Why Did SILO Stock Soar 85% Today?

• The patent was given to an application titled “Prophylactic Efficacy of Serotonin 4 Receptor Agonists Against Stress.”
• CEO Eric Weisblum stated that the patent bolsters the company's position in the mental health market, which remains a “massive and underserved market”.
• Silo's PTSD therapy program is licensed exclusively from Columbia University

Shares of Silo Pharma surged past 85% premarket on Tuesday after the European Patent Office indicated its intent to grant a patent to the company’s post-traumatic stress disorder prevention therapy application. 

This therapy was exclusively licensed from Columbia University. The patent application, titled "Prophylactic Efficacy of Serotonin 4 Receptor Agonists Against Stress," covers ways to prevent stress-induced fear and depressive-like behavior with the help of selected 5-HT4 receptor agonists. 

The company stated it's a different approach that addresses stress resilience, unlike traditional PTSD therapies, where symptoms are managed after trauma.

​Silo Pharma said it is looking to protect its patents and gain key national validations to maximize geographic coverage and long-term value.

​SILO’s Global Intellectual Property Expansion

​The company called this grant a ‘high-value milestone’ that strengthens its global intellectual property position.

“We believe this approach represents a compelling shift toward proactive treatment of stress-related disorders, which remain a massive and underserved market,” said Chief Executive Officer Eric Weisblum. 

Earlier in February 2026, the company had announced that it received a Notice of Allowance from the Japanese patent office for an application that covers SPC-15, Silo’s novel intranasal therapeutic for PTSD. 

Additionally, last year, it also got a patent from the Australian patent office for its invention titled “Prophylactic efficacy of serotonin 4 receptor agonists against stress,” exclusively licensed to Silo by Columbia University.

How Did Retail Traders React?

According to Stocktwits data, sentiment surrounding the stock has remained ‘Extremely Bullish’, while message volume has also pushed the volume meter to ‘Extremely High’ levels.

One user on Stocktwits said the stock could break out if it received IND approval.

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