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Celsius Holdings, Inc. engages in the development, marketing, sale, and distribution of functional drinks and liquid supplements. It also offers post-workout functional energy drinks and protein bars. The company was founded in April 2004 and is headquartered in Boca Raton, FL.

Celsius Holdings Inc

Celsius is trending as investors grapple with a significant disconnect between record-breaking quarterly financial performance and a suppressed stock price. The community is actively debating whether the current price action is driven by institutional manipulation, sector-wide consumer softness, or concerns regarding brand cannibalization and competitive pressure from rivals.

iShares Silver Trust - Fractional undivided beneficial interests

iShares Silver Trust

The iShares Silver Trust is capturing significant investor attention as market participants debate whether silver is entering a long-term breakout cycle driven by rising industrial demand and supply chain concerns. Community sentiment is deeply divided, with many traders actively discussing potential short squeezes and hedging strategies while others remain skeptical about the sustainability of current price action amidst broader macroeconomic volatility.

Twin Vee PowerCats Co. engages in the design, manufacture, and sale of recreational and commercial power catamaran boats. The firm is focused on designing and developing its products under the ELECTRA Power Sports brand. It operates through the Twin Vee PowerCats and Wizz Banger, Inc. Segments. The Twin Vee PowerCats segment designs, manufactures, and sells recreational and commercial powerboats. The Wizz Banger, Inc. segment refers to a development-stage subsidiary with plans to develop an innovative online marketplace leveraging artificial intelligence (AI) to transform how customers search for and purchase recreational marine assets. The company was founded by Roger Dunshee in 1996 and is headquartered in Fort Pierce, FL.

Twin Vee PowerCats Co

Twin Vee PowerCats is seeing significant retail interest driven by its ultra-low micro-float status and momentum following a reverse stock split. The community is actively discussing the stock's squeeze potential, drawing comparisons to other high-volatility runners and pointing to recent insider buying as a catalyst for a potential parabolic move.

Moonlake Immunotherapeutics operates as a clinical-stage biotechnology company. It offers tri-specific Nanobody, Sonelokimab to address significant unmet needs in inflammatory skin and joint diseases. The company was founded by Kristian Reich, Jorge Santos da Silva, and Arnout Ploos van Amstel in 2021 and is headquartered in Zug, Switzerland.

MoonLake Immunotherapeutics - Ordinary Shares - Class A

MoonLake Immunotherapeutics

MoonLake Immunotherapeutics is trending following a positive pre-BLA meeting with the FDA, which confirmed a clear regulatory path toward a late-2026 BLA submission with potential priority review. Community discourse is heavily focused on the company's best-in-class label potential, strong cash position through 2027, and anticipation of upcoming Phase 3 trial data readouts.

Odysight.ai, Inc. engages in the development and manufacture of customized visual solutions for organizations across a variety of industries in the form of micro cameras and supplementary technologies. Its devices can used across the medical, aerospace, industrial, research, and defense industries. The company was founded on March 22, 2013 and is headquartered in Omer, Israel.

Odysight.ai Inc

Odysight.AI Inc

Odysight.AI is currently capturing significant community attention following a cooperative research agreement with the U.S. Navy for AI-driven visual sensing technology. While bulls are excited by the potential for defense-sector growth and momentum, many traders are actively debating the sustainability of the price action and expressing skepticism regarding corporate dilution and past performance.

Rumble, Inc. engages in operating an online neutral video platform. It operates through the following geographical segments: United States, Canada, and Other. The company was founded in October 2013 by Chris Pavlovski and is headquartered in Longboat Key, FL.

Rumble Inc - Ordinary Shares - Class A

Rumble Inc

Rumble is trending as investors focus on the impending finalization of its acquisition of Northern Data and anticipation for upcoming earnings, which many in the community believe will validate a fundamental business pivot into AI and cloud infrastructure. While participants are actively debating the impact of a high short interest and the strategic backing of Tether, bullish sentiment remains anchored in the belief that these structural changes will drive a significant valuation re-rate.

Everspin Technologies, Inc. engages in the provision of magnetoresistive random access memory (MRAM) solutions. Its products include Toggle MRAM, Spin-transfer Torque MRAM, TMR Sensors, and Embedded MRAM. The company was founded by Saied Tehrani on May 16, 2008 and is headquartered in Chandler, AZ.

Everspin Technologies Inc

Everspin Technologies is experiencing a volatile surge driven by intense retail and institutional momentum, as traders draw parallels to the recent multi-week squeezes in larger memory sector peers. Investors are actively discussing the stock's potential as a low-float, high-upside play within the Edge AI and defense-infrastructure space, with many anticipating further upside despite discussions regarding legal challenges and valuation.

monday.com Ltd. engages in the business of operating a cloud-based visual work operating system that consists of modular building blocks that can be easily used and assembled to create software applications and work management tools and serves as a connective layer to integrate with various digital tools across an organization. It operates through the following geographical segments: United States, EMEA, United Kingdom, and Rest of the World. The company was founded by Roy Mann, Eran Kampf, and Eran Zinman in 2012 and is headquartered in Tel Aviv, Israel.

Monday.Com Ltd

Monday.com Ltd

Monday.com is facing heightened volatility and selling pressure following a revenue guidance miss, as investors weigh strong earnings beats against broader concerns regarding AI disruption in the enterprise SaaS sector. While many community members view the sharp price drop as a disconnect from the company's growth and cash-rich balance sheet, others remain cautious, debating whether established software platforms can effectively pivot or if they are vulnerable to emerging agentic AI competition.

GSI Technology, Inc. engages in the design, development and marketing of memory products primarily for the networking, and telecommunications markets. Its product includes Static Random Access Memory, or SRAM, which incorporated in networking and telecommunications equipment, such as routers, switches, wide area network infrastructure equipment, wireless base stations and network access equipment. It also offers services to the ongoing needs of the military, industrial, test and measurement equipment, automotive and medical markets for SRAMs .The company was founded by Lee-Lean Shu and Robert Yau in March 1995 and is headquartered in Sunnyvale, CA.

GSI Technology Inc

GSI Technology is seeing significant volatility and intense social media debate as investors weigh the company's AI semiconductor narrative against aggressive short-seller warnings of potential fraud and a history of failed product deliveries. The stock is currently being driven by heavy trading volume and polarized community sentiment, with bulls betting on its edge AI potential while bears highlight concerns over executive selling and the lack of concrete, independent benchmarks for their technology.

SELLAS Life Sciences Group, Inc. is a clinical stage biopharmaceutical company, which engages in the development and commercialization of immunotherapeutic for cancer indications. Its product pipeline includes galinpepimut-S. The company was founded by Angelos M. Stergiou on April 3, 2006 and is headquartered in New York, NY.

SELLAS Life Sciences Group Inc

SELLAS Life Sciences is trending as investors debate the timing of long-awaited Phase 3 data for its leukemia candidate, with the community actively split between concerns over trial delays and optimism regarding potential curative efficacy and institutional positioning. The core discussion centers on the lack of an announced 80th event as a sign of durable patient survival versus frustration over the companys silence and repeated requests for stock-based compensation.

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Hoth Therapeutics Secures European Authorization in Spain for HT-001 Phase 2a Trial as Interim Data Show Strong Efficacy in Cancer Patients

Hoth Therapeutics Secures European Authorization in Spain for HT-001 Phase 2a Trial as Interim Data Show Strong Efficacy in Cancer Patients Hoth Therapeutics Secures European Authorization in Spain...

Rewriting Fat Itself: Hoth Therapeutics May Be Targeting the Root of Metabolic Disease

Hoth Therapeutics (NASDAQ:HOTH) is stepping into one of the most competitive, and lucrative, arenas in biotech with data that suggests a fundamentally different approach to treating metabolic disease. Rather than simply helping patients lose weight, the company’s latest HT-VA study indicates it may be able to reprogram how the body creates and burns fat at the genetic level.

<ul class="summary-bullets"><li>REPL came under pressure after the FDA issued a second Complete Response Letter for RP1 with nivolumab in anti-PD-1-failed melanoma.</li><li>HOTH declined after a $2 million stock offering, along with attached warrants, raised dilution concerns despite recent pipeline updates.</li><li>ONCO is on a major slide after its reverse stock split, while its pending all-stock acquisition of Realbotix has yet to improve investor sentiment.</li></ul>Shares of Replimune (REPL), Hoth Therapeutics (HOTH), and Onconetix (ONCO) hit fresh 52-week lows on Monday following an FDA setback, a discounted offering, and a reverse split that underscored listing-compliance pressure.&nbsp;On Monday,&nbsp;<a href="https://stocktwits.com/symbol/REPL">REPL</a> fell 64%,&nbsp;<a href="https://stocktwits.com/symbol/HOTH">HOTH</a> slipped 1% and&nbsp;<a href="https://stocktwits.com/symbol/ONCO">ONCO</a> declined 27%, while the Health Care Select Sector SPDR Fund (XLV) rose 0.5%.<h2 class="st-heading-2">Regulatory Setback Pressures REPL Shares Again</h2>Pressure on REPL intensified recently after the U.S. Food and Drug Administration (FDA) issued a second Complete Response Letter (CRL) for its lead drug RP1 in combination with Nivolumab in anti-PD-1-failed melanoma, extending regulatory uncertainty that had already followed an earlier CRL last year.The latest development triggered a wave of&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/repl-stock-on-track-to-hit-all-time-lows-here-s-why-this-analyst-slashed-price-target-by-85/cZJFHklRIMD">analyst downgrades</a> across Wall Street. Jefferies said the company faces “a tough road ahead” following the FDA’s response, while BMO Capital said the CRL “lays bare the lack of alignment with the FDA and Replimune” throughout clinical development and warned the revised regulatory pathway may now require additional trials.JPMorgan called the outcome “disappointing,” adding it had previously believed “the totality of the data for RP1 warranted an approval.”&nbsp;<h2 class="st-heading-2">Stock Offering Weighs On HOTH Stock</h2>HOTH declined after the company announced earlier this month a stock offering priced at $0.7 per share, expected to generate about $2 million in gross proceeds before expenses, along with warrants exercisable at $0.85.The financing overshadowed pipeline updates over the past month, when the company reported interim Phase 2 progress for HT-001, a topical therapy to treat skin toxicities caused by epidermal growth factor receptor (EGFR) inhibitor cancer treatments. The trial showed that patients reached the primary efficacy endpoint by the sixth week and demonstrated “strong patient benefit across multiple clinically meaningful measures.”&nbsp;However, shares caught a break in after-hours trading on Monday, jumping over 60%, after preclinical data showed its&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/why-is-hoth-stock-up-after-hours-today/cZJ8gnKRIuz">HT-VA (GDNF) therapy</a> improved key gene markers linked to fat production and metabolism and outperformed Novo Nordisk's semaglutide on liver-fat regulation signals.<h2 class="st-heading-2">ONCO Slides Despite Realbotix Merger Progress</h2>ONCO shares have remained weak since the company implemented a 1-for-5 reverse stock split, effective March 25, to maintain compliance with Nasdaq’s minimum bid price requirement.The reverse split followed a September equity raise of $12.9 million through Series D preferred stock and warrants, with proceeds used in part to reduce outstanding debt and support working capital following the termination of a previously planned merger with Ocuvex.In February, the company entered into an agreement to acquire Realbotix in an all-stock transaction expected to close in the second half of 2026. Realbotix reported delivering its first Vinci-equipped humanoid robot to Ericsson this month and said the platform enables robots to “recognize returning users, recall previous conversations, and track engagement.” The company expects deliveries of 19 robots across March, April and May as production scales.<h2 class="st-heading-2">How Do Retail Traders Feel About REPL, HOTH, ONCO?</h2>On Stocktwits, retail sentiment for REPL was ‘bearish’ amid ‘extremely high’ message volume, while sentiment for both HOTH and ONCO remained ‘extremely bullish,’ also accompanied by ‘extremely high’ message volume.Over the past year, REPL has fallen 77%, HOTH down 36% and ONCO declining 97%, with all three stocks underperforming the broader XLV ETF, which rose 10% over the same period.For updates and corrections, email newsroom[at]stocktwits[dot]com.Read Next:&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/immunitybio-founder-fda-warning-letter-anktiva-ad-never-aired/cZJpYnYRIHR">ImmunityBio Founder Pushes Back After FDA Warning Letter Over Anktiva Claims — Says Ad 'Never Aired At All'</a>

On Monday alone, REPL plunged 64%, ONCO dropped 27%, and HOTH slipped 1%. (Photo credit: Getty Images)

REPL, HOTH, ONCO Stocks Hit 52-Week Lows: What's Driving The Selloff In These Biotech Plays?

On Monday alone, REPL plunged 64%, ONCO dropped 27%, and HOTH slipped 1%, underperforming the broader XLV healthcare ETF.

Equity

<ul class="summary-bullets"><li>HT-VA outperformed Danish drug Novo Nordisk’s blockbuster semaglutide drug in key gene expression markers tied to liver fat regulation, the company said.</li><li>The company is now looking to advance the drug in additional preclinical validation studies.</li></ul> Shares of Hoth Therapeutics, Inc. (HOTH) jumped 70% after-hours on Monday after data from the company’s preclinical trial evaluating its experimental treatment HT-VA showed significant improvements in key genes responsible for fat production and fat metabolism.The company said that the trial showed statistically significant reduction in genes driving fat production and increased fat metabolism, positioning HT-VA as therapy for metabolic-associated fatty liver disease and obesity.The company is now looking to advance the drug in additional preclinical validation studies and evaluate clinical development pathways for metabolic and liver diseases, while also exploring strategic partnerships and collaborations to accelerate development.<h2 class="st-heading-2">Study Takeaways</h2>HT-VA outperformed Danish drug Novo Nordisk’s (NVO) blockbuster semaglutide drug in key gene expression markers tied to liver fat regulation, the company said, while adding that it also demonstrated broad metabolic impact at the genetic levels beyond just weight reduction."These results demonstrate that GDNF (HT-VA) is not simply reducing fat, but fundamentally reprogramming how the body produces and metabolizes fat at the genetic level. The ability to shut down fat creation while activating fat metabolism differentiates GDNF from existing therapies, including GLP-1 agonists," said CEO Robb Knie.HT-VA is part of Hoth’s efforts to move beyond its core dermatology and oncology pipeline, which includes candidates aimed at treating atopic dermatitis and mast-cell derived cancers.<h2 class="st-heading-2">How Did Retail Traders React?</h2>On Stocktwits, retail sentiment around HOTH stock jumped from ‘bearish’ to ‘neutral’ territory over the past 24 hours, while message volume remained at ‘high’ levels.A Stocktwits user expressed optimism for the rally driving the share price past the $1 mark.<stembedurl>https://www.stocktwits.com/Avi_thind/message/650169883</stembedurl><a href="https://stocktwits.com/symbol/HOTH">HOTH stock</a> has lost 38% of its value over the past 12 months.&nbsp;Read More: <a href="https://stocktwits.com/news-articles/markets/equity/syre-stock-marks-best-session-in-about-3-years/cZJ8B3cRIuw">SYRE Stock Marks Best Session In About 3 Years — Here’s Why</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Why Is HOTH Stock Up 70% After-Hours Today?

Hoth Therapeutics said that its preclinical trial evaluating its experimental treatment HT-VA showed significant improvements in key genes responsible for fat production and fat metabolism. 

Hoth Therapeutics (HOTH) Reports Positive HT-VA CRADA Data: GDNF Reprograms Liver Fat Metabolism, Shuts Down Fat-Creation Gene and Activates Fat-Burning Pathways, Outperforming Semaglutide

Hoth Therapeutics (HOTH) Reports Positive HT-VA CRADA Data: GDNF Reprograms Liver Fat Metabolism, Shuts Down Fat-Creation Gene and Activates Fat-Burning Pathways, Outperforming Semaglutide Hoth Therapeutics (HOTH) Reports Positive HT-VA CRADA Data: GDNF Reprograms Liver Fat Metabolism, Shuts Down...

Hoth Therapeutics Announces Closing of $2.0 Million Registered Direct Offering

Hoth Therapeutics Announces Closing of $2.0 Million Registered Direct Offering Hoth Therapeutics Announces Closing of $2.0 Million Registered Direct Offering PR Newswire NEW YORK, April 2, 2026 NEW...

Hoth Therapeutics Announces $2.0 Million Registered Direct Offering

Hoth Therapeutics Announces $2.0 Million Registered Direct Offering Hoth Therapeutics Announces $2.0 Million Registered Direct Offering PR Newswire NEW YORK, April 1, 2026 NEW YORK, April 1, 2026 /PRNewswire/ -- Hoth Therapeutics, Inc. (Nasdaq: HOTH), a clinical-stage biopharmaceutical company...

Hungary Approves Trial Expansion as HT-001 Meets Primary Endpoint in Interim Analysis with Patients Reaching ARIGA 1 by Week Six

Hungary Approves Trial Expansion as HT-001 Meets Primary Endpoint in Interim Analysis with Patients Reaching ARIGA 1 by Week Six Hungary Approves Trial Expansion as HT-001 Meets Primary Endpoint in...

Hoth Therapeutics Announces Issuance of Chinese Patent for Cancer Cell-Targeting Technology

Hoth Therapeutics Announces Issuance of Chinese Patent for Cancer Cell-Targeting Technology Hoth Therapeutics Announces Issuance of Chinese Patent for Cancer Cell-Targeting Technology PR Newswire NEW...

Hoth Therapeutics Deploys OpenClaw AI Platform to Accelerate Drug Discovery

Hoth Therapeutics Deploys OpenClaw AI Platform to Accelerate Drug Discovery Hoth Therapeutics Deploys OpenClaw AI Platform to Accelerate Drug Discovery PR Newswire NEW YORK, March 26, 2026 NEW YORK...

Hoth Therapeutics, Inc. engages in the development of new generation therapies for dermatological disorders. Its product pipeline focuses on potential treatments for indications including atopic dermatitis (also known as eczema), chronic wounds, psoriasis, asthma, and acne. It offers the BioLexa Platform, a drug compound platform for the treatment of eczema. The company was founded by Robbie Knie, Matthew D. Eitner, and James Ahern on May 16, 2017 and is headquartered in New York, NY.

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