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ImmunityBio, Inc. is a clinical stage immunotherapy company. It develops next generation therapies that drive immunogenic mechanisms for defeating cancers and infectious diseases. The company's immunotherapy platform activates both the innate and adaptive immune systems to create long term immunological memory. ImmunityBio was founded by Patrick Soon-Shiong in 2014 and is headquartered in San Diego, CA.

ImmunityBio Inc

ImmunityBio is trending following constructive discussions with the FDA regarding a resubmission path for ANKTIVA in bladder cancer, complemented by significant international approvals and strategic partnerships like those recently established in Saudi Arabia for broader cancer indications. This development, coupled with high short interest, is fueling widespread community excitement about a potential paradigm shift in oncology and intense speculation regarding a short squeeze amidst growing calls for expedited access to these innovative treatments.

SSgA Active Trust - SPDR S&P 500 ETF Trust

The SPDR S&P 500 ETF Trust is trending as President Trump's threats of new tariffs on European nations over Greenland escalate geopolitical tensions, leading to a risk-off market sentiment. The community is divided, with some anticipating a significant market pullback, while others view it as a 'buy the dip' opportunity, also noting a Japan-led bond sell-off as a contributing factor. This environment is fueling discussions about broader market volatility and a flight to safe-haven assets.

Invesco Capital Management LLC - Invesco QQQ Trust Series 1

QQQ is trending as former President Trump's renewed threats of tariffs on NATO allies, particularly over the acquisition of Greenland, spark fears of a trade war with Europe. This escalating geopolitical tension is causing widespread market jitters and calls for caution, though many investors are also discussing it as a potential "buy the dip" opportunity for growth stocks.

Novavax, Inc. Is a biotechnology company, which engages in the discovery, development, and commercialization of recombinant vaccines. The company was founded in 1987 and is headquartered in Gaithersburg, MD.

Novavax, Inc.

Novavax Inc

Novavax is a major talking point following its J.P. Morgan conference appearance, where investors are eagerly seeking clarity on its strategy for advancing the Matrix-M adjuvant technology and securing new collaborations. Community sentiment is sharply focused on management's pace in realizing pipeline potential, including a recent Pfizer agreement and ongoing Sanofi ventures, with an activist investor's growing stake and significant short interest adding to the intense market watch.

BlackRock Institutional Trust Company N.A. - iShares 20+ Year Treasury Bond ETF

iShares 20+ Year Treasury Bond ETF

TLT is trending amid intense debate surrounding the Federal Reserve's independence, fueled by a federal probe into its Chair and the administration's aggressive policy maneuvers impacting bond markets. Investors are actively discussing whether long-term treasuries offer a crucial hedge against a potential economic slowdown or face further headwinds from escalating national debt and geopolitical uncertainty.

Corvus Pharmaceuticals, Inc. engages in the development of immune modulator product candidates with the potential to treat solid cancers, T-cell lymphomas, autoimmune diseases, and infectious diseases. Its product pipeline includes B Cell Activator and Anti-CD73, Adenosine Production Inhibitor Anti-CD73, ITK Inhibitor, A2AR Inhibitor, Anti-CXCR2, and A2BR Inhibitor. The company was founded by Richard A. Miller, Peter A. Thompson, Joseph J. Buggy, and Erik Verner on January 27, 2014 and is headquartered in South San Francisco, CA.

Corvus Pharmaceuticals Inc

Corvus Pharmaceuticals is trending after announcing positive data from its placebo-controlled Phase 1 clinical trial of soquelitinib for atopic dermatitis, showing strong efficacy. The community is actively discussing the oral ITK inhibitor's potential in a large market, with many anticipating significant revaluation and partnership opportunities for its novel mechanism of action.

Trump Media & Technology Group Corp. engages in operating social media and in the technology business. Its brands include TRUTH Social, TMTG+ and TMTG News. The company was founded on March 28, 2024 and is headquartered in Sarasota, FL.

Trump Media & Technology Group Corp.

Trump Media & Technology Group Corp. (DJT) is seeing heightened conversation due to recent developments surrounding Trump's assertive stance on Greenland and reactions to a perceived Nobel Peace Prize snub, which has sparked discussions of new tariffs on European nations. The community is actively debating the potential for increased market volatility, geopolitical instability, and the broader economic ramifications of these actions. This ongoing dialogue underscores intense political polarization and its influence on market sentiment.

Netflix, Inc. engages in providing entertainment services. It also offers activities for leisure time, entertainment video, video gaming, and other sources of entertainment. It operates through the United States and International geographic segments. The company was founded by Marc Randolph and Wilmot Reed Hastings on August 29, 1997 and is headquartered in Los Gatos, CA.

Netflix Inc.

Netflix Inc

Netflix is currently a major talking point among investors, primarily driven by its upcoming earnings report and the proposed all-cash acquisition of Warner Bros. Discovery assets, which has sparked a debate over potential growth versus debt concerns. The community is closely watching for strong ad-tier performance and subscriber metrics, particularly after a previous tax-related earnings miss, with sentiment split on whether recent oversold conditions signal a significant rebound or continued volatility.

AppLovin Corp. engages in the development and operation of a mobile marketing platform. It offers AppDiscovery, MAX, Adjust, and SparkLabs. Its software-based platform caters to mobile application developers to improve the marketing and monetization of applications. The company was founded by Andrew Karam, John Krystynak, and Adam Foroughi in 2011 and is headquartered in Palo Alto, CA.

Applovin Corp - Ordinary Shares - Class A

Applovin Corp

Applovin (APP) is actively trending amid recent allegations of money laundering and illicit financial ties, triggering a sharp sell-off across the stock. Despite this, community sentiment is divided, with many dismissing the claims as a coordinated short attack ahead of strong earnings, while others are seizing the opportunity to buy into the fundamentally strong AI-powered ad platform.

SPDR Gold Trust - SPDR Gold Shares

SPDR Gold Shares ETF

SPDR Gold Shares ETF (GLD) is trending strongly as renewed geopolitical tensions, including recent tariff threats concerning European countries over Greenland, fuel a broad flight to safety. The community views gold as a crucial hedge against eroding fiat currency confidence and economic instability, driving prices to consistent new highs. Many are discussing significant further appreciation as these global uncertainties persist.

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<ul class="summary-bullets"><li>Saylor’s comments follow JPMorgan’s warning that MSCI may remove MicroStrategy from major equity indices in January.</li><li>JPMorgan noted potential outflows of $2.8 billion if excluded from MSCI, and $8.8 billion if other index providers follow suit.</li><li>Saylor stated that funds and trusts passively hold assets, and holding companies sit on investments, whereas Strategy actively creates and operates.</li></ul>Michael Saylor, executive chairman of Strategy (MSTR), addressed market concerns over potential index exclusion, emphasizing that index classification “doesn’t define” MSTR.“Strategy is not a fund, not a trust, and not a holding company. We’re a publicly traded operating company with a $500 million software business and a unique treasury strategy that uses Bitcoin (BTC) as productive capital,” Saylor&nbsp;<a class="st-link-external" target="_blank" rel="noopener noreferrer nofollow" href="https://x.com/saylor/status/1991875241107222701">wrote</a> on X.<figure class="image"><img style="aspect-ratio:835/977;" src="https://news.stocktwits-cdn.com/Screenshot_2025_11_21_095808_png_1f4e54d94e.webp" alt="Screenshot 2025-11-21 095808.png" width="835" height="977"><figcaption>@Saylor/X</figcaption></figure><a href="http://stocktwits.com/symbol/MSTR">MSTR’s stock</a> dipped 1.7% as&nbsp;<a href="http://stocktwits.com/coins/bitcoin">Bitcoin’s price</a> traded at $84,000, rebounding from an intra-day low of around $80,500. Retail sentiment around Strategy on Stocktwits trended in ‘bullish’ territory with chatter at ‘extremely high’ volumes over the past day. Meanwhile, Bitcoin was the top trending on the platform as chatter rose to ‘extremely high’ from ‘high’ levels amid retail sentiment in the ‘bearish’ zone.<h2 class="st-heading-2">Index Exclusion Risks Loom</h2>Saylor’s remarks came after JPMorgan&nbsp;<a href="https://stocktwits.com/news-articles/markets/equity/jp-morgan-warns-of-over-8-b-strategy-selloff-risk-as-stock-bleeds-for-7-straight-weeks/cLPMOW3REau">noted</a> that Strategy could face exclusion from major equity indices as the January MSCI decision approaches. “Outflows could amount to $2.8 billion if Strategy is excluded from MSCI indices, and $8.8 billion from all other equity indices if other providers follow MSCI,” the firm said in its note.<blockquote>“Index classification doesn’t define us.”– Michael Saylor, Executive Chairman, Strategy</blockquote>Saylor stated that Strategy operates differently from funds, trusts, or holding companies. “No passive vehicle or holding could do what we’re doing,” he wrote. “Funds and trusts passively hold assets, while holding companies sit on investments. Our team is building a new kind of enterprise—a Bitcoin-backed structured finance company capable of innovating in both capital markets and software.”He reiterated that the MSTR’s strategy is long-term and rooted in Bitcoin-backed financial innovation, with a focus on active management and operational growth.Read also:&nbsp;<a href="https://stocktwits.com/news-articles/markets/cryptocurrency/bitcoin-etfs-hit-record-outflows-average-investor-now-in-the-red/cLPMoktREOm">Bitcoin ETFs Hit Record Monthly Outflows In November – Average Investor Now in the Red, Says Analyst</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

Strategy executive chairman and co-founder Michael Saylor speaks at the Bitcoin 2021 Convention at the Mana Convention Center in Wynwood on June 04, 2021 in Miami, Florida. (Photo by Joe Raedle/Getty Images)

Michael Saylor Says Index Classification ‘Doesn’t Define’ MSTR Amid MSCI Exclusion Concerns

In a post on X, MSTR’s executive chairman stated that Strategy is an operating company, not a fund, trust, or holding company.

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