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Ardelyx shares slipped nearly 6% in after-hours trading on Monday after the company said it may sell up to $100 million in stock through Jefferies, just days after delivering its strongest quarter of the year that sent the shares surging to their biggest one-day gain since May 2024.
Potential Capital Raise
The company also filed a shelf registration statement with the U.S. Securities and Exchange Commission that will allow it to sell stock, debt, or other securities periodically as a “well-known seasoned issuer.”
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Jefferies signed a new agreement with Ardelyx that allows the biotech to sell up to $100 million of its common stock through an at-the-market offering. The bank would receive a commission of up to 3% of the proceeds.
The filing gives Ardelyx room to raise cash for operations and pipeline work. However, the announcement sparked concerns about share dilution.
Last week, Ardelyx reported third-quarter revenue of $110.3 million, up 12% from a year earlier, powered by Ibsrela’s 92% jump in sales to $78.2 million and steady 9% growth in Xphozah revenue to $27.4 million.
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Margins continued to improve, with gross-to-net deductions holding steady at around 31% for Ibsrela and 29% for Xphozah.
The company’s net loss narrowed sharply to about $1 million, compared with $19.1 million in the previous quarter, as sales rose and costs were kept in check.
Research expenses rose to $18.1 million with the addition of new programs, while SG&A was essentially flat at $83.6 million. The company had cash and short-term investments of $242.7 million at the end of September.
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Following the strong report, Ardelyx raised its full-year forecast for Ibsrela revenue to $270-$275 million, reflecting sustained demand and a growing base of prescribers.
It also reaffirmed a long-term peak sales target of $750 million for Xphozah, despite reimbursement challenges under Medicare’s Transitional Drug Add-on Payment Adjustment (TDAPA) program.
The company expects Xphozah’s gross-to-net deductions to remain near 29% through the fourth quarter, and said patient access and prescription fulfillment are improving through its ArdelyxAssist support program.
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On Stocktwits, retail sentiment for Adelyx was ‘extremely bullish’ amid ‘extremely high’ message volume.

One user said the filing was a standard precaution to ensure flexibility and support future growth, adding that CEO Michael Raab had consistently delivered results and could drive the company toward an eventual buyout.
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Another user noted that the new $100 million shelf replaces a 2023 program that still had unused capacity and called it a routine housekeeping move rather than a sign of financial stress.
Adelyx’s stock has risen 17% so far in 2025.
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