in the design, manufacture, and sale of electric vehicles. Its products include the EP9 supercar and ES8 7-seater SUV. It provides users with home charging, power express valet services, and other power solutions including access to public charging, access to power mobile charging trucks, and battery swapping. It also offers other value-added services such as service package, battery payment arrangement, and vehicle financing and license plate registration. The company was founded by Bin Li and Li Hong Qin on November 28, 2014 and is headquartered in Jiading, China.

NIO Inc - ADR

NIO Inc

NIO is trending as record-breaking battery swap numbers and increased institutional investment fuel optimism for upcoming profitability. The community is actively debating if perceived market manipulation, particularly around options expiration, is suppressing the stock from a significant breakout.

JFrog Ltd. engages in the provision of an end-to-end, hybrid, universal development operations platform that powers and controls the software supply chain, which enables organizations to continuously and securely deliver software updates across any system. It operates through the following geographical segments: United States, Israel, India, and Rest of World. The firm is also involved in creating software delivered without friction from developer to device. The company was founded by Frederic Simon, Shlomi Ben Haim, and Yoav Landman in 2008 and is headquartered in Sunnyvale, CA.

JFrog Ltd

JFrog (FROG) is trending after a sharp sell-off, impacting the broader cybersecurity sector, following Anthropic's release of Claude Code Security; however, the community widely questions if the market's reaction is an overdone misinterpretation of FROG's core software supply chain security value.

LyondellBasell Industries NV engages in the refinery and production of plastic resins and other chemicals. It operates through the following segments: Olefins and Polyolefins-Americas; Olefins and Polyolefins-Europe, Asia, International; Intermediates and Derivatives; Advanced Polymer Solutions; Refining; and Technology. The Olefins and Polyolefins-Americas segment produces and markets olefins and co-products, polyethylene and polypropylene. The Olefins and Polyolefins-Europe, Asia, International segment also offers olefins and polyolefins. The Intermediates and Derivatives segment includes propylene oxide and its derivatives; oxyfuels and related products; and intermediate chemicals. The Advanced Polymer Solutions segment produces and markets compounding and solutions, such as polypropylene compounds, engineered plastics, masterbatches, colors and powders, engineered composites, and advanced polymers. The Refining segment refines heavy, high-sulfur crude oil and other crude oils of varied types and sources. The Technology segment develops chemical and polyolefin process technologies and manufactures and sells polyolefin catalysts. The company was founded in December 2007 and is headquartered in London, the United Kingdom.

LyondellBasell Industries NV - Ordinary Shares - Class A

LyondellBasell (LYB) is primarily trending due to a significant dividend cut, reported by some as a 50% reduction, which has left many income-focused investors exiting their positions. While anticipated by some due to persistent challenges in the chemicals sector and declining free cash flow, the stock's surprising resilience in the face of the cut is a key point of community discussion amid broader concerns about industry oversupply and weak sentiment.

Rich Sparkle Holdings Ltd. engages in the provision of financial printing and corporate services. The firm offers typesetting, proofreading, translation, design, and printing of listing documents, financial reports, fund documents, circulars, and announcements. It also delivers advisory services, such as conducting internal control assessment and environmental, social and governance performance evaluation, and other services including provision of co-working space. The company was founded in 2016 and is headquartered in Hong Kong.

Rich Sparkle Holdings Ltd.

Rich Sparkle Holdings Limited

Rich Sparkle Holdings (ANPA) is experiencing extreme volatility following its acquisition of TikTok icon Khaby Lame's core company in a substantial share deal and a private placement, igniting a heated community debate over its high valuation, low float, and potential for a massive short squeeze akin to other "Hong Kong" runners.

Braze, Inc. operates a customer relationship management platform for mobile applications. Its application combines messaging, audience segmentation, analytics and user support in a single integrated solution. The firm offers push notifications, email, in-app messages, and news feed services. The company was founded by Mark Ghermezian, William Magnuson, and Jonathan Hyman in 2011 and is headquartered in New York, NY.

Braze Inc - Ordinary Shares - Class A

Braze Inc

Braze Inc. is seeing significant community discussion following a strong Q2 earnings beat and raised full-year guidance, with investors debating its 'undervalued' status and strong cash position amidst the broader volatility in the software sector.

Madrigal Pharmaceuticals, Inc. engages in the development and commercialization of innovative therapeutic candidates for the treatment of cardiovascular, metabolic, and liver diseases. Its lead product, MGL-3196, is used for the treatment of non-alcoholic steatohepatitis and familial hypercholesterolemia. The company was founded by Rebecca A. Taub, Frederick Bernard Craves, and Edward Chiang on March 10, 2000 and is headquartered in West Conshohocken, PA.

Madrigal Pharmaceuticals Inc

Madrigal Pharmaceuticals is trending amidst a community debate following its latest earnings report, which showed robust revenue growth driven by its leading MASH drug, Rezdiffra, but also a wider loss due to significantly increased operating expenses. Investors are weighing the drug's strong market penetration and long-term potential against management's spending and the lack of a clear timeline for profitability in the rapidly expanding MASH sector.

Zscaler, Inc. engages in the provision of a cloud-based internet security platform. It offers Zero Trust Exchange, Zscaler Client Connector, Zscaler Internet Access, Zscaler Private Access, Zscaler B2B, Zscaler Cloud Protection, and Zscaler Digital Experience. The company was founded by Jagtar Singh Chaudhry and K. Kailash in September 2007 and is headquartered in San Jose, CA.

Zscaler Inc

Zscaler is trending amidst a sharp sector-wide sell-off, driven by fears that new AI security tools will disrupt established cybersecurity offerings, a narrative heavily debated among investors. While many view the deep valuation dip as an opportunity, others remain cautious about the company's immediate future outlook and business fundamentals.

Cornerstone Strategic Value Fund is a management investment company that is an investment operation. They limit the fund's investment in securities issued by other investment companies.

Cornerstone Strategic Investment Fund Inc.

Cornerstone Strategic Investment Fund, Inc.

Cornerstone Strategic Investment Fund ($CLM) is trending as the community intensely debates its recently announced Rights Offering (RO), with many anticipating a price dip post-RO while others see the current decline as a buying opportunity given its attractive monthly dividend and discounted NAV DRIP.

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$PLX Published this month in the journal of International Urology and Nephrology 
https://link.springer.com/article/10.1007/s11255-024-04042-4

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Thomas Prindle

Fabry Disease (FD) is a genetic disease caused by a deficiency in the activity of lysosomal galactosidase A (α-GalA), an enzyme responsible for the catabolism of globotriaosylceramide (Gb3). Since lysosomes are present throughout the body and play a crucial role in catabolism and recycling of cytosolic compounds, FD can affect multiple organs and result in various symptoms, including renal, cardiovascular, neurological, cutaneous, and ophthalmic manifestations.