Mavi93
$CTMX The criticism overlooks the very purpose of PROBODY technology. Yes, EpCAM is also expressed on healthy cells, but that’s exactly why the masking technology was developed: the drug is designed to be activated by tumor-associated proteases within the tumor microenvironment. Varseta-M should therefore not be equated with previous, unmasked EpCAM ADCs. The assumption that AIBW dosing automatically reduces efficacy is also unproven. The upcoming clinical data will be decisive. $CTMX
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