Exchange: NASDAQ·Updated 07:18 AM EDT
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ARCT Arcturus Therapeutics Holdings Inc

$12.96
$0.09
(0.70%)
Pre-Market
Prev Close $12.87
EarningsNov 9
Mkt Cap$362.82M
Vol554.00

About ARCT

Arcturus Therapeutics Holdings, Inc. operates as a late-stage clinical mRNA medicines and vaccine company, which engages in the development of infectious disease vaccines and significant opportunities within liver and respiratory rare diseases. Its products include LUNAR-COV19, LUNAR-FLU, LUNAR-OTC, and LUNAR-CF. The company was founded in 2013 and is headquartered in San Diego, CA.
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Neutral Sentiment

How do you feel about ARCT?

Nganlm
$ARCT With Lunar2.0, Arcturus can now expand into other therapeutic targets such as PKU and Gout, and potentially other liver indications as well. Hence, I strongly believe market is currently very underestimating the potential of Lunar2.0. Imaging making a different mRNA construct for other liver diseases and using Lunar2.0 which is a highly effective delivery system that provides a 38 fold increase in potency for the target liver enzyme, it could be a Plug and Play model system going forward. The vehicle stays the same, ie the LNP, the cargo changes, example for OTC deficiency, can load mRNA that codes for OTC enzyme, for PKU, switch the cargo to mRNA that codes for PAH enzyme and for Gout, switch it to an mRNA sequence that targets uric acid clearance. Just my own thinking….very bullish….
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Januszekf
$ARCT ​Berween late 2026 through the first half of 2027, Arcturus is positioned to pursue up to three strategic licensing transactions— KOSTAIVE , an ARCT-810 Phase 3 partnership, and a second liver indication—potentially generating $200M to $300M in upfront payments or more if an influenza or oncology platform partnership is executed.
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Yooman
$ARCT Moderna at 80 Billion MC. His little brother (or sister) at 400 Million. But one day she'll grow up, too. She's already very smart.😎😀
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Sumdum_Phuq
$ARCT Take a few minutes and research myNEO Therapeutics for yourself. For those not paying attention, this is the company Arcturus just acquired. Seems their main focus is in cancer research. Even Sumdumphuq can see how bright the future is for Arcturus.
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Choice79
$ARCT well, not the blowout news we were hoping for but good long term news. Lunar 2.0, positive data on otc and good plans moving forward. We should move up from here. It’s the makings of a good, solid company for years to come. Soon our market cap will be measured in the billions, not hundreds of millions.
11
King316
$ARCT OTC Phase 2 proves the concept works. Switching to LUNAR 2.0 with 38x higher expression makes sense for lower doses and a better drug. Delay sucks, but it’s the right move long term. Buying the dip.
11
birdflustocks
$ARCT Wednesday, September 23, 2026, at 4:30 p.m. ET. The presentation will provide an overview of the ARCT-810 Phase 2 clinical program for Ornithine transcarbamylase (OTC) deficiency and Arcturus’ mRNA liver therapeutics platform. Prior to the call, the Company will issue a press release summarizing the presentation.
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Januszekf
$ARCT Joseph Payne today : "COVID vaccine opportunity is larger than shingles and RSV combined. It is a very large market opportunity and we've already showcased that we have superior, already, over the market leader and we have complete control over that asset. So stay tuned as we build that asset out commercially... it's going to be an interesting asset to follow."
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Januszekf
$ARCT Upcoming catalysts for ARCT: Out-licensing the Seasonal Flu Phase 2-ready sa-mRNA quadrivalent vaccine , partnering the BARDA backed pandemic influenza asset, securing a regional commercial distributor for KOSTAIVE in Europe and the UK, Advancing KOSTAIVE toward U.S. BLA filing
10
2PacalypseNow4Life
$ARCT nobody knows nothjng. just funds hedging their positions.. volume on both puts and calls is way too low. if someone actually knew something youd be seeing 20,000+ volume on puts or calls.
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King316
$ARCT Key takeaway from today's presentation with Joe: ARCT-032 isn't just targeting Class 1 patients anymore—it could potentially benefit ALL CF patients. That expands the addressable market way beyond what most people were initially pricing in. Also really interested to hear what comes out of the upcoming platform update. Definitely holding strong here
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Yooman
$ARCT The more I look into Arcturus and think about it, the more I’m convinced that this company—which is still relatively unknown at this stage but is making great strides with its mRNA approach—has a bright future ahead, unless a major player acquires it.
8
Choice79
$ARCT wall st analysts have just upgraded Arct from buy to strong buy. I would expect more upgrades to come.
9
Nganlm
$ARCT Yesterday, the presentation highlighted very positive results for 810, therapy for OTC deficiency. In the latest set of results, ammonia and glutamine levels are reduced and within normal range. This implies that 810 works and demonstrated highly encouraging efficacy and safety profiles. The huge surprise is the unveiling of Lunar2.0, its next generation mRNA delivery platform. This is a massive structural upgraded platform that future iterations can likely offer far lower, safer and less frequent dosing cycles. The fact that the FDA gives them the green light to immediately integrate their next-gen candidate ARCT2601 into the ongoing Phase 2 study is proof of the confidence and promise in the delivery system.
9
Sully1026
$ARCT Feeling better than ever about this stock. It will just take a little longer to get there. But when it does, it’s going to explode.
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Choice79
$ARCT new article on seeking alpha. Says that tomorrow is going to move the stock significantly. Hence the large volume of options.
9
EnigmaticFan
$ARCT OTC data and regulatory path should be unveiled at their presentation at the global investment conference tomorrow morning.
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Nganlm
$ARCT Just listened to Cantor Fitzgerald conference by CEO Joe Payne. It was amazing. His explanations on 810, 032, Kostaive and cancer vaccine. Do listen in if you have the time.
9
Den00
$ARCT It will not be surprised if a partnership with Biontech come soon. They are left behind with competition. Also Gout is a good indication for sure revenues if gene editing become available broadly. There is no Gene at all. Very smart.
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Yooman
$ARCT Today’s price action: Very nice. This means that the market—or rather, market participants, and thus primarily the buyers—have clearly viewed Arctur’s “data” and intentions in a positive light. The price action has spoken for itself. I’m looking forward to the price on December 31, 2026. We’re part of the mRNA revolution—in fact, we’re the first. Here’s to the future!
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