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Tilray Brands, Inc. engages as a consumer packaged goods company, which focuses on medical cannabis research and the cultivation, processing, and distribution of cannabis products worldwide. It operates through the followings segments: Cannabis, Distribution, Beverage, and Wellness. The Cannabis segment focuses on cultivation, production, distribution, and sale of both medical and adult-use cannabis products. The Distribution segment is involved in purchase, resale, and distribution of pharmaceutical and wellness products. The Beverage segment refers to the production, marketing, and sale of beverages. The Wellness segment represents the production, marketing, and distribution of hemp-based food and other wellness products. The company was founded on January 24, 2018 and is headquartered in Leamington, Canada.

Tilray Brands Inc

Tilray is trending as traders speculate on potential near-term catalysts related to cannabis rescheduling following comments from a key political figure. The community is closely watching for further developments, with some expecting a possible short squeeze and others debating the long-term fundamentals of the stock. Broader discussions include the potential impact on the cannabis industry, particularly for veterans and medical research.

AMC Robotics Corp. engages in developing and deploying AI-enabled robotics and smart security solutions, especially for warehouse automation, enterprise security, robotics patrol/incident-response and logistics automation. The company is headquartered in New York, NY.

AMC Robotics Corp.

AMCI is trending due to its recent surge, driven by excitement around its merger and potential in the robotics sector. Community members are actively discussing potential squeezes and price targets, while acknowledging the stock's volatility and low float. Bullish sentiment seems strong, with many hoping it can continue its momentum.

Pfizer Inc. is a research-based global biopharmaceutical company, which engages in the discovery, development, manufacture, marketing, sales and distribution of biopharmaceutical products worldwide. The firm works across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases. The company was founded by Charles Pfizer Sr. and Charles Erhart in 1849 and is headquartered in New York, NY.

Pfizer Inc.

Pfizer Inc

Pfizer is trending as investors digest the company's weaker-than-expected 2026 outlook, particularly concerning COVID-19 drug demand and patent expirations. The community is actively discussing the potential for dividend cuts and the need for a new growth engine beyond COVID-related revenue. Some investors are taking a long-term view, focusing on the dividend yield and potential upside from the company's pipeline.

B. Riley Financial, Inc. engages in the provision of financial services and solutions to the capital raising and financial advisory needs of public and private firms. It operates through the following segments: Capital Markets, Wealth Management, Financial Consulting, Auction and Liquidation, Communications, and Consumer. The Capital Markets segment provides investment banking, corporate finance, research, wealth management, and sales and trading services to corporate, institutional, and high net worth clients. The Wealth Management segment offers retail brokerage, investment management, and insurance, and tax preparation services. The Financial Consulting segment focuses on a variety of specialized advisory services spanning bankruptcy, restructuring, turnaround management, forensic accounting, crisis and litigation support, appraisal and valuation, real estate, and operations management. The Auction and Liquidation segment deals with retail liquidation services. The Communications segment is composed of a portfolio of companies acquired for attractive risk-adjusted investment return characteristics. The Consumer segment includes Targus and the Brands investment portfolio. The company was founded in 1973 and is headquartered in Los Angeles, CA.

B. Riley Financial Inc

B. Riley Financial is trending due to a swing to profitability revealed in their Q2 earnings filing, which has sparked a surge in intraday trading. The community is discussing the potential for a turnaround squeeze, citing high short interest and a low float, drawing parallels to CVNA's past performance. Positive catalysts and debt restructuring are also key talking points.

Aldeyra Therapeutics, Inc. is a biotechnology company, which engages in research and development activities with related general business planning, including raising capital. It engages in the discovery of therapies designed to treat immune-mediated diseases. The company was founded by Thomas A. Jordan and John E. Dowling on August 13, 2004 and is headquartered in Lexington, MA.

Aldeyra Therapeutics Inc

ALDX is trending due to anticipation surrounding its upcoming FDA decision on its dry eye drug, reproxalap, with the community actively debating the likelihood of approval after previous setbacks. Discussions also involve the potential impact of a new RASP pipeline focus and a collaboration with AbbVie. Community members are weighing the potential for a short squeeze and a significant price movement based on the FDA's verdict.

Affirm Holdings, Inc. operates a platform for digital and mobile-first commerce. Its platform consists of three core elements: a point-of-sale payment solution for consumers, merchant commerce solutions, and a consumer-focused app. The company was founded by Max R. Levchin in 2012 and is headquartered in San Francisco, CA.

Affirm Holdings Inc - Ordinary Shares - Class A

Affirm Holdings Inc

Affirm is trending amid anticipation for upcoming earnings, with analysts projecting significant EPS growth. Community discussions include speculation on the potential impact of consumer credit trends and the company's valuation. The stock is exhibiting volatility, influenced by broader market sentiment and sector-specific news.

The 401jk (just kidding) meme is a satirical punch in the gut in the face of the concept of retirement and also the 401k. The 401k total holdings are valued at around $12 trillion USD and it is the most popular retirement savings plan in the US. As time passes forevermore true retirement, or as we like to call it real freedom will only become much harder and harder for people to attain.  Through meme fueled laser focus and cyperphunk ideology the 401jK meme retirement fund token and community aim to point out the absurdities of how rigged our current system is, and how only insiders and those with power are starting the benefit from the increased centralization of cryptocurrency.........while also aiming to flip the $12 trillion USD 401k system to achieve freedom before our backs and knees are breaking.

401jK

401JK is trending as the community rallies around the launch of staking, with users excitedly reporting significant amounts already staked. The coin's narrative, centered on challenging traditional retirement systems, resonates with many who see it as a movement. Community members highlight the project's strong holder base and meme-driven approach.

Luckin Coffee, Inc. engages in providing food and beverage items, and operates coffee retail stores. It has a pioneered a technology-driven retail network to provide coffee and other products of high quality, high convenience and high affordability to customers. The company manages pick-up stores, relax stores, and delivery kitchens. It also offers tea, snacks, and light meals through its mobile application. The company was founded by Zhi Ya Qian, Fei Yang and Jin Yi Guo on June 16, 2017 and is headquartered in Xiamen, China.

Luckin Coffee Inc - ADR

LKNCY is trending as investors discuss the recent price drop and potential reasons behind it, including lack of liquidity, possible selling by large shareholders, and concerns about transparency. The community is actively debating whether the drop presents a buying opportunity or signals deeper issues with the company, while also speculating on the potential for relisting and acquisitions.

Biodexa Pharmaceuticals Plc is a drug delivery technology company. It is focused on the research and development of medicines for rare cancers, via both in-house programs as well as partnered programs. The firm's proprietary platform drug delivery technologies are Q-Sphera platform is a disruptive polymer microsphere technology, which is used for sustained release at the microscale to prolong and control the release of therapeutics over an extended period of time from weeks to months; Midasolve platform is an innovative nano saccharide technology, which is used to dissolve drugs at the nanoscale so that they can be administered in liquid form directly and locally into tumors; Midacore platform is an edge gold nanoparticle technology, which is used for targeting sites of disease at the nanoscale. The company was founded in 2000 and is headquartered in Cardiff, the United Kingdom.

Biodexa Pharmaceuticals Plc - ADR

Biodexa Pharmaceuticals Plc

Biodexa Pharmaceuticals is trending due to recent price volatility and community speculation about potential catalysts. Discussions revolve around its low float and potential for a short squeeze, with some eyeing it as a potential high-reward play. The stock's movements are also being compared to other recent high-flying low float stocks.

Reddit, Inc. operates an entertainment, social networking, and news website where registered community members can submit content. It provides online news services where users can select and rank web content. The firm also offers a personalized filter on the day's story, using previous votes to determine what new things the user might like to read. The company was founded by Steven Ladd Huffman and Alexis Ohanian on June 23, 2005 and is headquartered in San Francisco, CA.

Reddit Inc. - Ordinary Shares - Class A

Reddit Inc

Reddit's potential for a short squeeze is a key focus, with high short interest and rising borrowing costs fueling speculation. Additionally, the community is discussing Reddit's growth prospects relative to other social media platforms, specifically highlighting new advertising tools and earnings momentum. Some investors are anticipating inclusion in the S&P 500 as a potential catalyst.

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British drugmaker GSK Plc (GSK) on Wednesday announced that it now expects full-year earnings and turnover to be toward the top end of its guidance after its second-quarter earnings surpassed Wall Street expectations on strong sales of its specialty medicines.The company now <a target="_blank" rel="noopener noreferrer nofollow" href="https://www.gsk.com/media/zhfdbsly/q2-2025-results-announcement.pdf">expects</a> turnover growth to be toward the top end of 3% to 5% and for core earnings per share growth to be closer to 8% at constant exchange rate.On Stocktwits, retail sentiment around <a href="https://stocktwits.com/symbol/GSK">GSK</a> trended in the ‘bearish’ territory over the past 24 hours, while message volume dropped from ‘high’ to ‘normal’ levels.<figure class="image"><img style="aspect-ratio:626/62;" src="https://news.stocktwits-cdn.com/Screenshot_2025_07_30_at_8_18_14_AM_png_6f597ae2a0.webp" alt="GSK's Sentiment Meter and Message Volume as of 8:20 a.m. ET on July 30, 2025 | Source: Stocktwits" width="626" height="62"><figcaption>GSK's Sentiment Meter and Message Volume as of 8:20 a.m. ET on July 30, 2025 | Source: Stocktwits</figcaption></figure>CEO Emma Walmsley pegged the increase in guidance to another quarter of excellent performance, driven by the company’s specialty medicines segment.“We also continue to make very good progress in research and development, with 3 major FDA approvals achieved so far this year, 16 assets now in late-stage development, and 4 more promising medicines to treat cancer, liver disease and HIV expected to enter Phase III and pivotal development by the end of the year. With all this, we now expect to be towards the top end of our financial guidance for 2025 and remain confident in our long-term outlooks," the CEO said.GSK is eyeing annual sales of over £40 billion ($53.28 billion) by 2031. &nbsp;The company on Wednesday noted that its guidance is inclusive of tariffs enacted by the U.S. thus far and European tariffs indicated this week.“We are positioned to respond to the potential financial impact of tariffs, with mitigation options identified. Given the uncertain external environment, we will continue to monitor developments,” the firm said.For the second quarter, the company reported sales of about £8.00 billion, marking a growth of 6% at constant exchange rate and above an analyst estimate of £7.81 billion, according to data from Fiscal AI.Specialty medicines sales rose 15% to £3.3 billion, thanks to double-digit sales growth in Respiratory, Immunology &amp; Inflammation, Oncology, and HIV drugs at constant exchange rate.Vaccine sales, meanwhile, rose 9% to £2.1 billion while general medicines sales fell 6%.Core earnings per share came in at 46.5 pence in the three months through the end of June, up from an analyst estimate of 42 pence.NYSE-listed shares of GSK are up by over 11% this year but down by over 5% over the past 12 months.Read also: <a href="https://stocktwits.com/news-articles/markets/equity/humana-announces-upbeat-earnings-raised-guidance/choXGmPR5zr">Humana Stock Gains On Upbeat Earnings And Raised Guidance, Draws Retail Praise</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.(Exchange Rate: £1= $1.33)

In this photo illustration, the logo of GSK plc is displayed on a smartphone screen, on April 26, 2025, in Chongqing, China. (Photo illustration by Cheng Xin/Getty Images)

GSK Expects Full-Year Earnings At Top End Of Guidance: CEO Says ‘Confident In Our Long-Term Outlooks’

GSK now expects turnover growth to be toward the top end of 3% to 5% and core earnings per share growth to be closer to 8% at constant exchange rate.

Equity

U.S. Food and Drug Administration reviewers on Tuesday flagged certain concerns about GSK Plc’s (GSK) investigational cancer drug called Blenrep, including a high rate of ocular toxicities.Ocular toxicity refers to the harmful effects a substance or drug has on the eye, potentially causing damage to its structure or impairing its function.<a href="https://stocktwits.com/symbol/GSK">GSK</a> is seeking approval for the drug, also known as Belantamab Mafodotin, in the treatment of adults with multiple myeloma in combination with Bortezomib or Pomalidomide and Dexamethasone in patients who have received at least one prior line of therapy. The application is based on data from two late-stage trials.FDA reviewers <a target="_blank" rel="noopener noreferrer nofollow" href="https://www.fda.gov/media/187578/download">stated</a> in briefing documents on the regulator’s website that the benefit-risk profile of the drug for treating multiple myeloma “remains unclear,” considering efficacy results, safety and tolerability concerns, and uncertainties regarding the appropriateness of the proposed dosages.The documents were released ahead of an advisory committee meeting scheduled for Thursday. The FDA is expected to decide on approving or disapproving the drug by next week.The reviewers noted a high incidence of ocular toxicity with the treatment, including keratopathy (changes in the corneal epithelium), changes in clarity of vision, as well as other ocular symptoms, such as blurred vision and dry eyes.“The ocular toxicity, including corneal toxicity, observed with Belantamab Mafodotin is a unique toxicity that is not seen with any currently available treatments for multiple myeloma,” they said.While ocular toxicity may be asymptomatic in its early stages, it can result in severe consequences, such as loss of vision, the reviewers noted.The agency also expressed concern that the dosages of Belantamab Mafodotin have not been adequately optimized, as evidenced by the high rates of dose modifications in both trials referred to in the application.A majority of patients were not receiving the intended dosage and required frequent dose modifications, including interruptions, throughout the duration of treatment, the agency said.Blenrep was previously granted accelerated approval as monotherapy on Aug. 5, 2020, for the treatment of patients with relapsed or refractory multiple myeloma who have received at least four prior therapies. It was subsequently withdrawn on Feb. 6, 2023, due to failure of the confirmatory trial to meet its progression-free survival endpoint.On Stocktwits, retail sentiment about GSK fell from ‘bullish’ to ‘neutral’ territory over the past 24 hours while message volume remained at ‘high’ levels.<figure class="image"><img style="aspect-ratio:626/62;" src="https://news.stocktwits-cdn.com/Screenshot_2025_07_15_at_1_26_26_PM_png_1594f6ef5c.webp" alt="GSK's Sentiment Meter and Message Volume as of 1:25 p.m. ET on July 15, 2025 | Source: Stocktwits" width="626" height="62"><figcaption>GSK's Sentiment Meter and Message Volume as of 1:25 p.m. ET on July 15, 2025 | Source: Stocktwits</figcaption></figure>GSK stock is up 6% this year but down by 4% in the past 12 months.Read Next: <a href="https://stocktwits.com/news-articles/markets/equity/joby-aviation-stock-flies-on-expansion-of-marina-site/ch8Q95jR5Fw">Joby Aviation Stock Flies High On Expansion Of Marina Site, Retail Boards The Flight</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

US FDA Reviewers Highlight Safety Concerns With GSK’s Investigational Cancer Drug: Retail’s On The Fence

FDA reviewers said in briefing documents that the benefit-risk profile of the drug for the treatment of multiple myeloma “remains unclear.”

GSK plc (GSK) said on Monday that its application for extending the use of its respiratory syncytial virus (RSV) vaccine Arexvy to adults aged 18-49 who are at increased risk of contracting the disease has been accepted by the U.S. Food and Drug Administration (FDA).The vaccine is currently approved in the U.S. for the prevention of lower respiratory tract disease (LRTD) caused by RSV in adults aged 60 and older, and for those aged 50-59 years who are at increased risk. Adults can be at increased risk for RSV disease due to certain comorbidities, immune-compromised status, or advanced age.A regulatory decision by the FDA on this submission is <a target="_blank" rel="noopener noreferrer nofollow" href="https://www.gsk.com/en-gb/media/press-releases/us-fda-accepts-application-to-review-expanded-use-of-gsk-s-rsv-vaccine/">expected</a> in the first half of 2026.<a href="https://stocktwits.com/symbol/GSK">GSK</a> is continuing to seek expanded indications for its RSV vaccine in other geographies, including in the European Economic Area and Japan, the company said.RSV is a common contagious virus affecting the lungs and breathing passages and impacts an estimated 64 million people of all ages globally every year, as per GSK. RSV can exacerbate conditions, including Chronic Obstructive Pulmonary Disease (COPD), asthma, and chronic heart failure, and can lead to severe outcomes, such as pneumonia, hospitalization, and death.Arexy’s turnover fell 57% in the first quarter (Q1) of 2025 to £78 million ($105 million) due to lower demand. The company pegged the decline in sales within the U.S. partly to a more limited recommendation from the Advisory Committee on Immunization Practices for individuals aged 60 to 74.On Stocktwits, retail sentiment around GSK stayed unmoved within ‘bullish’ territory over the past 24 hours while message volume remained at ‘high’ levels.<figure class="image"><img style="aspect-ratio:1366/130;" src="https://news.stocktwits-cdn.com/Screenshot_2025_07_14_at_8_31_53_AM_png_fd0d117e35.webp" alt="GSK's Sentiment Meter and Message Volume as of 8:30 a.m. ET on July 14, 2025 | Source: Stocktwits" width="1366" height="130"><figcaption>GSK's Sentiment Meter and Message Volume as of 8:30 a.m. ET on July 14, 2025 | Source: Stocktwits</figcaption></figure>NYSE-listed shares of GSK are up by 13% this year but down by about 1% over the past 12 months.Read Next: <a href="https://stocktwits.com/news-articles/markets/equity/synopsys-ansys-35-billion-deal-reportedly-gets-china-conditional-approval/ch8Bx5yR5V8">Synopsys-Ansys’ $35B Deal Reportedly Gets China’s Conditional Approval Days Before Closure Deadline</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.(Exchange Rate: £1= $1.35)

GSK Seeks FDA Approval For RSV Vaccine In More Adults: Retail Sees No Reason To Shift Their Bullish Stance

A decision by the FDA on the new submission is expected in the first half of 2026.

Fidelity Covington Trust - Fidelity Women's Leadership

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The S&P 500 is modestly lower so far in December, putting the Santa Claus rally in question. The Santa Claus rally refers to the market’s tendency to rise in the final weeks of the year—what do you expect from December 16 through December 31?

What do you expect the S&amp;P 500’s total return to be in the second half of December?

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What do you expect the S&P 500’s total return to be in the second half of December?

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