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Capricor Therapeutics, Inc. is a clinical-stage biotechnology company, which focuses on the development of transformative cell and exosome-based therapeutics for treating Duchenne muscular dystrophy (“DMD”), a rare form of muscular dystrophy which results in muscle degeneration and premature death, and other diseases with unmet medical needs. Its product candidate consists of CAP-1002, Engineered Exosomes, CAP-2003, and Exosome-Based Vaccine. The company was founded on June 17, 1996 and is headquartered in San Diego, CA.

Capricor Therapeutics Inc

Attention centers on the approaching FDA decision on Capricors deramiocel for Duchenne muscular dystrophy, with traders weighing the companys amended application and longer-term upper-limb data alongside recent FDA discussion of flexibility in rare-disease reviews. Many are bullish and read commercial hiring as a sign of launch preparation, while skeptics stress that approval is uncertain given the earlier negative review and debate over the evidence; some also cite Inovios separate FDA approval as a positive sentiment signal.

TG Therapeutics, Inc. engages in the acquisition, development, and commercialization of novel treatments for B-cell malignancies and autoimmune diseases. Its product pipeline includes TG-1501, TG-1701, Ublituximab, and Umbralisib. The company was founded by Michael Sean Weiss and Laurence H. Shaw on May 18, 1993 and is headquartered in Morrisville, NC.

TG Therapeutics Inc

A push to a fresh 52-week high is drawing attention ahead of an expected Q3 earnings update, while traders debate whether the rally reflects business momentum, short-covering, or speculation about an unconfirmed buyout.

Precigen, Inc. is a biotechnology company, which engages in the research and development of synthetic biology technologies. It operates through the Biopharmaceuticals and Exemplar segments. The company was founded by Thomas David Reed in 1998 and is headquartered in Germantown, MD.

Precigen Inc

Inovios FDA approval of a competing treatment for recurrent respiratory papillomatosis has raised concerns about new competition for Precigens PAPZIMEOS. Traders debate the threat: some see a serious challenge, while others argue Precigen retains an advantage from its commercial head start and full approval, and view the selloff as an overreaction.

Okta, Inc. engages in the provision of an identity management platform for enterprises. The firm operates through the following geographical segments: United States and International. Its products include single sign-on, multi-factor authentication, access gateway, API access management, authentication, adaptive MFA and lifecycle management. The company was founded by Todd McKinnon and J. Frederic Kerrest in 2009 and is headquartered in San Francisco, CA.

Okta Inc - Ordinary Shares - Class A

Okta Inc

Oktas stronger-than-expected quarterly results and raised outlook, alongside growing interest in identity security for AI agents, have driven a sharp rally. Traders are divided between seeing durable cybersecurity demand and warning that the move has outrun the companys growth, with valuation concerns and profit-taking weighing on shares.

CorMedix, Inc. is a pharmaceutical and medical device company, which engages in the development and commercialization of therapeutic products for the prevention and treatment of diseases and conditions. The company was founded by Antony E. Pfaffle on July 28, 2006 and is headquartered in Berkeley Heights, NJ.

CorMedix Inc

DaVitas warning that Medicare reimbursement for DefenCath could decline after early 2027 has fueled concerns about pricing and CorMedixs largest revenue driver. Traders are divided: some see the comments as a serious commercial risk, while others argue DaVitas outlook is preliminary and point to CMSs reimbursement estimate as a counterweight.

Mineralys Therapeutics, Inc. is a clinical-stage biopharmaceutical company, which focuses on developing medicines to target diseases driven by abnormally elevated aldosterone. Its clinical-stage product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor that are initially developing for the treatment of cardiorenal conditions affected by abnormally elevated aldosterone, including hypertension and chronic kidney disease. The company was founded by Brian Taylor Slingsby on May 31, 2019 and is headquartered in Radnor, PA.

Mineralys Therapeutics Inc

MLYS is under pressure amid concerns that the slow early commercial ramp for AstraZenecas competing hypertension drug could signal a challenging launch and weaker near-term sales prospects for lorundrostat. Traders disagree on whether that undermines Mineralyss commercial outlook, with some emphasizing the upcoming FDA decision and clinical data while others question its ability to compete independently.

AppLovin Corp. engages in the development and operation of a mobile marketing platform. It offers AppDiscovery, MAX, Adjust, and SparkLabs. Its software-based platform caters to mobile application developers to improve the marketing and monetization of applications. The company was founded by Andrew Karam, John Krystynak, and Adam Foroughi in 2011 and is headquartered in Palo Alto, CA.

Applovin Corp - Ordinary Shares - Class A

Applovin Corp

AppLovins steep selloff and fresh lows ahead of its earnings report are driving attention, with analyst price-target cuts and concerns about advertising demand adding pressure. Traders are split between viewing the decline as excessive given the companys growth and profitability, and worrying that weaker ad-market signals or an earnings disappointment could prolong the slide.

BNB (BNB) is a cryptocurrency . BNB has a current supply of 131,511,396.41. The last known price of BNB is 698.79071116 USD and is down -6.08 over the last 24 hours. It is currently trading on 3523 active market(s) with $4,017,835,584.29 traded over the last 24 hours. More information can be found at https://bnbchain.org/en.

Binance

A reported major Binance security breach, with withdrawals temporarily suspended and billions in crypto reportedly affected, is driving attention to BNB and broader crypto-market concerns. Traders are debating whether the incident threatens trust in Binance and warrants further selling, while others view the selloff as an overreaction; claims of an inside job remain speculation.

Permian Resources Corp. is an oil and natural gas company, which focuses on returns to stakeholders through the responsible acquisition, optimization and development of crude oil and associated liquids-rich natural gas reserves. The company was founded on December 18, 2025 and is headquartered in Midland, TX.

Permian Resources Holdings Inc. - Ordinary Shares - Class A

Permian Resources Corp - Ordinary Shares - Class A

Permian Resources is being discussed amid volatile crude prices and shifting Middle East supply risks, especially tensions and shipping disruptions around the Strait of Hormuz. Traders debate why PR often fails to track oils moves, while some point to the companys production growth, guidance and dividends as support for a longer-term bullish view.

Centrus Energy Corp. engages in the supply of nuclear fuel and services for the nuclear power industry. It operates through the Low-Enriched Uranium (LEU) and Technical Solutions segments. The LEU segment includes various components of nuclear fuel to utilities from its global network of suppliers. The Technical Solutions segment offers advanced engineering, design, and manufacturing services to government and private sector customers, and is deploying advanced nuclear fuel production capabilities to power existing, and next-generation reactors around the world. The company was founded in October 1992 and is headquartered in Bethesda, MD.

Centrus Energy Corp - Ordinary Shares - Class A

Centrus Energy Corp 

Centruss steep selloff is the dominant topic, with traders citing share dilution and the cost and execution risks of expanding enrichment capacity, alongside weakness across nuclear stocks. Bulls point to its strategic U.S. HALEU supply role and government contracts as long-term support, while others question the valuation and whether the decline has further to run.

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Fulcrum Therapeutics, Inc. is a clinical stage biopharmaceutical company, which develops new medicines and focuses on unlocking gene control mechanisms to develop small molecule therapies. Its product candidate includes Losmapimod and FTX-HbF. The company was founded by Michael R. Green, Danny Reinberg, Rudolf Jaenisch, Jeannie T. Lee, and Bradley E. Bernstein on August 18, 2015, and is headquartered in Cambridge, MA.

Fulcrum Therapeutics Inc

Why Did FULC, MVIS, HRTX Stocks Plunge To 52-Week Lows Today? 

Equity

Neutral Sentiment

<ul class="summary-bullets"><li>Fulcrum shares plunged to a 52-week low of about $2.90 after the company halted development of its lead sickle cell disease drug, pociredir.</li><li>Heron shares fell to a record low of $0.44 after a federal court invalidated patents covering its cancer-supportive care drug CINVANTI.</li><li>MicroVision shares slumped after the company proposed a reverse stock split.&nbsp;</li></ul>Fulcrum Therapeutics (FULC), Heron Therapeutics (HRTX) and MicroVision (MVIS) suffered steep losses on Tuesday, with each stock falling to fresh 52-week lows as investors reacted to significant setbacks affecting their core business prospects.<a href="https://stocktwits.com/symbol/FULC">Fulcrum Therapeutics</a> and&nbsp;<a href="https://stocktwits.com/symbol/HRTX">Heron Therapeutics</a> stocks plunged by over 51% and 45%, respectively, and&nbsp;<a href="https://stocktwits.com/symbol/MVIS">MicroVision stock&nbsp;</a>slumped by nearly 32%.&nbsp;<h2 class="st-heading-2">FULC Faces Pipeline Crisis</h2>Fulcrum recorded the largest decline of the group, with shares tumbling to a 52-week low of $2.9, as the company announced on Monday that it would discontinue development of pociredir, its leading treatment candidate for sickle cell disease.The move came after the U.S. Food and Drug Administration raised concerns about possible cancer risks linked to the treatment. Since the drug was a major part of Fulcrum’s growth plans, analysts lowered their expectations for the company.&nbsp;Following the development, Fulcrum faced a wave of analyst downgrades on Tuesday. JPMorgan downgraded the stock by two levels, moving it to ‘Underweight’ from ‘Overweight’.According to JPMorgan, Fulcrum's ongoing strategic review may not be enough to offset the impact of losing its lead asset. Leerink also adopted a more cautious stance, downgrading FULC stock to ‘Market Perform’ from ‘Outperform’. The firm simultaneously slashed its price target to $4 from $24.However, on Stocktwits, retail sentiment around the stock remained in ‘extremely bullish’ territory.&nbsp;<h2 class="st-heading-2">Patent Setback Hits HRTX</h2>Heron also came under heavy pressure with the stock plunging to a record low of $0.44 after a federal court ruling invalidated patents tied to CINVANTI, one of the company’s important cancer-supportive care products.The ruling could allow generic versions of the drug to enter the market sooner than expected, hurting Heron’s sales. CEO Craig Collard said the company will appeal the decision.&nbsp;Following the update, Needham downgraded Heron to ‘Hold’ from ‘Buy’. Retail sentiment around the stock changed to ‘extremely bullish’ from ‘bullish’ territory the previous day.&nbsp;<h2 class="st-heading-2">MVIS Seeks Reverse Stock Split Approval&nbsp;</h2>MicroVision stock hit a 52-week low of $0.4 after the company asked its shareholders to approve a reverse stock split proposal. The proposal will be presented at the company's virtual annual shareholder meeting scheduled for July 10, where investors will vote on several measures.If successful, MicroVision's board would gain the ability to combine shares at a ratio ranging from 1-for-5 to 1-for-15. The lidar company said the measure is intended to support compliance with Nasdaq's minimum bid-price requirement. Retail sentiment around the stock remained in ‘bearish’ territory.&nbsp;So far this year, MVIS, FULC, and HRTX stocks have plunged between 50% and 72%.&nbsp;Also See:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/black-berry-stock-surges-overnight-cfo-ai-vision-retail-debates-meme-mania-growth-story/cZ0SpWqReDn">BlackBerry Stock Surges Overnight As CFO Stands Firm On AI Vision — Retail Debates Meme Mania Vs Growth Story</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

In this photo illustration, the Fulcrum Therapeutics logo is seen displayed on a smartphone screen.

Fulcrum Therapeutics (FULC), Heron Therapeutics (HRTX) and MicroVision (MVIS) suffered steep losses on Tuesday, with each stock falling to fresh 52-week lows as investors reacted to significant setbacks affecting their core business prospects.

The selloff highlighted the risks facing smaller companies operating in biotechnology and emerging technology. 


Heron Therapeutics Inc

Microvision Inc

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Fed decision day is here - Kevin Warsh chairs his first FOMC meeting with markets pricing a hold at 3.50%-3.75% but watching for a hawkish shift. Vote on what you expect to be decided today, then drop your prediction for the first rate cut or hike in the comments.

What do you expect the Fed to decide at its FOMC meeting today? 
 
Drop a comment with when you expect the first cut/hike to be.

Current Price	$3.71
Prev Close	$3.77
Open	$3.74
Dividend Yield	0.00%
50-Day Moving Average	$3.76
Beta	1.22
Avg. Volume	1.43M
PE Ratio	-3.11

52-Week High	$15.74
52-Week Low	$2.83
Market Capitalization	$287.64M
EPS (Annual)	-$1.18
Price to Book	0.93
Revenue Per Employee	$0.00

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